Centre for Clinical Brain Sciences

2025

The medicalisation of menstruation: a double-edged sword

Marwick, K., Ford, A. & Campbell , J., 23 Apr 2025, Wellcome Open Research, (Wellcome Open Research ).

Research output: Working paper › Preprint

Direct Retinal Imaging for Shock Resuscitation in Critical Ill Adults II (D-RISC II)

Cooper, G., Burke, J., Hamid, C., Godden, E., Dhaun, N., King, S., MacGillivray, T. J., Baillie, J. K., Griffith, D. M. & MacCormick, I. J. C., 31 Jan 2025, medRxiv.

Research output: Working paper › Preprint

Direct Retinal Imagng for Shock Resuscitation in Critically Ill Adults (D-RISC II)

Cooper, G., Burke, J., Godden, E., Hamid, C., Dhaun, N., King, S., MacGillivray, T. J., Baillie, J. K., Griffith, D. M. & Maccormick, I. J. C., 31 Jan 2025, medRxiv, (medrXiv).

Research output: Working paper › Preprint

Systematic Identification of Context-Dependent Gene Essentiality in Glioblastoma: The GBM-CoDE Platform

Foster, M. T., Ewing, A., Frame, M., Brennan, P. M., Khamseh, A., Beentjes, S. V., Carragher, N. O. & Semple, C. A., 29 Jan 2025, bioRxiv.

Research output: Working paper › Preprint

2024

Therapeutic window for treatment of prion disease defined by timed depletion of Prion protein

Bradford, B., Marshall, A., Tuzi, N., Brown, D., Kisielewski, D., Summers, K., Perry, H., Piccardo, P., Clarke, A. & Manson, J. C., 18 Nov 2024, (E-pub ahead of print) bioRxiv.

Research output: Working paper › Preprint

Open Access

File

Fine-mapping genomic loci refines bipolar disorder risk genes

Koromina, M., Ravi, A., Panagiotaropoulou, G., Schilder, B. M., Humphrey, J., Braun, A., Bidgeli, T., Chatzinakos, C., Coombes, B., Kim, J., Liu, X., Terao, C., O 'Connell, K. S., Adams, M., Adolfsson, R., Alda, M., Alfredsson, L., Andlauer, T. F. M., Andreassen, O. A. & Antoniou, A. & 110 others, Baune, B. T., Bengesser, S., Biernacka, J., Boehnke, M., Bosch, R., Cairns, M., Carr, V. J., Casas, M., Catts, S., Cichon, S., Corvin, A., Craddock, N., Dafnas, K., Dalkner, N., Dannlowski, U., Degenhardt, F., Di Florio, A., Dikeos, D., Fellendorf, F. T., Ferentinos, P., Forstner, A. J., Forty, L., Frye, M., Fullerton, J. M., Gawlik, M., Gizer, I. R., Gordon-Smith, K., Green, M. J., Grigoroiu-Serbanescu, M., Guzman-Parra, J., Hahn, T., Henskens, F., Hillert, J., Jablensky, A. V., Jones, L., Jones, I., Jonsson, L., Kelsoe, J. R., Kircher, T., Kirov, G., Kittel-Schneider, S., Kogevinas, M., Landén, M., Leboyer, M., Lenger, M., Lissowska, J., Lochner, C., Loughland, C., MacIntyre, D., Martin, N. G., Maratou, E., Mathews, C. A., Mayoral, F., McElroy, S. L., McGregor, N. W., McIntosh, A., McQuillin, A., Michie, P., Milanova, V., Mitchell, P. B., Moutsatsou, P., Mowry, B., Müller-Myhsok, B., Myers, R., Nenadić, I., Nöthen, M. M., O'Donovan, C., O'Donovan, M., Ophoff, R. A., Owen, M. J., Pantelis, C., Pato, C., Pato, M. T., Patrinos, G. P., Pawlak, J. M., Perlis, R. H., Porichi, E., Posthuma, D., Ramos-Quiroga, J. A., Reif, A., Reininghaus, E. Z., Ribasés, M., Rietschel, M., Schall, U., Schulze, T. G., Scott, L., Scott, R. J., Serretti, A., Weickert, C. S., Smoller, J. W., Artigas, M. S., Stein, D. J., Streit, F., Toma, C., Tooney, P., Vieta, E., Vincent, J. B., Waldman, I. D., Weickert, T., Witt, S. H., Świątkowska, B., Hong, K. S. S., Ikeda, M., Iwata, N., Ripke, S., Won, H.-H., Edenberg, H. J., Raj, T., Coleman, J. R. I. & Mullins, N., 17 Sept 2024, medRxiv.

