Centre for Clinical Brain Sciences

Projects

Projects per year 1996 2007 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2028

• 10 Not started
• 51 Active
• 524 Finished

Projects per year

Search results

• Finished

  Quantification of vascular disease burden to stratify dementia for diagnosis and care management

  Wardlaw, J.

  UK central government bodies/local authorities, health and hospital authorities

  1/04/15 → 30/06/17

  Project: Research

  • Leukoaraiosis 100%
  • Metadata 64%
  • Brain 64%
  • Brain Injuries 63%
  • Stroke 55%

• Brain Slice project

  Williams, A.

  UK industry, commerce and public corporations

  1/04/15 → 31/03/17

  Project: Research

• UKDP: Integrated DEmentiA research environment (IDEA)

  van Beek, E., Chandran, S., Deary, I., Ffrench-Constant, C. & Wardlaw, J.

  MRC

  1/04/15 → 30/06/16

  Project: Research

  • dementia 100%
  • Reproducibility of Results 88%
  • Dementia 83%
  • incident 81%
  • Psychometrics 69%

• Modelling sub-clinical vCJD infection in the UK population

  Diack, A. & Manson, J.

  UK central government bodies/local authorities, health and hospital authorities

  1/04/15 → 31/03/19

  Project: Research

• Pragmatic Ischaemic Stroke Thrombectomy Evaluation

  Wardlaw, J.

  Other

  1/04/15 → 29/02/16

  Project: Research

• PreMDD: Predicting major depressive disorder

  Porteous, D., Nicodemus, K., Agakov, F., McKeigue, P., Campbell, A., Bermingham, M., Munoz, D. U., McIntosh, A. & Marriage, H. M.

  1/04/15 → 30/09/15

  Project: University Awarded Project Funding

  • Scotland 100%
  • Machine Learning 97%
  • Major Depressive Disorder 81%
  • Family Health 45%
  • Demography 29%

• Identification of selective and potent inhibitors of the Semaphorin 3A Receptor Neuropilin-1 interaction on oligodendrocyte precursor cells to promote remyelination in Multiple Sclerosis

  Williams, A.

  Non-EU industry, commerce and public corporations

  1/03/15 → 28/02/17

  Project: Research

• What are the mechanisms by which myelination in theCNS is established and refined?

  Ffrench-Constant, C.

  UK-based charities

  1/03/15 → 30/11/20

  Project: Research

  • Myelin Sheath 100%
  • Neuroepithelial Cells 93%
  • Endothelins 74%
  • Oligodendroglia 71%
  • Axons 56%

• Understanding the role of altered ubiquitin homeostasis in motor neuron diseases

  Gillingwater, T. & Groen, E.

  1/03/15 → 31/08/19

  Project: Research

  • Spinal Muscular Atrophy 100%
  • Motor Neurons 48%
  • muscular atrophy 14%
  • Ubiquitin 14%
  • Proteostasis 13%

• PPLS Pilot Scheme: Bilingualism Study

  Bak, T.

  1/03/15 → 31/08/15

  Project: University Awarded Project Funding

  • Bilingualism 100%
  • Edinburgh 89%
  • multilingualism 87%
  • Singapore 77%
  • Language Switching 35%

• Advanced neuroimaging for canine brain tumours £4000

  Rzechorzek, N.

  7/02/15 → 7/02/16

  Project: University Awarded Project Funding

• Using electrophysiology to investigate the causes of severe mental disorders

  Marwick, K.

  2/02/15 → 3/08/16

  Project: MVM - (non-funded) undergraduate research project

  • Electrophysiology 100%
  • Mental Disorders 72%
  • Neurosciences 47%
  • Touch 44%
  • Autistic Disorder 44%

• An automated in vivo screening platform for the UK zebrafish research community

  Becker, C., Lyons, D. & Patton (don't use), E.

  BBSRC

  15/01/15 → 14/01/16

  Project: Research

• EPAD: European Prevention of Alzheimers Dementia Consortium - Management Budget

  Ritchie, C.

  EU government bodies

  1/01/15 → 31/10/20

  Project: Research

• Development of a high-throughput assay for research in myelin sheath formation

  Ffrench-Constant, C.

  BBSRC

  1/01/15 → 1/01/15

  Project: Research

• EPAD: European Prevention of Alzheimers Dementia Consortium - RTD Budget

  Ritchie, C.

  EU government bodies

  1/01/15 → 31/10/20

  Project: Research

• Progression pattern of brain mineral deposition as a differential indicator of cognitive decline

  Valdes Hernandez, M. & Clayson, L.

  1/01/15 → 31/03/15

  Project: University Awarded Project Funding

  • Magnetic Resonance 100%
  • Minerals 93%
  • Cholesterol 86%
  • Basal Ganglia 78%
  • Cognitive Dysfunction 63%

• Magnetic Resonance Imaging of Lifecourse Influences on Brain Health and Disease (Biomedical Resource/Multi-User Equipment/Technology Development Grant)

  Wardlaw, J., Boardman, J., Marshall, I., McIntosh, A. & Salman, R.

