College of Medicine and Veterinary Medicine

Ostinelli, E. G., Chiocchia, V., Macleod, M., Browning, M., Harmer, C., Siafis, S., Stansfield, C., Friedrich, C., Wright, S., Chikaura, T., Milligan, L., Thomas, J., Moreno, C., Furukawa, T. A., Seedat, S., Potts, J., Salanti, G., Cipriani, A. & GALENOS team, 5 Oct 2023, p. 425, (Wellcome Open Research).

Research output: Working paper

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The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection: Functional characterisation of the murine meninges during chronic infections

Quintana, J. F., Sinton, M. C., Chandrasegaran, P., Dubey, L. K., Ogunsola, J., Samman, M. A., Haley, M. J., McConnell, G., Swar, N-R. K., Ngoyi, D. M., Mabbott, N. & MacLeod, A., 2 May 2023, (E-pub ahead of print) bioRxiv, at Cold Spring Harbor Laboratory, p. 1-62, 61 p. (bioRxiv).

Research output: Working paper

Open Access

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Assessment of long-term trends in genetic mean and variance after the introduction of genomic selection in layers: a simulation study

Pocrnic, I., Obsteter, J., Gaynor, C., Wolc, A. & Gorjanc, G., 21 Feb 2023, bioRxiv, at Cold Spring Harbor Laboratory.

Research output: Working paper

Open Access

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2022

Covid-19 monitoring in Scottish wastewater: Lessons Learned Review

Fletcher, I. & Lyall, C., 20 Oct 2022, (Unpublished) p. 1-17, 40 p.

Research output: Working paper

A divide-and-conquer approach for genomic prediction in rubber tree using machine learning

Aono, A. H., Francisco, F. R., Souza, L. M., Gonçalves, P. D. S., Scaloppi, E. J., Guen, V. L., Fritsche-Neto, R., Gorjanc, G., Quiles, M. G. & de Souza, A. P., 31 Mar 2022, bioRxiv, (bioRxiv).

Research output: Working paper

Open Access

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Multiplexed Label-Free Biomarker Detection by Targeted Disassembly of Variable-Length DNA Payload Chains

Aquilina, M. & Dunn, K., 27 Mar 2022, bioRxiv, at Cold Spring Harbor Laboratory, 35 p.

Research output: Working paper

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Genomic prediction with whole-genome sequence data in intensely selected pig lines

Ros-Freixedes, R., Johnsson, M., Chen, C-Y., Valente, B. D., Herring, W. O., Gorjanc, G. & Hickey, J. M., 5 Feb 2022, bioRxiv, 50 p. (bioRxiv).

Research output: Working paper

Open Access

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A multi-part strategy for introgression of exotic germplasm into elite plant breeding programs using genomic selection

Breider, I., Gaynor, R., Gorjanc, G., Thorn, S., Pandey, M. K., Varshney, R. K. & Hickey, J., 12 Jan 2022, (E-pub ahead of print) Research Square .

Research output: Working paper

Open Access

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Stem cell-derived macrophages as a new platform for studying host-pathogen interactions in livestock

Meek, S., Watson, T., Eory, L., McFarlane, G., Wynne, F. J., McCleary, S., Dunn, L. E. M., Charlton, E., Criag, C., Shih, B., Regan, T., Taylor, R., Sutherland, L., Gossner, A., Chintoan-Uta, C., Fletcher, S., Beard, P., Hassan, M., Grey, F., Hope, J., & 16 othersStevens, M., Nowak-Imialek, M., Niemann, H., Ross, P. J., Tait-Burkard, C., Brown, S., Lefevre, L., Thomson, G., McColl, B. W., Lawrence, A. B., Archibald, A., Steinbach, F., Crooke, H. R., Gao, X., Liu, P. & Burdon, T., 10 Jan 2022, bioRxiv, at Cold Spring Harbor Laboratory.

Research output: Working paper

Open Access

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2021

A study of the effectiveness of a detergent-based California mastitis test (CMT), using Ethiopian and Nigerian domestic detergents, for the detection of high somatic cell counts in milk and their reliability compared to the commercial UK CMT

Rust, J. D., Christian, M. J., Vance, C., Bolajoko, M. B., Wong, J., Suarez Martinez, J., Allan, F. & Peters, A., 20 Sept 2021, (E-pub ahead of print) Gates Open Research.

