SynthSys

Organization profile

Organisation profile

Edinburgh’s Centre for Synthetic and Systems Biology (known as SynthSys) embraces a vibrant community of > 50 research groups and >200 researchers. Our research is broad and deep, addressing a diversity of scientific questions with wide ranging impacts for society, industry, the economy and our planet.

Synthetic and systems biology spans biology, chemistry, physics, informatics, social sciences, engineering, medicine and veterinary sciences. Our researchers explore fundamental biological questions about living cells and systems and apply these insights – often in collaboration with industry – to create innovations for many markets including industrial biotechnology (including bioremediation and biofuels), agriculture, the environment, and medicine and healthcare. In October 2015, we opened the UK Centre for Mammalian Synthetic Biology funded by the BBSRC/EPSRC/MRC as part of the UK Research Councils' Synthetic Biology for Growth programme. This Centre brings together our research in synthetic biology as applied to medicine and healthcare.

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Helen Alexander
- School of Biological Sciences - Royal Society University Research Fellow
- SynthSys
Person: Academic: Research Active
Rosalind Allen
- rosalind.allen@ed.ac.uk
- School of Physics and Astronomy - Personal Chair of Biological Physics
- SynthSys
Person: Academic: Research Active
Robin Allshire
- School of Biological Sciences - Professor of Chromosome Biology
- SynthSys
Person: Academic: Research Active

Action Sequencing Using Visual Permutations
Burke, M., Subr, K. & Ramamoorthy, S., 1 Apr 2021, In: IEEE Robotics and Automation Letters. 6, 2, p. 1745-1752 8 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Affordance-Aware Handovers With Human Arm Mobility Constraints
Ardón, P., Cabrera, M. E., Pairet, È., Petrick, R. P. A., Ramamoorthy, S., Lohan, K. S. & Cakmak, M., 1 Apr 2021, In: IEEE Robotics and Automation Letters. 6, 2, p. 3136-3143 8 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
A metabolomics-based approach to identify lineage guiding molecules in Pericyte cultures
Alakpa, E. V., West, C. C., Goldie, L., Harper, M. M., Burgess, K., Ulijn, R. V. & Dalby, M. J., 13 Feb 2021, Pericytes : Methods and Protocols. Humana Press, Vol. 2235. p. 47-59 13 p. (Pericytes; vol. 2235).
Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Invited talk

Analysis of DNA Methylation Data: a Kernel-based Approach
Tom Mayo (Speaker)
2014
Activity: Academic talk or presentation types › Invited talk

1 Active

Award value: £15,000.00. Bio-automation network
Rios Solis, L.
1/06/19 → 1/06/21
Project: University Awarded Project Funding

A system for in vivo ablation of MeCP2-deficient neurons in the Rett Syndrome mouse model
Paton, K. (Owner), Selfridge, J. (Creator), Guy, J. (Researcher), Connelly, J. (Researcher), Waterfall, M. (Researcher), Kelly, D. (Researcher), Davies, J. (Supervisor), Smith, A. (Supervisor), Rosser, S. (Supervisor), Bird, A. (Owner), Romanowski, A. (Data Manager), Zielinski, T. (Data Manager) & Paton, K. (Owner), Edinburgh DataVault, 30 Apr 2021
DOI: 10.7488/139e57b5-25ed-4ad2-b9bc-d323305ede21
Dataset
Data from Maturation of the 90S pre-ribosome requires Mrd1 dependent U3 snoRNA and 35S pre-rRNA structural rearrangements
Granneman, S. (Creator), National Center for Biotechnology Information (Gene Expression Omnibus), 15 Jan 2018
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE106868
Dataset
Numerical data from "Spontaneous spatiotemporal waves of gene expression from biological clocks in the leaf", Wenden, Toner et al. PNAS 2012, 109: 6757-6762
Wenden, B. (Creator), Toner, D. L. K. (Creator), Hodge, S. (Creator), Grima, R. (Creator) & Millar, A. (Creator), University of Edinburgh, 2012
DOI: 10.1073/pnas.1118814109, http://www.biodare.ed.ac.uk/robust/ShowExperiment.action?experimentId=13394437504756 and 10 more links, http://www.biodare.ed.ac.uk/robust/ShowExperiment.action?experimentId=13394446996851, http://www.biodare.ed.ac.uk/robust/ShowExperiment.action?experimentId=13394434885385, http://www.biodare.ed.ac.uk/robust/ShowExperiment.action?experimentId=13394443003897, http://www.biodare.ed.ac.uk/robust/ShowExperiment.action?experimentId=13394444364628, http://www.biodare.ed.ac.uk/robust/ShowExperiment.action?experimentId=13394446929060, http://www.biodare.ed.ac.uk/robust/ShowExperiment.action?experimentId=13394446784669, http://www.biodare.ed.ac.uk/robust/ShowExperiment.action?experimentId=13394379875121, http://www.biodare.ed.ac.uk/robust/ShowExperiment.action?experimentId=13394383188744, http://www.biodare.ed.ac.uk/robust/ShowExperiment.action?experimentId=13394381111502, http://www.biodare.ed.ac.uk/robust/ShowExperiment.action?experimentId=13394382079593 (show fewer)
Dataset