The functional enhancer repertoire of human embryonic stem cells

  • Tashin Barakat (MRC Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland., Erasmus University Medical Center) (Creator)
  • Florian Halbritter (Creator)
  • Man Zhang (Creator)
  • André F Rendeiro (Creator)
  • Elena Perenthaler (Creator)
  • Christoph Bock (Creator)
  • Ian Chambers (Creator)



Genome binding/occupancy profiling by high throughput sequencing


We combined Self-Transcribing Active Regulatory Region Sequencing (STARR-seq) with an enrichment step using chromatin immunoprecipitation in a massively parallel reporter assay. We applied this assay, termed ChIP-STARR-seq, to normal (primed) and naive human embryonic stem cells, building up a comprehensive catalogue of functional enhancers. For further details, please refer to the sub-series.

Data Citation

Barakat TS, Halbritter F, Zhang M, Rendeiro AF et al. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. National Center for Biotechnology Information (Gene Expression Omnibus).

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