Research output: Working paper › Preprint

The Fragile X Messenger Ribonucleoprotein 1 regulates the morphology and maturation of human and rat oligodendrocytes

Ramesh, V., Kougianou, I., Tsoukala, E., Kozic, Z., Burr, K., Viswanath, B., Hampton, D., Story, D., Reddy, B. K., Pal, R., Dando, O., Kind, P. C., Chattarji, S., Selvaraj, B. T., Chandran, S. & Zoupi, L., 19 Aug 2024, bioRxiv.

Research output: Working paper › Preprint

Human induced pluripotent stem cell-derived microglia contribute to the pathophysiology of Fragile X syndrome via increased RAC1 signaling

Banerjee, P., Das Sharma, S., Burr, K., Morris, K., Ritakari, T., Baxter, P., Cooper, J., Cardinalli, A., Subash, S., Paza, E., Story, D., Chattarji, S., Kind, P. C., Carragher, N. O., Thangaraj Selvaraj, B., Priller, J. & Chandran, S., 28 Jun 2024, University of Edinburgh.

Research output: Working paper › Preprint

Antidepressant Exposure and DNA Methylation: Insights from a Methylome-Wide Association Study

Davyson, E., Shen, X., Huider, F., Adams, M., Borges, K., McCartney, D., Barker, L., Van Dongen, J., Boomsma, D., Weihs, A., Grabe, H., Kühn, L., Teumer, A., Völzke, H., Zhu, T., Kaprio, J., Ollikainen, M., David, F. S., Meinert, S. & Stein, F. & 22 others, Forstner, A. J., Dannlowski, U., Kircher, T., Tapuc, A., Czamara, D., Binder, E. B., Brückl, T., Kwong, A., Yousefi, P., Wong, C. C. Y., Arseneault, L., Fisher, H. L., Mill, J., Cox, S., Redmond, P., Russ, T. C., van den Oord, E., Aberg, K. A., Penninx, B., Marioni, R. E., Wray, N. R. & McIntosh, A. M., 3 May 2024, medRxiv.

Research output: Working paper › Preprint

Genome-wide study of half a million individuals with major depression identifies 697 independent associations, infers causal neuronal subtypes and biological targets for novel pharmacotherapies

McIntosh, A. M., Lewis, C. M., Adams, M. J. & Psychiatric Genomics Consortium Major Depressive Disorder Working Group, 1 May 2024, medRxiv.

Research output: Working paper › Preprint

Implementation of a shared decision making process for severe stroke-a mixed methods study

Visvanathan, A., Morton, S., Macraild, A., Black, P., Barber, M., Dennis, M., O'Brien, R. & Mead, G., 23 Feb 2024, medRxiv.

Research output: Working paper › Preprint

2023

Inclusive Strategies for Children with Developmental Disabilities in Sub-Saharan African Mainstream Classrooms: a Systematic Review of Stakeholder Experiences, Attitudes and Perspectives

Genovesi, E., Gaches, A., McKenzie, J., Hanlon, C. & Hoekstra, R., 1 Oct 2023, (Review of Educational Research).

Research output: Working paper › Preprint

Feasibility Study of the CT Clock Tool for Estimating Onset Time of Ischaemic Stroke: Study Protocol

Mair, G., Whiteley, W., Chappell, F., MacRaild, A. & Wardlaw, J., 8 Sept 2023, medRxiv.

