Andrew McIntosh

Search results

• Working paper

  The Common Genetic Architecture of Anxiety Disorders

  Purves, K. L., Coleman, J. R. I., Rayner, C., Hettema, J. M., Deckert, J., McIntosh, A. M., Nicodemus, K. K., Breen, G. & Eley, T. C., 1 Jan 2017, bioRxiv, at Cold Spring Harbor Laboratory.

  Research output: Working paper

  • Anxiety Disorders 100%
  • Anxiety 73%
  • Chromosomes, Human, Pair 9 20%
  • Phenotype 19%
  • Genome-Wide Association Study 16%
• Review article

  ENIGMA MDD: seven years of global neuroimaging studies of major depression through worldwide data sharing

  Schmaal, L., Pozzi, E., C. Ho, T., Van Velzen, L. S., Veer, I. M., Opel, N., Van Someren, E. J. W., Han, L. K. M., Aftanas, L., Aleman, A., Baune, B. T., Berger, K., Blanken, T. F., Capitão, L., Couvy-duchesne, B., R. Cullen, K., Dannlowski, U., Davey, C., Erwin-grabner, T., Evans, J. & 58 others, Frodl, T., Fu, C. H. Y., Godlewska, B., Gotlib, I. H., Goya-maldonado, R., Grabe, H. J., Groenewold, N. A., Grotegerd, D., Gruber, O., Gutman, B. A., Hall, G. B., Harrison, B. J., Hatton, S. N., Hermesdorf, M., Hickie, I. B., Hilland, E., Irungu, B., Jonassen, R., Kelly, S., Kircher, T., Klimes-dougan, B., Krug, A., Landrø, N. I., Lagopoulos, J., Leerssen, J., Li, M., Linden, D. E. J., Macmaster, F. P., M. Mcintosh, A., Mehler, D. M. A., Nenadić, I., Penninx, B. W. J. H., Portella, M. J., Reneman, L., Rentería, M. E., Sacchet, M. D., G. Sämann, P., Schrantee, A., Sim, K., Soares, J. C., Stein, D. J., Tozzi, L., Van Der Wee, N. J. A., Van Tol, M., Vermeiren, R., Vives-gilabert, Y., Walter, H., Walter, M., Whalley, H. C., Wittfeld, K., Whittle, S., Wright, M. J., Yang, T. T., Zarate, C., Thomopoulos, S. I., Jahanshad, N., Thompson, P. M. & Veltman, D. J., 29 May 2020, In: Translational Psychiatry. 10, 1

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

• Pharmacoepidemiology research: delivering evidence about drug safety and effectiveness in mental health

  Davis, K. A. S., Farooq, S., Hayes, J. F., John, A., Lee, W., Maccabe, J. H., Mcintosh, A., Osborn, D. P. J., Stewart, R. J. & Woelbert, E., 25 Nov 2019, (E-pub ahead of print) In: The Lancet Psychiatry.

  Research output: Contribution to journal › Review article › peer-review

• Rediscovering the value of families for psychiatric genetics research

  Glahn, D. C., Nimgaonkar, V. L., Raventós, H., Contreras, J., McIntosh, A. M., Thomson, P. A., Jablensky, A., McCarthy, N. S., Charlesworth, J. C., Blackburn, N. B., Peralta, J. M., Knowles, E. E. M., Mathias, S. R., Ament, S. A., McMahon, F. J., Gur, R. C., Bucan, M., Curran, J. E., Almasy, L., Gur, R. E. & 1 others, Blangero, J., 28 Jun 2018, (E-pub ahead of print) In: Molecular Psychiatry.

  Research output: Contribution to journal › Review article › peer-review

  • Genetic Research 100%
  • Pedigree 86%
  • Psychiatry 58%
  • Genome 53%
  • Psychotic Affective Disorders 28%

• Schizophrenia.

  Lawrie, S., McIntosh, A. & Nadeem, Z., 1 Jan 2005, In: Clinical evidence. 14, p. 1306-1330 25 p.

