Institute of Genetics and Cancer

Research output

Research output per year 1972 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024

• 7754 Article
• 339 Meeting abstract
• 180 Review article
• 129 Literature review
• 745 More
  • 101 Abstract
  • 94 Chapter
  • 92 Letter
  • 91 Conference contribution
  • 83 Editorial
  • 67 Comment/debate
  • 40 Poster
  • 28 Book/Film/Article review
  • 27 Paper
  • 26 Chapter (peer-reviewed)
  • 18 Preprint
  • 14 Book
  • 9 Other chapter contribution
  • 9 Patent
  • 7 Other report
  • 6 Doctoral Thesis
  • 6 Working paper
  • 4 Other
  • 4 Special issue
  • 3 Conference article
  • 3 Short survey
  • 3 Web publication/site
  • 3 Other contribution
  • 2 Commissioned report
  • 1 Entry for encyclopedia/dictionary
  • 1 Digital or Visual Products
  • 1 Performance
  • 1 Protocols
  • 1 Master's Thesis

Research output per year

Research output per year

Search results

• 2024

  DNAm scores for serum GDF15 and NT-proBNP levels associate with a range of traits affecting the body and brain

  Gadd, D., Smith, H., Mullin, D., Chybowska, O., Hillary, R., Kimenai, D. M., Bernabeu, E., Cheng, Y., Fawns-Ritchie, C., Campbell, A., Page, D., Taylor, A., Corley, J., Valdés Hernández, M. C., Muñoz Maniega, S., Bastin, M. E., Wardlaw, J. M., Walker, R., Evans, K. L., McIntosh, A. M., & 8 othersHayward, C., Russ, T. C., Harris, S. E., Welsh, P., Sattar, N., Cox, S. R., McCartney, D. L. & Marioni, R. E., 10 Sept 2024, In: Nature. 16, 124.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Growth Differentiation Factor 100%
  • Growth Differentiation Factor 15 100%
  • Epigenetics 75%
  • Blood Level 12%
  • Natriuretic Peptide 12%

• Ethical considerations of use of hold-out sets in clinical prediction model management

  Chislett, L., Aslett, L. JM., Davies, A. R., Vallejos, C. A. & Liley, J., 10 Sept 2024, In: AI and Ethics.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Patient Coding 100%
  • Beneficence 100%
  • Sampling 100%
  • Autonomy 100%
  • Learning Model 100%

• Loss of DOCK2 potentiates Inflammatory Bowel Disease–associated colorectal cancer via immune dysfunction and IFNγ induction of IDO1 expression

  Churchhouse, A. M. D., Billard, C. V., Suzuki, T., Pohl, S. Ö. G., Doleschall, N. J., Donnelly, K., Nixon, C., Arends, M. J., Din, S., Kirkwood, K., Marques junior, J., Von kriegsheim, A., Coffelt, S. B. & Myant, K. B., 7 Sept 2024, (E-pub ahead of print) In: Oncogene.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Colorectal Cancer 100%
  • Inflammatory Bowel Disease 100%
  • Immune Disorder 100%
  • Carcinogenesis 100%
  • Neoplasm 83%

• Emergency and non-emergency routes to cancer diagnoses in 2020 and 2021: A Population-based study of 154,863 patients

  Purdie, C., Clark, G. R. C., Cameron, D. A., Petty, R., Mariappan, P., Graham, J., Burton, K. A. & Morrison, D. S., 1 Dec 2024, In: Journal of Cancer Policy. 42, p. 100502

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Inverse correlation between TP53 gene status and PD-L1 protein levels in a melanoma cell model depends on an IRF1/SOX10 regulatory axis

  Martinkova, L., Zatloukalova, P., Kucerikova, M., Friedlova, N., Tylichova, Z., Zavadil-Kokas, F., Hupp, T. R., Coates, P. J. & Vojtesek, B., 5 Sept 2024, (E-pub ahead of print) In: Cellular & Molecular Biology Letters. 29, 1

