Abstract
Canine chondrocytes and osteoblasts were embedded in an agarose matrix and simultaneously stimulated with cytokines whilst being cyclically compressed. Both cell types were compressed for 4 hours at 1 Hz followed by a 24 hour recovery incubation. The chondrocytes were stimulated with 5 ng/mL of IL8 for the duration of compression, but removed for the recovery phase. Osteoblasts were stimulated with 0.5 ng/mL IL8 and 0.5 ng/mL IL1b for the duration of the compression and for the entirety of the 24 hour incubation step.
Data Citation
Johnson, Craig; Clements, Dylan. (2016). Stimulation of canine joint cells to model osteoarthritis, [dataset]. Roslin Institute, University of Edinburgh.
Date made available | 5 Aug 2016 |
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Publisher | Edinburgh DataShare |
Temporal coverage | 2016 - 2016 |