Wnt Pathway Analysis mapped gene-expression data

  • Victor Vendrell (Creator)
  • Patrick Frankel (Creator)
  • Martina Redmond (Creator)
  • Somantha Lillion-Connolly (Creator)
  • Chris Armit (Creator)
  • Bill Hill (Creator)
  • Shanmugasundaram Venkatarman (Creator)
  • Sun Yiwen (Creator)
  • Richard Baldock (Creator)
  • Duncan Davidson (Creator)
  • Jessica Maddock (Creator)
  • Paula Murphy (Creator)
  • Kristen Summerhurst (Creator)
  • Gareth Brady (Creator)

Dataset

Abstract

We provide a unique dataset of 3D mapped gene expression patterns that operate within a vital signalling system for normal development, openly available to the scientific community for further analysis. The associated published manuscript provides novel insight to the function of the Wnt pathway genes and demonstrates how the data can be used to build testable hypotheses. This dataset includes the spatial expression patterns of the whole Wnt and Fzd families of genes plus selected additional pathways genes mapped onto standard spatial reference embryos at three stages of mouse embryo development. These were selected as of the most critical times for organ development and are E9.5 (Theiler stage 15), E10.5 (Theiler stage 17) and E11.5 (theiler stage 19).

Data Citation

Murphy, Paula; Summerhurst, Kristen; Brady, Gareth; Vendrell, Victor; Frankel, Patrick; Redmond, Martina; Maddock, Jessica; Lillion-Connolly, Somantha; Armit, Chris; Hill, Bill; Venkatarman, Shanmugasundaram; Yiwen, Sun; Baldock, Richard; Davidson, Duncan. (2021). Wnt Pathway Analysis mapped gene-expression data, [dataset]. University of Edinburgh. IGMM. MRC Human Genetics Unit. https://doi.org/10.7488/ds/3141.
Date made available1 Nov 2022
PublisherEdinburgh DataShare

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