Andrew McIntosh

Article

Genetic stratification of depression by neuroticism: revisiting a diagnostic tradition

23andMe Research Team, 2 Oct 2019, (E-pub ahead of print) In: Psychological Medicine. p. 1-10 10 p.

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Genetic stratification of depression in UK Biobank

Howard, D. M., Folkersen, L., Coleman, J. R. I., Adams, M. J., Glanville, K., Werge, T., Hagenaars, S. P., Han, B., Porteous, D., Campbell, A., Clarke, T., Breen, G., Sullivan, P. F., Wray, N. R., Lewis, C. M. & Mcintosh, A. M., 24 May 2020, In: Translational Psychiatry. 10, 1

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Genetic variants in the ErbB4 gene are associated with white matter integrity

Zuliani, R., Moorhead, T. W. J., Bastin, M. E., Johnstone, E. C., Lawrie, S. M., Brambilla, P., O'Donovan, M. C., Owen, M. J., Hall, J. & McIntosh, A. M., 2011, In: Psychiatry Research. 191, 2, p. 133-7 5 p.

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Genetic variation in CNTNAP2 alters brain function during linguistic processing in healthy individuals

Whalley, H. C., O'Connell, G., Sussmann, J. E., Peel, A., Stanfield, A. C., Hayiou-Thomas, M. E., Johnstone, E. C., Lawrie, S. M., McIntosh, A. M. & Hall, J., 2011, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 156B, 8, p. 941-8 8 p.

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Genetic variation in Hyperpolarization-activated cyclic nucleotide-gated channels and its relationship with neuroticism, cognition and risk of depression

McIntosh, A. M., Simen, A. A., Evans, K. L., Hall, J., MacIntyre, D. J., Blackwood, D., Morris, A., Smith, B. H., Dominiczak, A., Porteous, D., Deary, I. & Thomson, P. A., 2012, In: Frontiers in genetics. 3, p. 116

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Genetic variation in the DAOA (G72) gene modulates hippocampal function in subjects at high risk of schizophrenia

Hall, J., Whalley, H., Moorhead, T. W. J., Baig, B. J., McIntosh, A. M., Job, D. E., Owens, D. G. C., Lawrie, S. M. & Johnstone, E. C., 1 Sep 2008, In: Biological Psychiatry. 64, 5, p. 428-433 6 p.

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Genetic variation in the G72 (DAOA) gene affects temporal lobe and amygdala structure in subjects affected by bipolar disorder

Zuliani, R., Moorhead, B., Job, D., McKirdy, J., Sussmann, J. E. D., Johnstone, E. C., Lawrie, S. M., Brambilla, P., Hall, J. & McIntosh, A. M., Sep 2009, In: Bipolar Disorders. 11, 6, p. 621-627 7 p.

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Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income

Hill, W. D., Davies, N. M., Ritchie, S. J., Skene, N. G., Bryois, J., Bell, S., Di Angelantonio, E., Roberts, D. J., Xueyi, S., Davies, G., Liewald, D. C. M., Porteous, D. J., Hayward, C., Butterworth, A. S., Mcintosh, A. M., Gale, C. R. & Deary, I. J., 16 Dec 2019, In: Nature Communications. 10, 1, 5741.

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Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci

Smith, D. J., Escott-Price, V., Davies, G., Bailey, M. E. S., Colodro-Conde, L., Ward, J., Vedernikov, A., Marioni, R., Cullen, B., Lyall, D., Hagenaars, S. P., Liewald, D. C. M., Luciano, M., Gale, C. R., Ritchie, S. J., Hayward, C., Nicholl, B., Bulik-Sullivan, B., Adams, M., Couvy-Duchesne, B. & 12 others, Graham, N., Mackay, D., Evans, J., Smith, B. H., Porteous, D. J., Medland, S. E., Martin, N. G., Holmans, P., McIntosh, A. M., Pell, J. P., Deary, I. J. & O'Donovan, M. C., 30 Jun 2016, In: Molecular Psychiatry. 21, 6, p. 749-757 9 p.

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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

eQTLGen Consortium, 23andMe Research Team, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S-A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J. & 33 others, Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T-K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Escott-Price, V., Kiadeh, F. H. F., Finucane, H. K., Forstner, A. J., Frank, J., Hall, L. S., MacIntyre, D. J., Thomson, P. A., Hayward, C., McIntosh, A. M. & Porteous, D. J., May 2018, In: Nature Genetics. 50, 5, p. 668-681 14 p.

