Comprehensive transcriptional profiling of the gastrointestinal tract of ruminants from birth to adulthood

One of the most significant physiological challenges to neonatal and juvenile ruminants is the development and establishment of the rumen. Using a subset of RNA-Seq data from our high-resolution atlas of gene expression in sheep (Ovis aries) we have provided the first comprehensive characterisation of transcription of the entire gastrointestinal (GI) tract during the transition from pre-ruminant to ruminant. The dataset comprises 168 tissue samples from sheep at four different time points (birth, one week, 8 weeks and adult). Included here are the gene expression estimates as transcripts per million (TPM) for individual sheep (Table S4) and averaged across individuals (Table S1).

Bush, Stephen J.; McCulloch, Mary E. B.; Muriuki, Charity; Salavati, Mazdak; Davis, Gemma M.; Farquhar, Iseabail L.; Lisowski, Z. M.; Archibald, Alan L.; Hume, D. A.; Clark, E. L.. (2018). Comprehensive transcriptional profiling of the gastrointestinal tract of ruminants from birth to adulthood, [dataset]. The Roslin Institute. University of Edinburgh.