Datasets
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Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease - RNAseq data
Spires-Jones, T. (Creator) & Dando, O. (Creator), EMBL's European Bioinformatics Institute, 2019
https://www.ebi.ac.uk/biostudies/arrayexpress/studies/E-MTAB-7856
Dataset
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Temporal analysis of RNA turnover in Interferon Gamma treated bone marrow-derived macrophages
Robertson, K. (Creator) & Ghazal, P. (Creator), Edinburgh DataShare, 21 Jun 2016
DOI: 10.7488/ds/1428
Dataset
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FMR1 knock-out mouse EEG recordings
Oren, I. (Creator), Brown, R. (Creator) & Osterweil, E. (Owner), Edinburgh DataVault, 2018
DOI: 10.7488/e79d76fe-fd66-4cc6-ad4a-2b71ff3c607a
Dataset
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C57Bl6/J mouse EEG recordings
Oren, I. (Creator), Brown, R. (Creator), Osterweil, E. (Owner) & Meijer, D. (Owner), Edinburgh DataVault, 2018
DOI: 10.7488/9709d7b4-84c3-467f-b538-af50cc520892
Dataset
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APP NL/F - 1 year rodent EEG and video recordings. Cerebellum reference
Oren, I. (Creator) & Brown, R. (Creator), Edinburgh DataVault, 22 Jun 2018
DOI: 10.7488/a1dab399-eeb6-4c5d-934e-c702f4e3f6b9
Dataset
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APP NL/F - 8 month rodent EEG and video recordings
Oren, I. (Creator) & Brown, R. (Owner), Edinburgh DataVault, 22 Jun 2018
DOI: 10.7488/839bb0e2-2927-4749-83c5-faba98c2ccc6
Dataset
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APP NL/F - 1 year rodent EEG and video recordings. Cerebellum reference. Donepezil administration
Oren, I. (Creator) & Brown, R. (Creator), Edinburgh DataVault, 29 Jun 2018
DOI: 10.7488/0fbe4409-56ec-42ec-807f-8234541dc239
Dataset
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Synthetic cell-based patterning systems and their applications in stem cell differentiation
Glykofrydis, F. (Owner), Popravko, A. (Creator), Dzierzak, E. (Owner), Davies, J. (Owner), Romanowski, A. (Data Manager) & Zielinski, T. (Data Manager), Edinburgh DataVault, 30 Jan 2021
DOI: 10.7488/387d2274-5678-4626-a138-732ba80a767c
Dataset
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A system for in vivo ablation of MeCP2-deficient neurons in the Rett Syndrome mouse model
Paton, K. (Owner), Selfridge, J. (Creator), Guy, J. (Researcher), Connelly, J. (Researcher), Waterfall, M. (Researcher), Kelly, D. (Researcher), Davies, J. (Supervisor), Smith, A. (Supervisor), Rosser, S. (Supervisor), Bird, A. (Owner), Romanowski, A. (Data Manager), Zielinski, T. (Data Manager) & Paton, K. (Owner), Edinburgh DataVault, 30 Apr 2021
DOI: 10.7488/139e57b5-25ed-4ad2-b9bc-d323305ede21
Dataset
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LTP data from MAPT-AD experiment and APP/PS1 experiment
Oren, I. (Creator) & Spires-Jones, T. (Owner), Edinburgh DataVault, 2018
DOI: 10.7488/bacc399c-0d03-41d6-92b9-a180d6dc7b84, https://datavault.ed.ac.uk/
Dataset
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APP NL/F - 1 year rodent EEG and video recordings. Cortex reference
Oren, I. (Creator) & Brown, R. (Creator), Edinburgh DataVault, 29 Jun 2018
DOI: 10.7488/fc6ff337-6d54-4166-926c-1fa7317a9cb5
Dataset
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J20 rodent EEG and video recordings
Oren, I. (Creator) & Brown, R. (Creator), Edinburgh DataVault, 2018
DOI: 10.7488/e2c30baf-823e-4ec2-a104-013549da58bc
Dataset
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LGI2 DataVault data
Oren, I. (Creator), Meijer, D. (Owner) & Brown, R. (Creator), Edinburgh DataVault, 2018
DOI: 10.7488/8b0ca52c-f086-40bb-af2a-a551f6bc00f4
Dataset
