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    Crewe Road, Western General Hospital

    EH4 2XU Edinburgh

    United Kingdom

Organisation profile

Organisation profile


Website: https://www.ed.ac.uk/institute-genetics-cancer


Director: Professor Margaret Frame 

Formerly the Institute of Genetics and Molecular Medicine (IGMM), the Institute of Genetics and Cancer (IGC) at The University of Edinburgh is an exciting development bringing together the MRC Human Genetics Unit, the Centre for Genomics and Experimental Medicine and the Cancer Research UK Edinburgh Centre.


This partnership constitutes one of the largest aggregates of human molecular genetics research capacity in the UK, and brings together over 500 research and support scientists in a single, scientific endeavour.


A principal aim of the Institute is to develop fully integrated, multi-disciplinary research programmes across the whole spectrum of basic, clinical and translational research. By providing access to a wide range of specialised facilities and services within a multi-disciplinary environment, IGMM supports and adds value to existing programmes of research.


The IGC's priorities are basic through to clinical research across the major themes of:

  • Brain Biology and Disease
  • Cancer
  • Common Disease Genetics
  • Paediatrics
  • All underpinned by strong basic science


Dive into the research topics where Institute of Genetics and Cancer is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
  • Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations

    Thomas, M., Su, Y-R., Rosenthal, E. A., Sakoda, L. C., Schmit, S. L., Timofeeva, M. N., Chen, Z., Fernandez-Rozadilla, C., Law, P. J., Murphy, N., Carreras-Torres, R., Diez-Obrero, V., Van duijnhoven, F. J. B., Jiang, S., Shin, A., Wolk, A., Phipps, A. I., Burnett-Hartman, A., Gsur, A., Chan, A. T., & 109 othersZauber, A. G., Wu, A. H., Lindblom, A., Um, C. Y., Tangen, C. M., Gignoux, C., Newton, C., Haiman, C. A., Qu, C., Bishop, D. T., Buchanan, D. D., Crosslin, D. R., Conti, D. V., Kim, D-H., Hauser, E., White, E., Siegel, E., Schumacher, F. R., Rennert, G., Giles, G. G., Hampel, H., Brenner, H., Oze, I., Oh, J. H., Lee, J. K., Schneider, J. L., Chang-Claude, J., Kim, J., Huyghe, J. R., Zheng, J., Hampe, J., Greenson, J., Hopper, J. L., Palmer, J. R., Visvanathan, K., Matsuo, K., Matsuda, K., Jung, K. J., Li, L., Le marchand, L., Vodickova, L., Bujanda, L., Gunter, M. J., Matejcic, M., Jenkins, M. A., Slattery, M. L., D’amato, M., Wang, M., Hoffmeister, M., Woods, M. O., Kim, M., Song, M., Iwasaki, M., Du, M., Udaltsova, N., Sawada, N., Vodicka, P., Campbell, P. T., Newcomb, P. A., Cai, Q., Pearlman, R., Pai, R. K., Schoen, R. E., Steinfelder, R. S., Haile, R. W., Vandenputtelaar, R., Prentice, R. L., Küry, S., Castellví-Bel, S., Tsugane, S., Berndt, S. I., Lee, S. C., Brezina, S., Weinstein, S. J., Chanock, S. J., Jee, S. H., Kweon, S-S., Vadaparampil, S., Harrison, T. A., Yamaji, T., Keku, T. O., Vymetalkova, V., Arndt, V., Jia, W-H., Shu, X-O., Lin, Y., Ahn, Y-O., Stadler, Z. K., Van guelpen, B., Ulrich, C. M., Platz, E. A., Potter, J. D., Li, C. I., Meester, R., Moreno, V., Figueiredo, J. C., Casey, G., Lansdorp vogelaar, I., Dunlop, M. G., Gruber, S. B., Hayes, R. B., Pharoah, P. D. P., Houlston, R. S., Jarvik, G. P., Tomlinson, I. P., Zheng, W., Corley, D. A., Peters, U. & Hsu, L., 2 Oct 2024, In: Nature Communications. 14, 1

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Open Access
  • Human trophectoderm becomes multi-layered by internalisation at the polar region

    Corujo Simon, E., Bates, L., Yanagida, A., Jones, K., Clark, S., von Meyenn, F., Reik, W. & Nichols, J., 17 Jun 2024, In: Developmental Cell.

    Research output: Contribution to journalArticlepeer-review

    Open Access