Centre for Clinical Brain Sciences

Projects

Projects per year 1996 2007 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2028

• 10 Not started
• 51 Active
• 524 Finished

Projects per year

Search results

• Finished

  Developing pathways within the UK for screening of cognitive and behaviour change in MND

  Abrahams, S.

  UK-based charities

  1/09/16 → 31/08/19

  Project: Research

  • Motor Neuron Disease 100%
  • Amyotrophic Lateral Sclerosis 42%
  • Ambulatory Care Facilities 39%
  • Cognition 31%
  • Interviews 26%

• Dementias Platform UK Stem Cell Partnership

  Chandran, S.

  MRC

  1/08/16 → 31/01/21

  Project: Research

  • Organoids 100%
  • Neuroimaging 69%
  • Chromosomes 60%
  • Cell Proliferation 25%
  • Cell Division 18%

• Edmond J. Safra Fellowship in Movement Disorders, Michael J. Fox Foundation

  Breen, D.

  1/08/16 → 31/07/18

  Project: Project from a former institution

• A small molecule screen to identify modulators of brain repair

  Herrgen, L.

  UK-based charities

  1/08/16 → 31/01/17

  Project: Research

• Understanding and Exploiting the Therapeutic Time Window in Mouse Models of SMA

  Murray, L.

  Other

  1/08/16 → 31/01/20

  Project: Research

• Start or STop Anticoagulants Randomised Trial (SoSTART) after spontaneous intracranial haemorrhage

  Salman, R.

  UK-based charities

  1/08/16 → 31/07/18

  Project: Research

• Mechanisms of organophosphorus pesticide toxicity at neuromuscular junctions

  Ribchester, R.

  UK-based charities

  18/07/16 → 11/09/16

  Project: Research

• Multilingualism: Empowering Individuals, Transforming Societies (MEITS)

  Bak, T.

  AHRC

  1/07/16 → 30/06/20

  Project: Research

  • Bilingualism 100%
  • multilingualism 87%
  • Multilingualism 66%
  • speech disorder 50%
  • stroke 48%

• The Cognitive Health in Ageing Register: Investigational, Observational, and Trial Studies in Dementia Research (CHARIOT): Prospective Readiness cOhort Study (PRO)

  Ritchie, C.

  Other

  1/06/16 → 31/07/20

  Project: Research

• Evaluation of computational methods for estimating the cortical stroke lesion evolution from magnetic resonance images.

  Valdes Hernandez, M.

  UK-based charities

  31/05/16 → 25/07/16

  Project: Research

• BRIDGET - BRain Imaging, cognition, Dementia and next generation GEenomics

  Deary, I., Bastin, M., Luciano, M., Prendergast, J. & Wardlaw, J.

  MRC

  1/05/16 → 31/10/19

  Project: Research

  • Diffusion Tensor Imaging 100%
  • Longevity 79%
  • Single Nucleotide Polymorphism 74%
  • Water 73%
  • Nucleotides 71%

• The Disconnected Mind Phase 3

  Wardlaw, J.

  UK-based charities

  1/04/16 → 30/09/20

  Project: Research

  • Parturition 100%
  • White Matter 65%
  • DNA Methylation 51%
  • Cognitive Aging 48%
  • Genome-Wide Association Study 46%

• VOICEBANKING PILOT PROJECT

  Chandran, S.

  UK central government bodies/local authorities, health and hospital authorities

  1/04/16 → 28/02/18

  Project: Research

• Three-dimensional modelling of endothelial cell dysfunction in cerebral small vessel disease

  Williams, A.

  UK-based charities

  1/04/16 → 28/02/17

  Project: Research

  • Oligodendroglia 100%
  • Cell Communication 85%
  • Endothelial Cells 67%
  • White Matter 62%
  • Cerebral Small Vessel Diseases 33%

• Enhanced Control of Hypertension and Thrombolysis Stroke Study (STAY ENCHANTED)

  Wardlaw, J.

  Other

  1/04/16 → 1/10/18

  Project: Research

  • Stroke 100%
  • Blood Pressure 93%
  • Tissue Plasminogen Activator 52%
  • Guidelines 41%
  • Intracranial Hemorrhages 27%

• Feasibility study of obtaining high-resolution spectroscopy images using data fusion techniques

  Valdes Hernandez, M. & Ozturk-Isik, E.

  UK-based charities

  15/03/16 → 14/03/17

  Project: Research

  • Magnetic resonance 100%
  • Convolutional neural networks 87%
  • Magnetic Resonance Spectroscopy 81%
  • Imaging techniques 73%
  • Education 60%

• Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST 2)

  Wardlaw, J.