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Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Multicenter Genetic Studies of Schizophrenia Consortium, Ripke, S., O'Dushlaine, C., Chambert, K., Moran, J. L., Kähler, A. K., Akterin, S., Bergen, S. E., Collins, A. L., Crowley, J. J., Fromer, M., Kim, Y., Lee, S. H., Magnusson, P. K. E., Sanchez, N., Stahl, E. A., Williams, S., Wray, N. R., Xia, K., Bettella, F. & 31 others, Borglum, A. D., Bulik-Sullivan, B. K., Cormican, P., Craddock, N., de Leeuw, C., Durmishi, N., Gill, M., Golimbet, V., Hamshere, M. L., Holmans, P., Hougaard, D. M., Kendler, K. S., Lin, K., Morris, D. W., Mors, O., Mortensen, P. B., Neale, B. M., O'Neill, F. A., Owen, M. J., Milovancevic, M. P., Posthuma, D., Powell, J., Richards, A. L., Riley, B. P., Ruderfer, D., Rujescu, D., Sigurdsson, E., Silagadze, T., Hall, J., Lawrie, S. & McIntosh, A., Oct 2013, In: Nature Genetics. 45, 10, p. 1150-9 10 p.

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Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

CONVERGE Consortium, CARDIoGRAM Consortium, GERAD1 Consortium, Power, R. A., Tansey, K. E., Buttenschøn, H. N., Cohen-Woods, S., Bigdeli, T., Hall, L. S., Kutalik, Z., Lee, S. H., Ripke, S., Steinberg, S., Teumer, A., Viktorin, A., Wray, N. R., Arolt, V., Baune, B. T., Boomsma, D. I., Børglum, A. D., Byrne, E. M., Castelao, E. & 31 others, Craddock, N., Craig, I. W., Dannlowski, U., Deary, I. J., Degenhardt, F., Forstner, A. J., Gordon, S. D., Grabe, H. J., Grove, J., Hamilton, S. P., Hayward, C., Heath, A. C., Hocking, L. J., Homuth, G., Hottenga, J. J., Kloiber, S., Krogh, J., Landén, M., Lang, M., Levinson, D. F., Lichtenstein, P., Lucae, S., MacIntyre, D. J., Madden, P., Magnusson, P. K. E., Martin, N. G., McIntosh, A. M., Middeldorp, C. M., Milaneschi, Y., Porteous, D. J. & Thomson, P., 15 Feb 2017, In: Biological Psychiatry. 81, 4

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Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

Mccartney, D. L., Min, J. L., Richmond, R. C., Lu, A. T., Sobczyk, M. K., Davies, G., Broer, L., Guo, X., Jeong, A., Jung, J., Kasela, S., Katrinli, S., Kuo, P., Matias-garcia, P. R., Mishra, P. P., Nygaard, M., Palviainen, T., Patki, A., Raffield, L. M., Ratliff, S. M. & 89 others, Richardson, T. G., Robinson, O., Soerensen, M., Sun, D., Tsai, P., Van Der Zee, M. D., Walker, R. M., Wang, X., Wang, Y., Xia, R., Xu, Z., Yao, J., Zhao, W., Correa, A., Boerwinkle, E., Dugué, P., Durda, P., Elliott, H. R., Gieger, C., De Geus, E. J. C., Harris, S. E., Hemani, G., Imboden, M., Kähönen, M., Kardia, S. L. R., Kresovich, J. K., Li, S., Lunetta, K. L., Mangino, M., Mason, D., Mcintosh, A. M., Mengel-from, J., Moore, A. Z., Murabito, J. M., Ollikainen, M., Pankow, J. S., Pedersen, N. L., Peters, A., Polidoro, S., Porteous, D. J., Raitakari, O., Rich, S. S., Sandler, D. P., Sillanpää, E., Smith, A. K., Southey, M. C., Strauch, K., Tiwari, H., Tanaka, T., Tillin, T., Uitterlinden, A. G., Van Den Berg, D. J., Van Dongen, J., Wilson, J. G., Wright, J., Yet, I., Arnett, D., Bandinelli, S., Bell, J. T., Binder, A. M., Boomsma, D. I., Chen, W., Christensen, K., Conneely, K. N., Elliott, P., Ferrucci, L., Fornage, M., Hägg, S., Hayward, C., Irvin, M., Kaprio, J., Lawlor, D. A., Lehtimäki, T., Lohoff, F. W., Milani, L., Milne, R. L., Probst-hensch, N., Reiner, A. P., Ritz, B., Rotter, J. I., Smith, J. A., Taylor, J. A., Van Meurs, J. B. J., Vineis, P., Waldenberger, M., Deary, I. J., Relton, C. L., Horvath, S. & Marioni, R. E., 29 Jun 2021, In: Genome Biology. 22, 1

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Genome-wide association study identifies 30 loci associated with bipolar disorder

