Cell growth dataset for "Suppression of bacterial cell death underlies the antagonistic interaction between ciprofloxacin and tetracycline in Escherichia coli"

  • James Broughton (Data Collector)
  • Louise Goossens (Data Collector)
  • Meriem El Karoui (Project Leader)
  • Achille Fraisse (Researcher)
  • Livia Scorza (Data Manager)

Dataset

Description

This dataset contains growth data of E. coli cells measured by optical density at a wavelenght of 600 nm (OD600) to determine the conditions where the combination of ciprofloxacin (CIP) and tetracycline (TET) is antagonistic (or suppressive), using a medium that supports fast, intermediate and slow growth (M9 based medium supplemented with: glucose and amino acid, glucose, and glycerol, respectively).
Two types of assays were performed: a checkerboard assay with a 2-dimension gradient of antibiotic concentrations shown in "Fig-S1-Growth_rates-Checkerboard_assay.zip", and bulk growth rates assay shown in "Fig-S2-Bulk_doubling_rates-Bioreactor.zip".
These experiments are presented in the supplementary figures of the following manuscript published as preprint in bioRxiv: https://doi.org/10.1101/2024.04.18.590101.

Data Citation

Broughton, J., Goossens, L., El Karoui, M., & Fraisse, A. (2024). Cell growth dataset for "Suppression of bacterial cell death underlies the antagonistic interaction between ciprofloxacin and tetracycline in Escherichia coli" (Version v2) [Data set]. Zenodo. https://doi.org/10.5281/zenodo.15311905
Date made available30 Apr 2024
PublisherZenodo

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