Small Vessel Disease Research

Projects

Projects per year 2006 2010 2011 2012 2013 2015 2016 2017 2018 2019 2025

• 11 Active
• 129 Finished

Projects per year

Search results

• Finished

  RS MacDonald Seedcorn Fund

  McHutchison, C.

  14/10/19 → 30/09/20

  Project: University Awarded Project Funding

  • Amyotrophic Lateral Sclerosis 100%

• MRI biomarkers of cerebral small vessel disease (SVD) in rodent models in vivo

  Vallatos, A., Jansen, M., Stringer, M., Wardlaw, J. & Williams, A.

  UK-based charities

  1/09/19 → 1/06/22

  Project: Research

• Automated detection and classification of imaging features representative of acute ischaemic stroke on brain CT using computational deep learning

  Mair, G., Crowley, E., Storkey, A. & Wardlaw, J.

  UK-based charities

  4/03/19 → 31/10/20

  Project: Research

• Automated detection and classification of imaging features representative of acute ischaemic stroke on brain CT using computational deep learning

  Wardlaw, J., Crowley, E., Mair, G. & Storkey, A.

  UK-based charities

  4/03/19 → 31/10/20

  Project: Research

• Real-World Independent Testing of eASPECTS Software (RITeS)

  Mair, G., MacLeod, M., Salman, R., Sandercock, P. & Wardlaw, J.

  UK-based charities

  28/02/19 → 31/12/20

  Project: Research

• Does sleep and circadian rhythm disruption influence brain health?

  Breen, D., Chandran, S., Deary, I., Sudlow, C., Wardlaw, J. & Wilson, J.

  UK-based charities

  1/02/19 → 31/03/22

  Project: Research

• Retinal vascular changes in small vessel disease using optical coherence tomography angiography

  Wiseman, S., Dhillon, B., MacGillivray, T. & Wardlaw, J.

  MRC

  1/01/19 → 31/12/19

  Project: Research

• Advanced Magnetic Resonance Imaging techniques for diagnosis of cerebral microvascular dysfunction

  Marshall, I. & Wardlaw, J.

  UK-based charities

  1/10/18 → 30/09/22

  Project: Research

• Row Fogo Centre for Research into Ageing and the Brain

  Wardlaw, J.

  1/09/18 → 31/08/21

  Project: Other (Non-Funded/Miscellaneous)

  • Apathy 100%
  • White Matter 91%
  • Disease Progression 80%
  • Parturition 69%
  • Memory 32%

• Symptoms of SVD: identifying non-traditional neurological and cognitive symptoms of cerebral small vessel disease

  Clancy, U., Doubal, F. & Wardlaw, J.

  UK central government bodies/local authorities, health and hospital authorities

  1/08/18 → 30/09/21

  Project: Research

  • Apathy 100%
  • White Matter 91%
  • Disease Progression 80%
  • Parturition 69%
  • Memory 32%

• What is the best brain imaging strategy for patients with suspected minor stroke or transient ischaemic attack (TIA)?

  Whiteley, W., Dennis, M., MacLeod, M., Salman, R. & Wardlaw, J.

  UK central government bodies/local authorities, health and hospital authorities

  1/08/18 → 31/01/21

  Project: Research

• The eye and brain: Evaluation of the retinal nerve fibres and vessels as markers of small vessel disease progression or regression on neuroimaging

  Wiseman, S., Dhillon, B., Doubal, F., MacGillivray, T. & Wardlaw, J.

  UK-based charities

  1/07/18 → 30/06/22

  Project: Research

• Brain imaging and cognitive ageing in the Lothian Birth Cohort 1936: IV

  Wardlaw, J. & Bastin, M.

  MRC

  1/05/18 → 30/04/21

  Project: Research

• Magnetic resonance imaging (MRI) of brain vascular changes and white matter hyperintensities (WMH) in humans

  Meijboom, R., Thrippleton, M., Waldman, A. & Wardlaw, J.

  MRC

  1/04/18 → 31/03/19

  Project: Research

• Neuro-Inflammation after Cerebral Haemorrhage In Edinburgh (NICHE)

  Salman, R., Hughes, J., McColl, B., Norrie, J., Rodrigues, M., Samarasekera, N., Smith, C., Wardlaw, J. & Williams, A.

  UK-based charities

  1/04/18 → 31/03/22

  Project: Research

• Tracking progression from normal to pathological ageing using neuroimaging markers

  Valdes Hernandez, M. & Parra, M. A.

  1/01/18 → 31/03/18

  Project: University Awarded Project Funding

  • Atrophy 100%
  • Gray Matter 46%
  • Brain 33%
  • Globus Pallidus 26%
  • Corpus Striatum 22%

• Neurodegeneration in Huntington disease: unveiling neural correlates of neurocognitive dysfunction

  Valdes Hernandez, M., Parra, M. A. & Priller, J.