  Research output: Contribution to journal › Review article › peer-review

• Uncovering the genetic architecture of major depression

  McIntosh, A., Sullivan, P. F. & Lewis, C. M., 3 Apr 2019, (E-pub ahead of print) In: Neuron.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File
• Poster

  Machine learning can improve prediction of depression in Generation Scotland

  Bermingham, M., Munoz, D. U., Agakov, F., Campbell, A., Wigmore, E., Clarke, T-K., McIntosh, A., McKeigue, P., Porteous, D. & Nicodemus, K., 1 Sep 2015.

  Research output: Contribution to conference › Poster › peer-review

  Open Access

  File
• Paper

  Leveraging DNA methylation signatures in peripheral blood as predictors of impaired respiratory function and chronic obstructive pulmonary disease.

  Bermingham, M., Evans, K., McIntosh, A., Porteous, D., Deary, I., Hayward, C., Walker, R., Marioni, R., Morris, S., Rawlik, K., Zeng, Y., Campbell, A., Redmond, P., Sibley, H. & Adams, M. J., 12 Mar 2019.

  Research output: Contribution to conference › Paper › peer-review

  • DNA Methylation 100%
  • Chronic Obstructive Pulmonary Disease 90%
  • Epigenome 37%
  • Parturition 14%
  • Axon Guidance 12%

• Machine learning can improve prediction of lifetime major depressive disorder in the Generation Scotland: Scottish Family Health Study

  Bermingham, M., Porteous, D., MacIntyre, D., Clarke, T-K., Nicodemus, K., Munoz, D. U., Agakov, F., Campbell, A., Hayward, C., Wigmore, E., Gibson, J., Fernandez-Pujals, A. M., MacIntyre, D., McIntosh, A., Porteous, D. & Nicodemus, K., 11 May 2016.

  Research output: Contribution to conference › Paper › peer-review
• Other report

  MQ Data Science Report to MRC on building a National Infrastructure for Mental Health Data Science in the UK

  Beange, I., Iveson, M., Mai, H., McIntosh, A., Xenaki, C., Zhang, N., Smith, D. & Wölbert, E., 9 Sep 2019, Edinburgh: Edinburgh Medical School Publications. 12 p.

  Research output: Book/Report › Other report

  Open Access

  • Data Science 100%
  • Mental Health 56%
  • Referral and Consultation 39%
  • Organizations 30%
  • Directories 25%
• Other contribution

  Quarantine: infection prevention, but at what cost for mental health?

  Iveson, M. & McIntosh, A., 30 Mar 2020, The Mental Elf.

  Research output: Other contribution
• Meeting abstract

  Activation During Angry Face Processing Differentiates Bipolar Relatives with Mood Disorders from those without

  Sussmann, J., Whalley, H., Romaniuk, L., Stewart, T., Papmeyer, M., Sprooten, E., Lawrie, S. & McIntosh, A., 15 Apr 2012, In: Biological Psychiatry. 71, 8, p. 207S-207S 1 p.

  Research output: Contribution to journal › Meeting abstract

• A Neuregulin 1 variant associated with altered brain structure and function

  McIntosh, A. M., Apr 2008, In: European Psychiatry. 23, p. S18-S18 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Associations of Polygenic Risk for Major Psychiatric Disorder With Brain Structure in Depression and Application to Stratification

  Whalley, H., Harris, M., Shen, X., Gibson, J., Adams, M., Clarke, T., Lawrie, S. & McIntosh, A., 15 May 2019, In: Biological Psychiatry. 85, 10, p. S19-S20 2 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Brain Network Structural Covariance in Youth at High Familial Risk for Bipolar Disorder

  Heinze, K., McIntosh, A., Wood, S., Harris, M., Hawkins, E. & Sibley, H., Oct 2018, In: Early Intervention in Psychiatry. 12, p. 67-67 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• CLINICAL AND GENETIC RE-EVALUATION OF THE SCOTTISH DISCI TRANSLOCATION FAMILY

  Thomson, P., Duff, B., McCarthy, S., Ryan, N. M., Whalley, H. C., de la Bastide, M., Morris, S. W., McIntosh, A. M., Evans, K. L., Lawrie, S. M., Blackwood, D. H. R., McCombie, W. R. & Porteous, D. J., Oct 2017, In: European Neuropsychopharmacology. 27, p. S276-S277 2 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Cognitive Performance in Major Depressive Disorder in Generation Scotland: The Scottish Family Health Study (GS:SFHS)

