Abstract
Respiratory syncytial virus associated acute respiratory infection (RSV-ARI) constitutes a substantial disease burden in adults, especially in those with comorbidities. We aimed to identify all studies worldwide investigating the disease burden of RSV-ARI in adults with comorbidities.
We estimated the community incidence, hospitalisation rate and in-hospital case fatality ratio (hCFR) of RSV-ARI in adults with comorbidities based on a systematic review of studies published between January 1996 and March 2020. We also investigated the strength of the association between RSV-ARI and any comorbidity in adults. Meta-analyses based on random effects model were carried out to generate the estimates.
The disease burden of RSV-ARI among adults with comorbidity is substantial with limited data available, especially for developing countries; appropriate prevention and management strategies are needed to reduce this burden.
We estimated the community incidence, hospitalisation rate and in-hospital case fatality ratio (hCFR) of RSV-ARI in adults with comorbidities based on a systematic review of studies published between January 1996 and March 2020. We also investigated the strength of the association between RSV-ARI and any comorbidity in adults. Meta-analyses based on random effects model were carried out to generate the estimates.
The disease burden of RSV-ARI among adults with comorbidity is substantial with limited data available, especially for developing countries; appropriate prevention and management strategies are needed to reduce this burden.
Data Citation
University of Edinburgh. Edinburgh Medical School. (2020). Disease burden estimates of RSV associated with acute respiratory infections in adults with comorbidity, 1996-2020 [dataset]. https://doi.org/10.7488/ds/2941
| Date made available | 1 Dec 2021 |
|---|---|
| Publisher | Edinburgh DataShare |
| Temporal coverage | Jan 1996 - Mar 2020 |
| Geographical coverage | UNITED KINGDOM,AU,AUSTRALIA,BG,BULGARIA,CA,CANADA,CN,CHINA,CZECHIA,FR,FRANCE,DE,GERMANY,IT,ITALY,RU,RUSSIAN FEDERATION,ZA,SOUTH AFRICA,ES,SPAIN,SE,SWEDEN,US,UNITED STATES,CZ,UK |