Stahl, E. A., Breen, G., Forstner, A. J., Mcquillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R. I., Gaspar, H. A., De Leeuw, C. A., Steinberg, S., Pavlides, J. M. W., Trzaskowski, M., Byrne, E. M., Pers, T. H., Holmans, P. A., Richards, A. L., Abbott, L., Agerbo, E. & 257 others, Akil, H., Albani, D., Alliey-rodriguez, N., Als, T. D., Anjorin, A., Antilla, V., Awasthi, S., Badner, J. A., Bækvad-hansen, M., Barchas, J. D., Bass, N., Bauer, M., Belliveau, R., Bergen, S. E., Pedersen, C. B., Bøen, E., Boks, M. P., Boocock, J., Budde, M., Bunney, W., Burmeister, M., Bybjerg-grauholm, J., Byerley, W., Casas, M., Cerrato, F., Cervantes, P., Chambert, K., Charney, A. W., Chen, D., Churchhouse, C., Clarke, T., Coryell, W., Craig, D. W., Cruceanu, C., Curtis, D., Czerski, P. M., Dale, A. M., De Jong, S., Degenhardt, F., Del-favero, J., Depaulo, J. R., Djurovic, S., Dobbyn, A. L., Dumont, A., Elvsåshagen, T., Escott-price, V., Fan, C. C., Fischer, S. B., Flickinger, M., Foroud, T. M., Forty, L., Frank, J., Fraser, C., Freimer, N. B., Frisén, L., Gade, K., Gage, D., Garnham, J., Giambartolomei, C., Pedersen, M. G., Goldstein, J., Gordon, S. D., Gordon-smith, K., Green, E. K., Green, M. J., Greenwood, T. A., Grove, J., Guan, W., Guzman-parra, J., Hamshere, M. L., Hautzinger, M., Heilbronner, U., Herms, S., Hipolito, M., Hoffmann, P., Holland, D., Huckins, L., Jamain, S., Johnson, J. S., Juréus, A., Kandaswamy, R., Karlsson, R., Kennedy, J. L., Kittel-schneider, S., Knowles, J. A., Kogevinas, M., Koller, A. C., Kupka, R., Lavebratt, C., Lawrence, J., Lawson, W. B., Leber, M., Lee, P. H., Levy, S. E., Li, J. Z., Liu, C., Lucae, S., Maaser, A., Macintyre, D. J., Mahon, P. B., Maier, W., Martinsson, L., Mccarroll, S., Mcguffin, P., Mcinnis, M. G., Mckay, J. D., Medeiros, H., Medland, S. E., Meng, F., Milani, L., Montgomery, G. W., Morris, D. W., Mühleisen, T. W., Mullins, N., Nguyen, H., Nievergelt, C. M., Adolfsson, A. N., Nwulia, E. A., O’donovan, C., Loohuis, L. M. O., Ori, A. P. S., Oruc, L., Ösby, U., Perlis, R. H., Perry, A., Pfennig, A., Potash, J. B., Purcell, S. M., Regeer, E. J., Reif, A., Reinbold, C. S., Rice, J. P., Rivas, F., Rivera, M., Roussos, P., Ruderfer, D. M., Ryu, E., Sánchez-mora, C., Schatzberg, A. F., Scheftner, W. A., Schork, N. J., Shannon Weickert, C., Shehktman, T., Shilling, P. D., Sigurdsson, E., Slaney, C., Smeland, O. B., Sobell, J. L., Søholm Hansen, C., Spijker, A. T., St Clair, D., Steffens, M., Strauss, J. S., Streit, F., Strohmaier, J., Szelinger, S., Thompson, R. C., Thorgeirsson, T. E., Treutlein, J., Vedder, H., Wang, W., Watson, S. J., Weickert, T. W., Witt, S. H., Xi, S., Xu, W., Young, A. H., Zandi, P., Zhang, P., Zöllner, S., Adolfsson, R., Agartz, I., Alda, M., Backlund, L., Baune, B. T., Bellivier, F., Berrettini, W. H., Biernacka, J. M., Blackwood, D. H. R., Boehnke, M., Børglum, A. D., Corvin, A., Craddock, N., Daly, M. J., Dannlowski, U., Esko, T., Etain, B., Frye, M., Fullerton, J. M., Gershon, E. S., Gill, M., Goes, F., Grigoroiu-serbanescu, M., Hauser, J., Hougaard, D. M., Hultman, C. M., Jones, I., Jones, L. A., Kahn, R. S., Kirov, G., Landén, M., Leboyer, M., Lewis, C. M., Li, Q. S., Lissowska, J., Martin, N. G., Mayoral, F., Mcelroy, S. L., Mcintosh, A. M., Mcmahon, F. J., Melle, I., Metspalu, A., Mitchell, P. B., Morken, G., Mors, O., Mortensen, P. B., Müller-myhsok, B., Myers, R. M., Neale, B. M., Nimgaonkar, V., Nordentoft, M., Nöthen, M. M., O’donovan, M. C., Oedegaard, K. J., Owen, M. J., Paciga, S. A., Pato, C., Pato, M. T., Posthuma, D., Ramos-quiroga, J. A., Ribasés, M., Rietschel, M., Rouleau, G. A., Schalling, M., Schofield, P. R., Schulze, T. G., Serretti, A., Smoller, J. W., Stefansson, H., Stefansson, K., Stordal, E., Sullivan, P. F., Turecki, G., Vaaler, A. E., Vieta, E., Vincent, J. B., Werge, T., Nurnberger, J. I., Wray, N. R., Di Florio, A., Edenberg, H. J., Cichon, S., Ophoff, R. A., Scott, L. J., Andreassen, O. A., Kelsoe, J. & Sklar, P., 1 May 2019, In: Nature Genetics. 51, 5, p. 793-803

