Data from: Existing infection facilitates establishment and density of malaria parasites in their mosquito vector

Very little is known about how vector-borne pathogens interact within their vector and how this impacts transmission. Here we show that mosquitoes can accumulate mixed strain malaria infections after feeding on multiple hosts. We found that parasites have a greater chance of establishing and reach higher densities if another strain is already present in a mosquito. Mixed infections contained more parasites but these larger populations did not have a detectable impact on vector survival. Together these results suggest that mosquitoes taking multiple infective bites may disproportionally contribute to malaria transmission. This will increase rates of mixed infections in vertebrate hosts, with implications for the evolution of parasite virulence and the spread of drug-resistant strains. Moreover, control measures that reduce parasite prevalence in vertebrate hosts will reduce the likelihood of mosquitoes taking multiple infective feeds, and thus disproportionally reduce transmission. More generally, our study shows that the types of strain interactions detected in vertebrate hosts cannot necessarily be extrapolated to vectors.

survival of mosquitoes
Survival and infection status data for mosquitoes.
vector.mortality.csv
Parasite densities in primary infections
First.infection.as.focal.csv
Establishment of infection from second feed
Data showing that mosquitoes can accumulate infections from multiple feeds.
establishment.of.2nd.infection.csv
Parasite density in infections established from a secondary feed
density.of.2nd.infections.csv

Pollitt, Laura C.; Bram, Joshua T.; Blanford, Simon et al. (2016). Data from: Existing infection facilitates establishment and density of malaria parasites in their mosquito vector [Dataset]. Dryad. https://doi.org/10.5061/dryad.8nr13