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Temporal analysis of RNA turnover in Interferon Gamma treated bone marrow-derived macrophages
Robertson, K. (Creator) & Ghazal, P. (Creator), National Center for Biotechnology Information (Gene Expression Omnibus), 7 Mar 2016
DOI: 10.7488/210e1946-2590-49ec-8a1d-a31667d1b3bb, https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE63290 and one more link, http://10.1371/journal.pbio.1002364 (show fewer)
Dataset
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Spires-Jones archived raw lab data 2013-2018
Spires-Jones, T. (Creator) & Spires-Jones, T. (Data Manager), Edinburgh DataVault, 1 Sept 2018
Dataset
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Probiotic Bacillus subtilis Protects against a-Synuclein Aggregation in C. elegans (Goya ME et al., Cell Reports, 2020)
Goya, E. (Creator) & Romanowski, A. (Depositor), The University of Edinburgh, 10 Aug 2020
https://publicomero.bio.ed.ac.uk/webclient/?show=project-58
Dataset
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E-MTAB-8164 - RNAseq of young adult C. elegans animals fed on three different bacterial diets, E. coli OP50, B. subtilis PXN21 and a mixture of both
Goya, E. (Creator), Romanowski, A. (Depositor) & Doitsidou, M. (Project Leader), ArrayExpress Archive of Functional Genomics Data, 14 Jan 2020
https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-8164
Dataset
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Activity-induced filopodia form at the presynapse and enclose SV fusion.
Ivanova, D. (Creator), Edinburgh DataShare, 20 Aug 2024
DOI: 10.7488/ds/7793
Dataset
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Data for re-evaluation of the causes of variation among mouse aggregation chimaeras
West, J. (Creator), MacKay, G. E. (Creator), Flockhart, J. H. (Creator), Keighren, M. A. (Creator), Everett, C. A. (Creator) & Tang, P. (Creator), Edinburgh DataShare, 31 May 2019
DOI: 10.7488/ds/2540
Dataset
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Whole slide images of armadillo liver from M.leprae dataset
Kendall, T. (Creator) & Rambukkana, A. (Creator), Edinburgh DataShare, 31 Mar 2023
DOI: 10.7488/ds/3147
Dataset
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High and asymmetric somato-dendritic coupling of V1 layer 5 neurons independent of visual stimulation and locomotion
Rochefort, N. (Creator), Padamsey, Z. (Creator) & Francioni, V. (Creator), Edinburgh DataShare, 9 Apr 2021
DOI: 10.7488/ds/3013, https://elifesciences.org/articles/49145
Dataset
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Data supporting Davies & Beadman (2025) "Self-organization, error-correction and homeorhesis in renal development"
Beadman, R. (Creator) & Davies, J. (Creator), Edinburgh DataShare, 16 Oct 2024
DOI: 10.7488/ds/7819
Dataset
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Macropinocyosis filopodia
Cousin, M. (Creator), Edinburgh DataShare, 11 Jan 2022
DOI: 10.7488/ds/3273
Dataset
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Inter- and intra-animal variation in the integrative properties of stellate cells in the medial entorhinal cortex
Pastoll, H. (Creator), Garden, D. (Creator) & Nolan, M. (Creator), Edinburgh DataShare, 7 Feb 2020
DOI: 10.7488/ds/2765, https://github.com/MattNolanLab
Dataset
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Data: Extrusion Bioprinting: Meeting the Promise of the Human Tissue Biofabrication
Holland, I. (Creator), Edinburgh DataShare, 4 Feb 2025
DOI: 10.7488/ds/7869
Dataset
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Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer's disease - TEM data
Spires-Jones, T. (Creator), Edinburgh DataShare, 17 Aug 2018
DOI: 10.7488/ds/2417
Dataset
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Image analysis macros for array tomography
