Genome-wide association summary statistics of antidepressant treatment resistance meta-analysis

Ella Wigmore (Creator)
Jonathan Hafferty (Creator)
Lynsey Hall (Creator)
David Howard (Creator)
Toni-Kim Clarke (Creator)
Chiara Fabbri (Creator)
Cathryn Lewis (Creator)
Lauren Navrady (Creator)
Mark Adams (Creator)
Yanni Zeng (Creator)
Archie Campbell (Creator)
Jude Gibson (Creator)
Pippa Thomson (Creator)
Caroline Hayward (Creator)
Blair Smith (Creator)
Lynne Hocking (Creator)
Sandosh Padmanabhan (Creator)
Ian Deary (Creator)
David Porteous (Creator)
Ole Mors (Creator)
Manuel Mattheisen (Creator)
Rudolf Uher (Creator)
Kristin Nicodemus (Creator)
Andrew McIntosh (Creator)

Dataset

Abstract

Data from Wigmore et al "Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP". The Pharmacogenomics Journal 20, 329–341 (2020) DOI:10.1038/s41397-019-0067-3

This dataset consists of two sets of GWAS summary statistics:

- case-control analysis of treatment resistance phenotype in the Generation Scotland and GENDEP samples (inverse variance weighted meta-analysis). Cases = 358, Controls = 3855.
- quantitative stages of resistance phenotype in Generation Scotland. N = 3452.

Data Citation

Wigmore, Ella; Hafferty, Jonathan; Hall, Lynsey; Howard, David; Clarke, Toni-Kim; Fabbri, Chiara; Lewis, Cathryn; Uher, Rudolf; Navrady, Lauren; Adams, Mark; Zeng, Yanni; Campbell, Archie; Gibson, Jude; Thomson, Pippa; Hayward, Caroline; Smith, Blair; Hocking, Lynne; Padmanabhan, Sandosh; Deary, Ian; Porteous, David; Mors, Ole; Mattheisen, Manuel; Nicodemus, Kristin; McIntosh, Andrew. (2020). Genome-wide association summary statistics of antidepressant treatment resistance meta-analysis, [dataset]. University of Edinurgh. Centre for Clinical Brain Sciences. Department of Psychiatry. https://doi.org/10.7488/ds/2791.

Date made available	31 Mar 2020
Publisher	Edinburgh DataShare
Geographical coverage	Scotland,UK,UNITED KINGDOM

DOI
10.7488/ds/2791

1 Article

Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP
Wigmore, E., Hafferty, J., Hall, L., Howard, D. M., Clarke, T-K., Fabbri, C., Lewis, C. M., Uher, R., Navrady, L., Adams, M. J., Zeng, Y., Campbell, A., Gibson, J., Thomson, P., Hayward, C., Smith, B. H., Hocking, L. J., Padmanabhan, S., Deary, I., Porteous, D., & 4 othersMors, O., Mattheisen, M., Nicodemus, K. & McIntosh, A., 31 Jan 2019, In: Pharmacogenomics Journal.
Research output: Contribution to journal › Article › peer-review

Open Access
File

1 Finished

Stratifying Resilience and Depression Longitudinally
McIntosh, A., Deary, I., Evans, K., Haley, C. & Porteous, D.
UK-based charities
1/01/15 → 30/06/21
Project: Research

Cite this

Wigmore, E. (Creator), Hafferty, J. (Creator), Hall, L. (Creator), Howard, D. (Creator), Clarke, T. (Creator), Fabbri, C. (Creator), Lewis, C. (Creator), Navrady, L. (Creator), Adams, M. (Creator), Zeng, Y. (Creator), Campbell, A. (Creator), Gibson, J. (Creator), Thomson, P. (Creator), Hayward, C. (Creator), Smith, B. (Creator), Hocking, L. (Creator), Padmanabhan, S. (Creator), Deary, I. (Creator), Porteous, D. (Creator), Mors, O. (Creator), Mattheisen, M. (Creator), Uher, R. (Creator), Nicodemus, K. (Creator), McIntosh, A. (Creator) (31 Mar 2020). Genome-wide association summary statistics of antidepressant treatment resistance meta-analysis. Edinburgh DataShare. 10.7488/ds/2791

Genome-wide association summary statistics of antidepressant treatment resistance meta-analysis

Abstract

Data Citation

DOI

Research output

Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP

Projects

Stratifying Resilience and Depression Longitudinally

Cite this