Frequency distribution of cytokine and associated transcription factor single nucleotide polymorphisms in Zimbabweans: impact on schistosome infection and cytokine levels

  • Takafira Mduluza (Creator)
  • Andrew Hanton (Creator)
  • Fiona Scott (Creator)
  • Katharina Stenzel (Creator)
  • Norman Nausch (Creator)
  • Grace Zdesenko (Creator)
  • Francisca Mutapi (Creator)

Dataset

Abstract

This dataset contains demographic, parasitological, immunological, and single nucleotide polymorphism (SNP) data from 850 Zimbabwean individuals participating in a longitudinal study of urogenital schistosomiasis (S. haematobium) infection. Individuals from an S. haematobium-endemic region were genotyped for 35 SNPs across genes encoding cytokines and associated transcription factors, and the role of these SNPs in modulating susceptibility to S. haematobium infection and cytokine production was analysed.

Data Citation

Hanton, Andrew; Scott, Fiona; Stenzel, Katharina; Nausch, Norman; Zdesenko, Grace; Mduluza, Takafira; Mutapi, Francisca. (2022). Frequency distribution of cytokine and associated transcription factor single nucleotide polymorphisms in Zimbabweans: impact on schistosome infection and cytokine levels, [dataset]. University of Edinburgh. School of Biological Sciences. Institute of Immunology and Infection Research. https://doi.org/10.7488/ds/3466.
Date made available19 Oct 2022
PublisherEdinburgh DataShare
Geographical coverageZW,Murewa District, Mashonaland East Province, Zimbabwe,ZIMBABWE

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