  Meijsen, J., Campbell, A., McIntosh, A., Porteous, D., Deary, I., Marioni, R. & Nicodemus, K., 15 May 2017, In: Biological Psychiatry. 81, 10, p. S217-S217 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Endophenotypes for Depression and their Value in Gene Discovery

  McIntosh, A. M., Clarke, T., Hall, L. S., Fernandez, A. M. P. & Haley, C., 1 May 2015, In: Biological Psychiatry. 77, 9, 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• ENDOPHENOTYPES FOR SCHIZOPHRENIA AND BIPOLAR DISORDER DETERMINED USING BRAIN IMAGING

  McIntosh, A. M., Hall, J. & Lawrie, S. M., Mar 2009, In: Schizophrenia Bulletin. 35, p. 218-218 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Evidence of shared white matter disruption in bipolar disorder and sschizophrenia

  McIntosh, A. M., Sussmann, J., Lymer, G. K. S., Munoz-Maniega, S., Bastin, M., Hall, J., Lawrie, S., Johnstone, E., Clayden, J., Job, D. & Moorhead, T. W. J., Apr 2008, In: European Psychiatry. 23, p. S43-S43 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Fronto-Temporal Connectivity in Bipolar Disorder and Schizophrenia Related to Auditory Verbal Hallucinations

  Sprooten, E., Romaniuk, L., Giles, S., Job, D. E., Mukherjee, P., Whalley, H. C., Lawrie, S. M., Johnstone, E. C., van de Ven, V. G. & McIntosh, A. M., 15 Apr 2009, In: Biological Psychiatry. 65, 8, p. 131S-131S 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Functional Imaging of Emotional Memory in Individuals at High Familial Risk of Bipolar Disorder with and without Depression

  Whalley, H. C., Sussmann, J. E., Romaniuk, L., Hall, J., Lawrie, S. M. & McIntosh, A. M., 1 May 2013, In: Biological Psychiatry. 73, 9, p. 256S-256S 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Gene-By-Environment Analyses Reveal Obstetric Complications Interact with Genetics to Influence Psychopathology and Personality

  Gountouna, V-E., Hafferty, J., Campbell, A., Porteous, D., McIntosh, A. & Nicodemus, K., 15 May 2017, In: Biological Psychiatry. 81, 10, p. S368-S368 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Genetics and Neurobiology of Anxiety and Depression

  McIntosh, A., Whalley, H. C. & Lawrie, S. M., 28 Mar 2015, In: European Psychiatry. 30, 1 p.

  Research output: Contribution to journal › Meeting abstract

• Grey Matter Endophenotypes in Bipolar Disorder

  McIntosh, A. M., 15 Apr 2009, In: Biological Psychiatry. 65, 8, p. 94S-94S 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Imaging the Mechanisms Underlying Vulnerability to Bipolar Disorder

  McIntosh, A. M., 1 May 2010, In: Biological Psychiatry. 67, 9, p. 143S-143S 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Meta-analysis of magnetic resonance imaging studies of the corpus callosum in bipolar disorder

  Arnone, D., McIntosh, A. M., Chandra, P. & Ebmeier, K. P., Apr 2008, In: European Psychiatry. 23, p. S225-S225 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Meta-analysis of region of interest studies in unipolar depression and bipolar disorder

  Arnone, D., McIntosh, A. M., Ebmeier, K. P. & Anderson, I. M., Sep 2009, In: European Neuropsychopharmacology. 19, p. S375-S375 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Patterns of grey matter density partially separate schizophrenia and bipolar disorder

  McIntosh, A., Job, D., Moorhead, B., Harrison, L., Forrester, K., Lawrie, S. & Johnstone, E., 2004, In: Acta Psychiatrica Scandinavica. 110, p. 28-28 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Patterns of grey matter loss discriminate between schizophrenia and bipolar disorder

  McIntosh, AM., Job, D., Harrison, LK., Forrester, K., Moorhead, TW. & Johnstone, EC., 15 Feb 2004, In: Schizophrenia Research. 67, 1, p. 26-26 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Prediction of Mood Disorder in Those at Familial Risk using fMRI

  Whalley, H. C., Sussmann, J. E., Romaniuk, L., Stewart, T., Papmeyer, M., Sprooten, E., Lawrie, S. M. & McIntosh, A. M., 15 Apr 2012, In: Biological Psychiatry. 71, 8, p. 207S-207S 1 p.

