The third International Stroke Trial (IST-3)

Peter Sandercock (Creator)
Joanna Wardlaw (Creator)
Richard Lindley (Creator)
Geoff Cohen (Creator)
William Whiteley (Creator)

Dataset

Abstract

The IST-3 trial is a large-scale randomised controlled trial of intravenous thrombolytic therapy with the drug Alteplase. The dataset includes a number of files describing the IST-3 dataset. The documentation files may be freely downloaded. The patient-level data are under embargo until the 25th of January 2021.

Data Citation

Sandercock, P; Wardlaw, J; Lindley, R; Cohen, G; Whiteley, W. (2016). The third International Stroke Trial (IST-3), 2000-2015 [dataset]. University of Edinburgh & Edinburgh Clinical Trials Unit. https://doi.org/10.7488/ds/1350

Date made available	25 Jan 2021
Publisher	Edinburgh DataShare
Temporal coverage	1 Jan 2000 - 31 Dec 2015
Geographical coverage	United Kingdom, Australia, Austria, Belgium, Canada, Italy, Norway, Poland, Portugal, Sweden, Switzerland

DOI
10.7488/ds/1350

7 Article
1 Literature review

Association between brain imaging signs, early and late outcomes, and response to intravenous alteplase after acute ischaemic stroke in the third International Stroke Trial (IST-3): secondary analysis of a randomised controlled trial
The IST-3 Collaborative Group , 1 May 2015, In: Lancet Neurology. 14, 5, p. 485-496 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Observer reliability of CT angiography in the assessment of acute ischaemic stroke: data from the Third International Stroke Trial
The IST-3 Collaborative Group , Jan 2015, In: Neuroradiology. 57, 1, p. 1-9 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Effect of Alteplase Within 6 Hours of Acute Ischemic Stroke on All-Cause Mortality (Third International Stroke Trial)
IST-3 Collaborative Grp, Whiteley, W. N., Thompson, D., Murray, G., Cohen, G., Lindley, R. I., Wardlaw, J. & Sandercock, P., Dec 2014, In: Stroke. 45, 12, p. 3612-3617 6 p.
Research output: Contribution to journal › Article › peer-review

International Stroke Trial-1 (version 2)
Sandercock, P. (Creator), Edinburgh DataShare, 2 Nov 2011
DOI: 10.7488/ds/104, https://doi.org/10.1186/1745-6215-12-101
Dataset
Updated bibliography for the IST-3 study
Sandercock, P. (Creator), Wardlaw, J. (Project Member) & Whiteley, W. (Project Member), Edinburgh DataShare, 28 Sept 2022
DOI: 10.7488/ds/3763
Dataset

The third International Stroke Trial (IST-3)

Abstract

Data Citation

DOI

Research output

Association between brain imaging signs, early and late outcomes, and response to intravenous alteplase after acute ischaemic stroke in the third International Stroke Trial (IST-3): secondary analysis of a randomised controlled trial

Observer reliability of CT angiography in the assessment of acute ischaemic stroke: data from the Third International Stroke Trial

Effect of Alteplase Within 6 Hours of Acute Ischemic Stroke on All-Cause Mortality (Third International Stroke Trial)

Datasets

International Stroke Trial-1 (version 2)

Updated bibliography for the IST-3 study

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