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Genome-wide association study identifies five new schizophrenia loci

Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium, Ripke, S., Sanders, A. R., Kendler, K. S., Levinson, D. F., Sklar, P., Holmans, P. A., Lin, D-Y., Duan, J., Ophoff, R. A., Andreassen, O. A., Scolnick, E., Cichon, S., St Clair, D., Corvin, A., Gurling, H., Werge, T., Rujescu, D., Blackwood, D. H. R., Pato, C. N. & 31 others, Malhotra, A. K., Purcell, S., Dudbridge, F., Neale, B. M., Rossin, L., Visscher, P. M., Posthuma, D., Ruderfer, D. M., Fanous, A., Stefansson, H., Steinberg, S., Mowry, B. J., Golimbet, V., De Hert, M., Jönsson, E. G., Bitter, I., Pietiläinen, O. P. H., Collier, D. A., Tosato, S., Agartz, I., Albus, M., Alexander, M., Amdur, R. L., Amin, F., Bass, N., Bergen, S. E., Black, D. W., Hansen, T., Maclean, A. W., McGhee, K. A. & McIntosh, A., 2011, In: Nature Genetics. 43, 10, p. 969-76 8 p.

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Genome-wide association study meta-analysis of the Alcohol Use Disorders Identification Test (AUDIT) in two population-based cohorts (N=141,932)

Sanchez-Roige, S., Palmer, A. A., Fontanillas, P., Elson, S. L., Research Team, T. ., of the Psychiatric Genomics Consortium, S. U. D. W. G., Adams, M., Howard, D., Edenberg, H. J., Davies, G., Crist, R. C., Deary, I., McIntosh, A. & Clarke, T., 19 Oct 2018, (E-pub ahead of print) In: American Journal of Psychiatry.

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Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)

Clarke, T-K., Adams, M. J., Davies, G., Howard, D. M., Hall, L. S., Padmanabhan, S., Murray, A. D., Smith, B. H., Campbell, A., Hayward, C., Porteous, D. J., Deary, I. J. & McIntosh, A. M., 31 Oct 2017, In: Molecular Psychiatry. 22, 10, p. 1376-1384 9 p.

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Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP

Wigmore, E., Hafferty, J., Hall, L., Howard, D. M., Clarke, T-K., Fabbri, C., Lewis, C. M., Uher, R., Navrady, L., Adams, M. J., Zeng, Y., Campbell, A., Gibson, J., Thomson, P., Hayward, C., Smith, B. H., Hocking, L. J., Padmanabhan, S., Deary, I., Porteous, D. & 4 others, Mors, O., Mattheisen, M., Nicodemus, K. & McIntosh, A., 31 Jan 2019, In: Pharmacogenomics Journal.

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Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

Psychiat Genomics Consortium, Witt, S. H., Streit, F., Jungkunz, M., Frank, J., Awasthi, S., Reinbold, C. S., Treutlein, J., Degenhardt, F., Forstner, A. J., Heilmann-Heimbach, S., Dietl, L., Schwarze, C. E., Schendel, D., Strohmaier, J., Abdellaoui, A., Adolfsson, R., Air, T. M., Akil, H., Alda, M. & 31 others, Alliey-Rodriguez, N., Andreassen, O. A., Babadjanova, G., Bass, N. J., Bauer, M., Baune, B. T., Bellivier, F., Bergen, S., Bethell, A., Biernacka, J. M., Blackwood, D. H. R., Boks, M. P., Boomsma, D. I., Borglum, A. D., Borrmann-Hassenbach, M., Brennan, P., Budde, M., Buttenschon, H. N., Byrne, E. M., Cervantes, P., Clarke, T-K., Craddock, N., Cruceanu, C., Curtis, D., Czerski, P. M., Dannlowski, U., Davis, T., de Geus, E. J. C., Di Florio, A., Djurovic, S. & McIntosh, A. M., 20 Jun 2017, In: Translational Psychiatry. 7, 9 p., 1155.