Research output: Working paper

Open Access

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Foot-and-mouth disease virus localisation on follicular dendritic cells and sustained induction of neutralising antibodies is dependent on binding to complement receptors (CR2/CR1)

Gordon, L., Mabbott, N., Wells, J., Kulik, L., Juleff, N., Charleston, B. & Perez-Martin, E., 8 Sept 2021, bioRxiv, at Cold Spring Harbor Laboratory.

Research output: Working paper

Open Access

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Efficient ancestry and mutation simulation with msprime 1.0

Baumdicker, F., Bisschop, G., Goldstein, D., Gower, G., Ragsdale, A. P., Tsambos, G., Zhu, S., Eldon, B., Ellerman, C. E., Galloway, J. G., Gladstein, A. L., Gorjanc, G., Guo, B., Jeffery, B., Kretzschmar, W. W., Lohse, K., Matschiner, M., Nelson, D., Pope, N. S., Quinto-Cortés, C. D., & 12 othersRodrigues, M. F., Saunack, K., Sellinger, T., Thornton, K., van Kemenade, H., Wohns, A. W., Wong, H. Y., Gravel, S., Kern, A. D., Koskela, J., Ralph, P. L. & Kelleher, J., 1 Sept 2021, bioRxiv, at Cold Spring Harbor Laboratory, (bioRxiv).

Research output: Working paper

Open Access

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Mena regulates the LINC complex to control actin–nuclear lamina associations, trans-nuclear membrane signalling and cancer gene expression

Chee, F. L. M., Beernaert, B., Loftus, A., Kumar, Y., Griffith, B. G. C., Wills, J. C., Wheeler, A. P., Armstrong, J. D., Parsons, M., Leigh, I. M., Proby, C. M., Kriegsheim, A. V., Bickmore, W. A., Frame, M. C. & Byron, A., 31 Aug 2021, bioRxiv.

Research output: Working paper

The SARS-CoV-2 Alpha variant causes increased clinical severity of disease

Pascall, D. J., Mollett, G., Blacow, R., Bulteel, N., Campbell, R., Campbell, A., Clifford, S., Davis, C., Da Silva Filipe, A., Fjodorova, L., Forrester, R., Goldstein, E., Gunson, R., Haughney, J., Holden, M. T. G., Honour, P., Hughes, J., James, E., Lewis, T., Lycett, S., & 8 othersMcHugh, M., Onishi, Y., Parcell, B., Robertson, D. L., Sakka, N. E., Shabaan, S., Shepherd, J. G. & Smollett, K., 24 Aug 2021, (E-pub ahead of print) medRxiv, (medRxiv).

Research output: Working paper

Open Access

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Secreted SARS-CoV-2 ORF8 modulates the cytokine expression profile of human macrophages

Kriplani, N., Clohisey, S., Fonseca, S., Fletcher, S., Lee, H-M., Ashworth, J., Kurian, D., Lycett, S. J., Tait-Burkard, C., Baillie, J. K., Woolhouse, M. E. J., Carding, S. R., Stewart, J. P. & Digard, P., 18 Aug 2021, (E-pub ahead of print) bioRxiv, at Cold Spring Harbor Laboratory.

Research output: Working paper

Open Access

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A type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS

Reyes, L., Sanchez Garcia, M. A., Morrison, T., Howden, A. J. M., Watts, E. R., Arienti, S., Sadiku, P., Coelho, P., Mirchandani, A. S., Zhang, A., Hope, D., Clark, S. K., Singleton, J., Johnston, S., Grecian, R., Poon, A. S., McNamara, S., Harper, I., Fourman, M. H., Brenes, A. J., & 14 othersPathak, S., Lloyd, A., Rodriguez Blanco, G., von Kriegsheim, A., Ghesquiere, B., Vermaelen, W., Cologna, C. T., Dhaliwal, K., Hirani, N., Dockrell, D. H., Whyte, M. K. B., Griffith, D. M., Cantrell, D. & Walmsley, S. R., 25 Jun 2021, (E-pub ahead of print) Wellcome Open Research, (wellcome Open Research).

