Deanery of Biomedical Sciences

Search results

• Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease - RNAseq data

  Spires-Jones, T. (Creator) & Dando, O. (Creator), EMBL's European Bioinformatics Institute, 2019

  https://www.ebi.ac.uk/biostudies/arrayexpress/studies/E-MTAB-7856

  Dataset

• Temporal analysis of RNA turnover in Interferon Gamma treated bone marrow-derived macrophages

  Robertson, K. (Creator) & Ghazal, P. (Creator), Edinburgh DataShare, 21 Jun 2016

  DOI: 10.7488/ds/1428

  Dataset

• FMR1 knock-out mouse EEG recordings

  Oren, I. (Creator), Brown, R. (Creator) & Osterweil, E. (Owner), Edinburgh DataVault, 2018

  DOI: 10.7488/e79d76fe-fd66-4cc6-ad4a-2b71ff3c607a

  Dataset

• C57Bl6/J mouse EEG recordings

  Oren, I. (Creator), Brown, R. (Creator), Osterweil, E. (Owner) & Meijer, D. (Owner), Edinburgh DataVault, 2018

  DOI: 10.7488/9709d7b4-84c3-467f-b538-af50cc520892

  Dataset

• APP NL/F - 1 year rodent EEG and video recordings. Cerebellum reference

  Oren, I. (Creator) & Brown, R. (Creator), Edinburgh DataVault, 22 Jun 2018

  DOI: 10.7488/a1dab399-eeb6-4c5d-934e-c702f4e3f6b9

  Dataset

• APP NL/F - 8 month rodent EEG and video recordings

  Oren, I. (Creator) & Brown, R. (Owner), Edinburgh DataVault, 22 Jun 2018

  DOI: 10.7488/839bb0e2-2927-4749-83c5-faba98c2ccc6

  Dataset

• APP NL/F - 1 year rodent EEG and video recordings. Cerebellum reference. Donepezil administration

  Oren, I. (Creator) & Brown, R. (Creator), Edinburgh DataVault, 29 Jun 2018

  DOI: 10.7488/0fbe4409-56ec-42ec-807f-8234541dc239

  Dataset

• Synthetic cell-based patterning systems and their applications in stem cell differentiation

  Glykofrydis, F. (Owner), Popravko, A. (Creator), Dzierzak, E. (Owner), Davies, J. (Owner), Romanowski, A. (Data Manager) & Zielinski, T. (Data Manager), Edinburgh DataVault, 30 Jan 2021

  DOI: 10.7488/387d2274-5678-4626-a138-732ba80a767c

  Dataset

• A system for in vivo ablation of MeCP2-deficient neurons in the Rett Syndrome mouse model

  Paton, K. (Owner), Selfridge, J. (Creator), Guy, J. (Researcher), Connelly, J. (Researcher), Waterfall, M. (Researcher), Kelly, D. (Researcher), Davies, J. (Supervisor), Smith, A. (Supervisor), Rosser, S. (Supervisor), Bird, A. (Owner), Romanowski, A. (Data Manager), Zielinski, T. (Data Manager) & Paton, K. (Owner), Edinburgh DataVault, 30 Apr 2021

  DOI: 10.7488/139e57b5-25ed-4ad2-b9bc-d323305ede21

  Dataset

• LTP data from MAPT-AD experiment and APP/PS1 experiment

  Oren, I. (Creator) & Spires-Jones, T. (Owner), Edinburgh DataVault, 2018

  DOI: 10.7488/bacc399c-0d03-41d6-92b9-a180d6dc7b84, https://datavault.ed.ac.uk/

  Dataset

• APP NL/F - 1 year rodent EEG and video recordings. Cortex reference

  Oren, I. (Creator) & Brown, R. (Creator), Edinburgh DataVault, 29 Jun 2018

  DOI: 10.7488/fc6ff337-6d54-4166-926c-1fa7317a9cb5

  Dataset

• J20 rodent EEG and video recordings

  Oren, I. (Creator) & Brown, R. (Creator), Edinburgh DataVault, 2018

  DOI: 10.7488/e2c30baf-823e-4ec2-a104-013549da58bc

  Dataset

• LGI2 DataVault data

  Oren, I. (Creator), Meijer, D. (Owner) & Brown, R. (Creator), Edinburgh DataVault, 2018

