Alan Serrels

MR.

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25 Article
2 Meeting abstract

T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity
Canel, M., Taggart, D., Sims, A. H., Lonergan, D. W., Waizenegger, I. C. & Serrels, A., 21 Jan 2020, In: eLIFE. 9, e48092.
Research output: Contribution to journal › Article › peer-review

Open Access
Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy
Findlay, E. G., Currie, A. J., Zhang, A., Ovciarikova, J., Young, L., Stevens, H., McHugh, B. J., Canel, M., Gray, M., Milling, S. W. F., Campbell, J. D. M., Savill, J., Serrels, A. & Davidson, D. J., 1 May 2019, In: OncoImmunology. p. 1-17
Research output: Contribution to journal › Article › peer-review

Open Access
File
Development of a fluorescence-based cellular apoptosis reporter
Balderstone, L. A., Dawson, J., Welman, A., Serrels, A., Wedge, S. R. & Brunton, V., 24 Oct 2018, In: Methods and Applications in Fluorescence.
Research output: Contribution to journal › Article › peer-review

Open Access
File
High-Precision Photothermal Ablation using Biocompatible Palladium Nanoparticles and Laser Scanning Microscopy
Rubio Ruiz, B., Pérez-López, A. M., Bray, T. L., Lee, M., Serrels, A., Prieto, M., Arruebo, M., Carragher, N. O., Sebastián, V. & Unciti-Broceta, A., 10 Jan 2018, In: ACS Applied Materials & Interfaces.
Research output: Contribution to journal › Article › peer-review

Open Access
File
1211TiPFAK-PD1: a phase I/IIa trial of FAK (defactinib) & PD-1 (pembrolizumab) inhibition
Symeonides, S., Evans, T. R. J., Coyle, V., Serrels, A., Thomson, F., Currie, D., Dillon, S., Paul, J., Fennell, D. A. & Ottensmeier, C., 1 Sep 2017, In: Annals of Oncology. 28, suppl_5
Research output: Contribution to journal › Meeting abstract › peer-review

3 Active
4 Finished

Defining the mechanistic role of Kynurenine-3-monooxygenase in breast cancer
Mole, D., Mackay, L., Serrels, A. & Sims, A.
UK central government bodies/local authorities, health and hospital authorities
1/08/19 → 31/07/22
Project: Research
Defining the mechanisms of FAK-dependent immune evasion in Pancreatic Cancer
Serrels, A.
UK-based charities
1/10/18 → 30/09/24
Project: Research
FAK-PD1 - Aphase I/II Study to Assess Safety, Tolerability and Preliminary Activity of the Combination of FAK and PD-1 Inhibitioin in Patients with Advanced Solid Malignancies....
Serrels, A.
Other
1/01/16 → 31/10/23
Project: Research
KMO-PET: A radiotracer against kynurenine-3-monooxygenase for positron emission tomography imaging in cancer and endometriosis
Mole, D., Horne, A., Saunders, P. & Serrels, A.
MRC
1/02/19 → 31/10/19
Project: Research
Inflammatory mechanisms to suppress Treg cell function in cancer
Anderton, S. & Serrels, A.
UK-based charities
1/11/16 → 30/04/20
Project: Research

Imaging Drug Uptake by Bioorthogonal Stimulated Raman Scattering Microscopy
Tipping, W. (Creator), Lee, M. (Creator), Serrels, A. (Creator), Brunton, V. (Creator) & Hulme, A. (Creator), Edinburgh DataShare, 18 May 2017
DOI: 10.7488/ds/2046
Dataset

New drugs could help body's immune system beat cancer, says Dr Alan Serrels
Alan Serrels
25/09/15
8 items of Media coverage
Press/Media: Research