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Collaborations and top research areas from the last five years
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New Mechanistic Insights into Targeted Protein Degradation Using Raman-Active Theranostic Hydrophobic Tags
Steven, C. F., Ravindra, M. P., Lee, M., Makar, A., Stubbs, C., Lochhead, P. A., Winlow, P., Barratt, D., Kriegsheim, A. V., Davey, P. R. J., Brunton, V. G. & Hulme, A. N., 28 Nov 2025, (E-pub ahead of print) In: European Journal of Medicinal Chemistry. p. 118413Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Stapline: Development of a Force Field Library for Stapled Peptide Residues
Notari, E., Bluntzer, M., Michel, J. & Hulme, A. N., 22 Sept 2025, (Submitted) (ChemRxiv).Research output: Working paper › Preprint
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Heritage Science Applications of Ambient Mass Spectrometry
Vettorazzo, C., Sandström, E., Mackay, C. L., Troalen, L. & Hulme, A. N., 26 Mar 2025, (E-pub ahead of print) In: Analytical methods. 17, 17, p. 3357-3369Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Optimization of Cyclophilin B-Targeted Tri-vector Inhibitors for Novel MASH Treatments
Kouridaki, M.-E., Gillespie, J., Robinson, J., Mathie, T., Bain, L., Mcarthur, D., Morrison, A., Greenslade, D. B., Papadourakis, M., Maj, K., Cameron, K., Turner, D., Webster, S. P., Wear, M. A., Doughty-Shenton, D., Hulme, A. N. & Michel, J., 12 Mar 2025, (E-pub ahead of print) In: Journal of Medicinal Chemistry.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Raman active diyne-girder conformationally constrained p53 stapled peptides bind to MDM2 for visualisation without fluorophores
Morgan, D. C., Mcdougall, L., Knuhtsen, A., Buetow, L., Steven, C. F., Shepperson, O. A., Huang, D. T., Hulme, A. N. & Jamieson, A. G., 15 Jan 2025, (E-pub ahead of print) In: RSC Chemical Biology.Research output: Contribution to journal › Article › peer-review
Open AccessFile
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PV286 Development of Cyclophilin B-selective Inhibitors for MASH treatments
Michel, J. (Principal Investigator), Doughty Shenton, D. (Co-investigator) & Hulme, A. (Co-investigator)
Engineering and Physical Sciences Research Council
1/10/25 → 30/06/26
Project: Research
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Good Vibrations: Visualising life with multiphoton/coherent Raman scattering microscopy
Hulme, A. (Principal Investigator), Calder, E. (Co-investigator), Campbell, C. (Co-investigator), Degiacomi, M. (Co-investigator), Ferenbach, D. (Co-investigator), Hay, D. (Co-investigator), Horrocks, M. (Co-investigator), Kunath, T. (Co-investigator), Lee, M. (Co-investigator), Lowell, S. (Co-investigator), Vermeren, M. (Co-investigator) & Williams, A. (Co-investigator)
Biotechnology and Biological Sciences Research Council
1/08/25 → 31/07/26
Project: Research
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Stimulated Raman Scattering to track ASO and nucleotide drug delivery into cells and tissues
Hulme, A. (Principal Investigator)
1/05/23 → 31/10/26
Project: Research
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Microwave-Assisted Extraction and Analysis of Natural Dyes in Historical Chinese Textiles by UHPLC-PDA with Fastness Testing
Hulme, A. (Principal Investigator)
The Carnegie Trust for the Universities of Scotland
2/06/25 → 24/08/25
Project: Research
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A Survey of Barriers to Combining Pregnancy and Breastfeeding and an Academic Career in the Physical Sciences
Hulme, A. (Principal Investigator)
14/11/22 → 15/04/24
Project: Research
Datasets
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New methods for the synthesis of spirocyclic cephalosporin analogues
Zhao, A. (Creator), Hulme, A. (Creator) & Horsfall, L. (Creator), Edinburgh DataShare, 1 Oct 2021
DOI: 10.7488/ds/3144
Dataset
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A catch-and-release approach to selective modification of accessible tyrosine residues
Allan, C. (Creator), Kosar, M. (Creator), Burr, C. (Creator), Mackay, L. (Creator), Duncan, R. (Creator) & Hulme, A. (Creator), Edinburgh DataShare, 27 Sept 2018
DOI: 10.7488/ds/2445, https://doi.org/10.1002/cbic.201800532
Dataset
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Historical textile dye analysis using DESI-MS
Mackay, L. (Creator), Sandström, E. (Creator), Vettorazzo, C. (Creator), Troalen, L. (Creator) & Hulme, A. (Creator), Edinburgh DataShare, 1 May 2023
DOI: 10.7488/ds/3847, https://doi.org/10.3390/heritage6050212
Dataset
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Chloromethyl-triazole: A new motif for site-selective pseudo-acylation of proteins
Brewster, R. (Creator), Gavins, G. C. (Creator), Günthardt, B. (Creator), Farr, S. (Creator), Webb, K. M. (Creator), Voigt, P. (Creator) & Hulme, A. (Creator), Edinburgh DataShare, 16 Sept 2016
DOI: 10.7488/ds/1484
Dataset
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Development and Application of Desorption Electrospray Ionization Mass Spectrometry for Historical Dye Analysis
Hulme, A. (Creator), Sandström, E. (Creator), Vettorazzo, C. (Creator), Mackay, L. (Creator) & Troalen, L. (Creator), Edinburgh DataShare, 1 Mar 2023
DOI: 10.7488/ds/3816
Dataset
Press/Media
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A revolution in how we do chemistry: Best ideas of the century
19/01/26
1 Media contribution
Press/Media: Research