Research output: Working paper

Open Access

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DTOceanPlus D8.4 Developing Ocean Energy standards for Business management models in Ocean Energy

Tunga, I., Yates, M., Vyas, A., Briggs, S., Elliott, T., Eraut, N., Ruiz-Minguela, P., Salcedo, F., Noble, D. R., Hodges, J., Marques, M. I. & Connor, G., 25 Jun 2021, DTOceanPlus Consortium, 155 p.

Research output: Working paper

Parental methyl-enhanced diet and in ovo corticosterone affect first generation Japanese quail (Coturnix coturnix japonica) development, behaviour and stress response.

Boulton, K., Perez, J., Wilkinson, T., Hogan, K., Homer, N. Z. M., Robert, C., Smith, J., Meddle, S., Dunn, I., Watson, K. & Wilson, P., 3 May 2021, Research Square .

Research output: Working paper

Open Access

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A gene drive does not spread easily in populations of the honey bee parasite Varroa destructor

Faber, N., Meiborg, Y., McFarlane, G., Gorjanc, G. & Harpur, B. A., 30 Apr 2021, bioRxiv, at Cold Spring Harbor Laboratory.

Research output: Working paper

Open Access

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Student views and experiences of a symptomatic COVID-19 testing at the University of Edinburgh

Street, A., Baxter, M. S., Christison, S., Bevan, I. & Bauld, L., 2 Apr 2021, p. 1-35, 35 p.

Research output: Working paper

Open Access

Structural basis for the coiled-coil architecture of human CtIP

Morton, C. R., Rzechorzek, N. J., Maman, J. D., Kuramochi, M., Sekiguchi, H., Rambo, R., Sasaki, Y. C., Davies, O. R. & Pellegrini, L., 5 Mar 2021, bioRxiv, at Cold Spring Harbor Laboratory.

Research output: Working paper

Effectiveness of First Dose of COVID-19 Vaccines Against Hospital Admissions in Scotland: National Prospective Cohort Study of 5.4 Million People

Vasileiou, E., Bradley, D., Chuter, A., de Lusignan, S., Docherty, A., Ford, D., Hobbs, R., Joy, M., Katikireddi, S. V., Marple, J., McCowan, C., Simpson, C. R., McGagh, D., McMenamin, J., Moore, E., Murray, J-L. K., Pan, J., Ritchie, L., Shah, S. A., Stock, S., & 12 othersTorabi, F., Tsang, R. S. M., Robertson, C., Wood, R., Woolhouse, M., Sheikh, A., Shi, T., Kerr, S., Agrawal, U., Akbari, A., Bedston, S. & Beggs, J., 19 Feb 2021, Social Science Research Network (SSRN), (THELANCET-D-21-01335).

Research output: Working paper

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Diurnal brain temperature rhythms and mortality after brain injury: a prospective and retrospective cohort study

Rzechorzek, N., Thrippleton, M., Chappell, F. M., Mair, G., Ercole, A., Cabeleira, M., Rhodes, J., Marshall, I. & O'Neill, J. S., 27 Jan 2021.

Research output: Working paper

Open Access

Epidemic waves of COVID-19 in Scotland: a genomic perspective on the impact of the introduction and relaxation of lockdown on SARS-CoV-2

Lycett, S. J., Hughes, J., McHugh, M. P., Filipe, A. D. S., Dewar, R., Lu, L., Doherty, T., Shepherd, A., Inward, R., Rossi, G., Balaz, D., Kao, R. R., Rooke, S., Cotton, S., Gallagher, M. D., Lopez, C. B., O’Toole, Á., Scher, E., Hill, V., McCrone, J. T., & 34 othersColquhoun, R. M., Jackson, B., Williams, T. C., Williamson, K. A., Johnson, N., Smollett, K., Mair, D., Carmichael, S., Tong, L., Nichols, J., Brunker, K., Shepherd, J. G., Li, K., Aranday-Cortes, E., Parr, Y. A., Broos, A., Nomikou, K., McDonald, S. E., Niebel, M., Asamaphan, P., Starinskij, I., Jesudason, N., Shah, R., Sreenu, V. B., Stanton, T., Shaaban, S., MacLean, A., Woolhouse, M., Gunson, R., Templeton, K., Thomson, E. C., Rambaut, A., Holden, M. T. G. & Robertson, D. L., 20 Jan 2021, Cold Spring Harbor Laboratory Press.