  1/01/18 → 31/03/18

  Project: University Awarded Project Funding

  • Huntington Disease 100%
  • Gray Matter 91%

• Striatal Brain Iron Deposition, Microbleeds and Cognition 1 year after Minor Ischaemic Stroke

  Valdes Hernandez, M., Wardlaw, J. & Doubal, F.

  1/01/18 → 31/03/18

  Project: University Awarded Project Funding

  • benzo(g)isoquinoline-5,10-dione 100%
  • Corpus Striatum 80%
  • Iron 34%
  • Cognition 32%
  • Stroke 28%

• Structural, functional and metabolic brain differences between groups with opposite sexual attitudes. A systematic review of the neuroimaging literature

  Valdes Hernandez, M.

  1/01/18 → 31/07/18

  Project: University Awarded Project Funding

  • homosexuality 100%
  • brain 85%
  • neurosciences 49%
  • Group 30%
  • gender 24%

• Maximising a Small Vessel Disease Brain Bank Resource

  Smith, C., Salman, R. & Wardlaw, J.

  UK-based charities

  1/12/17 → 31/12/21

  Project: Research

• LIFT: Delineating the Neural Mediators of Rheumatoid Arthritis Related Fatigue (LIFT Trial Add-On)

  Wiseman, S. & Wardlaw, J.

  UK central government bodies/local authorities, health and hospital authorities

  1/10/17 → 30/09/20

  Project: Other (Non-Funded/Miscellaneous)

• Rates, Risks and Routes to Reduce Vascular Dementia (R4VaD)

  Wardlaw, J.

  UK-based charities

  1/10/17 → 30/06/19

  Project: Research

  • Biobank 100%
  • Brain 89%
  • Brain Imaging 79%
  • vascular factor 72%
  • White Matter 64%

• Maximising a small vessel disease brain bank resource

  Smith, C., Salman, R. & Wardlaw, J.

  MRC

  29/09/17 → 28/03/21

  Project: Research

• Delineating the neural mediators of rheumatoid arthritis related fatigue

  Wiseman, S. & Wardlaw, J.

  1/08/17 → 30/09/20

  Project: Research

• Develop Sensitive Behavioural And Neuroimaging Markers In Detecting Cognitive Ageing

  Wang, S. & Valdes Hernandez, M.

  BBSRC

  4/04/17 → 25/04/19

  Project: Research

  • Magnetic resonance imaging 100%
  • Magnetic resonance 99%
  • Gray Matter 97%
  • Magnetic Resonance Spectroscopy 91%
  • Short-Term Memory 89%

• Develop sensitive behavioural and neuroimaging markers in detecting cognitive ageing

  Valdes Hernandez, M., Wang, S., Tavares, A. & Holmes, M.

  1/04/17 → 31/03/19

  Project: Research Collaboration with external organisation

• LACI-2 Trial

  Wardlaw, J., Cvoro, V., Dennis, M. & Doubal, F.

  UK-based charities

  1/03/17 → 28/02/21

  Project: Research

• On the intelligence of men and women: A systematic review on gender differences on brain MRI structures and connectivity

  Valdes Hernandez, M.

  1/01/17 → 31/03/17

  Project: University Awarded Project Funding

  • brain 100%
  • gender-specific factors 71%
  • honor 30%
  • integrity 25%
  • literature 24%

• Can subtle changes in global atrophy and the superior frontal gyrus be indicative of the differences between cognitive groups in late adulthood?

  Valdes Hernandez, M.

  1/01/17 → 31/03/17

  Project: University Awarded Project Funding

  • Adulthood 100%
  • Medical Sciences 98%
  • Indicative 91%

• An evidence-based evaluation of the clinical and cost effectiveness of foot ulcer risk assessment and structured care interventions for people with diabetes.

  Chappell, F.

  Other

  1/01/17 → 31/12/18

  Project: Research

• Network for the development, validation and implementation of new methods to measure vascular dysfunction in dementia

  Smith, C. & Wardlaw, J.

  UK-based charities

  1/10/16 → 31/03/19

  Project: Research

• Centre for Cognitive Ageing and Cognitive Epidemiology Phase 2 PILOTS BUDGET (Genotyping and Brain Imaging).

  Wardlaw, J.

  MRC

  1/10/16 → 31/08/19

  Project: Research

• Dementias Platform UK MR-PET Partnership

  Wardlaw, J.

  Other

  28/09/16 → 27/09/21

  Project: Research

• Evaluation of computational methods for estimating the cortical stroke lesion evolution from magnetic resonance images.

  Valdes Hernandez, M.

  UK-based charities

  31/05/16 → 25/07/16

  Project: Research

• BRIDGET - BRain Imaging, cognition, Dementia and next generation GEenomics

  Deary, I., Bastin, M., Luciano, M., Prendergast, J. & Wardlaw, J.

  MRC

  1/05/16 → 31/10/19

  Project: Research

  • Diffusion Tensor Imaging 100%
  • human population 95%
  • polymorphism 93%
  • mutation 88%
  • single nucleotide polymorphism 82%

• Enhanced Control of Hypertension and Thrombolysis Stroke Study (STAY ENCHANTED)

  Wardlaw, J.

