Centre for Genomic and Experimental Medicine

Projects

Projects per year 1994 2000 2001 2002 2004 2005 2006 2007 2008 2009 2010 2011 2012 2024

• 5 Active
• 187 Finished

Projects per year

Search results

• Finished

  Depression Detectives

  Beange, I., McIntosh, A., Iveson, M., Kwong, A., Adams, M., Whalley, H., Kirkham, E., Smith, D., MacSweeney, N., Barbu, M. C. & Huggins, C.

  20/02/21 → 8/09/21

  Project: Other (Non-Funded/Miscellaneous)

  • Research Worker 100%
  • Depression 100%
  • Lived Experience 55%
  • Research 55%
  • Facebook 33%

• Targeting the Hippo Pathway for Osteosarcoma Therapy

  Hansen, C., Bagnaninchi, P. & Salter, D.

  UK-based charities

  1/11/17 → 31/10/18

  Project: Research

• PREdiCCT - The Prognostic Effect of Environmental Factors in Crohn's and Colitis

  Lees, C. & Ennis, H.

  UK central government bodies/local authorities, health and hospital authorities

  1/11/16 → 31/12/22

  Project: Research

• The Scottish Genomes Partnership (SGP)

  Aitman, T.

  MRC

  1/02/16 → 29/02/20

  Project: Research

  • Haplotype 100%
  • Mutation 96%
  • Phenotype 92%
  • Glycosylation 80%
  • Protein Sequencing 80%

• The Scottish Genomes Partnership

  Aitman, T.

  UK central government bodies/local authorities, health and hospital authorities

  1/02/16 → 29/02/20

  Project: Research

  • Haplotype 100%
  • Mutation 96%
  • Phenotype 92%
  • Glycosylation 80%
  • Protein Sequencing 80%

• Characterisation of autophagic clearance of mitochondrial damage associated molecular patterns in inflammatory bowel disease

  Ho, G.

  4/01/16 → 31/07/16

  Project: MVM - (non-funded) undergraduate research project

  • Clearance 100%
  • Inflammatory Bowel Disease 100%
  • Mitochondrion 100%
  • Crohn's Disease 66%
  • Autophagy 66%

• A pilot study on the genetic epidemiology of oral health disorders with in the Generation Scotland cohort

  Bermingham, M., Walls, A., Porteous, D. & Campbell, A.

  1/10/15 → 30/04/16

  Project: University Awarded Project Funding

  • Major Depressive Episode 100%
  • DNA Methylation 100%
  • Chronic Obstructive Pulmonary Disease 100%
  • Respiratory Physiology 100%
  • Respiratory Function 100%

• Development of Magnetic Nanoparticle Bearing Mesenchymal Stem Cells for Magnetic Hypertermia treatment of Sarcomas

  Salter, D.

  UK-based charities

  1/09/15 → 28/02/17

  Project: Research

• PREdiCCT - The Prognostic Effect of Environmental Factors in Crohn's and Colitis

  Lees, C.

  UK-based charities

  1/06/15 → 31/03/21

  Project: Research

• PREdiCCT - The Prognostic Effect of Environmental Factors in Crohn's and Colitis

  Lees, C.

  UK-based charities

  1/06/15 → 31/05/19

  Project: Research

• PREdiCCT - The Prognostic Effect of Environmental Factors in Crohn's and Colitis

  Lees, C.

  UK-based charities

  1/06/15 → 31/05/19

  Project: Research

• An application to fund the UK CF Gene Therapy Consortium core costs

  Boyd, C.

  UK-based charities

  1/04/15 → 31/03/17

  Project: Research

• PreMDD: Predicting major depressive disorder

  Porteous, D., Nicodemus, K., Agakov, F., McKeigue, P., Campbell, A., Bermingham, M., Munoz, D. U., McIntosh, A. & Marriage, H. M.

  1/04/15 → 30/09/15

  Project: University Awarded Project Funding

  • Learning 100%
  • Major Depressive Episode 90%
  • Prediction 90%
  • Lifespan 54%
  • Family Health 45%

• Role of UBR5 in Skeletal Homeostasis: Osteoarthritis, Heterotopic Ossification and Chondrocyte Hypertrophy

  Ditzel, M., Salter, D., Ralston, S. & Hill, B.

  1/01/15 → 1/01/18

  Project: MVM - (non-funded) undergraduate research project

  • Skeletal Homeostasis 100%
  • Chondrocyte 100%
  • Osteoarthritis 100%
  • Heterotopic Ossification 100%
  • Tissues 100%

• Mitochondria damage associated molecular patterns in IBD

  Ho, G.