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • IRF1 100%
  • SOX10 100%
  • Interferon Regulatory Factor 1 100%
  • Melanoma Cell 100%
  • Natural Killer Cell 12%

• Lentiviral Gene Therapy for Cystic Fibrosis: A Promising Approach and First-In-Human Trial

  Davies, J. C., Polineni, D., Boyd, A. C., Donaldson, S., Gill, D. R., Griesenbach, U., Hyde, S. C., Jain, R., McLachlan, G., Mall, M. A. & Alton, E. W., 5 Sept 2024, (E-pub ahead of print) In: American Journal of Respiratory and Critical Care Medicine.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cystic Fibrosis Transmembrane Conductance Regulator 100%
  • Antisense Therapy 28%
  • Viral Vector 28%
  • Sendai Virus 14%
  • Envelope Protein 14%

• Genome-Wide Interaction Analyses of Serum Calcium on Ventricular Repolarization Time in 125 393 Participants

  LifeLines Cohort Study, 3 Sept 2024, In: Journal of the American Heart Association. 13, 17, 16 p., e034760.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Calcium Blood Level 100%
  • Repolarization 100%
  • Electrocardiogram 33%
  • Cardiac Dysrhythmia 33%

• Tuning singlet oxygen generation with caged organic photosensitizers

  Nestoros, E., De Moliner, F., Nadal-Bufi, F., Seah, D., Ortega Liebana, M. C., Cheng, Z., Benson, S., Adam, C., Maierhofer, L., Kozoriz, K., Lee, J-S., Unciti-Broceta, A. & Vendrell, M., 3 Sept 2024, In: Nature Communications.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Carbamates 100%

• Cancer drug-tolerant Persister cells: from biological questions to clinical opportunities

  Russo, M., Chen, M., Mariella, E., Peng, H., Rehman, S. K., Sancho, E., Sogari, A., Toh, T. S., Balaban, N. Q., Batlle, E., Bernards, R., Garnett, M. J., Hangauer, M., Leucci, E., Marine, J-C., O’Brien, C. A., Oren, Y., Patton, E. E., Robert, C., Rosenberg, S. M., & 2 othersShen, S. & Bardelli, A., 2 Sept 2024, In: Nature Reviews Cancer.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Malignant Neoplasm 100%
  • Drug Resistance 100%
  • Tumor Microenvironment 33%
  • Neoplasm 33%
  • Antibiotic Agent 33%

• Structural epitope profiling identifies antibodies associated with critical COVID-19 and long COVID

  Kearns, P., Dixon, C., Badonyi, M., Lee, K., Czapiewski, R., Fleming, O., Nadukkandy, P., Gerasimavicius, L., Sahputra, R., Marsh, J. A. & Gilbert, N., 2 Sept 2024, In: eLIFE.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Postcovid Syndrome 100%
  • Monospecific Antibody 100%
  • COVID-19 100%
  • Epitope 100%
  • Severe Acute Respiratory Syndrome Coronavirus 2 28%

• Higher ultraviolet light exposure is associated with lower mortality: An analysis of data from the UK biobank cohort study

  Stevenson, A. C., Clemens, T., Pairo-Castineira, E., Webb, D. J., Weller, R. B. & Dibben, C., Sept 2024, In: Health & Place. 89, p. 1-8 8 p., 103328.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ultraviolet Light Exposure 100%
  • Cardiovascular System Cancer 50%

• The utility of whole-genome sequencing to identify likely transmission pairs for pathogens with slow and variable evolution

  Wood, A. J., Benton, C. H., Delahay, R. J., Marion, G., Palkopoulou, E., Pooley, C. M., Smith, G. C. & Kao, R. R., Sept 2024, In: Epidemics. 48, p. 1-10 10 p., 100787.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pathogen 100%
  • Meles 33%
  • RNA Virus 33%