  UK-based charities

  1/01/15 → 31/12/19

  Project: Research

• EPAD: European Prevention Of Alzheimer's Dementia Consortium (Janssen - Medavante Subcontract)

  McTeir, B., Manson, J. & Ritchie, C.

  EU government bodies

  1/01/15 → 31/10/20

  Project: Research

  • Patient Reported Outcome Measures 100%
  • Alzheimer Disease 93%
  • Health Care Outcome Assessment 79%
  • Clinical Trials 78%
  • Patient Preference 67%

• Optogenetic oligodendrocyte ablation to produce focal CNS demyelination in slice cultures

  Williams, A.

  UK-based charities

  1/01/15 → 31/12/15

  Project: Research

• Textural Characterisation on Regions of Interest: A useful Tool for the Study of Small Vessel Disease

  Valdes Hernandez, M. & Viksne, L.

  1/01/15 → 31/03/15

  Project: University Awarded Project Funding

  File

  • honor 100%
  • Stroke 32%
  • Entropy 28%
  • Brain 23%
  • White Matter 21%

• EPAD: European Prevention Of Alzheimer's Dementia Consortium (Janssen)

  Wardlaw, J.

  EU government bodies

  1/01/15 → 31/10/20

  Project: Research

• Visualising the brain iPad App

  Wardlaw, J.

  UK-based charities

  1/12/14 → 31/03/15

  Project: Research

• Brain Imaging in Normal Subjects (BraINS): a searchable living brain image bank to improve brain scan reporting and diagnosis of pathological ageing

  Wardlaw, J. & Shenkin, S.

  UK-based charities

  25/11/14 → 24/11/15

  Project: Research

  • Atlases 100%
  • Brain 91%
  • Neuroimaging 84%
  • Magnetic Resonance Spectroscopy 78%
  • Pathology 58%

• Identifying and protecting vulnerable motor neurons in spinal muscular atrophy (SMA)

  Gillingwater, T. & Becker, C.

  UK-based charities

  24/11/14 → 23/11/16

  Project: Research

  • Spinal Muscular Atrophy 100%
  • muscular atrophy 55%
  • bioenergetics 49%
  • Motor Neurons 47%
  • motor neurons 44%

• Investigating the shared genetic basis of major depressive disorder (MDD) and type 2 diabetes (T2D).

  Clarke, T. & McIntosh, A.

  17/11/14 → 7/11/17

  Project: MVM - (non-funded) undergraduate research project

  • Major Depressive Disorder 100%
  • Dissection 52%
  • Schizophrenia 49%
  • Major Depressive Disorder 2 46%
  • Type 2 Diabetes Mellitus 45%

• SynthSys-Mammalian: Edinburgh Mammalian Synthetic Biology Research Centre

  Pollard, S. & Ffrench-Constant, C.

  BBSRC

  14/11/14 → 31/03/22

  Project: Research

  • Transcription Activator-Like Effectors 100%
  • Oligodendrocyte Precursor Cells 76%
  • Clustered Regularly Interspaced Short Palindromic Repeats 73%
  • Post Translational Protein Processing 59%
  • Transcription Factors 59%

• Row Fogo Charitable Trust Funds

  Wardlaw, J.

  UK-based charities

  10/11/14 → 9/11/17

  Project: Research

  • Stroke 100%
  • White Matter 69%
  • Lacunar Stroke 53%
  • Brain 51%
  • Blood-Brain Barrier 35%

• Mitochondria and mechanisms of axon degeneration in progressive MS

  Mahad, D.

  UK-based charities

  1/11/14 → 31/10/17

  Project: Research

• Examining the relationship between depression and cognition using multiply affected pedigrees

  McIntosh, A., Clarke, T. & Deary, I.

  24/10/14 → 24/10/17

  Project: MVM - (non-funded) undergraduate research project

  • Cognition 100%
  • Genomics 85%
  • Depression 83%
  • Scotland 48%
  • Statistical Models 47%

• Stratifying Depression using Genetic Information

  McIntosh, A. & Clarke, T.

  24/10/14 → 24/10/17

  Project: MVM - (non-funded) undergraduate research project

  • Depression 100%
  • Scotland 35%
  • Mental Disorders 24%
  • Datasets 24%

• Systematic review and meta-analysis in animal models of pain

  MacLeod, M., Currie, G. & Sena, E.

  1/10/14 → 1/10/16

  Project: MVM - (non-funded) undergraduate research project

  • Animal Models 100%
  • Meta-Analysis 68%
  • Neuralgia 47%
  • Drug Development 43%
  • Publications 38%

• Systematic reviews in animal models of psychosis

  MacLeod, M. & Sena, E.