  Other

  1/04/16 → 1/10/18

  Project: Research

  • Stroke 100%
  • Blood Pressure 93%
  • Tissue Plasminogen Activator 52%
  • Guidelines 41%
  • Intracranial Hemorrhages 27%

• The Disconnected Mind Phase 3

  Wardlaw, J.

  UK-based charities

  1/04/16 → 30/09/20

  Project: Research

  • Parturition 100%
  • White Matter 65%
  • DNA Methylation 51%
  • Cognitive Aging 48%
  • Genome-Wide Association Study 46%

• Feasibility study of obtaining high-resolution spectroscopy images using data fusion techniques

  Valdes Hernandez, M. & Ozturk-Isik, E.

  UK-based charities

  15/03/16 → 14/03/17

  Project: Research

  • Magnetic resonance 100%
  • Convolutional neural networks 87%
  • Magnetic Resonance Spectroscopy 81%
  • Imaging techniques 73%
  • Education 60%

• Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST 2)

  Wardlaw, J.

  UK-based charities

  1/02/16 → 30/11/22

  Project: Research

• SVDs-at-target: Small vessel diseases in a mechanistic perspective: Targets for Intervention Affected pathways and mechanistic exploitation for prevention of stroke and dementia

  Wardlaw, J.

  EU government bodies

  1/01/16 → 31/12/21

  Project: Research

  • White Matter 100%
  • Stroke 86%
  • Cerebral Small Vessel Diseases 71%
  • Brain 45%
  • Lacunar Stroke 44%

• DPUK-IMAGING INFORMATICS

  Gourley, C., Job, D. & Wardlaw, J.

  Other

  1/01/16 → 8/07/17

  Project: Research

• Accuracy, pattern and possible underlying factors of brain microbleeds progression on older adults with absence or mild presence of vascular pathology

  Valdes Hernandez, M.

  1/01/16 → 31/03/16

  Project: University Awarded Project Funding

  • Pathology 100%
  • Blood Vessels 93%
  • Magnetic Resonance 82%
  • Brain 77%
  • Cholesterol 72%

• Small vessel disease pathophysiology: human postmortem brain tissue study with clinical radiological pathological correlation - Fellowship for Catherine Humphreys

  Wardlaw, J. & Smith, C.

  UK-based charities

  1/12/15 → 31/12/19

  Project: Research

• ECAT (203699) Multi-modality imaging assessment of cerebral small vessel disease biomarkers after stroke due to spontaneous intracerebral haemorrhage

  Wardlaw, J. & Salman, R.

  UK-based charities

  1/12/15 → 30/11/18

  Project: Research

  • Cerebral Amyloid Angiopathy 100%
  • Cerebral Hemorrhage 76%
  • systematic review 45%
  • meta-analysis 40%
  • Routine Diagnostic Tests 38%

• Row Fogo Charitable Trust Funds

  Wardlaw, J.

  UK-based charities

  1/10/15 → 30/09/18

  Project: Research

  • White Matter 100%
  • Cerebral Small Vessel Diseases 80%
  • Stroke 47%
  • Brain 42%
  • Aptitude 38%

• Preventing cognitive decline and dementia from cerebral microvascular disease

  Wardlaw, J.

  UK-based charities

  1/10/15 → 31/07/18

  Project: Research

  • isosorbide-5-mononitrate 100%
  • Cerebral Small Vessel Diseases 94%
  • Cilostazol 94%
  • Lacunar Stroke 85%
  • Dementia 53%

• Equipment Grant - MR Scanner

  Wardlaw, J.

  UK-based charities

  1/08/15 → 31/07/20

  Project: Research

• Senior Clinical Lectureship: A platform for patient focused trials to prevent cerebral small vessel disease

  Doubal, F.

  UK-based charities

  1/06/15 → 31/05/21

  Project: Research

  • isosorbide-5-mononitrate 100%
  • Cerebral Small Vessel Diseases 94%
  • Cilostazol 94%
  • Lacunar Stroke 93%
  • Stroke 74%

• Right-2 Imaging Resources - Rapid Intervention With Glyceryl Trinitrate In Hypertensive Stroke Trial-2 (Right-2)

  Wardlaw, J.

  Other

  1/05/15 → 31/10/18

  Project: Research

  • isosorbide-5-mononitrate 100%
  • Cilostazol 94%
  • Lacunar Stroke 85%
  • Ambulances 77%
  • Nitroglycerin 73%

• Brain imaging and cognitive ageing in the Lothian Birth Cohort 1936: III

  Wardlaw, J., Bastin, M. & Deary, I.

  MRC

  1/05/15 → 30/04/19

  Project: Research

  • White Matter 100%
  • Parturition 92%
  • Brain 88%
  • Aptitude 63%
  • Intelligence 47%