• Structural insight into the function of human peptidyl arginine deiminase 6

  Williams, J. P. C., Mouilleron, S., Hernandez Trapero, R., Bertran, M. T., Marsh, J. A. & Walport, L. J., 31 Aug 2024, In: Computational and Structural Biotechnology Journal. 23, p. 3258-3269

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Arginine Deiminase 100%
  • Active Site 100%
  • Histidine 50%
  • Catalysis 50%
  • Aspartic Acid 50%

• Estimating cancer risk in carriers of Lynch syndrome variants in UK Biobank

  Fummey, E., Navarro, P., Plazzer, J-P., Frayling, I. M., Knott, S. & Tenesa, A., 29 Aug 2024, In: Journal of Medical Genetics. 61, 9, p. 861-869 9 p., e109791.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • MSH6 100%
  • Cancer Incidence 100%

• Hereditary C1q deficiency is associated with type 1 interferon-pathway activation and a high risk of central nervous system inflammation

  Triaille, C., Mohan Rao, N., Rice, G. I., Seabra, L., Sutherland, F., Bondet, V., Duffy, D., Gennery, A. R., Fournier, B., Bader-Meunier, B., Troedson, C., Cleary, G., Buso, H., Dalby-Payne, J., Ranade, P., Jansen, K., De Somer, L., Frémond, M-L., Pimpale Chavan, P., Wong, M., & 5 othersDale, R. C., Wouters, C., Quartier, P., Khubchandani, R. & Crow, Y. J., 28 Aug 2024, In: Journal of Clinical Immunology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Complement Component C1q 100%
  • Interferon 100%
  • Alpha Interferon 42%
  • Interferon Alfa 42%
  • Systemic Lupus Erythematosus 28%

• InstanSeg: An embedding-based instance segmentation algorithm optimized for accurate, efficient and portable cell segmentation

  Goldsborough, T., Philps, B., O'Callaghan, A., Inglis, F., Leplat, L., Filby, A., Bilen, H. & Bankhead, P., 28 Aug 2024, ArXiv.

  Research output: Working paper › Preprint

  File

  • Instance Segmentation 100%
  • segmentation algorithm 100%
  • Cell Segmentation 100%
  • Open Source 50%
  • Processing Time 50%

• Systematic discovery of gene-environment interactions underlying the human plasma proteome in UK Biobank

  Hillary, R., Gadd, D., Kuncheva, Z., Mangelis, T., Lin, T., Ferber, K., McLaughlin, H., Runz, H., Biogen Biobank Team, Marioni, R. E., Foley, C. N. & Sun, B. B., 26 Aug 2024, (E-pub ahead of print) In: Nature Communications.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Pharmacological and pre-clinical safety profile of rSIV.F/HN, a hybrid lentiviral vector for cystic fibrosis gene therapy

  Moiseenko, A., Sinadinos, A., Sergijenko, A., Pineault, K., Saleh, A., Nekola, K., Strang, N., Eleftheraki, A., Boyd, A. C., Davies, J. C., Gill, D. R., Hyde, S. C., McLachlan, G., Rath, T., Rothe, M., Schambach, A., Hobbie, S., Schuler, M., Maier, U., Thomas, M. J., & 5 othersMennerich, D., Schmidt, M., Griesenbach, U., Alton, E. W. F. W. & Kreuz, S., 22 Aug 2024, (E-pub ahead of print) In: European Respiratory Journal. 64, 2

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cystic Fibrosis Transmembrane Conductance Regulator 100%
  • Regulator Protein 16%
  • Ivacaftor 8%

• Proteome-scale prediction of molecular mechanisms underlying dominant genetic diseases

  Badonyi, M. & Marsh, J. A., 22 Aug 2024, In: PLoS ONE.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Proteome 100%
  • Genetic Disorder 100%
  • Missense Mutation 50%
  • Gene Therapy 50%
  • Small Molecule 50%

