Research output per year
Research output per year
Abstract
Rat embryonic stem cells exhibit basal levels of spontaneous differentiation in 2i+LIF (2iL) culture. Expression of a stem cell specific Rex1-EGFP knock-in reporter transgene in rat ESCs was used to isolate functionally distinct subsets of cells in rat ESC cultures, and determine their transcriptional profiles by single cell RNA sequencing.
Data Citation
Burdon, Tom; Meek, Stephen; Joshi, Anagha; Chandra, Tamir. (2019). Single cell transcriptional profiling of rat embryonic stem cells defined by Rex1-EGFP reporter expression, [dataset]. University of Edinburgh. Roslin Institute. https://doi.org/10.7488/ds/2639.
| Date made available | 1 Nov 2019 |
|---|---|
| Publisher | Edinburgh DataShare |
Research output
- 1 Article
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A stem cell reporter for investigating pluripotency and self-renewal in the rat.
Meek, S., Wei, J., Oh, T., Olavarrieta, J., Sutherland, L., Carlson, D. F., Salzano, A., Chandra, T., Joshi, A. & Burdon, T., 2 Jan 2020, (E-pub ahead of print) In: Stem Cell Reports.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Datasets
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Primary Dataset of Single cell transcriptional profiling of rat embryonic stem cells defined by Rex1-EGFP reporter expression
Burdon, T. (Creator), Meek, S. (Creator), Chandra, T. (Creator), Joshi, A. (Creator) & Simpson, C. (Data Manager), Edinburgh DataVault, 2020
DOI: 10.7488/078deee1-6e1e-4bae-a483-4ec093ec126f
Dataset