Edinburgh Research Explorer

Prof Rustam Al-Shahi Salman, MA PhD FRCP Edin

Personal Chair of Clinical Neurology

Profile photo

Willingness to take Ph.D. students: Yes

Intracerebral haemorrhage: epidemiology, cause, and treatment

Education / Academic qualification

Bachelor of Medicine, University of Cambridge
Bachelor of Surgery, University of Cambridge
Bachelor of Arts, University of Cambridge
Doctor of Philosophy (PhD), University of Edinburgh
The epidemiology of brain arteriovenous malformations in adults

Professional Qualifications

Fellow of the Royal College of Physicians Edinburgh, FRCP Edin
Member of the Royal College of Physicians, MRCP (UK)

Area of Expertise

Research expertisestroke, intracerebral haemorrhage

Biography

I am an academic clinician interested in anything that bleeds in the brain. My career is dedicated to improving the outcome for adults who have diseases that may cause, or have caused, intracranial hemorrhage. I focus on caring for people with these conditions, auditing their care, and better understanding cause, prognosis and treatment by leading the University of Edinburgh’s Research to Understand Stroke due to Hemorrhage (RUSH) programme.

Current Research Interests

  • Therapeutic dilemmas about antithrombotic drugs after intracranial haemorrhage (RESTART and SoSTART randomised controlled trials)
  • Causes and consequences of stroke due to intracerebral haemorrhage (LATCH community-based cohort study and LINCHPIN genetic, imaging, and neuropathology study)
  • Prognosis and treatment of intracranial vascular malformations in adults (SAIVMs population-based cohort study)

My research in a nutshell

The deadliest type of stroke is caused by spontaneous bleeding from blood vessels into the brain, known as brain haemorrhage. This disease affects about 10,000 adults in the UK, and about 2 million adults in the world, each year. Two out of five people affected die within one month of the bleed and another two remain dependent on their families or carers, leaving only one person out of five independent.

I use a variety of clinical research designs, including systematic reviews, case-control and cohort studies, and randomised controlled trials to better understand the causes, consequences, and treatment of brain haemorrhage.

Positions available

I am keen to attract motivated clinical research fellows to work on the projects that I am running, or to set up projects of their own. I have a track record of obtaining independently-funded fellowships from the MRC, and my department has a programme dedicated to supporting trainees obtain such fellowships: http://www.ed.ac.uk/schools-departments/clinical-brain-sciences/postgraduate-training

Websites

Administrative Roles

  • European Stroke Organisation, Board of Directors
  • Parkinson’s UK Cohort Studies Council, Vice-Chair
  • Stroke Association in Scotland Advisory Committee
  • Member of the Secretary of State for Transport’s Honorary Medical Advisory Panel on Driving and Disorders of the Nervous system
  • Trials Senior Editor
  • Cochrane Stroke Group Editorial Board
  • Evidence-based Preclinical Medicine Editorial Board
  • Scientific committee chairperson, British Association of Stroke Physicians
  • European Stroke Organisation Trials Network Committee (advisory member)
  • Dutch CAA Foundation Scientific Advisory Board
  • Chair of British Neurological Surveillance Unit, Association of British Neurologists
  • Clinical Research & Academic Committee, Association of British Neurologists
  • Angioma Alliance Scientific Advisory Board

Research activities & awards

  1. Member of the Efficacy and Mechanism Evaluation (EME) programme's Board

    Activity: External academic engagementMembership of peer review panel or committee

  2. MSc Clinical Trials (Edinburgh)

    Activity: Participation in conference, seminar or training courseParticipation in workshop, seminar, course

  3. RCPE Stroke Symposium

    Activity: External academic engagementContribution to the work of national or international committees and working groups

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