Small Vessel Disease Research

Projects

Projects per year 2006 2010 2011 2012 2013 2015 2016 2017 2018 2019 2025

• 9 Active
• 131 Finished

Projects per year

Search results

• Finished

  SVDs-at-target: Small vessel diseases in a mechanistic perspective: Targets for Intervention Affected pathways and mechanistic exploitation for prevention of stroke and dementia

  Wardlaw, J.

  EU government bodies

  1/01/16 → 31/12/21

  Project: Research

  • White Matter 100%
  • Stroke 86%
  • Cerebral Small Vessel Diseases 71%
  • Brain 45%
  • Lacunar Stroke 44%

• DPUK-IMAGING INFORMATICS

  Gourley, C., Job, D. & Wardlaw, J.

  Other

  1/01/16 → 8/07/17

  Project: Research

• Accuracy, pattern and possible underlying factors of brain microbleeds progression on older adults with absence or mild presence of vascular pathology

  Valdes Hernandez, M.

  1/01/16 → 31/03/16

  Project: University Awarded Project Funding

  • Pathology 100%
  • Blood Vessels 93%
  • Magnetic Resonance 82%
  • Brain 77%
  • Cholesterol 72%

• Small vessel disease pathophysiology: human postmortem brain tissue study with clinical radiological pathological correlation - Fellowship for Catherine Humphreys

  Wardlaw, J. & Smith, C.

  UK-based charities

  1/12/15 → 31/12/19

  Project: Research

• ECAT (203699) Multi-modality imaging assessment of cerebral small vessel disease biomarkers after stroke due to spontaneous intracerebral haemorrhage

  Wardlaw, J. & Salman, R.

  UK-based charities

  1/12/15 → 30/11/18

  Project: Research

  • Cerebral Amyloid Angiopathy 100%
  • Cerebral Hemorrhage 76%
  • systematic review 45%
  • meta-analysis 40%
  • Routine Diagnostic Tests 38%

• Preventing cognitive decline and dementia from cerebral microvascular disease

  Wardlaw, J.

  UK-based charities

  1/10/15 → 31/07/18

  Project: Research

  • isosorbide-5-mononitrate 100%
  • Cerebral Small Vessel Diseases 94%
  • Cilostazol 94%
  • Lacunar Stroke 85%
  • Dementia 53%

• Row Fogo Charitable Trust Funds

  Wardlaw, J.

  UK-based charities

  1/10/15 → 30/09/18

  Project: Research

  • White Matter 100%
  • Cerebral Small Vessel Diseases 80%
  • Stroke 47%
  • Brain 42%
  • Aptitude 38%

• Equipment Grant - MR Scanner

  Wardlaw, J.

  UK-based charities

  1/08/15 → 31/07/20

  Project: Research

• Senior Clinical Lectureship: A platform for patient focused trials to prevent cerebral small vessel disease

  Doubal, F.

  UK-based charities

  1/06/15 → 31/05/21

  Project: Research

  • isosorbide-5-mononitrate 100%
  • Cerebral Small Vessel Diseases 94%
  • Cilostazol 94%
  • Lacunar Stroke 93%
  • Stroke 74%

• Right-2 Imaging Resources - Rapid Intervention With Glyceryl Trinitrate In Hypertensive Stroke Trial-2 (Right-2)

  Wardlaw, J.

  Other

  1/05/15 → 31/10/18

  Project: Research

  • isosorbide-5-mononitrate 100%
  • Cilostazol 94%
  • Lacunar Stroke 85%
  • Ambulances 77%
  • Nitroglycerin 73%

• Brain imaging and cognitive ageing in the Lothian Birth Cohort 1936: III

  Wardlaw, J., Bastin, M. & Deary, I.

  MRC

  1/05/15 → 30/04/19

  Project: Research

  • White Matter 100%
  • Parturition 93%
  • Brain 88%
  • Aptitude 63%
  • DNA Methylation 51%

• TEST Multi-modal retinal biomarkers for vascular dementia: developing enabling image analysis tools

  Wardlaw, J.

  Other

  30/04/15 → 28/08/18

  Project: Research

  • Microvessels 100%
  • Independent Living 90%
  • dementia 87%
  • Dementia 85%
  • Retinal Vessels 65%

• Quantification of vascular disease burden to stratify dementia for diagnosis and care management

  Valdes Hernandez, M. & Wardlaw, J.

