Centre for Inflammation Research

Projects

Projects per year 1994 2000 2002 2004 2006 2007 2008 2009 2010 2011 2012 2013 2014 2026

• 1 Not started
• 11 Active
• 280 Finished

Projects per year

Search results

• Active

  Perceptive soft surgical robots

  Yang, Y., Giorgio-Serchi, F., Mole, D. & Bagnaninchi, P.

  1/02/23 → 31/01/24

  Project: Research

  • Robotic surgery 100%
  • Capacitive sensors 92%
  • robots 90%
  • Robots 46%
  • sensors 44%

• Sir Henry Dale Fellowship: Does stroke impair immunological memory and increase infectious disease risk during the chronic phase of recovery

  McCulloch, L.

  1/04/21 → 31/03/26

  Project: Research

  • Stroke 100%
  • Endemic Diseases 38%
  • Biological Factors 31%
  • Pandemics 31%
  • Immune System 23%

• Exploring physiological impacts for bioactive lipids on mucosal immune functions during ageing

  Yao, C., Zhou, Y. & Rossi, A.

  1/10/20 → 30/09/24

  Project: Research

• Respiratory pathogen-specific airway immunity assessment using innovative in situ sampling and imaging techniques

  Humphries, D.

  1/02/20 → …

  Project: Research Collaboration with external organisation

• Edinburgh Orthopaedic Relational Database

  MacDonald, D., Simpson, H., Yapp, L. & Clement, N.

  1/01/20 → 31/12/25

  Project: Research

  • Orthopedics 100%

• IRC Next Steps Plus: Photonic Pathogen Theranostics - Point-of-care image guided photonic therapy of bacterial and fungal infection?

  Dhaliwal, K., Bradley, M., Harrison, E., Megia Fernandez, A., Mills, B., Walsh, T. & Williams, G.

  EPSRC

  1/07/19 → 30/06/23

  Project: Research

  • Photosensitizing Agent 100%
  • starters 99%
  • Dye 90%
  • bacteria 82%
  • activity (biology) 79%

• Watching macrophages: new tools for imaging acute inflammation

  Vendrell Escobar, M.

  1/09/15 → …

  Project: MVM - (non-funded) undergraduate research project

  • Macrophages 100%
  • Thioglycolates 20%
  • Cell Physiological Phenomena 18%
  • Esterases 17%
  • Acute Lung Injury 16%

• Live imaging of signalling events during wound repair and tumour induced inflammation in a zebrafish model

  Feng, Y.

  1/01/15 → …

  Project: MVM - (non-funded) undergraduate research project

  • Zebrafish 100%
  • Neoplasms 58%
  • Wound Healing 43%
  • Wounds and Injuries 39%
  • Embryonic Structures 26%

• Live imaging study of metabolic change in pre-neoplastic cells and the host inflammation response in a zebrafish tumour model

  Feng, Y.

  1/01/15 → …

  Project: MVM - (non-funded) undergraduate research project

  • Zebrafish 100%
  • Neoplasms 47%
  • Glucose 46%
  • Citric Acid Cycle 30%
  • Inflammation 28%

• Establishment and live imaging studies of a B cell lymphoma model in zebrafish

  Feng, Y.

  1/05/14 → …

  Project: University Awarded Project Funding

• In vivo live imaging and genetic analysis of oncogene induced senescence, and the host response during the initiation of tumourigenesis

  Feng, Y. & Costa, J.

  1/05/14 → …

  Project: University Awarded Project Funding

• Not started

  Extracellular vesicles in urological malignancies

  Rimmer, M., Gregory, C. & Mitchell, R.

  Project: Research

• Finished

  Enabling soft surgical robots with precision proprioception

  Yang, Y., Giorgio-Serchi, F. & Mole, D.

  1/12/21 → 31/08/22

  Project: Research

  • Institutional Trust 100%
  • Robot 80%

• Use of CRISPR-based genome-wide approach for identification of vulnerabilities in canine oral melanoma

  Parkinson, N., Parys, M., Argyle, D., Baillie, K., Hupp, T. & Schoenebeck, J.

  Non-EU-based charities

  1/03/21 → 28/02/23

  Project: Research

• Use of CRISPR-based genome-wide approach for identification of vulnerabilities in canine oral melanoma

  Parkinson, N., Parys, M., Argyle, D., Baillie, K., Hupp, T. & Schoenebeck, J.

  Non-EU-based charities

  1/03/21 → 28/02/23

  Project: Research

• Pathology PhD

  Dorward, D.

  UK-based charities

  1/10/19 → 31/12/22

  Project: Research

• Investigating the Molecular Heterogeniety of Intestinal Macrophages in Drug Naive, Newly Diagnosed Crohn's Disease Patients

  Ho, G., Bain, C. & Jones, G.

