• Postal address

    Crewe Road, Western General Hospital

    EH4 2XU Edinburgh

    United Kingdom

Organization profile

Organisation profile


Website: https://www.ed.ac.uk/institute-genetics-cancer


Director: Professor Margaret Frame 

Formerly the Institute of Genetics and Molecular Medicine (IGMM), the Institute of Genetics and Cancer (IGC) at The University of Edinburgh is an exciting development bringing together the MRC Human Genetics Unit, the Centre for Genomics and Experimental Medicine and the Cancer Research UK Edinburgh Centre.


This partnership constitutes one of the largest aggregates of human molecular genetics research capacity in the UK, and brings together over 500 research and support scientists in a single, scientific endeavour.


A principal aim of the Institute is to develop fully integrated, multi-disciplinary research programmes across the whole spectrum of basic, clinical and translational research. By providing access to a wide range of specialised facilities and services within a multi-disciplinary environment, IGMM supports and adds value to existing programmes of research.


The IGC's priorities are basic through to clinical research across the major themes of:

  • Brain Biology and Disease
  • Cancer
  • Common Disease Genetics
  • Paediatrics
  • All underpinned by strong basic science


Dive into the research topics where Institute of Genetics and Cancer is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.


Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
  • Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects

    Social Science Genetic Association Consortium, 9 May 2022, (E-pub ahead of print) In: Nature Genetics.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission

