Genetically independent phenotype analysis identifies LPA and VCAM1 as drug targets for human ageing

Paul Timmers (Creator)
M. Akiyama (Creator)
TTJ Kiiskinen (Creator)
W. Zhou (Creator)
S Hwang (Creator)
The Biobank Japan Project (Creator)
The FinnGen Study (Creator)
J Deelen (Creator)
D. Levy (Creator)
A Ganna (Creator)
Y. Okada (Creator)
C. Yao (Creator)
ES Tiys (Creator)
S Sakaue (Creator)
Peter Joshi (Creator)
Jim Wilson (Creator)
YA Tsepilov (Creator)

Dataset

Abstract

Data supporting the manuscript Timmers et. al (In submission).

Data Citation

Timmers, PRHJ et al. (2021). Genetically independent phenotype analysis identifies LPA and VCAM1 as drug targets for human ageing, [dataset]. University of Edinburgh.

Date made available	21 Jan 2022
Publisher	Edinburgh DataShare
Geographical coverage	UNITED KINGDOM,UK

DOI
10.7488/ds/2972

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Genetically independent phenotype analysis identifies LPA and VCAM1 as drug targets for human ageing Paul R. H. J. Timmers, Evgeny S. Tiys, Saori Sakaue, Masato Akiyama, Tuomo T. J. Kiiskinen, Wei Zhou, Shih-Jen Hwang, Chen Yao, The Biobank Japan Project, FinnGen Study, Joris Deelen, Daniel Levy, Andrea Ganna, Yoichiro Kamatani, Yukinori Okada, Peter K. Joshi, James F. Wilson, Yakov A. Tsepilov bioRxiv 2021.01.22.427837; doi: https://doi.org/10.1101/2021.01.22.427837 This article is a preprint and has not been certified by peer review

1 Article

Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging
Timmers, P. R. H. J., Tiys, E. S., Sakaue, S., Akiyama, M., Kiiskinen, T. T. J., Zhou, W., Hwang, S.-J., Yao, C., Kamatani, Y., Zhou, W., Deelen, J., Levy, D., Ganna, A., Kamatani, Y., Okada, Y., Joshi, P. K., Wilson, J. F. & Tsepilov, Y. A., 20 Jan 2022, In: Nature Aging. 2, 1, p. 19-30
Research output: Contribution to journal › Article › peer-review

Open Access
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Cite this

Timmers, P. (Creator), Akiyama, M. (Creator), Kiiskinen, T. (Creator), Zhou, W. (Creator), Hwang, S. (Creator), Biobank Japan Project, T. (Creator), FinnGen Study, T. (Creator), Deelen, J. (Creator), Levy, D. (Creator), Ganna, A. (Creator), Okada, Y. (Creator), Yao, C. (Creator), Tiys, E. (Creator), Sakaue, S. (Creator), Joshi, P. (Creator), Wilson, J. (Creator), Tsepilov, Y. (Creator) (21 Jan 2022). Genetically independent phenotype analysis identifies LPA and VCAM1 as drug targets for human ageing. Edinburgh DataShare. 10.7488/ds/2972

Genetically independent phenotype analysis identifies LPA and VCAM1 as drug targets for human ageing

Abstract

Data Citation

DOI

Access Dataset

Research output

Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging

Cite this