  DOI: 10.7488/8b0ca52c-f086-40bb-af2a-a551f6bc00f4

  Dataset

• Temporal analysis of RNA turnover in Interferon Gamma treated bone marrow-derived macrophages

  Robertson, K. (Creator) & Ghazal, P. (Creator), National Center for Biotechnology Information (Gene Expression Omnibus), 7 Mar 2016

  DOI: 10.7488/210e1946-2590-49ec-8a1d-a31667d1b3bb, https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE63290 and one more link, http://10.1371/journal.pbio.1002364 (show fewer)

  Dataset

• Spires-Jones archived raw lab data 2013-2018

  Spires-Jones, T. (Creator) & Spires-Jones, T. (Data Manager), Edinburgh DataVault, 1 Sept 2018

  https://datavault.ed.ac.uk/

  Dataset

• Probiotic Bacillus subtilis Protects against a-Synuclein Aggregation in C. elegans (Goya ME et al., Cell Reports, 2020)

  Goya, E. (Creator) & Romanowski, A. (Depositor), The University of Edinburgh, 10 Aug 2020

  https://publicomero.bio.ed.ac.uk/webclient/?show=project-58

  Dataset

• E-MTAB-8164 - RNAseq of young adult C. elegans animals fed on three different bacterial diets, E. coli OP50, B. subtilis PXN21 and a mixture of both

  Goya, E. (Creator), Romanowski, A. (Depositor) & Doitsidou, M. (Project Leader), ArrayExpress Archive of Functional Genomics Data, 14 Jan 2020

  https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-8164

  Dataset

• Activity-induced filopodia form at the presynapse and enclose SV fusion.

  Ivanova, D. (Creator), Edinburgh DataShare, 20 Aug 2024

  DOI: 10.7488/ds/7793

  Dataset

• Data for re-evaluation of the causes of variation among mouse aggregation chimaeras

  West, J. (Creator), MacKay, G. E. (Creator), Flockhart, J. H. (Creator), Keighren, M. A. (Creator), Everett, C. A. (Creator) & Tang, P. (Creator), Edinburgh DataShare, 31 May 2019

  DOI: 10.7488/ds/2540

  Dataset

• Whole slide images of armadillo liver from M.leprae dataset

  Kendall, T. (Creator) & Rambukkana, A. (Creator), Edinburgh DataShare, 31 Mar 2023

  DOI: 10.7488/ds/3147

  Dataset

• High and asymmetric somato-dendritic coupling of V1 layer 5 neurons independent of visual stimulation and locomotion

  Rochefort, N. (Creator), Padamsey, Z. (Creator) & Francioni, V. (Creator), Edinburgh DataShare, 9 Apr 2021

  DOI: 10.7488/ds/3013, https://elifesciences.org/articles/49145

  Dataset

• Data supporting Davies & Beadman (2025) "Self-organization, error-correction and homeorhesis in renal development"

  Beadman, R. (Creator) & Davies, J. (Creator), Edinburgh DataShare, 16 Oct 2024

  DOI: 10.7488/ds/7819

  Dataset

• Macropinocyosis filopodia

  Cousin, M. (Creator), Edinburgh DataShare, 11 Jan 2022

  DOI: 10.7488/ds/3273

  Dataset

• Inter- and intra-animal variation in the integrative properties of stellate cells in the medial entorhinal cortex

  Pastoll, H. (Creator), Garden, D. (Creator) & Nolan, M. (Creator), Edinburgh DataShare, 7 Feb 2020

  DOI: 10.7488/ds/2765, https://github.com/MattNolanLab

  Dataset

• Data: Extrusion Bioprinting: Meeting the Promise of the Human Tissue Biofabrication

  Holland, I. (Creator), Edinburgh DataShare, 4 Feb 2025

  DOI: 10.7488/ds/7869

  Dataset

• Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer's disease - TEM data

  Spires-Jones, T. (Creator), Edinburgh DataShare, 17 Aug 2018

  DOI: 10.7488/ds/2417

  Dataset

• Image analysis macros for array tomography

  Spires-Jones, T. (Creator), Edinburgh DataShare, 24 Jul 2019

  DOI: 10.7488/ds/2592, https://doi.org/10.1101/393405

  Dataset

• Data from paper: Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer’s disease

