Research output per year
Research output per year
Personal profile
Biography
Biochemist
Joint Honours degree in Pharmacology and Biochemistry (King's College, University of London)
MSc in Clinical Biochemistry (Newcastle University)
PhD "Use of brain-specific proteins in the diagnosis of dementia" (National Hospital for Neurology, London; University College, London)
Creation of an analytical and interpretation diagnostic service for cerebrospinal fluid (CSF) 14-3-3 and other proteins for diagnosis of Creutzfeldt-jakob disease (CJD) within the National CJD Research & Surveillance Unit (NCJDRSU) at University of Edinburgh
Development of protein aggregation assays for the diagnosis of CJD, Lewy body dementia, Parkinson's disease and other neurodegenerative dementias
Qualifications
BSc: Biochemistry/Pharmacolgy 2i (King's College, London) (1983)
MSc: Clinical Chemistry (Newcastle University) (1984)
PhD: "Use of brain-specific proteins in the diagnosis of dementia" (University College, London) (1999)
Fellow of Royal College of Pathologists (2002)
Current Research Interests
Use of CSF 14-3-3 and S100b in the diagnosis of patients with suspected CJD
Development of Real-time Quaking Induced Conversion (RT-QuIC) as a diagnostic tool for CJD
CSF tau, p-tau and amyloid proteins in the differentaion diagnosis of dementia
Development of protein aggregation assays for the diagnosis of Parkinson's disease and Lewy body dementia and other neurodegenerative diseases
Development and Evaluation of Protein aggregations assays in the diagnosis of patients with CJD
Fingerprint
Dive into the research topics where Alison Green is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 28 Similar Profiles
Network
Recent external collaboration on country level. Dive into details by clicking on the dots or
Research output
-
Regional Differences in Neuroinflammation-Associated Gene Expression in the Brain of Sporadic Creutzfeldt–Jakob Disease Patients
Areškevičiūtė, A., Litman, T., Broholm, H., Melchior, L. C., Nielsen, P. R., Green, A., Eriksen, J. O., Smith, C. & Lund, E. L., 25 Dec 2020, In: International Journal of Molecular Sciences. 22, 1, p. 140Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Ring trial of 2nd generation RT‐QuIC diagnostic tests for sporadic CJD
Orrú, C. D., Groveman, B. R., Foutz, A., Bongianni, M., Cardone, F., Mckenzie, N., Culeux, A., Poleggi, A., Grznarova, K., Perra, D., Fiorini, M., Liu, X., Ladogana, A., Sbriccoli, M., Hughson, A. G., Haïk, S., Green, A. J., Geschwind, M. D., Pocchiari, M., Safar, J. G. & 2 others, , 7 Nov 2020, In: Annals of Clinical and Translational Neurology. 7, 11, p. 2262-2271Research output: Contribution to journal › Article › peer-review
Open AccessFile -
RT-QuIC-based detection of alpha-synuclein seeding activity in brains of dementia with Lewy Body patients and of a transgenic mouse model of synucleinopathy
Han, J., Jang, H., Green, A. J. E. & Choi, Y. P., 10 Feb 2020, In: Prion. 14, 1, p. 88-94Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Comparative study of cerebrospinal fluid α-synuclein seeding aggregation assays for diagnosis of Parkinson's disease: CSF α-SYNUCLEIN SEEDING AGGREGATION FOR PD DIAGNOSIS
Kang, U. J., Boehme, A. K., Fairfoul, G., Shahnawaz, M., Ma, T. C., Hutten, S. J., Green, A. & Soto, C., 6 Mar 2019, In: Movement Disorders.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Diagnostic value of surrogate CSF biomarkers for Creutzfeldt–Jakob disease in the era of RT-QuIC
Abu-rumeileh, S., Baiardi, S., Polischi, B., Mammana, A., Franceschini, A., Green, A., Capellari, S. & Parchi, P., 20 Sep 2019, In: Journal of Neurology.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Projects
-
Establishing alpha-synuclein RT-QuIC assay as a diagnostic technique in REM Sleep Behaviour Disorder
Riha, R. & Green, A.
1/09/18 → 31/05/22
Project: Research
-
Assessing and defining pre-clinical vCJD infectivity using transmission and protein aggregation models
Barria Matus, M., Green, A., Knight, R., Molesworth, A., Ritchie, D. & Smith, C.
UK central government bodies/local authorities, health and hospital authorities
1/11/17 → 31/10/21
Project: Research
-
National CJD Research And Surveillance Unit Core Grant
Green, A., Knight, R., Molesworth, A., Pal, S., Smith, C. & Will, B.
UK central government bodies/local authorities, health and hospital authorities
1/04/17 → 31/03/22
Project: Research
-
Multi-center evaluation of improved RT-QuIC diagnostic assays for Creutzfeldt-Jakob and other human prion diseases
31/01/16 → 30/09/19
Project: Research
Press / Media
-
Dr Alison Green works on test that can detect Parkinson's disease and Lewy body dementia
6/02/17
1 item of Media coverage
Press/Media: Research
-
Parkinson’s study could pave way for early detection test, says Dr Alison Green
29/08/16
37 items of Media coverage
Press/Media: Research
-
Dr Alison Green (Clinical Sciences) working on a modified version of a capable of detecting Parkinson's disease and Lewy body dementia
24/02/17
1 item of Media coverage
Press/Media: Research