Centre for Clinical Brain Sciences

Search results

• Inhibitory synapse loss and accumulation of amyloid beta in inhibitory presynaptic terminals in Alzheimer’s disease - Kurucu et al

  Spires-Jones, T. (. (Creator), Edinburgh DataShare, 26 Jul 2021

  DOI: 10.7488/ds/3098, https://doi.org/10.1111/ene.15043

  Dataset

• Somatic Cell Nuclear Transfer (Cloning) Efficiency

  Wilmut, I. (Creator) & Paterson, L. A. (Creator), Edinburgh DataShare, Jul 2002

  DOI: 10.7488/ds/312, http://www.nature.com/nature/journal/v419/n6907/full/nature01079.html

  Dataset

• PREVENT Baseline Dataset - Baseline Dataset 2021

  Danso, S. (Creator), Ritchie, C. (Owner) & Muniz Terrera, G. (Researcher), Edinburgh DataVault, 2 Nov 2021

  DOI: 10.7488/6831068b-3fdd-432f-8578-6c90b0f90f3e

  Dataset

• Scottish Family Mental Health (SFMH) Study Dataset

  Cooper, A. (Creator), Blackwood, D. (Creator), Lawrie, S. (Creator), McIntosh, A. (Creator), Romaniuk, L. (Creator), Semple, S. (Creator), Duff, B. (Creator) & Whalley, H. (Creator), Edinburgh DataVault, 10 Oct 2023

  DOI: 10.7488/7f08e5f1-b300-4a32-bd18-ef511f82c390

  Dataset

• Comparative profiling of the synaptic proteome from Alzheimer’s disease patients with focus on the APOE genotype - proteomics dataset

  Spires-Jones, T. (Creator) & Wishart, T. (Creator), PRIDE database hosted by European Bioinformatics Institute, EBI, May 2020

  https://www.ebi.ac.uk/pride/archive/projects/PXD013753

  Dataset

• Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer’s disease

  Catalano, S. M. (Creator), Dando, O. (Creator), Hamby, M. E. (Creator), Izzo, N. J. (Creator), Smith, C. (Creator), Spires-Jones, T. (Creator), Colom Cadena, M. (Creator), Toombs, J. (Creator), Simzer, E. M. (Creator), Tulloch, J. (Creator), Jackson, R. (Creator), Catterson, J. (Creator), Rose, J. (Creator), Waybright, L. (Creator), Caggiano, A. O. (Creator), Davies, C. (Creator), Hooley, M. (Creator), Dunnett, S. (Creator), Tempelaar, R. (Creator) & Tzioras, M. (Creator), Edinburgh DataShare, 9 Jan 2024

  DOI: 10.7488/ds/7664, https://www.biorxiv.org/content/10.1101/2021.02.01.428238v2

  Dataset

• Archiving and Sharing Functional MRI data 

  Pernet, C. (Creator), Edinburgh DataShare, 27 Jul 2015

  DOI: 10.7488/ds/283

  Dataset

• Colour vision deficiency and perfusion brain scans

  Kyaw, K. L. S. (Creator), Gentry, R. (Creator), Barber, M. (Creator) & Mair, G. (Creator), Edinburgh DataShare, 14 Jun 2024

  DOI: 10.7488/ds/7752

  Dataset

• SUPPLEMENTAL MATERIAL: Effect of IV alteplase on the ischemic brain lesion Neurology 2018 

  Mair, G. (Creator), Edinburgh DataShare, 22 Jun 2018

  DOI: 10.7488/ds/2367

  Dataset

• Gabapentin for the Management of Chronic Pelvic Pain in Women (GaPP1)

  Horne, A. (Creator), Vincent, K. (Creator) & Pernet, C. R. (Creator), Edinburgh DataShare, 13 Aug 2018

  DOI: 10.7488/ds/2411

  Dataset

• The potential of eye-tracking as a sensitive measure of behavioural change in response to intervention: processed data set

  Hampton, S. (Creator) & Fletcher-Watson, S. (Creator), Edinburgh DataShare, 2 Oct 2018

  DOI: 10.7488/ds/2450, https://www.nature.com/articles/s41598-018-32444-9

  Dataset

• The Edinburgh Computed tomography and genetic diagnostic criteria for lobar intracerebral haemorrhage associated with cerebral amyloid angiopathy: model development, internal validation and diagnostic test accuracy study