• Fluidification of entangled polymers by loop extrusion

  Conforto, F., Gutierrez Fosado, Y. & Michieletto, D., 12 Aug 2024, In: Physical Review Research. 6, 3, p. 1-10 10 p., 033160.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • DNA 100%
  • Viscoelasticity 100%
  • Nucleoplasm 50%
  • Main Process 33%

• Loops are Geometric Catalysts for DNA Integration

  Battaglia, C. & Michieletto, D., 12 Aug 2024, In: Nucleic Acids Research. 52, 14, p. 8184-8192 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • DNA Integration 100%
  • Gene Insertion 66%

• Cyclin F - EXO1 axis controls cell cycle dependent execution of double strand break repair

  Yang, H., Fouad, S., Smith, P., Young Bae, E., Ji, Y., Lan, X., Van Ess, A., Buffa, F. M., Fischer, R., Vendrell, I., Kessler, B. M. & D'Angiolella, V., 9 Aug 2024, (E-pub ahead of print) In: Science Advances.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Proliferating Cell Nuclear Antigen 100%
  • Cell Cycle Regulation 100%
  • Cyclin 100%
  • CRISPR 33%
  • Cell Survival 25%

• Not all are the same – the power of registries in defining genotype-phenotype relationships in primary ciliary dyskinesia

  Horani, A. & Mill, P., 8 Aug 2024, In: European Respiratory Journal. 64, 2, 2401026.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

  File

  • Primary Ciliary Dyskinesia 100%
  • Rare Disease 100%

• Whole genome sequencing enhances molecular diagnosis of primary ciliary dyskinesia

  Scottish Genomes Partnership, Santoyo-Lopez, J., Murray, J. E., Macleod, K., Urquhart, D. S., Unger, S. A., Aitman, T. J. & Mill, P., 8 Aug 2024, (E-pub ahead of print) In: Pediatric Pulmonology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Hemispheric Dominance 100%

• Identifying and reducing risks of neurological complications associated with vaccination

  Handunnetthi, L., Ramasamy, M. N., Turtle, L. & Hunt, D. P. J., 7 Aug 2024, (E-pub ahead of print) In: Nature Reviews Neurology.

  Research output: Contribution to journal › Review article › peer-review

  • Vaccination Policy 100%
  • Live Vaccine 100%
  • Attenuated Vaccine 100%
  • COVID-19 40%
  • Vaccine Efficacy 40%

• Postoperative radiotherapy in women with early operable breast cancer (Scottish Breast Conservation Trial): 30-year update of a randomised, controlled, phase 3 trial

  Williams, L. J., Kunkler, I., Taylor, K., Dunlop, J., Piper, T., Caldwell, J., Jack, W., Loane, J., Elder, K., Bartlett, J., Dixon, M. & Cameron, D. A., 7 Aug 2024, (E-pub ahead of print) In: The Lancet Oncology. 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Methotrexate 100%
  • Tamoxifen 100%

• DNA-binding factor footprints and enhancer RNAs identify functional non-coding genetic variants

  Biddie, S., Weykopf, G., Hird, E. F., Friman, E. & Bickmore, W. A., 6 Aug 2024, In: Genome Biology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Enhancer RNAs 100%
  • Deoxyribonuclease 66%
  • Leukocyte Count 33%

• Melanocyte lineage dynamics in development, growth and disease

  Brombin, A. & Patton, E. E., 2 Aug 2024, In: Development.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Growth, Development and Aging 100%
  • Melanocyte 100%
  • Differentiation 22%
  • Skin 22%
  • Nodular Melanoma 22%

• Tracking ovine pulmonary adenocarcinoma development using an experimental Jaagsiekte sheep retrovirus infection model