Spires-Jones, T. (Creator), Edinburgh DataShare, 24 Jul 2019
DOI: 10.7488/ds/2592, https://doi.org/10.1101/393405
Dataset
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Data from paper: Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer’s disease
Spires-Jones, T. (Creator), Edinburgh DataShare, 23 Feb 2022
DOI: 10.7488/ds/3412, https://doi.org/10.1101/2021.11.24.469829
Dataset
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Data from paper: Predictive blood biomarkers and brain changes associated with age-related cognitive decline
Spires-Jones, T. (Creator), Edinburgh DataShare, 22 Mar 2023
DOI: 10.7488/ds/3826
Dataset
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Array tomography image analysis macros 2024
Spires-Jones, T. (Creator), Edinburgh DataShare, 13 Feb 2025
DOI: 10.7488/ds/7875
Dataset
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Spatial computational model of calcium signalling in the dendritic spines and its relation to Alzheimer's Disease
Arora, S. (Creator) & Stefan, M. (Creator), Edinburgh DataShare, 2 Aug 2018
DOI: 10.7488/ds/2400
Dataset
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Simplified biochemical model of synaptic plasticity, extended with Calcium-Induced Calcium Release
Diamantopoulos, M. (Creator), Herpich, G. (Creator), Xie, Y. (Creator) & Stefan, M. (Creator), Edinburgh DataShare, 6 Aug 2018
DOI: 10.7488/ds/2404
Dataset
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Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer’s disease
Catalano, S. M. (Creator), Dando, O. (Creator), Hamby, M. E. (Creator), Izzo, N. J. (Creator), Smith, C. (Creator), Spires-Jones, T. (Creator), Colom Cadena, M. (Creator), Toombs, J. (Creator), Simzer, E. M. (Creator), Tulloch, J. (Creator), Jackson, R. (Creator), Catterson, J. (Creator), Rose, J. (Creator), Waybright, L. (Creator), Caggiano, A. O. (Creator), Davies, C. (Creator), Hooley, M. (Creator), Dunnett, S. (Creator), Tempelaar, R. (Creator) & Tzioras, M. (Creator), Edinburgh DataShare, 9 Jan 2024
DOI: 10.7488/ds/7664, https://www.biorxiv.org/content/10.1101/2021.02.01.428238v2
Dataset
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Inhibitory synapse loss and accumulation of amyloid beta in inhibitory presynaptic terminals in Alzheimer’s disease - Kurucu et al
Spires-Jones, T. (Creator), Edinburgh DataShare, 26 Jul 2021
DOI: 10.7488/ds/3098, https://doi.org/10.1111/ene.15043
Dataset
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An Investigation of Synaptic Dysfunction in Alzheimer’s Disease - Chapter 5 - Thresholding Macros
Jackson, R. (Creator), Edinburgh DataShare, 5 Sept 2017
DOI: 10.7488/ds/2135
Dataset
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Spatial representation by ramping activity of neurons in the retrohippocampal cortex
Clark, H. (Creator), Nolan, M. (Creator), Tam, T. (Creator), Hua, J. (Creator) & Tennant, S. (Creator), Edinburgh DataShare, 30 Aug 2022
DOI: 10.7488/ds/3515, https://www.biorxiv.org/content/10.1101/2021.03.15.435518v3
Dataset
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Human tau increases amyloid beta plaque size but not amyloid beta-mediated synapse loss in a novel mouse model of Alzheimer’s disease: Data set from Jackson et al 2016 EJN
Spires-Jones, T. (Creator) & Jackson, R. (Creator), Edinburgh DataShare, 28 Oct 2016
DOI: 10.7488/ds/1507
Dataset
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Fan cells in lateral entorhinal cortex directly influence medial entorhinal cortex through synaptic connections in layer 1
Vandrey, B. (Creator), Edinburgh DataShare, 12 Dec 2022
DOI: 10.7488/ds/3787, https://www.biorxiv.org/content/10.1101/2022.08.25.505296v1
Dataset
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Motyl AAL, et al. (2020). Pre-symptomatic developmental phenotypes in Spinal Muscular Atrophy
