Methods
This dataset contains
-experimental data
-R code
associated with the manuscript: "Stochastic bacterial population dynamics restrict the establishment of antibiotic resistance from single cells". Please refer to the manuscript and its Supplementary Text for detailed methods.
This dataset contains experimental data and custom R code for likelihood-based model-fitting associated with the manuscript "Stochastic bacterial population dynamics restrict the establishment of antibiotic resistance from single cells". In particular, we estimate the per-cell establishment probability (i.e. probability that a single cell gives rise to a large population) of a resistant strain, in the presence of antibiotics at concentrations below its standard minimum inhibitory concentration. The experiments are conducted here with Pseudomonas aeruginosa, while the model and methods can be applied more generally.
Alexander, Helen K.; MacLean, R. Craig (2020), Data and code for: Stochastic bacterial population dynamics restrict the establishment of antibiotic resistance from single cells, v3, Dryad, Dataset, https://doi.org/10.5061/dryad.12jm63xtb
Date made available | 23 Jul 2020 |
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Publisher | Dryad |
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