Alexander Medvinsky

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  Analysis of biomarkers in cryopreserved remnants of umbilical cord blood samples to test predictors of regenerative potential

  Medvinsky, A.

  UK-based charities

  1/02/22 → 31/03/23

  Project: Research

• Analysis of biomarkers in cryopreserved remnants of umbilical cord blood samples to test predictors of regenerative potential

  Medvinsky, A.

  Wellcome Trust (Rcl)

  1/02/22 → 1/12/23

  Project: Research

• Retrospective analysis of genetic markers in frozen cord blood residues to predict the success of hematopoietic transplants in the clinic

  Medvinsky, A.

  UK-based charities

  1/10/21 → 31/10/21

  Project: Research

• A bioengineering platform for the multiparametric and quantitative control of the cell environment across scales

  Blin, G. & Medvinsky, A.

  BBSRC

  1/11/20 → 30/06/21

  Project: Research

• IDENTIFICATION OF A NOVEL ANGIOPOIETIN 2 SIGNALLING CENTRE IN THE EMBRYONIC HAEMATOPOIETIC STEM CELL NICHE

  Medvinsky, A.

  MRC

  1/06/18 → 31/05/21

  Project: Research

• Japan Partnering Award: Gene regulatory networks in stem cells and primordial germ cells

  Chambers, I., Blackburn, C., Kunath, T., Lowell, S., Medvinsky, A., O'Carroll, D., Rosser, S., Soufi, A. & Wilson, V.

  BBSRC

  1/08/16 → 31/05/23

  Project: Research

  • Embryonic Stem Cell 100%
  • Protein 40%
  • Stem Cell 40%
  • Epiblast 40%
  • Self Concept 40%

• Developing Novel Methodology For Identification of Umbilical Cord Blood Grafts With Rapid Long-term Haematopoietic Reconstitution

  Medvinsky, A.

  UK central government bodies/local authorities, health and hospital authorities

  1/11/15 → 31/10/18

  Project: Research

• Tracking the embryonic origin of the adult haematopoietic system

  Medvinsky, A.

  MRC

  1/09/14 → 30/11/18

  Project: Research

• ECAT (100468) Analysis of the early development of human haematopoietic stem and progenitor cells

  Medvinsky, A.

  UK-based charities

  6/05/13 → 8/10/17

  Project: Research

  • Hematopoietic Stem Cell 100%
  • Development 71%
  • Stem Cell 71%
  • Maturation 42%
  • Precursor 35%

• MRC Studentship: A Batsivari

  Medvinsky, A.

  MRC

  1/05/13 → 30/09/14

  Project: Research

• Comparative analysis of HSCs emerging in the human embryonic AGM region and umbilical cord blood1265

  Medvinsky, A.

  UK-based charities

  1/01/13 → 31/12/15

  Project: Research

• VESSEL: Vascular Endothelial Interactions and Specialization

  Medvinsky, A.

  EU government bodies

  1/01/13 → 31/12/16

  Project: Research

• VESSEL: Vascular Endothelial Interactions and Specialization

  Medvinsky, A.

  EU government bodies

  1/01/13 → 31/12/16

  Project: Research

• Development of a non-invasive strategy enhancing haematopoietic stem cell potential of human umbilical cord cells

  Medvinsky, A.

  MRC

  1/07/11 → 30/04/15

  Project: Research

  • Hematopoietic Stem Cell 100%
  • Stem Cell 100%
  • Analysis 100%
  • Human Embryo 100%
  • Development 100%

• Analysis of mechanisms of early haematopoietic stem cell development controlled by FLK1/SCL regulatory network

  Medvinsky, A.

  MRC

  30/09/10 → 30/01/15

  Project: Research

  • Hematopoietic Stem Cell 100%
  • CD43 50%
  • Interleukin 3 50%
  • Precursor 50%
  • Phenotype 50%

• A Glycosomal signalling pathway regulating trypanosome development

  Medvinsky, A.

  UK-based charities

  1/09/10 → 28/02/14

  Project: Research

• Identification of functional domains in the AGM region linked to the hierarchical organisation of the developing haematopoietic stem cell lineage

  Medvinsky, A.

  BBSRC

  1/01/10 → 31/12/13

  Project: Research

  • Hematopoietic Stem Cell 100%
  • Precursor 50%
  • Cell Lineage 28%
  • Screening 25%
  • Embryonic Stem Cell 25%

• Purchase of a FACS Cell Sorter and a LSR11 Flow Cytometer

  Chambers, I., Blackburn, C., Brickman, J., Medvinsky, A. & Nerlov, C.