  Spires-Jones, T. (Creator), Edinburgh DataShare, 23 Feb 2022

  DOI: 10.7488/ds/3412, https://doi.org/10.1101/2021.11.24.469829

  Dataset

• Data from paper: Predictive blood biomarkers and brain changes associated with age-related cognitive decline

  Spires-Jones, T. (Creator), Edinburgh DataShare, 22 Mar 2023

  DOI: 10.7488/ds/3826

  Dataset

• Array tomography image analysis macros 2024

  Spires-Jones, T. (Creator), Edinburgh DataShare, 13 Feb 2025

  DOI: 10.7488/ds/7875

  Dataset

• Spatial computational model of calcium signalling in the dendritic spines and its relation to Alzheimer's Disease

  Arora, S. (Creator) & Stefan, M. (Creator), Edinburgh DataShare, 2 Aug 2018

  DOI: 10.7488/ds/2400

  Dataset

• Simplified biochemical model of synaptic plasticity, extended with Calcium-Induced Calcium Release

  Diamantopoulos, M. (Creator), Herpich, G. (Creator), Xie, Y. (Creator) & Stefan, M. (Creator), Edinburgh DataShare, 6 Aug 2018

  DOI: 10.7488/ds/2404

  Dataset

• Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer’s disease

  Catalano, S. M. (Creator), Dando, O. (Creator), Hamby, M. E. (Creator), Izzo, N. J. (Creator), Smith, C. (Creator), Spires-Jones, T. (Creator), Colom Cadena, M. (Creator), Toombs, J. (Creator), Simzer, E. M. (Creator), Tulloch, J. (Creator), Jackson, R. (Creator), Catterson, J. (Creator), Rose, J. (Creator), Waybright, L. (Creator), Caggiano, A. O. (Creator), Davies, C. (Creator), Hooley, M. (Creator), Dunnett, S. (Creator), Tempelaar, R. (Creator) & Tzioras, M. (Creator), Edinburgh DataShare, 9 Jan 2024

  DOI: 10.7488/ds/7664, https://www.biorxiv.org/content/10.1101/2021.02.01.428238v2

  Dataset

• Inhibitory synapse loss and accumulation of amyloid beta in inhibitory presynaptic terminals in Alzheimer’s disease - Kurucu et al

  Spires-Jones, T. (Creator), Edinburgh DataShare, 26 Jul 2021

  DOI: 10.7488/ds/3098, https://doi.org/10.1111/ene.15043

  Dataset

• An Investigation of Synaptic Dysfunction in Alzheimer’s Disease - Chapter 5 - Thresholding Macros

  Jackson, R. (Creator), Edinburgh DataShare, 5 Sept 2017

  DOI: 10.7488/ds/2135

  Dataset

• Spatial representation by ramping activity of neurons in the retrohippocampal cortex

  Clark, H. (Creator), Nolan, M. (Creator), Tam, T. (Creator), Hua, J. (Creator) & Tennant, S. (Creator), Edinburgh DataShare, 30 Aug 2022

  DOI: 10.7488/ds/3515, https://www.biorxiv.org/content/10.1101/2021.03.15.435518v3

  Dataset

• Human tau increases amyloid beta plaque size but not amyloid beta-mediated synapse loss in a novel mouse model of Alzheimer’s disease: Data set from Jackson et al 2016 EJN

  Spires-Jones, T. (Creator) & Jackson, R. (Creator), Edinburgh DataShare, 28 Oct 2016

  DOI: 10.7488/ds/1507

  Dataset

• Fan cells in lateral entorhinal cortex directly influence medial entorhinal cortex through synaptic connections in layer 1

  Vandrey, B. (Creator), Edinburgh DataShare, 12 Dec 2022

  DOI: 10.7488/ds/3787, https://www.biorxiv.org/content/10.1101/2022.08.25.505296v1

  Dataset

• Motyl AAL, et al. (2020). Pre-symptomatic developmental phenotypes in Spinal Muscular Atrophy