  1/04/15 → 31/03/17

  Project: Research Collaboration with external organisation

  • Pathology 100%
  • White Matter 87%
  • Brain 61%
  • Magnetic resonance imaging 52%
  • Magnetic Resonance Spectroscopy 49%

• Quantification of vascular disease burden to stratify dementia for diagnosis and care management

  Wardlaw, J.

  UK central government bodies/local authorities, health and hospital authorities

  1/04/15 → 30/06/17

  Project: Research

  • Leukoaraiosis 100%
  • Metadata 64%
  • Brain 64%
  • Brain Injuries 63%
  • Stroke 55%

• Pragmatic Ischaemic Stroke Thrombectomy Evaluation

  Wardlaw, J.

  Other

  1/04/15 → 29/02/16

  Project: Research

• UKDP: Integrated DEmentiA research environment (IDEA)

  van Beek, E., Chandran, S., Deary, I., Ffrench-Constant, C. & Wardlaw, J.

  MRC

  1/04/15 → 30/06/16

  Project: Research

  • dementia 100%
  • Reproducibility of Results 88%
  • Dementia 83%
  • incident 81%
  • Psychometrics 69%

• Progression pattern of brain mineral deposition as a differential indicator of cognitive decline

  Valdes Hernandez, M. & Clayson, L.

  1/01/15 → 31/03/15

  Project: University Awarded Project Funding

  • Magnetic Resonance 100%
  • Minerals 93%
  • Cholesterol 86%
  • Basal Ganglia 78%
  • Cognitive Dysfunction 63%

• EPAD: European Prevention Of Alzheimer's Dementia Consortium (Janssen)

  Wardlaw, J.

  EU government bodies

  1/01/15 → 31/10/20

  Project: Research

• Magnetic Resonance Imaging of Lifecourse Influences on Brain Health and Disease (Biomedical Resource/Multi-User Equipment/Technology Development Grant)

  Wardlaw, J., Boardman, J., Marshall, I., McIntosh, A. & Salman, R.

  UK-based charities

  1/01/15 → 31/12/19

  Project: Research

• Textural Characterisation on Regions of Interest: A useful Tool for the Study of Small Vessel Disease

  Valdes Hernandez, M. & Viksne, L.

  1/01/15 → 31/03/15

  Project: University Awarded Project Funding

  File

  • honor 100%
  • Stroke 32%
  • Entropy 28%
  • Brain 23%
  • White Matter 21%

• Visualising the brain iPad App

  Wardlaw, J.

  UK-based charities

  1/12/14 → 31/03/15

  Project: Research

• Brain Imaging in Normal Subjects (BraINS): a searchable living brain image bank to improve brain scan reporting and diagnosis of pathological ageing

  Wardlaw, J. & Shenkin, S.

  UK-based charities

  25/11/14 → 24/11/15

  Project: Research

  • Atlases 100%
  • Brain 91%
  • Neuroimaging 84%
  • Magnetic Resonance Spectroscopy 78%
  • Pathology 58%

• Row Fogo Charitable Trust Funds

  Wardlaw, J.

  UK-based charities

  10/11/14 → 9/11/17

  Project: Research

  • Stroke 100%
  • White Matter 69%
  • Lacunar Stroke 53%
  • Brain 51%
  • Blood-Brain Barrier 35%

• Pilot testing ot a magentic resonance

  Wardlaw, J.

  UK-based charities

  1/06/14 → 31/08/14

  Project: Research

• Non-invasive measurement of cerebrovascular reactivity and compliance in cerebral small vessel disease: feasibility and estimation of sample size for translation research and clinical trials

  Wardlaw, J.

  UK central government bodies/local authorities, health and hospital authorities

  1/02/14 → 31/07/16

  Project: Research

  • Cerebral Small Vessel Diseases 100%
  • Systematic Reviews 25%
  • Magnetic Resonance Imaging 22%
  • White Matter 21%
  • Volunteers 11%

• Predictors of long term cognitive impairment, dementia and disability after lacunar stroke

  Wardlaw, J.

  UK-based charities

  1/01/14 → 30/06/16

  Project: Research

  • Social Class 100%
  • Meta-Analysis 87%
  • Cerebral Small Vessel Diseases 85%
  • Stroke 80%
  • Intelligence 61%

• Analysis of morphological structural changes in brains of patients that had a symptomatic lacunar stroke

  Valdes Hernandez, M. & Wardlaw, J.