  UK-based charities

  1/02/16 → 30/11/22

  Project: Research

• DFG CRC167: Development, function and potential of myeloid cells in the CNS

  Priller, J.

  1/01/16 → 31/12/20

  Project: Project from a former institution

• Characterisation of a CRISPR-engineered rat model of Parkinson’s disease

  Tavares, A. & Kunath, T.

  1/01/16 → 31/08/16

  Project: University Awarded Project Funding

  • DNA Methylation 100%
  • RNA Interference 97%
  • Epigenomics 88%
  • Cytosine 72%
  • RNA 70%

• Understanding and Exploiting the Therapeutic Time Window in Mouse Models of Spinal Muscular Atrophy

  Murray, L.

  UK-based charities

  1/01/16 → 31/12/17

  Project: Research

• Accuracy, pattern and possible underlying factors of brain microbleeds progression on older adults with absence or mild presence of vascular pathology

  Valdes Hernandez, M.

  1/01/16 → 31/03/16

  Project: University Awarded Project Funding

  • Pathology 100%
  • Blood Vessels 93%
  • Magnetic Resonance 82%
  • Brain 77%
  • Cholesterol 72%

• SVDs-at-target: Small vessel diseases in a mechanistic perspective: Targets for Intervention Affected pathways and mechanistic exploitation for prevention of stroke and dementia

  Wardlaw, J.

  EU government bodies

  1/01/16 → 31/12/21

  Project: Research

  • White Matter 100%
  • Stroke 86%
  • Cerebral Small Vessel Diseases 71%
  • Brain 45%
  • Lacunar Stroke 44%

• Understanding how spinal neural circuits generate flexible motor output

  Zhang, H.

  BBSRC

  1/01/16 → 22/07/19

  Project: Research

  • interneurons 100%
  • Cord 97%
  • Xenopus 84%
  • Interneurons 84%
  • tadpoles 84%

• The UK Spinal Muscular Atrophy Consortium

  Gillingwater, T. & Becker, C.

  Other

  1/01/16 → 3/03/20

  Project: Research

• DPUK-IMAGING INFORMATICS

  Gourley, C., Job, D. & Wardlaw, J.

  Other

  1/01/16 → 8/07/17

  Project: Research

• Small vessel disease pathophysiology: human postmortem brain tissue study with clinical radiological pathological correlation - Fellowship for Catherine Humphreys

  Wardlaw, J. & Smith, C.

  UK-based charities

  1/12/15 → 31/12/19

  Project: Research

• ECAT (203699) Multi-modality imaging assessment of cerebral small vessel disease biomarkers after stroke due to spontaneous intracerebral haemorrhage

  Wardlaw, J. & Salman, R.

  UK-based charities

  1/12/15 → 30/11/18

  Project: Research

  • Cerebral Amyloid Angiopathy 100%
  • Cerebral Hemorrhage 76%
  • systematic review 45%
  • meta-analysis 40%
  • Routine Diagnostic Tests 38%

• Glial cell involvement in spinal motor control: cheering from the side-lines or part of the team?

  Chandran, S.

  Other

  15/11/15 → 14/11/18

  Project: Research

• FutureMS: Predicting disease activity in people with newly diagnosed MS based on baseline clinical, imaging and genetic profiles

  Chandran, S.

  UK central government bodies/local authorities, health and hospital authorities

  1/10/15 → 31/12/21

  Project: Research

• Preventing cognitive decline and dementia from cerebral microvascular disease

  Wardlaw, J.

  UK-based charities

  1/10/15 → 31/07/18

  Project: Research

  • isosorbide-5-mononitrate 100%
  • Cerebral Small Vessel Diseases 94%
  • Cilostazol 94%
  • Lacunar Stroke 85%
  • Dementia 53%

• Row Fogo Charitable Trust Funds

  Wardlaw, J.

  UK-based charities

  1/10/15 → 30/09/18

  Project: Research

  • White Matter 100%
  • Cerebral Small Vessel Diseases 80%
  • Stroke 47%
  • Brain 42%
  • Aptitude 38%

• Development of confocal endomicroscopy for MND Research

  Ribchester, R., Gillingwater, T. & Skehel, P.

  UK-based charities

  1/10/15 → 6/07/19

  Project: Research

  • Neuromuscular 100%
  • Neuromuscular Junction 83%
  • Synapses 65%
  • Strength 18%
  • Population 14%

• FUTURE-MND

  Chandran, S.

  UK-based charities

  1/10/15 → 31/03/19

  Project: Research

• Animal or In-Vitro

  Mahad, D.