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Genome-Wide Association Study of Circadian Rhythmicity in 71,500 UK Biobank Participants and Polygenic Association with Mood Instability

Ferguson, A., Lyall, L. M., Ward, J., Strawbridge, R. J., Cullen, B., Graham, N., Niedzwiedz, C. L., Johnston, K. J. A., MacKay, D., Biello, S. M., Pell, J. P., Cavanagh, J., McIntosh, A. M., Doherty, A., Bailey, M. E. S., Lyall, D. M., Wyse, C. A. & Smith, D. J., Sep 2018, In: EBioMedicine. 35

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Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151)

Davies, G., Marioni, R. E., Liewald, D. C., Hill, W. D., Hagenaars, S. P., Harris, S. E., Ritchie, S. J., Luciano, M., Fawns-Ritchie, C., Lyall, D., Cullen, B., Cox, S. R., Hayward, C., Porteous, D. J., Evans, J., Mcintosh, A. M., Gallacher, J., Craddock, N., Pell, J. P., Smith, D. J. & 2 others, Gale, C. R. & Deary, I. J., 30 Jun 2016, In: Molecular Psychiatry. 21, 6, p. 758-767 10 p.

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Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

Howard, D. M., Adams, M. J., Shirali, M., Clarke, T-K., Marioni, R. E., Davies, G., Coleman, J. R. I., Alloza, C., Shen, X., Barbu, M. C., Wigmore, E. M., Gibson, J., 23andMe Research Team, Hagenaars, S. P., Lewis, C. M., Ward, J., Smith, D. J., Sullivan, P. F., Haley, C. S., Breen, G. & 2 others, Deary, I. J. & McIntosh, A. M., 16 Apr 2018, In: Nature Communications. 9, 1, p. 1-10 10 p., 1470.

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Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank

23andMe Research Team, 28 Aug 2019, In: Communications biology. 2, p. 321

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Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

HUNT All-In Psychiatry, Mullins, N., Forstner, A. J., O'Connell, K. S., Coombes, B., Coleman, J. R. I., Qiao, Z., Als, T. D., Bigdeli, T. B., Børte, S., Bryois, J., Charney, A. W., Drange, O. K., Gandal, M. J., Hagenaars, S. P., Ikeda, M., Kamitaki, N., Kim, M., Krebs, K., Panagiotaropoulou, G. & 31 others, Schilder, B. M., Sloofman, L. G., Steinberg, S., Trubetskoy, V., Winsvold, B. S., Won, H-H., Abramova, L., Adorjan, K., Agerbo, E., Al Eissa, M., Albani, D., Alliey-Rodriguez, N., Anjorin, A., Antilla, V., Antoniou, A., Awasthi, S., Baek, J. H., Bækvad-Hansen, M., Bass, N., Clarke, T-K., Kennedy, J. L., MacIntyre, D. J., Morris, D. W., Smith, D. J., Xu, W., Young, H., Zhou, H., Blackwood, D. H. R., Martin, N. G., McIntosh, A. M. & Sullivan, P. F., 17 May 2021, (E-pub ahead of print) In: Nature Genetics.

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Genome-wide association study of multisite chronic pain in UK biobank

Johnston, K. J. A., Adams, M. J., Nicholl, B. I., Ward, J., Strawbridge, R. J., Ferguson, A., McIntosh, A. M., Bailey, M. E. S. & Smith, D. J., 1 Jun 2019, In: PLoS Genetics. 15, 6, e1008164.

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Genome-wide association study of suicide death and polygenic prediction of clinical antecedents.

McIntosh, A., 1 Oct 2020, In: American Journal of Psychiatry.

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Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland

Arnau Soler, A., MacDonald-Dunlop, E., Adams, M. J., Clarke, T-K., MacIntyre, D., Milburn, K., Navrady, L., Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Hayward, C., McIntosh, A. & Thomson, P., 4 Feb 2019, In: Translational Psychiatry. 9, 1, 13 p., 14.

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Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Coleman, J. R. I., Adams, M. J. & McIntosh, A., 23 Jan 2020, In: Molecular Psychiatry.

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Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

Howard, D. M., Hall, L., Hafferty, J., Zeng, Y., Adams, M. J., Clarke, T-K., Porteous, D., Nagy, R., Hayward, C., Smith, B. H., Murray, A., Ryan, N., Evans, K., Haley, C., Deary, I., Thomson, P. & McIntosh, A., 30 Nov 2017, (E-pub ahead of print) In: Translational Psychiatry. 7, 1263.

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Genome-wide interaction study with major depression identifies novel variants associated with cognitive function

Thalamuthu, A., Mills, N. T., Berger, K., Minnerup, H., Grotegerd, D., Dannlowski, U., Meinert, S., Opel, N., Repple, J., Gruber, M., Nenadić, I., Stein, F., Brosch, K., Meller, T., Pfarr, J-K., Forstner, A. J., Hoffmann, P., Nöthen, M. M., Witt, S., Rietschel, M. & 13 others, Kircher, T., Adams, M., McIntosh, A. M., Porteous, D. J., Deary, I. J., Hayward, C., Campbell, A., Grabe, H. J., Teumer, A., Homuth, G., van der Auwera-Palitschka, S., Oliver Schubert, K. & Baune, B. T., 15 Nov 2021, (E-pub ahead of print) In: Molecular Psychiatry.

