The tumour microenvironment is abnormal and one of its consequences is that blood vessels are compressed. Vessel compression correlates with reduced survival rates, while decompression of vessels improves tissue oxygenation as well as increases survival rates. It was previously shown that vessel compression contributes, at a single vascular bifurcation, to the increase of heterogeneity of red blood cell transport. This dataset contains the result of a simulation of blood flow (Poiseuille flow) through a compressed network, showing the effect of vessel compression on haematocrit distribution. It additionally contains the critical bifurcations in the network that are responsible for diverting blood flow away from the compressed region.
|Date made available
|16 Nov 2023