  UK-based charities

  1/01/19 → 31/12/19

  Project: Research

• Investigation of the role of glucose availability and metabolism on short and long-term neutrophil behaviour

  Forbes, S., Walmsley, S. & Whyte, M.

  3/09/18 → 1/09/22

  Project: University Awarded Project Funding

  • supervisors 100%
  • neutrophils 66%
  • glucose 42%
  • metabolism 41%

• Innovation Initiative Grant 2018

  Davidson, D.

  1/07/18 → 30/06/19

  Project: University Awarded Project Funding

• ISSF3 funding: Generation of a constitutive Cas9 pig for gene-level pharmaceutical target validation.

  Baillie, K., Clohisey Hendry, S. & Lillico, S.

  1/07/18 → 30/06/20

  Project: University Awarded Project Funding

  • swine 100%
  • gene editing 96%
  • funding 86%
  • drugs 51%
  • tissues 34%

• Investigation of Disease Associations of Site¿¿¿specific Degrees of Methylation Using Genome¿¿¿Wide Association Studies

  Knott, S., Cunningham, S. & Ly, T.

  UK-based charities

  18/06/18 → 26/07/18

  Project: Research

• Scientific Conference

  Cunningham, S.

  UK-based charities

  1/03/18 → 31/12/19

  Project: Research

• Institute for Academic Development – Action Fund Grant

  Davidson, D.

  1/12/17 → 31/07/19

  Project: University Awarded Project Funding

• In situ macrophage phenotyping in ANCA-positive vasculitis in human biopsies

  Prost, S., Bellamy, C. & Kluth, D.

  UK-based charities

  1/09/17 → 31/08/21

  Project: Research

• In situ immunophenotyping and identification of macrophage subpopulations critical for bladder cancer growth and metastasis

  Prost, S., Arends, M., Brunton, V., Langdon, S. & Valanciute, A.

  Non-EU-based charities, UK-based charities

  1/09/17 → 31/08/22

  Project: Research

• The Boris Family Foundation Research Grant

  Davidson, D.

  1/09/17 → 31/08/20

  Project: Research Collaboration with external organisation

  • family 100%

• RESPIRE: Exploiting IT to Reduce Morbidity and Mortality from Asthma, COPD, Bacterial Pneumonia, Influenza, and RSV Infection in Low- and Middle-Income Countries

  Schwarze, J.

  Other

  1/08/17 → 30/09/22

  Project: Research

• RESPIRE: Exploiting IT to Reduce Morbidity and Mortality from Asthma, COPD, Bacterial Pneumonia, Influenza and RSV Infection in Low- and Middle-Income Countries

  Dockrell, D., Bogaert, D., Schwarze, J. & Whyte, M.

  Other

  1/08/17 → 30/09/22

  Project: Research

• BiomArker-guided Duration of Antibiotic treatment in hospitalised PaTients with moderate to severe Sepsis ¿¿¿ (ADAPT Sepsis)

  Lone, N. & Walsh, T.

  Other

  1/05/17 → 30/04/21

  Project: Research

• Proteus Participation in CARB-X

  Walsh, T., Dhaliwal, K. & Haslett, C.

  Non-EU other

  1/04/17 → 31/07/19

  Project: Research

  • Bacteria 100%
  • Screening 83%
  • Tissue 76%
  • Lasers 72%
  • Probe 54%

• Sedation and Weaning in Children (The SANDWICH Trial)

  Walsh, T.

  Other

  1/04/17 → 31/03/20

  Project: Research

• Inflammatory mechanisms to suppress Treg cell function in cancer

  Anderton, S. & Serrels, A.

  UK-based charities

  1/11/16 → 30/04/20

  Project: Research

  • Focal Adhesion Protein-Tyrosine Kinases 100%
  • Interleukin-33 54%
  • Phosphotransferase Inhibitor 50%
  • Immune Evasion 50%
  • Gene Regulatory Networks 43%

• Understanding macrophage phenotypes in normal and pathological healing: harnessing pro-resolving pathways to drive repair

  Cash, J. & Whyte, M.

  UK-based charities

  31/10/16 → 28/09/22

  Project: Research

• The Role of Tissue-resident Hepatic Macrophages in the Resolution of Chronic Liver Injury

  Ramachandran, P.

  MRC

  25/07/16 → 24/07/20

  Project: Research

  • Liver Cirrhosis 100%
  • Stellate Crystal 87%
  • macrophages 77%
  • Phagocytic 72%
  • Complement Receptors 71%

• The European Research Collaboration for Children's Interstitial Lung Disease (ChILDEU)

  Cunningham, S. & Cunningham, S.

  EU other

  1/06/16 → 31/05/19

  Project: Research

• ECAT Fellowship Catherine Davidson: Effects of FAK signalling on induction of Th17 cells in the tumour microenvironment.

