Summary statistics from epigenome-wide association studies and meta-analysis comparing APOE ε4 and APOE ε2 allele carriers in Generation Scotland

These datasets contain full summary statistics for epigenome-wide association studies (EWASs) carried out using two methylation samples from the Generation Scotland: Scottish Family Health Study to investigate associations between blood-based DNA methylation and APOE ε4 vs. ε2 carrier status. The two samples were termed the "discovery" and "replication" samples and a meta-analysis of the EWAS results from the two samples was performed. These datasets are described fully in the associated preprint, which is available on bioRxiv (https://www.biorxiv.org/content/10.1101/815035v2.full).

Walker, Rosie; Vaher, Kadi; Bermingham, Mairead; Morris, Stewart; Bretherick, Andrew; Zeng, Yanni; Rawlik, Konrad; Amador, Carmen; Campbell, Archie; Haley, Chris; Hayward, Caroline; Porteous, David; McIntosh, Andrew; Marioni, Riccardo; Evans, Kathryn. (2020). Summary statistics from epigenome-wide association studies and meta-analysis comparing APOE ε4 and APOE ε2 allele carriers in Generation Scotland, [dataset]. The University of Edinburgh. https://doi.org/10.7488/ds/2948.