Ann Wheeler

Imaging Facilities Manager, Deanery of Molecular, Genetic and Population Health Sciences

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Personal profile

Biography

I direct the advanced imaging resource which comprises 20 different imaging systems and image informatics. As well as this I work to develop new methodologies relevant to the research carried out at the Human Genetics Unit. I have a particular focus on methodologies applied to super-resolution imaging and development of biocompatible substrates for advanced imaging through the Edinburgh Interdisciplinary Super-Resolution Consortium www.esric.org

Education/Academic qualification

Cell Biology, Doctor of Philosophy (PhD), University of London

21 Sep 2000 → 1 Feb 2005

Award Date: 1 Feb 2005

Molecular and Cellular Biochemistry, Master of Biochemistry, University of Oxford

1 Oct 1995 → 1 Jun 1999

Award Date: 15 Jun 1999

External positions

Committee member European Light Microscopy Initiative

28 May 2016 → …

Committee member, British Society of Cell Biology

1 Oct 2015 → …

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28 Article
2 Chapter (peer-reviewed)
1 Book
1 Poster

Rac1b modulates intestinal tumourigenesis via modulation of Wnt and Egfr signalling pathways
Gudiño, V., Öther-Gee Pohl, S., V Billard, C., Cammareri, P., Bolado Carrancio, A., Aitken, S., Stevenson, D., Hall, A., Agostino, M., Cassidy, J., Nixon, C., von Kriegsheim, A., Friele, P., Popplewell, L., Dickson, G., Murphy, L., Wheeler, A. P., Dunlop, M. G., Din, F. V. N., Strathdee, D. & 2 others, J. Sansom, O. & Myant, K. B., 20 Apr 2021, In: Nature Communications.
Research output: Contribution to journal › Article › peer-review

Open Access
File
cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing
Uggenti, C., Lepelley, A., Depp, M., Badrock, A. P., Rodero, M. P., El-Daher, M-T., Rice, G. I., Dhir, S., Wheeler, A. P., Dhir, A., Albawardi, W., Frémond, M-L., Seabra, L., Doig, J., Blair, N., Martin-Niclos, M. J., Della Mina, E., Rubio-Roldán, A., García-Pérez, J. L., Sproul, D. & 36 others, Rehwinkel, J., Hertzog, J., Boland-Auge, A., Olaso, R., Deleuze, J., Baruteau, J., Brochard, K., Buckley, J., Cavallera, V., Cereda, C., De Waele, L. M. H., Dobbie, A., Doummar, D., Elmslie, F., Koch-Hogrebe, M., Kumar, R., Lamb, K., Livingston, J. H., Majumdar, A., Lorenço, C. M., Orcesi, S., Peudenier, S., Rostasy, K., Salmon, C. A., Scott, C., Tonduti, D., Touati, G., Valente, M., Van Der Linden Jr, H., Van Esch, H., Vermelle, M., Webb, K., Jackson, A. P., Reijns, M. A. M., Gilbert, N. & Crow, Y. J., 31 Dec 2020, In: Nature Genetics. 52, 12, p. 1364-1372 9 p.
Research output: Contribution to journal › Article › peer-review
Periodic propagating waves coordinate RhoGTPase network dynamics at the leading and trailing edges during cell migration
Bolado Carrancio, A., Rukhlenko, O., Nikonova, E., Tsyganov, MA., Wheeler, A. P., Garcia Munoz, A., Kolch, W., von Kriegsheim, A. & Kholodenko, B. N., 24 Jul 2020, In: eLIFE. 9, 58165.
Research output: Contribution to journal › Article › peer-review

Open Access
File
PRL3-DDX21 transcriptional control of endolysosomal genes restricts melanocyte stem cell differentiation
Johansson, J., Marie, K. L., Lu, Y., Brombin, A., Santoriello, C., Zeng, Z., Zich, J., Gautier, P., von Kriegsheim, A., Brunsdon, H., Wheeler, A. P., Dreger, M., Houston, D. R., Dooley, C. M., Sims, A. H., Busch-Nentwich, E. M., Zon, L. I., Illingworth, R. & Patton, E. E., 10 Aug 2020, In: Developmental Cell. 54, 3, p. 317-332.E9 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Liquid crystal lasers for ophthalmics
Dickinson, D., Wheeler, A., Hurd, T. & Hands, P., 15 Apr 2019.
Research output: Contribution to conference › Poster

1 Participation in conference
1 Participation in workshop, seminar, course

ESRIC Summer school
Ann Wheeler (Organiser)
31 Jul 2017 → 4 Aug 2017
Activity: Participating in or organising an event types › Participation in workshop, seminar, course
Edinburgh Super Resolution Summer School
Ann Wheeler (Organiser)
Aug 2014 → Aug 2017
Activity: Participating in or organising an event types › Participation in conference

3 Finished

Multimodal coherent Raman and two-photon fluorescence imaging as a discovery tool in bioscience
Brunton, V., Lee, M. & Wheeler, A.
BBSRC
1/11/20 → 31/03/21
Project: Research
Investigating the Bio-Physical Properties of SAF-A Assembly via Live-Cell SuperResolution Microscopy, Machine Learning and Molecular Dynamics Simulations Proposed
Marenda, M., Gilbert, N., Papadopoulos, D. & Wheeler, A.
Other
1/10/19 → 31/12/20
Project: Research
Beta test of Andor Dragonfly Imaging system
Wheeler, A.
21/03/16 → 2/10/17
Project: Non-Funded Commission or Consultancy work