  Non-EU industry, commerce and public corporations

  1/09/15 → 31/08/16

  Project: Research

• The Incidence and Importance of Motor Unit Sprouting in Mouse Models of Spinal Muscular Atrophy

  Murray, L.

  UK-based charities

  1/09/15 → 31/10/16

  Project: Research

• Sleep Research Assistant

  Riha, R.

  UK-based charities

  1/09/15 → 31/08/16

  Project: Research

• Developing an intervention for treating anxiety post-stroke

  Chun, Y., Carson, A., Whiteley, W., Mead, G. & Dennis, M.

  1/09/15 → 31/08/18

  Project: Awarded Facility Time

  • Anxiety 100%
  • Stroke 47%
  • Observational Studies 18%
  • Interviews 15%
  • Clinical Trials 15%

• How do peripheral and central vascular markers relate to cognitive decline? (Project 8)

  Deary, I.

  UK-based charities

  10/08/15 → 31/08/17

  Project: Research

  • White Matter 100%
  • Brain 89%
  • Intelligence 77%
  • dementia 73%
  • brain 69%

• Equipment Grant - MR Scanner

  Wardlaw, J.

  UK-based charities

  1/08/15 → 31/07/20

  Project: Research

• Fellowship for Danielle Leighton: Population based genotype-phenotype correlation to stratify incident cases of patients with motor neurone disease in Scotland from 2015-2017

  Leighton, D., Chandran, S. & Pal, S.

  UK central government bodies/local authorities, health and hospital authorities

  1/08/15 → 31/07/18

  Project: Research

• ISS: flutemetamol for the ante mortem recognition of intracerebral haemorrhage due to cerebral amyloid angiopathy

  Salman, R.

  UK industry, commerce and public corporations

  1/08/15 → 31/10/22

  Project: Research

• TICH2 trial MRI sub-study co-applicant

  Salman, R.

  30/06/15 → 30/06/18

  Project: Research Collaboration with external organisation

  • Tranexamic Acid 100%
  • Organized Financing 89%
  • Cerebral Hemorrhage 81%
  • Randomized Controlled Trials 51%
  • Heart 49%

• Senior Clinical Lectureship: A platform for patient focused trials to prevent cerebral small vessel disease

  Doubal, F.

  UK-based charities

  1/06/15 → 31/05/21

  Project: Research

  • isosorbide-5-mononitrate 100%
  • Cerebral Small Vessel Diseases 94%
  • Cilostazol 94%
  • Lacunar Stroke 93%
  • Stroke 74%

• VIS-NET: Vision Network

  Underwood, I., Dhillon, B. & Nuthmann, A.

  1/06/15 → 31/12/16

  Project: University Awarded Project Funding

  • Ophthalmology 100%
  • Display devices 49%

• Understanding and Maximising the Therapeutic Time Window in Mouse Models of SMA

  Murray, L.

  Other

  1/05/15 → 31/12/17

  Project: Research

• Brain imaging and cognitive ageing in the Lothian Birth Cohort 1936: III

  Wardlaw, J., Bastin, M. & Deary, I.

  MRC

  1/05/15 → 30/04/19

  Project: Research

  • White Matter 100%
  • Parturition 93%
  • Brain 88%
  • Aptitude 63%
  • DNA Methylation 51%

• Right-2 Imaging Resources - Rapid Intervention With Glyceryl Trinitrate In Hypertensive Stroke Trial-2 (Right-2)

  Wardlaw, J.

  Other

  1/05/15 → 31/10/18

  Project: Research

  • isosorbide-5-mononitrate 100%
  • Cilostazol 94%
  • Lacunar Stroke 85%
  • Ambulances 77%
  • Nitroglycerin 73%

• TEST Multi-modal retinal biomarkers for vascular dementia: developing enabling image analysis tools

  Wardlaw, J.

  Other

  30/04/15 → 28/08/18

  Project: Research

  • Microvessels 100%
  • Independent Living 90%
  • dementia 87%
  • Dementia 85%
  • Retinal Vessels 65%

• Quantification of vascular disease burden to stratify dementia for diagnosis and care management

  Valdes Hernandez, M. & Wardlaw, J.

  1/04/15 → 31/03/17

  Project: Research Collaboration with external organisation

  • Pathology 100%
  • White Matter 87%
  • Brain 61%
  • Magnetic resonance imaging 52%
  • Magnetic Resonance Spectroscopy 49%

• Brain Slice project

  Williams, A.

  UK industry, commerce and public corporations

  1/04/15 → 31/03/17

  Project: Research