Research output: Working paper

Open Access

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The cost of asking 'say that again?': a social capital theory view into how lecture recording supports widening participation

MacKay, J. R. D., Nordmann, E., Murray, L., Browitt, A., university of glasgow, M. & Hutchison, J., 7 Jan 2021, EdArXiv, 17 p.

Research output: Working paper

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Complete microglia deficiency accelerates prion disease without enhancing CNS prion accumulation

Bradford, B., McGuire, L., Hume, D. A., Pridans, C. & Mabbott, N., 6 Jan 2021, bioRxiv, at Cold Spring Harbor Laboratory, (Cell Reports).

Research output: Working paper

Open Access

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Lights, camera, active! Appreciation of active learning predicts positive attitudes towards lecture capture

Nordmann, E., Clark, A., Spaeth, E. & MacKay, J. R. D., 5 Jan 2021, PsyArXiv.

Research output: Working paper

Open Access

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2020

Age Related Changes in the Circulating Leukocyte Transcriptome in Dairy Cows

Buggiotti, L., Cheng, Z., Salavati, M. & Wathes, D. C., 28 Dec 2020, Research Square .

Research output: Working paper

A configurable model of the synaptic proteome reveals the molecular mechanisms of disease co-morbidity

Sorokina, O., Mclean, C., Croning, M. DR., Heil, K. F., Wysocka, E., He, X., Sterratt, D., Grant, S. GN., Simpson, T. I. & Armstrong, J. D., 29 Oct 2020, bioRxiv.

Research output: Working paper

Open Access

Scaling Systematic Literature Reviews with Machine Learning Pipelines

Goldfarb-Tarrant, S., Robertson, A., Lazic, J., Tsouloufi, T., Donnison, L. & Smyth, K., 9 Oct 2020, arXiv.org.

Research output: Working paper

Genetic mechanisms of critical illness in Covid-19

Pairo-Castineira, E., Clohisey, S., Klaric, L., Bretherick, A. D., Rawlik, K., Parkinson, N., Pasko, D., Walker, S., Richmond, A., Fourman, M. H., Law, A., Furniss, J., Gountouna, E., Wrobel, N., Russell, C. D., Moutsianas, L., Wang, B., Meynert, A. M., Yang, Z., Zhai, R., & 39 othersZheng, C., Griffith, F., Oosthuyzen, W., Shih, B., Keating, S., Zechner, M., Haley, C., Porteus, D. J., Hayward, C., Knight, J., Summers, C., Shankar-Hari, M., Turtle, L., Ho, A., Hinds, C., Horby, P., Nichol, A., Maslove, D. M., Ling, L., Klenerman, P., McAuley, D. F., Montgomery, H., Walsh, T. S., The GenOMICC Investigators, The ISARIC4C Investigators, The Covid-19 Human Genetics Initiative, Shen, X., Rowan, K., Fawkes, A., Murphy, L., Ponting, C. P., Tenesa, A., Caulfield, M., Scott, R., Openshaw, P. J. M., Semple, M. G., Vitart, V., Wilson, J. F. & Baillie, J. K., 25 Sept 2020, medRxiv.

Research output: Working paper

Primary sex determination in chickens depends on DMRT1 dosage, but gonadal sex does not determine secondary sexual characteristics in adult birds

Ioannidis, J., Taylor, G., Zhao, D., Liu, L., Idoko-Akoh, A., Gong, D., Lovell-Badge, R., Guioli, S., McGrew, M. & Clinton, M., 19 Sept 2020, bioRxiv, at Cold Spring Harbor Laboratory.

Research output: Working paper

Open Access

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Ecological niche adaptation of a bacterial pathogen associated with reduced zoonotic potential

Kirkwood, M., Vohra, P., Bawn, M., Thilliez, G., Pye, H., Tanner, J., Chintoan-Uta, C., Branchu, P., Petrovska, L., Dallman, T., Hall, N., Stevens, M. & Kingsley, R. A., 9 Sept 2020, bioRxiv, at Cold Spring Harbor Laboratory.

Research output: Working paper

Open Access

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