  Rodrigues, M. (Creator) & Salman, R. (Creator), Edinburgh DataShare, 13 Oct 2022

  DOI: 10.7488/ds/2230

  Dataset

• Mouse Lifespan Synaptome Atlas dataset

  Cizeron, M. (Creator), Qiu, R. (Creator), Koniaris, B. (Creator), Gokhale, R. (Creator), Komiyama, N. (Creator), Fransen, E. (Creator) & Grant, S. (Creator), Edinburgh DataShare, 18 Nov 2019

  DOI: 10.7488/ds/2796, https://doi.org/10.1101/838458

  Dataset

• Synaptome data with individual synapse parameters, types and subtypes across the 5 coronal mouse brain section

  Grant, S. (Creator), Koniaris, B. (Creator) & Qiu, R. (Creator), Edinburgh DataShare, 20 Jun 2019

  DOI: 10.7488/ds/2366

  Dataset

• GOLD Depression Study

  Laughton, B. (Creator), Glashoff, R. (Creator), Naidoo, S. (Creator), Robertson, F. (Creator), Mudra Rakshasa-Loots, A. (Creator) & Meintjes, E. (Creator), Edinburgh DataShare, 25 Jan 2024

  DOI: 10.7488/ds/7507

  Dataset

• The Edinburgh diagnostic criteria for lobar intracerebral haemorrhage associated with moderate/severe cerebral amyloid angiopathy

  Salman, R. (Creator) & Rodrigues, M. (Creator), Edinburgh DataShare, 29 Nov 2017

  DOI: 10.7488/ds/2262

  Dataset

• LIMO EEG v1.5

  Pernet, C. R. (Creator), Rousselet, G. A. (Creator), Chauveau, N. (Creator) & Gaspar, C. (Creator), Edinburgh DataShare, 17 Nov 2016

  DOI: 10.7488/ds/1557

  Dataset

• Human tau increases amyloid beta plaque size but not amyloid beta-mediated synapse loss in a novel mouse model of Alzheimer’s disease: Data set from Jackson et al 2016 EJN

  Spires-Jones, T. (Creator) & Jackson, R. (Creator), Edinburgh DataShare, 28 Oct 2016

  DOI: 10.7488/ds/1507

  Dataset

• Structural, functional and metabolic brain differences between groups with opposite gender identity and sexual orientation. A systematic review on the neuroimaging literature up to 2018

  Frigerio, A. (Creator), Ballerini, L. (Creator) & Valdes Hernandez, M. (Creator), Edinburgh DataShare, 13 Aug 2018

  DOI: 10.7488/ds/2412

  Dataset

• Human Brain Atlases across the lifespan – Anatomical Segmentations

  Valdes Hernandez, M. (Creator), Edinburgh DataShare, 7 May 2021

  DOI: 10.7488/ds/3029

  Dataset

• Images from paper: Synaptic resilience is associated with maintained cognition during ageing

  King, D. (Creator) & Spires-Jones, T. (Owner), Edinburgh DataVault, 26 Oct 2022

  DOI: 10.7488/b9dcf607-1339-4127-a3c0-263ce9f3d164

  Dataset

• Synapse loss in the prefrontal cortex is associated with cognitive decline in amyotrophic lateral sclerosis - Array tomography data and Analysis macros

  Spires-Jones, T. (Creator) & Henstridge, C. (Creator), Edinburgh DataShare, 18 Dec 2017

  DOI: 10.7488/ds/2269, https://datashare.is.ed.ac.uk/handle/10283/2974 and one more link, https://datashare.is.ed.ac.uk/handle/10283/2975 (show fewer)

  Dataset

• Supplemental materials: ALS-specific cognitive and behavior changes associated with advancing disease stage in ALS

  Crockford, C. (Creator) & Abrahams, S. (Creator), Edinburgh DataShare, 18 Sept 2018

  DOI: 10.7488/ds/2422

  Dataset

• Magnetisation transfer saturation (MTsat) processing

  York, B. (Creator), Thrippleton, M. (Creator) & Waldman, A. (Creator), Edinburgh DataShare, 17 Dec 2020

  DOI: 10.7488/ds/2965

  Dataset

• Metrics for quality control of results from super-resolution machine-learning algorithms – Data extracted from publications in the period 2017- May 2021