  UK-based charities

  1/09/09 → 31/07/14

  Project: Research

• Notch Signalling in developmental Specification of Haematopoietic stem cells

  Medvinsky, A.

  UK-based charities

  23/03/09 → 22/09/13

  Project: Research

• Directing differentiation of mouse and human embryonic stem cells into haematopoietic stem cells

  Medvinsky, A.

  UK-based charities

  1/01/09 → 31/12/14

  Project: Research

• NotchIT: Notch signalling in Development and Pathology

  Medvinsky, A.

  EU government bodies

  1/01/09 → 31/12/12

  Project: Research

• Ex Vivo expansion of human haematopoietic stem cells

  Medvinsky, A.

  UK-based charities

  1/07/08 → 30/06/11

  Project: Research

• Purchase of gamma irradiators

  Medvinsky, A., Allen, J., Anderton, S., Blackburn, C. & Gray, D.

  UK-based charities

  1/07/08 → 30/06/11

  Project: Research

• Expansion of haematopoietic strem cells (HSCs).

  Medvinsky, A.

  UK central government bodies/local authorities, health and hospital authorities

  1/02/08 → 30/06/08

  Project: Research

• Analysis of cellular mechanisms underlying haematopoietic stem cell (HSC) development using a novel in vitro system

  Medvinsky, A.

  BBSRC

  1/07/06 → 30/06/09

  Project: Research

  • Hematopoietic Stem Cell 100%
  • Mouse 55%
  • Aorta-Gonad-Mesonephros 43%
  • Development 40%
  • Analysis 33%

• Role of AML1/Runx isoforms in development, self-renewal & differentiation of haematopoietic progenitor/stem cells.

  Medvinsky, A.

  MRC

  1/05/06 → 30/04/09

  Project: Research

• Ontogeny of haematopoietic stem cells

  Medvinsky, A.

  UK-based charities

  1/05/06 → 30/06/09

  Project: Research

• Analysis of haematopoietic stem cell development using Flk- GFP reporter mice

  Medvinsky, A.

  UK-based charities

  1/08/05 → 15/07/09

  Project: Research

• Role of HoxB4 & analysis of its cell targets in haematopoietic development

  Medvinsky, A.

  UK-based charities

  1/04/05 → 15/05/09

  Project: Research

• AMLI/Runx1 in development of haematopoietic stem cells

  Medvinsky, A.

  Non-EU-based charities

  1/04/04 → 31/03/06

  Project: Research

• EUROSTEMCELL: Training Budget

  Smith, A., Medvinsky, A. & Nerlov, C.

  EU government bodies

  1/02/04 → 31/01/08

  Project: Research

  • Thymus 100%
  • Cells 100%
  • Stem Cell 25%
  • Cell Population 12%
  • T Cell Development 12%

• The role of AML1 in mesenchymal stem cells and stromal lines derived from adult bone marrow and embryonic AGM

  Medvinsky, A. & Horsburgh, K.

  UK-based charities

  1/01/03 → 30/09/05

  Project: Research

• Role of AML1/CBFa2/Runtx1 in embryonic development of haematopoietic

  Medvinsky, A.

  MRC

  12/08/02 → 11/08/05

  Project: Research

• Identification of the molecular mechanism underlying the initiation and expansion of HSCs in the mouse embryo

  Medvinsky, A.

  Non-EU industry, commerce and public corporations

  1/02/01 → 31/01/02

  Project: Research

• Generation of mice for efficient derivation of conditionally immortalised cell lines of haemopoietic progenitors

  Medvinsky, A.

  UK-based charities

  15/01/00 → 1/06/04

  Project: Research

• Role of CD44 Surface Receptors in Embryonic Development

  Medvinsky, A.

  UK-based charities

  1/04/99 → 6/06/04

  Project: Research

• Identification of genes involved in haematopoietic stem cell differentiation during embryonic development of the mouse

  Medvinsky, A.

  BBSRC

  19/10/98 → 18/10/01

  Project: Research

• The analysis of cell fate and migration mechanisms during development of the haematopietic system of the mouse.

  Medvinsky, A.

  MRC

  1/10/98 → 31/03/04

  Project: Research

• Differentiation & development of murine embryonic haematopoietic stem cells

  Ansell, J. & Medvinsky, A.

  UK-based charities

  1/05/97 → 31/07/02

  Project: Research