  Cousens, C., Meehan, J., Collie, D., Wright, S., Chang, Z., Todd, H., Moore, J., Grant, L., Daniel, C., Tennant, P., Ritchie, A., Nixon, J., Proudfoot, C., Guido, S., Brown, H., Gray, C., MacGillivray, T., Clutton, E., Greenhalgh, S., Gregson, R., & 5 othersJ Griffiths, D., Spivey, J., Storer, N., Eckert, C. & Gray, M., 2 Aug 2024, In: Genes. 15, 8, p. 1-21 21 p., 1019.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Jaagsiekte 100%
  • Jaagsiekte Sheep Retrovirus 100%
  • Sheep 27%

• Systematic investigation of genetically determined plasma and urinary metabolites to discover potential interventional targets for colorectal cancer

  Sun, J., Zhao, J., Zhou, S., Li, X., Li, T., Wang, L., Yuan, S., Chen, D., Law, P. J., Larsson, S. C., Farrington, S. M., Houlston, R. S., Dunlop, M. G., Theodoratou, E. & Li, X., 1 Aug 2024, In: Journal of the National Cancer Institute (JNCI). 116, 8, p. 1303-1312 10 p., djae089.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Actinobacteria 100%
  • Lactose 85%
  • Sphingomyelin 85%

• Unconventional Catalysis in the Countryside

  Rebrov, E. V. & Unciti-Broceta, A., 1 Aug 2024, In: Catalysis today.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

  File

• Molecules targeting a novel homotrimer cavity of Spike protein attenuate replication of SARS-CoV-2

  Daniels, A., Padariya, M., Fletcher, S., Ball, K., Singh, A., Carragher, N., Hupp, T., Tait-Burkard, C. & Kalathiya, U., Aug 2024, In: Antiviral Research. 228, p. 1-14 14 p., 105949.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Spike 100%
  • Virion 20%
  • Glycoprotein 20%

• Inheritance of STING mosaicism in two half-siblings

  SAVI study group & Crow, Y. J., 30 Jul 2024, In: Journal of Clinical Immunology.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File

• Long-term outcomes and predictors of vedolizumab persistence in ulcerative colitis

  Gros, B., Ross, H., Nwabueze, M., Constantine-Cooke, N., Derikx, L. A. A. P., Lyons, M., O'Hare, C., Noble, C., Arnott, I. D., Jones, G-R., Lees, C. W. & Plevris, N., 30 Jul 2024, In: Therapeutic Advances in Gastroenterology. 17, 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Vedolizumab 100%
  • Ulcerative Colitis 100%
  • Inflammatory Bowel Disease 30%
  • Biological Product 10%
  • Cohort Study 10%

• The SRC family kinase inhibitor NXP900 demonstrates potent anti-tumor activity in squamous cell carcinomas

  Dash, S., Hanson, S., King, B., Nyswaner, K., Foss, K., Tesi, N., Harvey, M. J. B., Navarro-Marchal, S. A., Woods, A., Poradosu, E., Unciti-Broceta, A., Carragher, N. O. & Brognard, J., 30 Jul 2024, (E-pub ahead of print) In: Journal of Biological Chemistry. p. 107615

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Bosutinib 100%
  • Dasatinib 100%

• Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non‐demented individuals

  Lorenzini, L., Collij, L. E., Tesi, N., Vilor‐tejedor, N., Ingala, S., Blennow, K., Foley, C., Frisoni, G. B., Haller, S., Holstege, H., Van der van der lee, S., Martinez‐lage, P., Marioni, R. E., Mccartney, D. L., O’ brien, J., Oliveira, T. G., Payoux, P., Reinders, M., Ritchie, C., Scheltens, P., & 13 othersSchwarz, A. J., Sudre, C. H., Waldman, A. D., Wolz, R., Chatelat, G., Ewers, M., Wink, A. M., Mutsaerts, H. J. M. M., Gispert, J. D., Visser, P. J., Tijms, B. M., Altmann, A. & Barkhof, F., 29 Jul 2024, (E-pub ahead of print) In: Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• A common mechanism for recruiting the Rrm3 and RTEL1 accessory helicases to the eukaryotic replisome