  Castorina, L. V. (Creator), Li, B. M. (Creator), Storkey, A. (Creator) & Valdes Hernandez, M. (Creator), Edinburgh DataShare, 24 Jun 2021

  DOI: 10.7488/ds/3062

  Dataset

• SV2A is expressed in subpopulations of mouse and human synapses

  Qiu, Z. (Creator), Notman, B. (Creator), Smith, C. (Creator), Grant, S. (Creator), Tavares, A. (Creator) & Wong, T. (Creator), Edinburgh DataShare, 13 Feb 2025

  DOI: 10.7488/ds/7865, https://doi.org/10.1101/2024.07.15.603608

  Dataset

• INSIDE-HIV: imaging neuroinflammation in severe and persistent depression in people with HIV DataVault 2024

  Mudra Rakshasa-Loots, A. (Creator) & Vera, J. (Creator), Edinburgh DataVault, 5 Dec 2024

  DOI: 10.7488/5d6256a4-2132-400d-84f8-f6445cc624f8

  Dataset

• lentiviral mediated apoE4 transduction in primary neuronal culture

  Wishart, T. (Creator), Edinburgh DataShare, 4 Mar 2025

  DOI: 10.7488/ds/2919

  Dataset

• Mix and Match: Mono-substituted Hydrocarbon Diastereomer Combinations Reveal Stapled Peptides with High Structural Fidelity

  McWhinnie, F. (Creator), Sepp, K. (Creator), Kunath, T. (Creator), Houston, D. (Creator), Hupp, T. (Creator) & Hulme, A. (Creator), Edinburgh DataShare, 22 Dec 2017

  DOI: 10.7488/ds/2276

  Dataset

• MATLAB-based framework for simulating DCE-MRI of subtle blood-brain barrier breakdown

  Manning, C. (Creator) & Thrippleton, M. (Creator), Edinburgh DataShare, 9 Mar 2021

  DOI: 10.7488/ds/2997

  Dataset

• Systematic Review and Meta-Analysis on the Impact of Polycyclic Aromatic Hydrocarbons Exposure in Cognitive Function and Neurodegeneration in Humans

  Humphreys, J. (Creator) & Valdes Hernandez, M. (Creator), Edinburgh DataShare, 6 May 2021

  DOI: 10.7488/ds/3031, https://www.preprints.org/manuscript/202105.0692/v1

  Dataset

• SAIL dementia e-cohort (SAIL-DeC)

  Gallacher, J. (Creator), Lyons, R. A. (Creator), Sudlow, C. (Creator), Orton, C. (Creator), Wilkinson, T. (Creator), Schnier, C. (Creator), Akbari, A. (Creator) & Sleegers, K. (Creator), Edinburgh DataShare, 26 Mar 2019

  DOI: 10.7488/ds/2505

  Dataset

• A synapse proteome resource for mouse brain regions

  Roy, M. (Creator), Sorokina, O. (Creator), McLean, C. (Creator), Silvia, T.-G. (Creator), DeFelipe, J. (Creator), Armstrong, J. D. (Creator) & Grant, S. (Creator), Edinburgh DataShare, 2 Aug 2018

  DOI: 10.7488/ds/2399

  Dataset

• Charting the Impact of Bilingualism for Autistic and Non-Autistic Children

  Montgomery, L. (Creator), Davis, R. (Creator), Rabagliati, H. (Creator), Sorace, A. (Creator) & Fletcher-Watson, S. (Creator), Edinburgh DataShare, 15 Jul 2021

  DOI: 10.7488/ds/3094

  Dataset

• 3 T BOLD CVR data from healthy volunteers suitable for within-day repeatability analyses

  Sleight, E. (Creator), Murphy, M. (Creator), Mitchell, M. (Creator) & Thrippleton, M. (Creator), Edinburgh DataShare, 5 Jul 2024

  DOI: 10.7488/ds/3492

  Dataset

• RESTART | planned secondary analyses

  Salman, R. (Creator), Edinburgh DataShare, 22 May 2019

  DOI: 10.7488/ds/2551

  Dataset

• Associations between alcohol use and accelerated biological ageing

  Wootton, R. E. (Creator), Clarke, T.-K. (Creator), Cox, S. (Creator), Bostrand, S. (Creator), Vaher, K. (Creator), De Nooij, L. (Creator), Harris, M. A. (Creator), Cole, J. H. (Creator), Marioni, R. (Creator), Mccartney, D. (Creator), Walker, R. (Creator), McIntosh, A. (Creator), Evans, K. (Creator) & Whalley, H. (Creator), Edinburgh DataShare, 24 Nov 2020

