Production system drivers of antibiotic resistance at the human-animal interface in Uganda



This is dataset and code are part of supplementary data for a manuscript titled "Production system drivers of antibiotic resistance at the human-animal interface in Uganda". The role of livestock production systems in the epidemiology of antibacterial resistance (ABR) in sympatric human and livestock populations is poorly understood. Here, we examine ABR at the farmer-pig interface of Uganda, where the pig sector is rapidly growing, to quantify rates of resistance, understand associated human- and livestock-related factors, and investigate cross-species transmission.

The motivation of this is to improve our understanding of the role of livestock production systems in the emergence and transmission of AMR, this paper uses phenotypic resistance profile from sentinel bacteria E.coli and Klebsiella, recovered from a faecal sample collected from farmers and their pigs across a one year longitudinal study. This is mapped to AMR gene carriage of four selected genes measured using QPCR. Using the Metadata, we examine drivers of resistance in this setting, we also use the prevalence and sharing of MDR profiles to infer transmission.
Date made available30 May 2023
PublisherEdinburgh DataShare
Temporal coverage1 Nov 2018 - 30 May 2020
Geographical coverageUganda,UG,Mubende District,Kampala District,UGANDA,Africa

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