  Serrels, A.

  UK-based charities

  1/08/15 → 31/07/18

  Project: Research

  • Immune Evasion 100%
  • Antigen Presentation 86%
  • Pancreatic Neoplasms 75%
  • Adenocarcinoma 62%
  • T-Lymphocytes 18%

• Scottish Healthcare Associated Infection Prevention Institute (SHAIPI)

  Walsh, T.

  Other

  1/04/15 → 31/03/20

  Project: Research

• SELEX Pilot: LASER Assisted Staphyloccal ERadication prior to orthopaedic implantation surgery (LASER Study)

  Walsh, T., Simpson, H. & Smith, L.

  UK industry, commerce and public corporations

  1/02/15 → 31/10/19

  Project: Research

• Implementing and evaluating Liver Multiscan MRI in rodent liver disease models

  Fallowfield, J., Jansen, M. & McDonald, N.

  31/01/15 → 31/07/15

  Project: Research Collaboration with external organisation

  • disease models 100%
  • liver diseases 97%
  • fibrosis 90%
  • rodents 61%
  • liver cirrhosis 52%

• Non-invasive assessment of haemodynamic response to beta-blockers using magnetic resonance imaging in patients with portal hypertension

  Fallowfield, J., Semple, S., Lilburn, D., Macnaught, G., McDonald, N. & Lachlan, N.

  1/01/15 → 1/01/16

  Project: University Awarded Project Funding

  • Portal Hypertension 100%
  • Propranolol 90%
  • Pharmaceutical Preparations 74%
  • Carvedilol 61%
  • Precision Medicine 48%

• Interactive Multimedia Public engagement projects for INFLAMMATION Research

  Davidson, D.

  1/01/15 → 31/12/15

  Project: University Awarded Project Funding

• R83382 Biomarker-based cellular analysis to predict stages of infection and sepsis

  Walsh, T.

  UK industry, commerce and public corporations

  1/11/14 → 31/10/16

  Project: Research

• Assessment of immunomodulatory compounds in driving M1 to M2 microglia macrophage activation switch in models of myelin injury and repair

  Miron, V.

  BBSRC

  1/10/14 → 30/09/18

  Project: Research

  • Remyelination 100%
  • Central Nervous System 83%
  • Necroptosis 79%
  • Immunomodulation 65%
  • Regeneration 59%

• Full Proposal - Ulipristal acetate versus conventional management of heavy menstrual bleeding (HMB; including uterine fibroids): a randomised controlled trial and exploration of mechanism of action (UCON trial)

  Critchley, H., Bhattacharya, S., Clark, T. J., Hapangama, D., Jane, D., Lee, M., Lumsden, M. A., Nicolls, E., Roberts, N. & Semple, S.

  UK central government bodies/local authorities, health and hospital authorities

  1/10/14 → 31/10/21

  Project: Research

  • Pregnancy Outcome 100%
  • Infertility 92%
  • Obstetrics 90%
  • Assisted Reproductive Techniques 60%
  • Placenta 46%

• Investigation of myofibroblast alpha-v integrins as an anti-fibrotic target in biliary atresia

  Henderson, N.

  UK-based charities

  1/10/14 → 30/09/17

  Project: Research

• Ahsan Akram - Scottish Alliance Framework Agreement

  Frame, M., Ball, K., Brunton, V. & Haslett, C.

  UK industry, commerce and public corporations

  1/09/14 → 31/07/17

  Project: Research

• An intravital imaging approach to elucidate novel mechanisms of organ fibrosis and repair

  Henderson, N.

  UK-based charities

  1/08/14 → 31/01/20

  Project: Research

  • Integrins 100%
  • Hepatic Stellate Cells 72%
  • Fibrosis 65%
  • Endothelial Cells 59%
  • Liver 54%

• Pro-oncogenic roles of the Tyro3/Axl/Mer receptor tyrosine kinase axis in non-Hodgkin's B-lymphoma

  Gregory, C. & Dransfield, I.

  UK-based charities

  1/08/14 → 31/07/18

  Project: Research

  • c-Mer Tyrosine Kinase 100%
  • B-Cell Lymphoma 57%
  • Macrophages 38%
  • Lymphoma 28%
  • Neoplasms 17%

• The parameters of tissue resident macrophage autonomy

  Jenkins, S.

  MRC

  1/07/14 → 30/06/17

  Project: Research

  • Macrophages 100%
  • macrophages 68%
  • Early Growth Response Protein 2 54%
  • Peritoneal Macrophages 42%
  • Monocytes 39%

• Reprogramming Alveolar Macrophages in IPF

  Marwick, J., Hirani, N. & Rossi, A.

  UK central government bodies/local authorities, health and hospital authorities

  1/07/14 → 30/06/16

  Project: Research