  MOTYL, A. (Creator), Gillingwater, T. (Creator) & Wishart, T. (Creator), Edinburgh DataShare, 3 Mar 2020

  DOI: 10.7488/ds/2776

  Dataset

• Data from: Automated single particle detection and tracking for large microscopy datasets

  Wilson, R. S. (Creator), Yang, L. (Creator), Dun, A. (Creator), Smyth, A. M. (Creator), Duncan, R. R. (Creator), Rickman, C. (Creator) & Lu, W. (Creator), Dryad, 22 Apr 2016

  DOI: 10.5061/dryad.6kg29, https://datadryad.org/stash/dataset/doi:10.5061/dryad.6kg29

  Dataset

• Non-fibrillar oligomeric amyloid-β within synapses: Data set from publication Pickett et al 2016 J Alz Dis

  Pickett, E. (Creator), Koffie, R. M. (Creator), Wegmann, S. (Creator), Henstridge, C. (Creator), Herrmann, A. (Creator), Colom-Cadena, M. (Creator), Lleo, A. (Creator), Kay, K. R. (Creator), Vaught, M. (Creator), Soberman, R. (Creator), Walsh, D. M. (Creator), Hyman, B. T. (Creator) & Spires-Jones, T. (Creator), Edinburgh DataShare, 3 Jun 2016

  DOI: 10.7488/ds/1415

  Dataset

• Whole blood mRNA expression profiling of host molecular networks in neonatal sepsis

  Smith, C. (Creator), Ghazal, P. (Creator), Dickinson, P. (Creator), Craigon, M. (Creator), Forster, T. (Hosting Institution) & Ross, A. (Creator), National Center for Biotechnology Information (Gene Expression Omnibus), 12 Aug 2014

  http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE25504

  Dataset

• An Investigation of Synaptic Dysfunction in Alzheimer’s Disease - Chapter 3 - Thresholding Macros

  Jackson, R. (Creator), Edinburgh DataShare, 5 Sept 2017

  DOI: 10.7488/ds/2133

  Dataset

• Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer’s disease - Data from 2017 Publication

  Spires-Jones, T. (Creator) & Pickett, E. (Creator), Edinburgh DataShare, 6 Feb 2017

  DOI: 10.7488/ds/1706, http://onlinelibrary.wiley.com/doi/10.1002/syn.21965/full

  Dataset

• Temporal coupling of axonal calcium responses and filopodia formation

  Ivanova, D. (Creator), Edinburgh DataShare, 20 Aug 2024

  DOI: 10.7488/ds/7794

  Dataset

• Proteomics datasets from Shorrock et al (UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy)

  Gillingwater, T. (Creator), Edinburgh DataShare, 8 Aug 2018

  DOI: 10.7488/ds/2405

  Dataset

• Neocortex saves energy by reducing coding precision during food scarcity

  Rochefort, N. (Creator), Padamsey, Z. (Creator) & Katsanevaki, D. (Creator), Edinburgh DataShare, 30 Nov 2021

  DOI: 10.7488/ds/3214, https://doi.org/10.1016/j.neuron.2021.10.024

  Dataset

• Figure 1 Gordon et al (2016) A fine balance of synaptophysin levels underlies efficient retrieval of synaptobrevin II to synaptic vesicles (PLOS ONE)

  Cousin, M. (Creator) & Smillie, K. (Creator), Edinburgh DataShare, 15 Jan 2016

  DOI: 10.7488/ds/1310

  Dataset

• Neuronal signature of spatial decision-making during navigation by freely moving rats by using calcium imaging

  Mitchell-Heggs, R. (Creator), Tse, D. (Creator), Schultz, S. R. (Creator), Morris, R. (Creator), Morris, R. (Creator) & Gobbo, F. (Creator), Edinburgh DataShare, 28 Oct 2022

  DOI: 10.7488/ds/3774

  Dataset

• Thesis Movies - 'Mechanisms of kidney vascularisation and the roles of macrophages in renal organogenesis'

  Munro, D. (Creator), Edinburgh DataShare, 13 Aug 2018

  DOI: 10.7488/ds/2413

  Dataset