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Genome-wide meta-analyses of stratified depression in Generation Scotland and UK Biobank

Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Porteous, D., Deary, I., Thomson, P., Haley, C. & McIntosh, A., 10 Jan 2018, (E-pub ahead of print) In: Translational Psychiatry. 8, 9.

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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

Howard, D. M., Adams, M. J., Clarke, T-K., Hafferty, J. D., Gibson, J., Shirali, M., Coleman, J. R. I., Hagenaars, S. P., Ward, J., Wigmore, E. M., Alloza, C., Shen, X., Barbu, M. C., Xu, E. Y., Whalley, H. C., Marioni, R. E., Porteous, D. J., Davies, G., Deary, I. J., Hemani, G. & 20 others, Berger, K., Teismann, H., Rawal, R., Arolt, V., Baune, B. T., Dannlowski, U., Domschke, K., Tian, C., Hinds, D. A., 23andMe Research Team, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Trzaskowski, M., Byrne, E. M., Ripke, S., Smith, D. J., Sullivan, P. F., Wray, N. R., Breen, G., Lewis, C. M. & McIntosh, A. M., 31 Mar 2019, In: Nature Neuroscience. 22, 3, p. 343–352 10 p.

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Genome-wide methylation data improves dissection of the effect of smoking on body mass index

Amador, C., Zeng, Y., Barber, M., Walker, R., Campbell, A., McIntosh, A. M., Evans, K. L., Porteous, D. J., Hayward, C., Wilson, J. F., Navarro, P. & Haley, C. S., 9 Sep 2021, (E-pub ahead of print) In: PLoS Genetics.

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Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with Major Depressive Disorder

Zeng, Y., Navarro, P., Shirali, M., Howard, D., Adams, M., Hall, L., Clarke, T-K., Thomson, P., Smith, B. H., Murray, A., Padmanabhan, S., Hayward, C., Boutin, T., MacIntyre, D., Lewis, C. M., Wray, N. R., Mehta, D., Penninx, B., Milaneschi, Y., Baune, B. T. & 19 others, Air, T., Hottenga, J-J., Mbarek, H., Castelao, E., Pistis, G., Schulze, T. G., Streit, F., Forstner, A. J., Byrne, E. M., Martin, N. G., Breen, G., Müller-Myhsok, B., Lucae, S., Kloiber, S., Domenici, E., Deary, I., Porteous, D., Haley, C. & McIntosh, A., 1 Sep 2017, In: Biological Psychiatry. 82, 5, p. 312-321

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Genomic analysis of family data reveals additional genetic effects on intelligence and personality

Hill, W. D., Arslan, R. C., Xia, C., Luciano, M., Amador, C., Navarro, P., Hayward, C., Nagy, R., Porteous, D. J., McIntosh, A. M., Deary, I. J., Haley, C. S. & Penke, L., 31 Dec 2018, In: Molecular Psychiatry. 23, 12, p. 2347–2362 16 p.

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Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

Min, J. L., Hemani, G., Hannon, E., Dekkers, K. F., Castillo-fernandez, J., Luijk, R., Carnero-montoro, E., Lawson, D. J., Burrows, K., Suderman, M., Bretherick, A. D., Richardson, T. G., Klughammer, J., Iotchkova, V., Sharp, G., Al Khleifat, A., Shatunov, A., Iacoangeli, A., Mcardle, W. L., Ho, K. M. & 135 others, Kumar, A., Söderhäll, C., Soriano-tárraga, C., Giralt-steinhauer, E., Kazmi, N., Mason, D., Mcrae, A. F., Corcoran, D. L., Sugden, K., Kasela, S., Cardona, A., Day, F. R., Cugliari, G., Viberti, C., Guarrera, S., Lerro, M., Gupta, R., Bollepalli, S., Mandaviya, P., Zeng, Y., Clarke, T., Walker, R. M., Schmoll, V., Czamara, D., Ruiz-arenas, C., Rezwan, F. I., Marioni, R. E., Lin, T., Awaloff, Y., Germain, M., Aïssi, D., Zwamborn, R., Van Eijk, K., Dekker, A., Van Dongen, J., Hottenga, J., Willemsen, G., Xu, C., Barturen, G., Català-moll, F., Kerick, M., Wang, C., Melton, P., Elliott, H. R., Shin, J., Bernard, M., Yet, I., Smart, M., Gorrie-stone, T., Shaw, C., Al Chalabi, A., Ring, S. M., Pershagen, G., Melén, E., Jiménez-conde, J., Roquer, J., Lawlor, D. A., Wright, J., Martin, N. G., Montgomery, G. W., Moffitt, T. E., Poulton, R., Esko, T., Milani, L., Metspalu, A., Perry, J. R. B., Ong, K. K., Wareham, N. J., Matullo, G., Sacerdote, C., Panico, S., Caspi, A., Arseneault, L., Gagnon, F., Ollikainen, M., Kaprio, J., Felix, J. F., Rivadeneira, F., Tiemeier, H., Van Ijzendoorn, M. H., Uitterlinden, A. G., Jaddoe, V. W. V., Haley, C., Mcintosh, A. M., Evans, K. L., Räikkönen, K., Lahti, J., Nohr, E. A., Sørensen, T. I. A., Hansen, T., Morgen, C. S., Binder, E. B., Lucae, S., Gonzalez, J. R., Bustamante, M., Sunyer, J., Holloway, J. W., Karmaus, W., Zhang, H., Deary, I. J., Wray, N. R., Starr, J. M., Beekman, M., Van Heemst, D., Slagboom, P. E., Morange, P., Trégouët, D., Veldink, J. H., Davies, G. E., De Geus, E. J. C., Boomsma, D. I., Vonk, J. M., Brunekreef, B., Koppelman, G. H., Alarcón-riquelme, M. E., Huang, R., Pennell, C. E., Van Meurs, J., Ikram, M. A., Hughes, A. D., Tillin, T., Chaturvedi, N., Pausova, Z., Paus, T., Spector, T. D., Kumari, M., Schalkwyk, L. C., Visscher, P. M., Davey Smith, G., Bock, C., Gaunt, T. R., Bell, J. T., Heijmans, B. T., Mill, J. & Relton, C. L., 6 Sep 2021, In: Nature Genetics. 53, 9, p. 1311-1321