Research output: Working paper › Preprint

Reducing stigma and improving access to care for people with mental health conditions in the community: protocol for a multi-site feasibility intervention study (Indigo-Local)

Semrau, M., Gronholm, P. C., Eaton, J., Maulik, P. K., Ayele, B., Bakolis, I., Mendon, G. B., Bhattarai, K., Brohan, E., Cherian, A. V., Daniel, M., Girma, E., Gurung, D., Hailemariam, A., Hanlon, C., Healey, A., Kallakuri, S., Li, J., Loganathan, S. & Ma, N. & 9 others, Ma, Y., Metsahel, A., Ouali, U., Yaziji, N., Zgueb, Y., Zhang, W., Zhang, X., Thornicroft, G. & Votruba, N., 18 Aug 2023, (Research square).

Research output: Working paper › Preprint

General and specific patterns of cortical gene expression as substrates of complex cognitive functioning

Moodie, J. E., Harris, S., Harris, M., Buchanan, C., Taylor, A., Redmond, P., Liewald, D. C., Shenkin, S. D., Russ, T. C., Muñoz Maniega, S., Luciano, M., Corley, J., Stolicyn, A., Shen, X., Bastin, M., Wardlaw, J. M., McIntosh, A. M., Whalley, H., Tucker-Drob, E. M. & Deary, I. J. & 1 others, Cox, S. R., 20 Jul 2023, bioRxiv.

Research output: Working paper › Preprint

Understanding the genetic complexity of puberty timing across the allele frequency spectrum

ABCTB Investigators, 20 Jun 2023, medRxiv.

Research output: Working paper › Preprint

Understanding quantity and intensity of hospital rehabilitation using electronic health record data

Georgiev, K., Doudesis, D., McPeake, J., Mills, N. L., Fleuriot, J., Shenkin, S. D. & Anand, A., 30 May 2023, medRxiv.

Research output: Working paper › Preprint

Cardiovascular events and venous thromboembolism after primary malignant and non-malignant brain tumour diagnosis: A population matched cohort study in Wales (United Kingdom)

Poon, M. T., Brennan, P. M., Jin, K., Sudlow, C. L. & Figueroa, J. D., 22 Mar 2023, medRxiv.

Research output: Working paper › Preprint

Childhood cognitive ability and self-harm and suicide in later life

Iveson, M. H., Ball, E. L., Whalley, H. C., Deary, I. J., Cox, S. R., Batty, G. D., John, A. & McIntosh, A. M., 11 Feb 2023, medRxiv, 30 p.

Research output: Working paper › Preprint

Phenome-wide analysis identifies parent-of-origin effects on the human methylome associated with changes in the rate of aging

Gao, C., Amador, C., Walker, R. M., Campbell, A., Madden, R. A., Adams, M. J., Bai, X., Liu, Y., Li, M., Hayward, C., Porteous, D. J., Shen, X., Evans, K. L., Haley, C. S., McIntosh, A. M., Navarro, P. & Zeng, Y., 20 Jan 2023, bioRxiv.

Research output: Working paper › Preprint

2022

Brain connectivity changes underlying depression and fatigue in relapsing-remitting multiple sclerosis: a systematic review

Kampaite, A., Gustafsson, R., York, E. N., Foley, P., MacDougall, N., Bastin, M. E., Chandran, S., Waldman, A. & Meijboom, R., 7 Dec 2022, (Submitted).

Research output: Working paper › Preprint

Dementia diagnosis and prevalence in the Lothian Birth Cohort 1936 using medical data linkage

Mullin, D., Stirland, L., Buchanan, E., Lothian, N., Cox, S. R., Deary, I. J., Centre, A., Centre, A., Page, D., Centre, A., Shenkin, S. D., Szalek, A., Taylor, A., Weatherdon, G., Wilkinson, T. & Russ, T., 18 Nov 2022, medRxiv.

Research output: Working paper › Preprint

Bilingualism in autism: Evidence and recommendations for education practice

Digard, B. & Davis, R., 2 Aug 2022, OSF Preprints, 2 p.