  Research output: Contribution to journal › Meeting abstract

• SHARED GENETIC ARCHITECTURE BETWEEN COGNITION AND REGIONAL BRAIN VOLUME

  Wigmore, E., Clarke, T., Nicodemus, K. & McIntosh, A., Oct 2017, In: European Neuropsychopharmacology. 27, p. S306-S307 2 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Structural and Functional Brain Abnormalities in People at High Risk of Bipolar Disorder for Familial Reasons

  McIntosh, A. M., 1 May 2010, In: Biological Psychiatry. 67, 9, p. 15S-15S 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Structural and functional neuroimaging studies of schizophrenia and bipolar disorder

  Hall, J., Sussmann, J., Moorehead, W., Whalley, H., Johnstone, E. C., Lawrie, S. & McIntosh, A., 1 Apr 2008, In: Biological Psychiatry. 63, 7, p. 156S-156S 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Structural MRI in bipolar disorder: An international collaborative mega-analysis of individual patient data

  Hallahan, B., Newell, J., Soares, J. C., Brambilla, P., Strakowski, S. M., Fleck, D. E., Kieseppa, T., Altshuler, L. L., Fornito, A., Malhi, G. S., McIntosh, A. M., Yurgelun-Todd, D. A., LaBar, K. S., Densmore, M., MacQueen, G. M., Murray, R. M. & McDonald, C., Jun 2009, In: Bipolar Disorders. 11, p. 10-11 2 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Susceptibility Gene Variants for Schizophrenia and Bipolar Disorder Associated with Disrupted Functional and Structural Connectivity

  McIntosh, A. M., 15 Apr 2009, In: Biological Psychiatry. 65, 8, p. 14S-14S 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• The Relationship of Anterior Thalamic Radiation Integrity to Psychosis Risk Associated Neuregulin-1 Variants

  Sprooten, E., Lymer, G. K., Maniega, S. M., McKirdy, J., Clayden, J. D., Bastin, M. E., Porteous, D., Johnstone, E. C., Lawrie, S. M., Hall, J. & McIntosh, A. M., 15 Apr 2009, In: Biological Psychiatry. 65, 8, p. 202S-203S 2 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• WHITE MATTER DISRUPTION IN INDIVIDUALS WITH PSYCHOSIS AND THOSE AT HIGH FAMILIAL RISK DETERMIEND BY SPECIFIC GENETIC VARIANTS

  McIntosh, A. M., Sprooten, E., Zuliani, R., Sussmann, J., Hall, J. & Lawrie, S., Mar 2009, In: Schizophrenia Bulletin. 35, p. 209-209 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Literature review

  Associative learning and the genetics of schizophrenia

  Hall, J., Romaniuk, L., McIntosh, A. M., Steele, J. D., Johnstone, E. C. & Lawrie, S. M., Jun 2009, In: Trends in Neurosciences. 32, 6, p. 359-365 7 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Schizophrenia 100%
  • Learning 90%
  • Psychotic Disorders 57%
  • Genes 49%
  • Genetic Variation 29%

• Brain structure and function changes during the development of schizophrenia: The evidence from studies of subjects at increased genetic risk

  Lawrie, S. M., McIntosh, A. M., Hall, J., Owens, D. G. C. & Johnstone, E. C., Mar 2008, In: Schizophrenia Bulletin. 34, 2, p. 330-340 11 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Schizophrenia 100%
  • Brain 60%
  • Genetic Association Studies 26%
  • Cannabis 26%
  • Gray Matter 24%

• Connecting the brain and new drug targets for schizophrenia

  Whalley, H. C., Steele, J. D., Mukherjee, P., Romaniuk, L., McIntosh, A. M., Hall, J. & Lawrie, S. M., 1 Aug 2009, In: Current Pharmaceutical Design. 15, 22, p. 2615-2631 17 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Drug Target 100%
  • Disorder 74%
  • Schizophrenia 71%
  • Neurosciences 46%
  • Drug 46%