Research output: Contribution to journal › Article › peer-review

Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits

Grotzinger, A., Rhemtulla, M., Vlaming, R. D., Ritchie, S. J., Mallard, T. T., Hill, W. D., Hill, F., Marioni, R., McIntosh, A., Deary, I., Koellinger, P. D., Harden, K. P., Nivard, M. G. & Tucker-Drob, E. M., May 2019, In: Nature Human Behaviour. 3, 5, p. 513-525

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Greater male than female variability in regional brain structure across the lifespan

ENIGMA Consortium, 12 Oct 2020, In: Human Brain Mapping.

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Open Access

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Grey matter changes can improve the prediction of schizophrenia in subjects at high risk

Job, D. E., Whalley, H. C., McIntosh, A. M., Owens, D. G. C., Johnstone, E. C. & Lawrie, S. M., 7 Dec 2006, In: BMC Medicine. 4, 4 p., 29.

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Grey matter correlates of early psychotic symptoms in adolescents at enhanced risk of psychosis: a voxel-based study

Spencer, M. D., Moorhead, T. W. J., McIntosh, A. M., Stanfield, A. C., Muir, W. J., Hoare, P., Owens, D. G. C., Lawrie, S. M. & Johnstone, E. C., 2007, In: NeuroImage. 35, 3, p. 1181-91 11 p.

Research output: Contribution to journal › Article › peer-review

Grey matter differences in bipolar disorder: a meta-analysis of voxel-based morphometry studies

Selvaraj, S., Arnone, D., Job, D., Stanfield, A., Farrow, T. F., Nugent, A. C., Scherk, H., Gruber, O., Chen, X., Sachdev, P. S., Dickstein, D. P., Malhi, G. S., Ha, T. H., Ha, K., Phillips, M. L. & McIntosh, A. M., Mar 2012, In: Bipolar Disorders. 14, 2, p. 135-145 11 p.

Research output: Contribution to journal › Article › peer-review

Hair glucocorticoids are associated with childhood adversity, depressive symptoms and reduced global and lobar grey matter in Generation Scotland

Green, C., Stolicyn, A., Harris, M. A., Shen, X., Romaniuk, L., Barbu, M. C., Hawkins, E. L., Wardlaw, J. M., Steele, J. D., Waiter, G. D., Sandu, A., Campbell, A., Porteous, D. J., Seckl, J. R., Lawrie, S. M., Reynolds, R. M., Cavanagh, J., Mcintosh, A. M. & Whalley, H. C., 12 Oct 2021, In: Translational Psychiatry. 11, 1

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Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank

Howard, D. M., Adams, M. J., Clarke, T., Wigmore, E. M., Zeng, Y., Hagenaars, S. P., Lyall, D. M., Thomson, P. A., Evans, K. L., Porteous, D. J., Nagy, R., Hayward, C., Haley, C. S., Smith, B. H., Murray, A. D., Batty, G. D., Deary, I. J. & Mcintosh, A. M., 10 Aug 2017, (E-pub ahead of print) In: Wellcome Open Research . 10 p., 261.