  Olson, O., Pelliciari, S., Heron, E. D. & Deegan, T. D., 22 Jul 2024, In: The EMBO journal.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Replisome 100%
  • DNA Polymerase 14%

• Estimating risk of consequences following hypoglycaemia exposure using the Hypo-RESOLVE cohort: a secondary analysis of pooled data from insulin clinical trials

  Mellor, J., Kuznetsov, D., Heller, S., Gall, M-A., Rosilio, M., Amiel, S. A., Ibberson, M., McGurnaghan, S., Blackbourn, L., Berthon, W., Salem, A., Qu, Y., McCrimmon, R. J., de Galan, B. E., Pedersen-Bjergaard, U., Leaviss, J., McKeigue, P. M. & Colhoun, H. M., 22 Jul 2024, (E-pub ahead of print) In: Diabetologia. 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Hypoglycemia 100%
  • Hemoglobin A1c 11%
  • Insulin Dependent Diabetes Mellitus 11%
  • Neuropathy 11%
  • Adverse Outcome 5%

• The effects of ciclosporin and methotrexate on kidney function in the treatment of severe atopic dermatitis in children – results from the TREAT trial

  Bruce, G., Rosala-Hallas, A., Jones, A. P., Turner, C., Dalton, N., Hilger, E., Baron, S., Beattie, P., Browne, F., Brown, S. J., Gach, J. E., Hearn, R., Esdaile, B., Cork, M. J., Howard, E., Greenblatt, D., August, S., Lovgren, M-L., Ashoor, F., Williamson, P., & 11 othersMcpherson, T., O'kane, D., Ravenscroft, J., Shaw, L., Spowart, C., Thomas, B. R., Sach, T., Wan, M., Irvine, A. D., Sinha, M. D. & Flohr, C., 15 Jul 2024, (E-pub ahead of print) In: British journal of dermatology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• A phenome-wide association and factorial Mendelian randomization study on the repurposing of uric acid-lowering drugs for cardiovascular outcomes

  Wang, L., Mesa Eguiagaray, I., Campbell, H., Wilson, J. F., Vitart, V., Li, X. & Theodoratou, E., 11 Jul 2024, (E-pub ahead of print) In: European Journal of Epidemiology. 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Peripheral Vascular Disease 100%
  • Coronary Artery Atherosclerosis 100%
  • Gout 50%
  • Xanthine Oxidase Inhibitor 50%
  • Congestive Heart Failure 50%

• Blood protein assessment of leading incident diseases and mortality in UK Biobank

  Biogen Bank Team, Gadd, D., Hillary, R. F., Kuncheva, Z. K., Cheng, Y., Dissanayake, M., Admanit, R., Gagnon, J., Lin, T., Ferber, K., Runz, H., Foley, C. N., Marioni, R. E. & Sun, B. B., 10 Jul 2024, (E-pub ahead of print) In: Nature Aging.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • UK Biobank 100%
  • Blood 100%
  • Protein 100%
  • Maturity Onset Diabetes of the Young 40%
  • Proteome 40%

• Antidepressant and antipsychotic prescribing in patients with type 2 diabetes in Scotland: a time-trend analysis from 2004-2021

  on behalf of The Scottish Diabetes Research Network Epidemiology Group, Greene, C., Blackbourn, L., McGurnaghan, S., Mercer, S. W., Smith, D., Wild, S. H., Honghan, W. & Jackson, C. A., 9 Jul 2024, In: British Journal of Clinical Pharmacology. 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Antidepressant 100%
  • Prevalence 83%
  • Typical Antipsychotic 66%

• Involvement of Kindlin-1 in cutaneous squamous cell carcinoma

  Carrasco, G., Stavrou, I., Treanor-Taylor, M., Beetham, H., Lee, M., Masalmeh, R., Carreras-Soldevila, A., Hardman, D., Bernabeu, M. O., von Kriegsheim, A., Inman, G. J., Byron, A. & Brunton, V. G., 9 Jul 2024, (E-pub ahead of print) In: Oncogenesis. 13, 1

