Supersaturation dependence of glycine polymorphism using laser-induced nucleation, sonocrystallization and nucleation by mechanical shock

Dataset

Abstract

The nucleation of glycine from aqueous supersaturated solution has been studied using nonphotochemical laser-induced nucleation (NPLIN), ultrasound (sonocrystallization), and mechanical shock of sample vials. It was found that at higher supersaturation, samples were more susceptible to nucleation and produced more of the γ-glycine polymorph. The results are described in terms of a mechanism common to all three nucleation methods, involving the induction of cavitation events and
pressure shockwaves. The switch in preference from α- to γ-glycine was observed to occur over a narrower range of supersaturation values for NPLIN. We attribute this to induction of cavitation events with higher energies, which result in higher localized pressures and supersaturations. Experiments on NPLIN using circularly versus linearly polarized light showed no evidence for binary polarization switching control of glycine polymorphism.

Data Citation

Alexander, Andrew; Liu, Yao; van den Berg, Mees. (2017). Supersaturation dependence of glycine polymorphism using laser-induced nucleation, sonocrystallization and nucleation by mechanical shock, [dataset]. University of Edinburgh, School of Chemistry. http://dx.doi.org/10.7488/ds/2096.
Date made available11 Jul 2017
PublisherEdinburgh DataShare

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