Research output: Working paper › Preprint

File

Early-life inflammatory markers and subsequent episodes of depression and psychotic experiences in the ALSPAC birth cohort

Edmondson-Stait, A. J., Shen, X., Adams, M. J., Barbu, M. C., Jones, H. J., Miron, V. E., Allardyce, J., Boardman, J. P., Lawrie, S. M., McIntosh, A. M., Khandaker, G. M., Kwong, A. S. F. & Whalley, H. C., 12 Jul 2022, medRxiv.

Research output: Working paper › Preprint

Computer-assisted analysis of routine EEG to identify hidden biomarkers of epilepsy: Protocol for a systematic review

Lemoine, É., Briard, J. N., Rioux, B., Podbielski, R., Nauche, B., Toffa, D., Keezer, M., Lesage, F., Nguyen, D. K. & Assi, E. B., 6 Jun 2022, medRxiv.

Research output: Working paper › Preprint

Mental health outcomes following COVID-19 infection: Evidence from 11 UK longitudinal population studies

Thompson, E. J., Stafford, J., Moltrecht, B., Huggins, C. F., Kwong, A. S. F., Shaw, R. J., Zaninotto, P., Patel, K., Silverwood, R. J., McElroy, E., Pierce, M., Green, M. J., Bowyer, R. C. E., Maddock, J., Tilling, K., Katikireddi, S. V., Ploubidis, G. B., Porteous, D. J., Timpson, N. & Chaturvedi, N. & 2 others, Steves, C. J. & Patalay, P., 16 May 2022, medRxiv.

Research output: Working paper › Preprint

Ontology-based and weakly supervised rare disease phenotyping from clinical notes

Dong, H., Suárez-Paniagua, V., Zhang, H., Wang, M., Casey, A., Davidson, E., Chen, J., Alex, B., Whiteley, W. & Wu, H., 1 May 2022, ArXiv.

Research output: Working paper › Preprint

Community views on medication use in fragile X syndrome

Eley, S., McKechanie, A. G. & Stanfield, A. C., 25 Mar 2022, Research Square , 10 p.

Research output: Working paper › Preprint

Automated Clinical Coding: What, Why, and Where We Are?

Dong, H., Falis, M., Whiteley, W., Alex, B., Ji, S., Chen, J. & Wu, H., 21 Mar 2022, ArXiv, 8 p.

Research output: Working paper › Preprint

File

Detection of multiple retinal diseases in ultra-widefield fundus images using deep learning: data-driven identification of relevant regions

Engelmann, J., McTrusty, A. D., MacCormick, I. J. C., Pead, E., Storkey, A. & Bernabeu, M. O., 11 Mar 2022, ArXiv.

Research output: Working paper › Preprint

Motor Neuron Disease is not clustered or associated with socioeconomic deprivation in Scotland

Chang, Y.-T., Kearns, P. K. A., Newton, J., Larraz, J., Forbes, D., Beswick, E., Leighton, D., Langlands, G., Swingler, R. J., Chandran, S. & Pal, S., 28 Feb 2022, medRxiv.

Research output: Working paper › Preprint

Oligodendrocytes form paranodal bridges that generate chains of myelin sheaths that are vulnerable to degeneration with age

Call, C. L., Neely, S. A., Early, J. J., James, O. G., Zoupi, L., Williams, A. C., Chandran, S., Lyons, D. A. & Bergles, D. E., 17 Feb 2022, bioRxiv.

Research output: Working paper › Preprint

Electronic Informed Consent: effects on enrolment, practical and economic benets, challenges, and drawbacks. Studies within Randomised Controlled Trials. Systematic Review.

Mazzochi, A. T., Dennis, M. & Chun, H.-Y. Y., 10 Feb 2022, Research Square .

