DNA modulates solvent isotope effects in a nanopore 

Ion current recordings, raw data as recorded in PClamp 10.2 software. NOTE: Some files are in Axon(TM) Binary Format (ABF), a format proprietary to Molecular Devices.

Here we investigate the modulation of solvent isotope effects by the entry of DNA molecules into individual α-haemolysin nanopores. Solvent isotope effects in D2O versus H2O were enhanced (kH/kD ≈ 1.6) compared to the bulk (kH/kD ≈ 1.2), except when the pore was most blocked (kH/kD ≤ 1.1).

Watson, Matthew; Cockroft, Scott. (2015). DNA modulates solvent isotope effects in a nanopore, 2013-2015 [dataset]. University of Edinburgh, EaStCHEM School of Chemistry. http://dx.doi.org/10.7488/ds/277.