  1/12/14 → 1/06/16

  Project: University Awarded Project Funding

  • Inflammatory Bowel Disease 100%
  • Gut 100%
  • Inflammatory Disorder 50%
  • Pathogenesis 25%
  • Etiology 25%

• NG2/CSPG4 in Osteosarcoma : functional roles and novel therapeutic target

  Salter, D.

  UK-based charities

  1/10/14 → 30/09/17

  Project: Research

  • Electric Potential 100%
  • Aggrecanase 50%
  • ADAMTS 50%
  • Transmembrane Protein 50%
  • Molecule 50%

• Transfer from Imperial - ELABORATE

  Aitman, T.

  EU government bodies

  1/10/14 → 31/05/17

  Project: Research

  • Rat 100%
  • Blood Vessel Reactivity 86%
  • Complement Factor 86%
  • Metabolic Syndrome 86%
  • Hypoxia 86%

• Venture and Innovation Award

  Boyd, C.

  UK-based charities

  1/07/14 → 31/03/15

  Project: Research

• Pump Priming

  Lees, C.

  UK industry, commerce and public corporations

  1/06/14 → 31/12/17

  Project: Research

• UK Cystic Fibrosis Gene Therapy Consortium: Virus Production and Testing - Bridging Salary Costs

  Boyd, C.

  UK central government bodies/local authorities, health and hospital authorities

  1/11/13 → 28/02/14

  Project: Research

• Investigating the role of DNA supercoiling in Rheumatoid Arthritis

  Hauser, B.

  UK-based charities

  1/10/13 → 30/06/15

  Project: Research

• An interim application to fund the UK CF Gene Therapy Consortium core costs

  Boyd, C.

  UK-based charities

  1/01/13 → 28/02/14

  Project: Research

• Psteoprotegerin Antibodies

  Riches, P. & Ralston, S.

  UK-based charities

  1/01/13 → 31/01/16

  Project: Research

• Investigating the molecular and cellularconsequences of disrupted in Schizophrenia 1 in patient derived nueral stem cells

  Porteous, D. & McIntosh, A.

  UK-based charities

  1/10/12 → 30/09/16

  Project: Research

• Cognitive change in older persons: the assessment of cognitive decline, its relation to neural pathologies, and determining the potential for intervention to delay or prevent the onset of dementia

  Marioni, R.

  UK-based charities

  1/10/12 → 31/08/14

  Project: Research

  • Molecular Genetics 100%
  • Intelligence 100%
  • Socioeconomic Status 100%
  • Genetics 71%
  • Genetic Correlation 57%

• HIGH ACCURACY, LOW VOLUME HOST DIRECTED DETECTION OF NEONATAL SEPSIS

  Ghazal, P. & Dickinson, P.

  UK central government bodies/local authorities, health and hospital authorities

  1/07/12 → 31/12/13

  Project: Research

  • Immunity 100%
  • Comprehension 87%
  • Host 70%
  • Microbiome 50%
  • Gene Expression 50%

• Investigating the importance of NOD2 and TIP60 in the pathogenesis of lleal Chrohns disease

  Nimmo, E., Satsangi, J. & Stevens, C.

  UK-based charities

  1/07/12 → 31/12/13

  Project: Research

• An iPS model of Bipolar Disorder based on a Large Family with a Highly Penetrant Mutation

  McIntosh, A., Chandran, S. & Evans, K.

  UK central government bodies/local authorities, health and hospital authorities

  1/07/12 → 31/12/16

  Project: Research

  • Glycine Receptor 100%
  • Receptor Subunit 100%
  • 4 Aminobutyric Acid Receptor 100%
  • RNA 100%
  • 4 Aminobutyric Acid 62%

• ANTI INFLAMMATORY CELL CONTACT

  Gray, M. & Gray, D.

  MRC

  1/05/12 → 30/09/15

  Project: Research

  • Cells 100%
  • Inflammation 81%
  • Self Concept 53%
  • Plasmacytoid Dendritic Cell 44%
  • Immunity 44%

• An investigation into the epigenetic alterations in the T Helper 14 pathway in the pathogenensis of Crohns disease

  Kennedy, N.

  UK-based charities

  1/05/12 → 30/09/15

  Project: Research

  • Inflammatory Bowel Disease 100%
  • Faecal Calprotectin 58%
  • Crohn's Disease 54%
  • Sample 54%
  • Patient 39%

• IGMM STUDENTS

  Porteous, D.

  MRC

  1/04/12 → 31/07/13

  Project: Research

• INVESTIGATION OF MICRO RNAS AS BIOMARKERS AND DRUG TARGETS FOR BIPOLAR DISORDER

  Evans, K., McIntosh, A. & Porteous, D.

  UK central government bodies/local authorities, health and hospital authorities

  1/04/12 → 30/09/14

  Project: Research

• Full Appl: Oxford Led DPFS Application

  Boyd, C.