MOTYL, A. (Creator), Gillingwater, T. (Creator) & Wishart, T. (Creator), Edinburgh DataShare, 3 Mar 2020
DOI: 10.7488/ds/2776
Dataset
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Data from: Automated single particle detection and tracking for large microscopy datasets
Wilson, R. S. (Creator), Yang, L. (Creator), Dun, A. (Creator), Smyth, A. M. (Creator), Duncan, R. R. (Creator), Rickman, C. (Creator) & Lu, W. (Creator), Dryad, 22 Apr 2016
DOI: 10.5061/dryad.6kg29, https://datadryad.org/stash/dataset/doi:10.5061/dryad.6kg29
Dataset
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Non-fibrillar oligomeric amyloid-β within synapses: Data set from publication Pickett et al 2016 J Alz Dis
Pickett, E. (Creator), Koffie, R. M. (Creator), Wegmann, S. (Creator), Henstridge, C. (Creator), Herrmann, A. (Creator), Colom-Cadena, M. (Creator), Lleo, A. (Creator), Kay, K. R. (Creator), Vaught, M. (Creator), Soberman, R. (Creator), Walsh, D. M. (Creator), Hyman, B. T. (Creator) & Spires-Jones, T. (Creator), Edinburgh DataShare, 3 Jun 2016
DOI: 10.7488/ds/1415
Dataset
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Whole blood mRNA expression profiling of host molecular networks in neonatal sepsis
Smith, C. (Creator), Ghazal, P. (Creator), Dickinson, P. (Creator), Craigon, M. (Creator), Forster, T. (Hosting Institution) & Ross, A. (Creator), National Center for Biotechnology Information (Gene Expression Omnibus), 12 Aug 2014
http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE25504
Dataset
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An Investigation of Synaptic Dysfunction in Alzheimer’s Disease - Chapter 3 - Thresholding Macros
Jackson, R. (Creator), Edinburgh DataShare, 5 Sept 2017
DOI: 10.7488/ds/2133
Dataset
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Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer’s disease - Data from 2017 Publication
Spires-Jones, T. (Creator) & Pickett, E. (Creator), Edinburgh DataShare, 6 Feb 2017
DOI: 10.7488/ds/1706, http://onlinelibrary.wiley.com/doi/10.1002/syn.21965/full
Dataset
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Temporal coupling of axonal calcium responses and filopodia formation
Ivanova, D. (Creator), Edinburgh DataShare, 20 Aug 2024
DOI: 10.7488/ds/7794
Dataset
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Proteomics datasets from Shorrock et al (UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy)
Gillingwater, T. (Creator), Edinburgh DataShare, 8 Aug 2018
DOI: 10.7488/ds/2405
Dataset
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Neocortex saves energy by reducing coding precision during food scarcity
Rochefort, N. (Creator), Padamsey, Z. (Creator) & Katsanevaki, D. (Creator), Edinburgh DataShare, 30 Nov 2021
DOI: 10.7488/ds/3214, https://doi.org/10.1016/j.neuron.2021.10.024
Dataset
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Figure 1 Gordon et al (2016) A fine balance of synaptophysin levels underlies efficient retrieval of synaptobrevin II to synaptic vesicles (PLOS ONE)
Cousin, M. (Creator) & Smillie, K. (Creator), Edinburgh DataShare, 15 Jan 2016
DOI: 10.7488/ds/1310
Dataset
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Neuronal signature of spatial decision-making during navigation by freely moving rats by using calcium imaging
Mitchell-Heggs, R. (Creator), Tse, D. (Creator), Schultz, S. R. (Creator), Morris, R. (Creator), Morris, R. (Creator) & Gobbo, F. (Creator), Edinburgh DataShare, 28 Oct 2022
DOI: 10.7488/ds/3774
Dataset
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Thesis Movies - 'Mechanisms of kidney vascularisation and the roles of macrophages in renal organogenesis'
Munro, D. (Creator), Edinburgh DataShare, 13 Aug 2018
DOI: 10.7488/ds/2413
Dataset