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Squamous Cell 100%
  • Tumor Spheroid 50%
  • Metalloendopeptidase 50%
  • Loss of Function Mutation 33%
  • Actinic Keratosis 33%

• Whole exome sequencing reveals diverse genomic relatedness between paired concurrent endometrial and ovarian carcinomas

  Southworth, E., Thomson, J., Croy, I., Churchman, M., Arends, M. J., Hollis, R., Gourley, C. & Herrington, C. S., 6 Jul 2024, In: European Journal of Cancer.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Allele 100%
  • Exon 100%
  • ARID1A 100%

• Human life within a narrow range: the lethal ups and downs of type I interferons

  Crow, Y. J. & Casanova, J-L., 5 Jul 2024, In: Science Immunology.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Interferon Type I 100%
  • Viral Disease 28%
  • Inflammatory Disorder 14%
  • Viral Diseases Treatment 14%

• ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma

  Lu, Y., Travnickova, J., Badonyi, M., Rambow, F., Coates, A., Khan, Z., Marques Junior, J., Murphy, L. C., Garcia-Martinez, P., Marais, R., Louphrasitthiphol, P., Chan, A. H. Y., Schofield, C. J., von Kriegsheim, A., Marsh, J. A., Pavet, V., Sansom, O. J., Illingworth, R. S. & Patton, E. E., 3 Jul 2024, In: Cell Reports. 43, 7, 114406.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Melanoma 100%
  • Aldehyde Dehydrogenase 100%
  • Histone H3 50%
  • Nifuroxazide 25%
  • Acetate Coenzyme A Ligase 25%

• FANCD2 expression affects platinum response and further characteristics of high grade serous ovarian cancer in cells with different genetic backgrounds

  Taylor, S., Hollis, R., Gourley, C., Herrington, C. S., Langdon, S. P. & Arends, M. J., 2 Jul 2024, In: Experimental and Molecular Pathology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Fanconi Anemia Group D2 Protein 100%
  • Cross-Link 49%

• An overview of the molecular pathology of ovarian carcinomas

  Bell, S., Mckeeve, C., Roxburgh, P. & Herrington, C. S., 1 Jul 2024, In: Diagnostic Histopathology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Molecular Pathology 100%
  • Krukenberg Tumor 100%
  • Ovarian Cancer 80%
  • Serous Carcinoma 40%
  • Morphology 20%

• Emollient application from birth to prevent eczema in high-risk children: the BEEP RCT

  Bradshaw, L. E., Wyatt, L. A., Brown, S. J., Haines, R. H., Montgomery, A. A., Perkin, M. R., Sach, T. H., Lawton, S., Flohr, C., Ridd, M. J., Chalmers, J. R., Brooks, J., Swinden, R., Mitchell, E. J., Tarr, S., Jay, N., Thomas, K. S., Allen, H., Cork, M. J., Kelleher, M. M., & 5 othersSimpson, E. L., Lartey, S. T., Davies-Jones, S., Boyle, R. J. & Williams, H. C., 1 Jul 2024, In: Health Technology Assessment. 28, 29, p. 1-116

  Research output: Contribution to journal › Article › peer-review

  • Emollient Agent 100%
  • Food Allergy 28%
  • Skin Infection 21%
  • Allergic Rhinitis 14%
  • Atopy 14%

• Insights into Digit Evolution from a Fate Map Study of the Forearm Using Chameleon, a New Transgenic Chicken Line: Fate Mapping the Chicken Ulna

  Oh, J., Freem, L., Saunders, D., McTeir, L., Gilhooley, H., Jackson, M., Glover, J., Smith, J., Schoenebeck, J., Lettice, L. A., Sang, H. & Davey, M., 1 Jul 2024, In: Development. 151, 13, p. 1-14 14 p., dev202340.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Fate Mapping 100%