    Relph, K. A., Russell, C. D., Fairfield, C. J., Turtle, L., De Silva, T., Siggins, M. K., Drake, T. M., Thwaites, R. S., Abrams, S., Moore, S. C., Hardwick, H. E., Oosthuyzen, W., Harrison, E. M., Docherty, A. B., Openshaw, P. J. M., Baillie, J. K., Semple, M. G., Ho, A., Baillie, J. K., Semple, M. G. & 348 others, Openshaw, P. J. M., Carson, G., Alex, B., Bach, B., Barclay, W. S., Bogaert, D., Chand, M., Cooke, G. S., Docherty, A. B., Dunning, J., Filipe, A. D. S., Fletcher, T., Green, C. A., Harrison, E. M., Hiscox, J. A., Ho, A. Y. W., Horby, P. W., Ijaz, S., Khoo, S., Klenerman, P., Law, A., Lim, W. S., Mentzer, A. J., Merson, L., Meynert, A. M., Noursadeghi, M., Moore, S. C., Palmarini, M., Paxton, W. A., Pollakis, G., Price, N., Rambaut, A., Robertson, D. L., Russell, C. D., Sancho-shimizu, V., Scott, J. T., De Silva, T., Sigfrid, L., Solomon, T., Sriskandan, S., Stuart, D., Summers, C., Tedder, R. S., Thomson, E. C., Roger Thompson, A. A., Thwaites, R. S., Turtle, L. C. W., Gupta, R. K., Zambon, M., Hardwick, H., Donohue, C., Lyons, R., Griffiths, F., Oosthuyzen, W., Norman, L., Pius, R., Drake, T. M., Fairfield, C. J., Knight, S. R., Mclean, K. A., Murphy, D., Shaw, C. A., Dalton, J., Girvan, M., Saviciute, E., Roberts, S., Harrison, J., Marsh, L., Connor, M., Halpin, S., Jackson, C., Gamble, C., Leeming, G., Law, A., Wham, M., Clohisey, S., Hendry, R., Scott-brown, J., Greenhalf, W., Shaw, V., Mcdonald, S., Keating, S., Ahmed, K. A., Armstrong, J. A., Ashworth, M., Asiimwe, I. G., Bakshi, S., Barlow, S. L., Booth, L., Brennan, B., Bullock, K., Catterall, B. W. A., Clark, J. J., Clarke, E. A., Cole, S., Cooper, L., Cox, H., Davis, C., Dincarslan, O., Dunn, C., Dyer, P., Elliott, A., Evans, A., Finch, L., Fisher, L. W. S., Foster, T., Garcia-dorival, I., Greenhalf, W., Gunning, P., Hartley, C., Jensen, R. L., Jones, C. B., Jones, T. R., Khandaker, S., King, K., Kiy, R. T., Koukorava, C., Lake, A., Lant, S., Latawiec, D., Lavelle-langham, L., Lefteri, D., Lett, L., Livoti, L. A., Mancini, M., Mcdonald, S., Mcevoy, L., Mclauchlan, J., Metelmann, S., Miah, N. S., Middleton, J., Mitchell, J., Moore, S. C., Murphy, E. G., Penrice-randal, R., Pilgrim, J., Prince, T., Reynolds, W., Matthew Ridley, P., Sales, D., Shaw, V. E., Shears, R. K., Small, B., Subramaniam, K. S., Szemiel, A., Taggart, A., Tanianis-hughes, J., Thomas, J., Trochu, E., Van Tonder, L., Wilcock, E., Eunice Zhang, J., Flaherty, L., Maziere, N., Cass, E., Doce Carracedo, A., Carlucci, N., Holmes, A., Massey, H., Murphy, L., Wrobel, N., Mccafferty, S., Morrice, K., Maclean, A., Adeniji, K., Agranoff, D., Agwuh, K., Ail, D., Aldera, E. L., Alegria, A., Angus, B., Ashish, A., Atkinson, D., Bari, S., Barlow, G., Barnass, S., Barrett, N., Bassford, C., Basude, S., Baxter, D., Beadsworth, M., Bernatoniene, J., Berridge, J., Best, N., Bothma, P., Chadwick, D., Brittain-long, R., Bulteel, N., Burden, T., Burtenshaw, A., Caruth, V., Chadwick, D., Chambler, D., Chee, N., Child, J., Chukkambotla, S., Clark, T., Collini, P., Cosgrove, C., Cupitt, J., Cutino-moguel, M., Dark, P., Dawson, C., Dervisevic, S., Donnison, P., Douthwaite, S., Durand, I., Dushianthan, A., Dyer, T., Evans, C., Eziefula, C., Fegan, C., Finn, A., Fullerton, D., Garg, S., Garg, S., Garg, A., Gkrania-klotsas, E., Godden, J., Goldsmith, A., Graham, C., Hardy, E., Hartshorn, S., Harvey, D., Havalda, P., Hawcutt, D. B., Hobrok, M., Hodgson, L., Hormis, A., Jacobs, M., Jain, S., Jennings, P., Kaliappan, A., Kasipandian, V., Kegg, S., Kelsey, M., Kendall, J., Kerrison, C., Kerslake, I., Koch, O., Koduri, G., Koshy, G., Laha, S., Laird, S., Larkin, S., Leiner, T., Lillie, P., Limb, J., Linnett, V., Little, J., Lyttle, M., Macmahon, M., Macnaughton, E., Mankregod, R., Masson, H., Matovu, E., Mccullough, K., Mcewen, R., Meda, M., Mills, G., Minton, J., Mirfenderesky, M., Mohandas, K., Mok, Q., Moon, J., Moore, E., Morgan, P., Morris, C., Mortimore, K., Moses, S., Mpenge, M., Mulla, R., Murphy, M., Nagel, M., Nagarajan, T., Nelson, M., O’shea, M. K., Otahal, I., Ostermann, M., Pais, M., Panchatsharam, S., Papakonstantinou, D., Paraiso, H., Patel, B., Pattison, N., Pepperell, J., Peters, M., Phull, M., Pintus, S., Pooni, J. S., Post, F., Price, D., Prout, R., Rae, N., Reschreiter, H., Reynolds, T., Richardson, N., Roberts, M., Roberts, D., Rose, A., Rousseau, G., Ryan, B., Saluja, T., Shah, A., Shanmuga, P., Sharma, A., Shawcross, A., Sizer, J., Shankar-hari, M., Smith, R., Snelson, C., Spittle, N., Staines, N., Stambach, T., Stewart, R., Subudhi, P., Szakmany, T., Tatham, K., Thomas, J., Thompson, C., Thompson, R., Tridente, A., Tupper-carey, D., Twagira, M., Ustianowski, A., Vallotton, N., Vincent-smith, L., Visuvanathan, S., Vuylsteke, A., Waddy, S., Wake, R., Walden, A., Welters, I., Whitehouse, T., Whittaker, P., Whittington, A., Papineni, P., Wijesinghe, M., Williams, M., Wilson, L., Cole, S., Winchester, S., Wiselka, M., Wolverson, A., Wootton, D. G., Workman, A., Yates, B. & Young, P., 1 May 2022, In: Open forum infectious diseases. 9, 5

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Refining the domain architecture model of the replication origin firing factor Treslin/TICRR

    Ferreira, P., Sanchez-Pulido, L., Marko, A., Ponting, C. P. & Boos, D., 1 May 2022, In: Life Science Alliance. 5, 5

    Research output: Contribution to journalArticlepeer-review

    Open Access