  DOI: 10.7488/ds/2956

  Dataset

• Brain Templates across the lifespan – Confounding and artefactual regions in PVS segmentation

  Valdes Hernandez, M. (Creator), Edinburgh DataShare, 5 Jun 2024

  DOI: 10.7488/ds/7744

  Dataset

• A Celebration of Scottish Health Cohort Studies: Participants' attitudes towards data research

  Beange, I. (Creator), McIntosh, A. (Creator), Kirkham, E. (Creator), Fletcher-Watson, S. (Creator), Lawrie, S. (Creator), Batty, G. D. (Creator), Boardman, J. (Creator), Black, C. (Creator) & Porteous, D. (Creator), Edinburgh DataShare, 16 Dec 2019

  DOI: 10.7488/ds/2728

  Dataset

• GWAS summary stats for meta-analysis of epigenetic age acceleration - Gibson et al, (2019)

  Clarke, T. (Creator), McIntosh, A. (Creator) & Marioni, R. (Creator), Edinburgh DataShare, 30 Nov 2019

  DOI: 10.7488/ds/2631, https://doi.org/10.1101/585299

  Dataset

• Methylome-wide association study of early life stressors and adult mental health

  Howard, D. (Creator), Edinburgh DataShare, 7 Sept 2021

  DOI: 10.7488/ds/3126

  Dataset

• Proteomic analysis of postsynaptic proteins in regions of the human neocortex

  Grant, S. (Creator), Roy, M. (Creator), Sorokina, O. (Creator), Skene, N. (Creator), Simonnet, C. (Creator), Smith, C. (Creator) & Armstrong, J. D. (Creator), Edinburgh DataShare, 1 Sept 2017

  DOI: 10.7488/ds/2789

  Dataset

• Data extraction and analysis of the systematic search on gender differences on brain MRI structures and connectivity

  Martin, S. (Creator) & Valdes Hernandez, M. (Creator), Edinburgh DataShare, 2 Jun 2017

  DOI: 10.7488/ds/2053

  Dataset

• Research Plan - The effect of APOE genotype on microglial-mediated synapse loss in AD

  Spires-Jones, T. (Creator) & Tzioras, M. (Creator), Edinburgh DataShare, 5 Apr 2018

  DOI: 10.7488/ds/2335

  Dataset

• Proteomics datasets from Shorrock et al (UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy)

  Gillingwater, T. (Creator), Edinburgh DataShare, 8 Aug 2018

  DOI: 10.7488/ds/2405

  Dataset

• 'Harnessing the little white cells': tracing practices of immunity in cancer, 2020 – 2024.

  Pickersgill, M. (Owner) & Swallow, J. (Creator), Edinburgh DataVault, 16 Aug 2024

  DOI: 10.7488/e04cf9ef-e67c-46ee-91e9-725c393d79e9

  Dataset

• Connectomic analysis of the mouse fourth deep lumbrical muscle connectome

  Hirst, T. C. (Creator) & Ribchester, R. (Creator), Edinburgh DataShare, 30 Jun 2017

  http://datashare.is.ed.ac.uk/handle/10283/2657

  Dataset

• Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer’s disease - Data from 2017 Publication

  Spires-Jones, T. (Creator) & Pickett, E. (Creator), Edinburgh DataShare, 6 Feb 2017

  DOI: 10.7488/ds/1706, http://onlinelibrary.wiley.com/doi/10.1002/syn.21965/full

  Dataset

• NPQIP final analysis set

  MacLeod, M. (Creator), Figshare, 12 Sept 2017

  DOI: 10.6084/m9.figshare.5375275.v1

  Dataset

• INSIDE-HIV: imaging neuroinflammation in severe and persistent depression in people with HIV - DataShare dataset for INSIDE - HIV study

  Ronen, I. (Creator), Diteko, G. (Creator), Dowell, N. G. (Creator), Vera, J. (Creator) & Mudra Rakshasa-Loots, A. (Creator), Edinburgh DataShare, 1 Apr 2025

  DOI: 10.7488/ds/7843

  Dataset