  1/01/14 → 31/03/14

  Project: University Awarded Project Funding

  • Hemisphere 100%
  • Hemispheric Differences 81%
  • Infarction 77%
  • Contamination 55%
  • Medical Sciences 49%

• RA2665 Centre for Cognitive Ageing and Cognitive Epidemiology Phase 2.

  Wardlaw, J.

  1/09/13 → 31/08/19

  Project: Research

  • DNA Methylation 100%
  • Aptitude 67%
  • Parturition 67%
  • Brain 59%
  • Epigenomics 57%

• Centre for Cognitive Ageing & Cognitive Epidemiology - Studentships

  Deary, I., Maclullich, A., Porteous, D., Seckl, J. & Wardlaw, J.

  MRC

  1/09/13 → 31/08/19

  Project: Research

  • Systematic Reviews 100%
  • Cognitive Dysfunction 95%
  • cognitive ability 86%
  • Aptitude 79%
  • Cerebral Small Vessel Diseases 63%

• RA2664 Centre for Cognitive Ageing and Cognitive Epidemiology Phase 2 KNOWLEDGE EXCHANGE BUDGET

  Deary, I., Maclullich, A., Porteous, D., Seckl, J. & Wardlaw, J.

  1/09/13 → 31/08/19

  Project: Research

  • Single Nucleotide Polymorphism 100%
  • Genome-Wide Association Study 92%
  • cognitive ability 61%
  • Aptitude 59%
  • Cerebral Small Vessel Diseases 56%

• Centre for Cognitive Ageing and Cognitive Epidemiology Phase 2. Main Budget.

  Deary, I., Anand, A., Gale, C., Holmes, M., Logie, P., Luciano, M., Maclullich, A., Porteous, D., Seckl, J., Starr, J. & Wardlaw, J.

  UK-based charities, MRC, Other

  1/09/13 → 28/02/19

  Project: Research

  • Intelligence 100%
  • Aptitude 96%
  • brain 79%
  • Biobank 77%
  • Parturition 77%

• RA2661 Centre for Cognitive Ageing and Cognitive Epidemiology Phase 2. Main Budget.

  Deary, I., Gale, C., Holmes, M., Logie, P., Maclullich, A., Porteous, D., Seckl, J., Starr, J., Wardlaw, J. & Okely, J.

  1/09/13 → 31/08/19

  Project: Research

  • Intelligence 100%
  • Aptitude 88%
  • Genome-Wide Association Study 83%
  • Cognition 77%
  • Parturition 69%

• Centre for Cognitive Ageing and Cognitive Epidemiology Phase 2 PILOTS BUDGET (Genotyping and Brain Imaging).

  Deary, I., Maclullich, A., Porteous, D., Seckl, J. & Wardlaw, J.

  MRC

  1/09/13 → 31/08/19

  Project: Research

  • Cerebral Small Vessel Diseases 100%
  • Single Nucleotide Polymorphism 88%
  • Genome-Wide Association Study 81%
  • cognitive ability 54%
  • Aptitude 53%

• Imaging cerebrovascular alterations and their modulation in experimental models: a translational approach

  Horsburgh, K., Marshall, I. & Wardlaw, J.

  UK-based charities

  1/09/13 → 31/08/16

  Project: Research

• Penumbra and Recanalisation Acute Computed Tomography in Ischaemic Stroke Evaluation (PRACTISE)

  Wardlaw, J.

  Other

  1/06/13 → 30/11/18

  Project: Research

  • Evaluation Studies 100%
  • Multimodal Imaging 88%
  • Stroke 76%
  • Tomography 75%
  • Tissue Plasminogen Activator 71%

• Assessment of blood-brain barrier disruption using dynamic contrast-enhanced MRI. A systematic review

  Valdes Hernandez, M.

  1/06/13 → 12/07/13

  Project: MVM - (non-funded) undergraduate research project

  • Data Extraction 100%
  • Systematic Review 87%
  • Blood-Brain Barrier 61%
  • Disruption 59%
  • Systematic Reviews 46%

• Atlas-Based Assessment of Vascular Territories on Brain MR Images of Stroke Patients

  Valdes Hernandez, M.