  1/10/14 → 1/10/16

  Project: MVM - (non-funded) undergraduate research project

  • Animal Models 100%
  • Drug Development 43%
  • Psychotic Disorders 43%
  • Publications 38%
  • Schizophrenia 37%

• MICA: STRATA - Schizophrenia: Treatment Resistance And Therapeutic Advances

  Lawrie, S.

  Other

  1/10/14 → 30/09/19

  Project: Research

• Multi-modal retinal scanning for diagnostic and therapeut

  MacGillivray, T.

  MRC

  1/10/14 → 30/09/17

  Project: Research

• Understanding the Pathogenesis of Spinal Muscular Atrophy

  Murray, L.

  Non-EU-based charities

  1/10/14 → 31/10/15

  Project: Research

• Full Proposal - Ulipristal acetate versus conventional management of heavy menstrual bleeding (HMB; including uterine fibroids): a randomised controlled trial and exploration of mechanism of action (UCON trial)

  Critchley, H., Bhattacharya, S., Clark, T. J., Hapangama, D., Jane, D., Lee, M., Lumsden, M. A., Nicolls, E., Roberts, N. & Semple, S.

  UK central government bodies/local authorities, health and hospital authorities

  1/10/14 → 31/10/21

  Project: Research

  • Pregnancy Outcome 100%
  • Infertility 92%
  • Obstetrics 90%
  • Assisted Reproductive Techniques 60%
  • Placenta 46%

• www.shiftonderzhoek.com: Randomised Controlled Trial of Web Based Intervention for Functional Motor Disorders

  Stone, J.

  1/10/14 → 31/03/18

  Project: Research Collaboration with external organisation

  • Motor Disorders 100%
  • Internet-Based Intervention 26%
  • Netherlands 18%
  • Touch 14%
  • Randomized Controlled Trials 13%

• Bilingualism in Autism: Exploring parent attitudes and developing novel methods

  Rabagliati, H., Fletcher-Watson, S. & Sorace, A.

  1/10/14 → 1/07/15

  Project: University Awarded Project Funding

• Cause and Consequences of Mitochondrial Injury in Progressive Multiple Sclerosis

  Mahad, D.

  Non-EU-based charities

  1/08/14 → 31/12/15

  Project: Research

  • Farnesyltranstransferase 100%
  • Pyramidal Cells 68%
  • Synapses 60%
  • Electron Transport Complex IV 46%
  • Electron Transport 43%

• Pump Priming with the Clinician Scientist Fellowship: Implications of neuronal mitochondrial changes for axon pathology following demyelination

  Mahad, D.

  UK central government bodies/local authorities, health and hospital authorities

  1/07/14 → 30/06/15

  Project: Research

• CRG 2a SP6: Repurposing of approved drugs impacting on proteostasis for the treatment of Alzheimer's disease

  Priller, J.

  1/06/14 → 31/12/18

  Project: Project from a former institution

• Pilot testing ot a magentic resonance

  Wardlaw, J.

  UK-based charities

  1/06/14 → 31/08/14

  Project: Research

• Optimise retrieval-extinction paradigms for ameliorating stressful memories and visualise the underlying brain mechanisms by fMRI

  Wang, S.

  1/06/14 → 31/12/15

  Project: Research

  • Psychological Extinction 100%
  • Memory 63%
  • Magnetic Resonance Imaging 57%
  • Brain 42%

• SENIORS USP (Seniors - Understanding Sedentary Patterns)

  Deary, I., Fitzsimons, C., Gale, C., Mead, G. & Mutrie, N.

  Other

  1/05/14 → 31/10/17

  Project: Research

  • Sedentary Behavior 100%
  • Parturition 51%
  • Walking 40%
  • sedentary lifestyle 35%
  • physical activity 27%

• Investigating the role of the P53 signaling pathway in pa

  Murray, L.

  Non-EU-based charities

  1/05/14 → 28/02/17

  Project: Research

• Delivering personalised synthetic voices for patients with MND

  Chandran, S.

  UK-based charities

  1/05/14 → 30/04/16

  Project: Research

• MRC Dementias Platform

  Manson, J.

  Other

  1/04/14 → 31/03/20

  Project: Research

• SI.2013-0210

  Shenkin, S.

  BBSRC

  1/03/14 → 31/08/14

  Project: Research

  • Neuroimaging 100%
  • Brain 54%
  • Healthy Volunteers 29%
  • Diffusion Tensor Imaging 24%
  • Blood Pressure 14%

• Using zebrafish to study myelinated axons in vivo

  Lyons, D.

  UK-based charities

  1/02/14 → 28/02/19

  Project: Research

  • Myelin Sheath 100%
  • Oligodendroglia 79%
  • myelination 62%
  • Axons 48%
  • Zebrafish 42%