Research output: Working paper › Preprint

File

Data-driven analysis shows robust links between fatigue and depression in early multiple sclerosis

Chang, Y.-T., Kearns, P. K. A., Carson, A., Gillespie, D. C., Meijboom, R., Kampaite, A., Hernández, M. D. C. V., Weaver, C., Stenson, A., MacDougall, N., O’Riordan, J., Macleod, M. A., Carod-Artal, F. J., Connick, P., Waldman, A. D., Chandran, S. & Foley, P., 13 Jan 2022, medRxiv.

Research output: Working paper › Preprint

2021

Bilingualism in autism: Evidence and recommendations for clinical practice

Digard, B. & Davis, R., 12 Oct 2021, OSF Preprints, 2 p.

Research output: Working paper › Preprint

File

FutureMS Cohort Profile: A Scottish Multi-Centre Inception Cohort Study of Relapsing-Remitting Multiple Sclerosis

Kearns, P. K. A., Martin, S. J., Chang, J., Meijboom, R., York, E. N., Chen, Y., Weaver, C., Stenson, A., Hafezi, K., Thomson, S., Freyer, E., Murphy, L., Harroud, A., Foley, P., Hunt, D., McLeod, M., O’Riordan, J., Carod-Artal, F. J., MacDougall, N. J. J. & Baranzini, S. E. & 3 others, Waldman, A. D., Connick, P. & Chandran, S., 8 Sept 2021, medRxiv.

Research output: Working paper › Preprint

A systematic review and meta-analysis of non-workplace interventions to reduce time spend in sedentary in adults

Hall, J. F., Corepal, R., Crocker, T. F., Lam, N., Burton, L.-J., Birch, K., Carter, G., Clarke, D. J., English, C., Farrin, A. J., Fitzsimons, C., Hall, J., Holloway, I., Ozer, S., Lawton, R., Mead, G., Morton, S., Patel, A. & Forster, A., 29 May 2021, medRxiv.

Research output: Working paper › Preprint

File

The Automated Systematic Search Deduplicator (ASySD): a rapid, open-source, interoperable tool to remove duplicate citations in biomedical systematic reviews

Hair, K., Bahor, Z., Macleod, M., Liao, J. & Sena, E. S., 4 May 2021, bioRxiv, 16 p.

Research output: Working paper › Preprint

DNA methylation and brain dysmaturation in preterm infants

Wheater, E. N. W., Galdi, P., McCartney, D. L., Blesa, M., Sullivan, G., Stoye, D. Q., Lamb, G., Sparrow, S., Murphy, L., Wrobel, N., Quigley, A. J., Semple, S., Thrippleton, M. J., Wardlaw, J. M., Bastin, M. E., Marioni, R. E., Cox, S. R. & Boardman, J. P., 10 Apr 2021, medRxiv.

Research output: Working paper › Preprint

Results of a randomised controlled trial comparing two different incentives to improve survey response rates

Macleod, M. R., Hair, K., Ezgi, T. A., Craske, D., Shinton, S., Campbell, A., Mellifont, B. & Thomson, L., 10 Feb 2021, SocArXiv.

Research output: Working paper › Preprint

2020

The hepatic compensatory response to elevated systemic sulfide promotes diabetes

Carter, R. N., Gibbins, M. T. G., Barrios-Llerena, M. E., Wilkie, S. E., Freddolino, P. L., Libiad, M., Vitvitsky, V., Emerson, B., Le Bihan, T., Brice, M., Su, H., Denham, S. G., Homer, N. Z. M., Mc Fadden, C., Tailleux, A., Faresse, N., Sulpice, T., Briand, F., Gillingwater, T. & Ahn, K. H. & 9 others, Singha, S., McMaster, C., Hartley, R. C., Staels, B., Gray, G. A., Finch, A. J., Selman, C., Banerjee, R. & Morton, N. M., 1 Oct 2020, bioRxiv.

Research output: Working paper › Preprint

Supporting the resilience and retention of frontline care workers in care homes for older people: A scoping review and thematic synthesis

Johnston, L., Malcolm, C., Rambabu, L., Hockley, J. & Shenkin, S. D., 8 Sept 2020, medRxiv.

Research output: Working paper › Preprint

Centre for Clinical Brain Sciences

Research output

Search results