• Copy-number variations in DISC1 and DISC1-interacting partners in major mental illness

  Johnstone, M., Maclean, A., Heyrman, L., Lenaerts, A-S., Nordin, A., Nilsson, L-G., De Rijk, P., Goossens, D., Adolfsson, R., St Clair, D. M., Hall, J., Lawrie, S., McIntosh, A., Del-Favero, J., Blackwood, D. & Pickard, B., Oct 2015, In: Molecular Neuropsychiatry. 1, 3

  Research output: Contribution to journal › Literature review › peer-review

  Open Access

  File

  • Overlapping Genes 100%
  • Neurodevelopmental Disorders 79%
  • Protein Binding 67%
  • Mental Disorders 55%
  • Genes 27%

• Magnetic resonance imaging studies in bipolar disorder and schizophrenia: meta-analysis

  Arnone, D., Cavanagh, J., Gerber, D., Lawrie, S. M., Ebmeier, K. P. & McIntosh, A. M., Sep 2009, In: The British Journal of Psychiatry. 195, 3, p. 194-201 8 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Bipolar Disorder 100%
  • Schizophrenia 84%
  • Meta-Analysis 77%
  • Magnetic Resonance Imaging 68%
  • Brain 28%

• Meta-analysis of magnetic resonance imaging studies of the corpus callosum in bipolar disorder

  Arnone, D., McIntosh, A. M., Chandra, P. & Ebmeier, K. P., Nov 2008, In: Acta Psychiatrica Scandinavica. 118, 5, p. 357-362 6 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Corpus Callosum 100%
  • Bipolar Disorder 86%
  • Meta-Analysis 66%
  • Magnetic Resonance Imaging 59%
  • Publication Bias 17%

• Progress in imaging the effects of psychosis susceptibility gene variants

  Redpath, H. L., Lawrie, S. M., Sprooten, E., Whalley, H. C., McIntosh, A. M. & Hall, J., Jan 2013, In: Expert review of neurotherapeutics. 13, 1, p. 37-47 11 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Psychotic Disorders 100%
  • Neuroimaging 96%
  • Schizophrenia 87%
  • Gene-Environment Interaction 44%
  • Genes 43%

• Working memory in schizophrenia: a meta-analysis

  Forbes, N. F., Carrick, L. A., McIntosh, A. M. & Lawrie, S. M., Jun 2009, In: Psychological Medicine. 39, 6, p. 889-905 17 p.

  Research output: Contribution to journal › Literature review › peer-review

  • schizophrenia 100%
  • Short-Term Memory 86%
  • Schizophrenia 74%
  • Meta-Analysis 68%
  • deficit 30%
• Letter

  A GRIK4 variant conferring protection against bipolar disorder modulates hippocampal function

  Whalley, H., Pickard, B. S., McIntosh, A. M., Zuliani, R., Johnstone, E. C., Blackwood, D. H. R., Lawrie, S. M., Muir, W. J. & Hall, J., May 2009, In: Molecular Psychiatry. 14, 5, p. 467-468 2 p.

  Research output: Contribution to journal › Letter › peer-review

• Dermatoglyphics and schizophrenia: Findings from the Edinburgh high risk study [2]

  Langsley, N., Miller, P., Lawrie, S. M., McIntosh, A., Johnstone, E. C. & Byrne, M., 1 Apr 2005, In: Schizophrenia Research. 74, 1, p. 122-124 3 p.

  Research output: Contribution to journal › Letter › peer-review

• Low dose typical antipsychotics - A brief evaluation (multiple letters)

  McIntosh, A. M., Lawri, S. M. & Taylor, D., 1 Jan 2001, In: Psychiatric Bulletin. 25, 7, 1 p.

  Research output: Contribution to journal › Letter › peer-review

• The relationship of anterior thalamic radiation integrity to psychosis risk associated neuregulin-1 variants

  Sprooten, E., Lymer, G. K., Maniega, S. M., McKirdy, J., Clayden, J. D., Bastin, M. E., Porteous, D., Johnstone, E. C., Lawrie, S. M., Hall, J. & McIntosh, A. M., Mar 2009, In: Molecular Psychiatry. 14, 3, p. 237-238 2 p.

  Research output: Contribution to journal › Letter › peer-review