GenOMICC WGS summary statistics



GWAS summary statistics from 7,491 critically ill patients from COVID-19 and 48,400 population controls: European(EUR) 5,989/42,891; South Asian(SAS) 788/3,793; African(AFR) 440/1,350; East Asian(EAS) 274/366. GWAS models were calculated with SAIGE using a logisitic mixed-model regression. A trans-ancestry meta-analysis was performed using inverse-variant weighted fixed-effects. Ancestry-specific and trans-ancestry summary statistics are available with MAF>0.01. TWAS was performed using GTEx v8 gene expression data for lung and blood and an all-tissue meta-analysis. Summary statistics for tissue-specific and meta-TWAS are available

Data Citation

Pairo-Castineira, Erola; Baillie, J; Kousathanas, Athanasios; Caufield, Mark J.. (2022). GenOMICC WGS summary statistics, 2020-2021 [dataset]. University of Edinburgh. Roslin Institute.
Date made available16 Feb 2022
PublisherEdinburgh DataShare
Temporal coverageMar 2020 - Jul 2021

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