  MRC

  1/03/12 → 31/10/13

  Project: Research

• Do age related changes in RAMKL-induced signalling pathways explain the late onset of SQSTM 1-linked Pagets

  Daroszewska, A., Ralston, S. & van 't Hof, R.

  UK-based charities

  28/11/11 → 27/11/12

  Project: Research

• CONTROL OF TRANSLATION ELONGATION FACTO eEF1A ISOFORM SWITCHING

  Abbott, C.

  UK-based charities

  1/06/11 → 31/07/14

  Project: Research

  • Translation Elongation 100%
  • Elongation Factor 100%
  • Isoform 100%
  • Diptera 66%
  • Nematode 66%

• GRANT GT011- Phase 2 Clinical Study for Wave Gene Therapy Product

  Boyd, C.

  UK-based charities

  1/04/11 → 31/12/11

  Project: Research

• Establishing a national biobank to integrate genomic, metabolomic and microbial studies in inflammatory bowel disease in Scotland

  Satsangi, J.

  UK central government bodies/local authorities, health and hospital authorities

  1/04/11 → 1/12/12

  Project: Research

• Understanding Current and Novel Modes of Action in Treatment of Schizophrenia Through the DISC 1 Pathway

  Porteous, D. & Millar, K.

  UK industry, commerce and public corporations

  1/04/11 → 31/08/13

  Project: Research

• Generation Scotland

  Porteous, D.

  UK central government bodies/local authorities, health and hospital authorities

  1/04/11 → 31/03/14

  Project: Research

  • Association 100%
  • Genetics 78%
  • Nested Gene 67%
  • Genome-Wide Association Study 49%
  • Major Depressive Disorder 40%

• BUSINESS OPPORTUNITIES FOR GENERATION SCOTLAND

  Porteous, D.

  Other

  14/02/11 → 30/09/13

  Project: Research

• Genetic Variation in HCN1-4 and it's relationship to cognition and depression in individuals from the Generation Scotland: Scotrish Family Health Study

  McIntosh, A., Deary, I., Evans, K., Hall, J. & Thomson, P.

  UK central government bodies/local authorities, health and hospital authorities

  1/01/11 → 31/03/12

  Project: Research

  • Cognition 100%
  • Depression 100%
  • Genetic Variation 100%
  • Neuroticism 100%
  • HCN Channel 100%

• Functional Charicterisations of EphA2 mediated signalling in the context of the pancreatic cancer tumour stelliate cell interaction

  Duxbury, M. & Frame, M.

  UK-based charities

  1/01/11 → 31/12/12

  Project: Research

• Clinical PHD Studentship Dr Barbara Hauser-Role of Osteoprotegerin Autoantiebodies in the Pathgenesis of Osteopororsis in Rheumatic Diseases

  Ralston, S.

  UK-based charities

  1/12/10 → 30/11/14

  Project: Research

• IBD-BIOM

  Ventham, N.

  1/10/10 → 1/10/16

  Project: University Awarded Project Funding

• Grand Challenge: Understanding current and novel modes of action in treatment of schizophrenia through the DISC 1 Path.

  Porteous, D.

  UK industry, commerce and public corporations

  1/10/10 → 31/08/13

  Project: Research

• MCM Lead application

  Riches, P., Ralston, S. & Wilson, J.

  UK central government bodies/local authorities, health and hospital authorities

  1/10/10 → 30/09/13

  Project: Research

• Molecular evolution and variation in genomic regions with low recombination

  Charlesworth, B. & Campos Parada, J.

  BBSRC

  1/07/10 → 30/09/13

  Project: Research

  • Nested Gene 100%
  • Drosophila Melanogaster 93%
  • Molecular Evolution 86%
  • Mutation 73%
  • Crossing over 70%

• UK CF Gene Therapy Consortium Grant Funding

  McLachlan, G., Boyd, C., Collie, D., Cunningham, S., Greening, A., Innes, A., Ogilvie, V. & Porteous, D.

  UK-based charities

  1/04/10 → 30/07/12

  Project: Research

  • Sheep 100%
  • Dose 72%
  • Cationic Lipid 63%
  • Gene Transfer Agent 63%
  • Cystic Fibrosis 63%

• EURATRANS

  Burdon, T., Aitman, T. & Mullins, J.

  EU government bodies

  1/04/10 → 31/03/15

  Project: Research

  • Embryonic Stem Cell 100%
  • Rat 99%
  • Phosphoribosyltransferase 46%
  • Self Concept 34%
  • Rodent 34%

• Amgen Bone Biology Research Fellowship.

  Ralston, S.

  UK-based charities

  1/04/10 → 31/01/14

  Project: Research