  UK-based charities

  27/05/13 → 5/07/13

  Project: Research

  • Cerebral Small Vessel Diseases 100%
  • Stroke 70%
  • White Matter 31%
  • Brain 25%
  • Entropy 20%

• Unravelling the impact of dietary iodine exposure on brain structures and cognition in the elderly: a Study on a large Scottish Cohort

  Valdes Hernandez, M., Allan, J., Combet, E., Kyle, J. & Birch, F.

  1/01/13 → 31/12/13

  Project: Research Collaboration with external organisation

  • Dietary Exposure 100%
  • Iodine 76%
  • Cognition 58%
  • Parturition 51%
  • Fishes 45%

• Imaging Analysis Database Set-Up & Running Costs for the start-up phase of the PISTE Study

  Wardlaw, J.

  Other

  1/01/13 → 31/12/15

  Project: Research

• Improving Outcomes for Patients with Common Medical Disorders

  Wardlaw, J.

  UK-based charities

  1/11/12 → 31/10/15

  Project: Research

• MRI Study of Effect of Dignitana Device on Brain Temperature

  MacLeod, M., Marshall, I. & Wardlaw, J.

  EU other

  17/10/12 → 16/10/13

  Project: Research

• MRC CENTENERY EARLY CAREER RESEARH AWARD : ESTABLISHMENT OF NOVEL TECHNIQUES TO MEASURE VASCULAR REACTIVITY IN CEREBRAL AMALL VESSEL DISEASE

  Doubal, F.

  MRC

  1/10/12 → 31/08/13

  Project: Research

• Development of computational models for characterising atrophy of subcortical brain structures and ventricles

  Valdes Hernandez, M., Park, J. & Wardlaw, J.

  1/09/12 → 31/08/14

  Project: Research Collaboration with external organisation

  • Third Ventricle 100%
  • Hippocampus 98%
  • Independent Living 62%
  • Brain 59%
  • Atrophy 55%

• PhD Studentship - Shadia

  Pernet, C., Valdes Hernandez, M. & Wardlaw, J.

  UK-based charities

  1/08/12 → 31/10/18

  Project: Research

• Vacation Scholarship for Miss Dina Ghandour: Quantative Assessment of White Matter Lesion Volume Change in Longitdinal Studies

  Valdes Hernandez, M.

  UK-based charities

  4/06/12 → 13/07/12

  Project: Research

  • White Matter 100%
  • Magnetic Resonance Spectroscopy 92%
  • Brain 53%
  • Magnetic Resonance Imaging 9%
  • Independent Living 5%

• Computational methods to assess enlarged perivascular spaces - A systematic review and testing of key discriminants in a sample

  Valdes Hernandez, M., Wardlaw, J., Piper, R. J. & Wang, X.

  1/06/12 → 13/07/12

  Project: MVM - (non-funded) undergraduate research project

  • Glymphatic System 100%
  • Magnetic Resonance Spectroscopy 53%
  • Systematic Reviews 46%
  • Terminology 31%
  • White Matter 28%

• Is it possible to quantify mineral deposits in ageing brains in absence of T2*-weighted images?

  Valdes Hernandez, M.

  1/06/12 → 6/07/12

  Project: MVM - (non-funded) undergraduate research project

  • mineral deposit 100%
  • brain 83%
  • student 76%
  • tissue 65%
  • project 47%

• Establishment ofr novel techniques to measure vascualr reactivity un cerebal small vessel disease

  Doubal, F. & Deary, I.

  Other (Learned Society)

  1/06/12 → 30/09/13

  Project: Research

• UK BIOBANK OUTCOMES - PILOT STUDY

  Sudlow, C., Dennis, M., Salman, R., Wardlaw, J. & Wild, S.

  UK-based charities

  23/04/12 → 31/05/15

  Project: Research

  • Cerebral Hemorrhage 100%
  • Systematic Reviews 68%
  • Forests 27%
  • Meta-Analysis 17%
  • Guidelines 14%

• STANDARD FOR DTERMINING THE VASCULAR CONTRIBUTION TO NEURODEGENERATION

  Wardlaw, J.

  MRC

  1/03/12 → 31/08/13

  Project: Research

  • Neuroimaging 100%
  • Cerebral Small Vessel Diseases 94%
  • Lacunar Stroke 73%
  • varespladib methyl 57%
  • vascular factor 31%