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Heritability of fractional anisotropy in human white matter: A comparison of Human Connectome Project and ENIGMA-DTI data

Kochunov, P., Jahanshad, N., Marcus, D., Winkler, A., Sprooten, E., Nichols, T. E., Wright, S. N., Hong, L. E., Patel, B., Behrens, T., Jbabdi, S., Andersson, J., Lenglet, C., Yacoub, E., Moeller, S., Auerbach, E., Ugurbil, K., Sotiropoulos, S. N., Brouwer, R. M., Landman, B. & 33 others, Lemaitre, H., den Braber, A., Zwiers, M. P., Ritchie, S., van Hulzen, K., Almasy, L., Curran, J., deZubicaray, G. I., Duggirala, R., Fox, P., Martin, N. G., McMahon, K. L., Mitchell, B., Olvera, R. L., Peterson, C., Starr, J., Sussmann, J., Wardlaw, J., Wright, M., Boomsma, D. I., Kahn, R., de Geus, E. J. C., Williamson, D. E., Hariri, A., van 't Ent, D., Bastin, M. E., McIntosh, A., Deary, I. J., Hulshoff Pol, H. E., Blangero, J., Thompson, P. M., Glahn, D. C. & Van Essen, D. C., 4 Mar 2015, In: NeuroImage. 111, p. 300-311 12 p.

Research output: Contribution to journal › Article › peer-review

Hippocampal and amygdala volumes in borderline personality disorder: A meta-analysis of magnetic resonance imaging studies

Hall, J., Olabi, B., Lawrie, S. M. & Mcintosh, A. M., Aug 2010, In: Personality and Mental Health. 4, 3, p. 172-179 8 p.

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Hippocampal function in schizophrenia and bipolar disorder

Hall, J., Lawrie, S. M., McIntosh, A. M., Johnstone, E. C., Romaniuk, L., Sussmann, J., Wan, H. I., McKirdy, J., Hall, J., Whalley, H. C. & Marwick, K., May 2010, In: Psychological Medicine. 40, 5, p. 761-770 10 p.

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How data science can advance mental health research

Russ, T. C., Woelbert, E., Davis, K. A. S., Hafferty, J. D., Ibrahim, Z., Inkster, B., John, A., Lee, W., Maxwell, M., Mcintosh, A. M. & Stewart, R., 10 Dec 2018, In: Nature Human Behaviour.

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Hypofrontality in subjects at high genetic risk of schizophrenia with depressive symptoms

Whalley, H. C., Mowatt, L., Stanfield, A. C., Hall, J., Johnstone, E. C., Lawrie, S. M. & McIntosh, A. M., 2008, In: Journal of Affective Disorders (JAD). 109, 1-2, p. 99-106 8 p.

Research output: Contribution to journal › Article › peer-review

Identification of common genetic risk variants for autism spectrum disorder

BUPGEN, 23AndMe Res Team, Psychiat Genomics Consortium, Maller, J., Martin, J., Martin, A., Moran, J., Nyegaard, M., Naerland, T., Palmer, D., Palotie, A., Bocker Perdersen, C., Giortz Pedersen, M., dPoterba, T., Buchhave Poulsen, J., St Poucain, B., Qvist, P., Rehnstrom, K., Reichenberg, A., Reichert, J. & 24 others, Robinson, E. B., Roeder, K., Roussos, P., Saemundsen, E., Sandin, S., Satterstrom, F. K., Smith, G. D., Stefansson, H., Steinberg, S., Stevens, C. R., Sullivan, P. F., Turley, P., Walters, G. B., Xu, X., Stefansson, K., Geschwind, D. H., Nordentoft, M., Hougaard, D. M., Werge, T., Mors, O., Mortensen, P. B., Neale, B. M., Daly, M. J. & Borglum, A. D., Mar 2019, In: Nature Genetics. 51, 3, p. 431-+ 16 p.

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Identification of common variants associated with human hippocampal and intracranial volumes

the Alzheimer's Disease Neuroimaging Initiative (ADNI), Stein, J. L., Medland, S. E., Vasquez, A. A., Hibar, D. P., Senstad, R. E., Winkler, A. M., Toro, R., Appel, K., Bartecek, R., Bergmann, O., Bernard, M., Brown, A. A., Cannon, D. M., Chakravarty, M. M., Christoforou, A., Domin, M., Grimm, O., Hollinshead, M., Holmes, A. J. & 31 others, Homuth, G., Hottenga, J-J., Langan, C., Lopez, L. M., Hansell, N. K., Hwang, K. S., Kim, S., Laje, G., Lee, P. H., Liu, X., Loth, E., Lourdusamy, A., Mattingsdal, M., Mohnke, S., Maniega, S. M., Nho, K., Nugent, A. C., Davies, G., Lawrie, S. M., Liewald, D. C., Royle, N. A., Smith, C., Valdés Hernández, M. C., Hall, J., Porteous, D. J., Starr, J. M., Sussmann, J., Bastin, M. E., Deary, I. J., McIntosh, A. M. & Wardlaw, J. M., 2012, In: Nature Genetics. 44, 5, p. 552-561 10 p.

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Andrew McIntosh

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