Alba Abad Fernandez

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5 Article

Rules of engagement for condensins and cohesins guide mitotic chromosome formation
Samejima, K., Gibcus, J. H., Abraham, S., Cisneros-Soberanis, F., Samejima, I., Beckett, A. J., Pucekova, N., Abad, M. A., Abad, M. A., Spanos, C., Medina-Pritchard, B., Paulson, J. R., Xie, L., Jeyaprakash, A. A., Prior, I. A., Mirny, L. A., Dekker, J., Goloborodko, A. & Earnshaw, W. C., 11 Apr 2025, In: Science. 388, 6743, 23 p., eadq1709 .
Research output: Contribution to journal › Article › peer-review

Open Access
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RNA methyltransferase SPOUT1/CENP-32 links mitotic spindle organization with the neurodevelopmental disorder SpADMiSS
Dharmadhikari, A. V., Abad, M. A., Khan, S., Maroofian, R., Sands, T. T., Ullah, F., Samejima, I., Shen, Y., Wear, M. A., Moore, K. E., Kondakova, E., Mitina, N., Schaub, T., Lee, G. K., Umandap, C. H., Berger, S. M., Iglesias, A. D., Popp, B., Abou jamra, R. & Gabriel, H. & 62 others, Rentas, S., Rippert, A. L., Gray, C., Izumi, K., Conlin, L. K., Koboldt, D. C., Mosher, T. M., Hickey, S. E., Albert, D. V. F., Norwood, H., Lewanda, A. F., Dai, H., Liu, P., Mitani, T., Marafi, D., Eker, H. K., Pehlivan, D., Posey, J. E., Lippa, N. C., Vena, N., Heinzen, E. L., Goldstein, D. B., Mignot, C., De sainte agathe, J.-M., Al-Sannaa, N. A., Zamani, M., Sadeghian, S., Azizimalamiri, R., Seifia, T., Zaki, M. S., Abdel-Salam, G. M. H., Abdel-Hamid, M. S., Alabdi, L., Alkuraya, F. S., Dawoud, H., Lofty, A., Bauer, P., Zifarelli, G., Afzal, E., Zafar, F., Efthymiou, S., Gossett, D., Towne, M. C., Yeneabat, R., Perez-Duenas, B., Cazurro-Gutierrez, A., Verdura, E., Cantarin-Extremera, V., Marques, A. D. V., Helwak, A., Tollervey, D., Wontakal, S. N., Aggarwal, V. S., Rosenfeld, J. A., Tarabykin, V., Ohta, S., Lupski, J. R., Houlden, H., Earnshaw, W. C., Davis, E. E., Jeyaprakash, A. A. & Liao, J., 17 Feb 2025, In: Nature Communications. 16, 1, 24 p., 1703.
Research output: Contribution to journal › Article › peer-review

Open Access
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Small changes in phospho-occupancy at the kinetochore–microtubule interface drive mitotic fidelity
Kucharski, T. J., Hards, R., Vandal, S. E., Abad, M. A., Jeyaprakash, A. A., Kaye, E., Al-Rawi, A., Ly, T., Godek, K. M., Gerber, S. A. & Compton, D. A., 25 Jul 2022, In: Journal of Cell Biology. 221, 9, 34 p., e202107107.
Research output: Contribution to journal › Article › peer-review

Open Access
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Aneuploidy in cancer: Lessons from acute lymphoblastic leukemia
Molina, O., Abad, M. A., Solé, F. & Menéndez, P., 1 Jan 2021, In: Trends in Cancer. 7, 1, p. 37-47 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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Structural basis for centromere maintenance by Drosophila CENP-A chaperone CAL1
Medina-Pritchard, B., Lazou, V., Zou, J., Byron, O., Abad Fernandez, M., Rappsilber, J., Heun, P. & Arulanandam, J., 5 Mar 2020, In: EMBO Journal. e103234.
Research output: Contribution to journal › Article › peer-review

Open Access
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Fig.S16 SDS-PAGE analysis of size exclusion chromatography profiles for SPOUT1/CENP-32 WT and SPOUT1/CENP-32 patient variants proteins
Abad Fernandez, A. (Creator), Figshare, 27 Nov 2024
DOI: 10.6084/m9.figshare.26842024.v1
Dataset
PDB ID 8QSW: Crystal structure of SPOUT1/CENP-32 | A356N catalytic site mutant
Arulanandam, J. (Creator) & Abad Fernandez, A. (Creator), RCSB Protein Data Bank, 23 Oct 2024
DOI: 10.2210/pdb8QSW/pdb
Dataset
Fig.S13 SDS-PAGE analysis of SPOUT1/CENP-32 71
Abad Fernandez, A. (Creator), Figshare, 27 Nov 2024
DOI: 10.6084/m9.figshare.26841652.v1
Dataset
PDB ID 8QSU: Crystal structure of SPOUT1/CENP-32 bound to SAH
Arulanandam, J. (Creator) & Abad Fernandez, A. (Creator), RCSB Protein Data Bank, 23 Oct 2024
DOI: 10.2210/pdb8QSU/pdb
Dataset
Fig.6C Uncropped immunofluorescence images of SPOUT1/CENP-32
Abad Fernandez, A. (Creator), Figshare, 27 Nov 2024
DOI: 10.6084/m9.figshare.26841544.v1
Dataset

Alba Abad Fernandez

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Collaborations and top research areas from the last five years

Dive into details

Rules of engagement for condensins and cohesins guide mitotic chromosome formation

RNA methyltransferase SPOUT1/CENP-32 links mitotic spindle organization with the neurodevelopmental disorder SpADMiSS

Small changes in phospho-occupancy at the kinetochore–microtubule interface drive mitotic fidelity

Aneuploidy in cancer: Lessons from acute lymphoblastic leukemia

Structural basis for centromere maintenance by Drosophila CENP-A chaperone CAL1

Fig.S16 SDS-PAGE analysis of size exclusion chromatography profiles for SPOUT1/CENP-32 WT and SPOUT1/CENP-32 patient variants proteins

PDB ID 8QSW: Crystal structure of SPOUT1/CENP-32 | A356N catalytic site mutant

Fig.S13 SDS-PAGE analysis of SPOUT1/CENP-32 71

PDB ID 8QSU: Crystal structure of SPOUT1/CENP-32 bound to SAH

Fig.6C Uncropped immunofluorescence images of SPOUT1/CENP-32

Alba Abad Fernandez

Fingerprint

Collaborations and top research areas from the last five years

Research output

Datasets