Search results

  • 2024

    A genome-wide association analysis reveals new pathogenic pathways in gout

    Major, T. J., Takei, R., Matsuo, H., Leask, M., Sumpter, N. A., Topless, R., Shirai, Y., Wang, W., Cadzow, M., Phipps-Green, A., Li, Z., Ji, A., Merriman, M. E., Morice, E., Kelley, E. E., Wei, W-H., McCormick, S. P. A., Bixley, M. J., Reynolds, R. J., Saag, K. G., & 78 othersFadason, T., Golovina, E., O'Sullivan, J. M., Stamp, L. K., Dalbeth, N., Abhishek, A., Doherty, M., Roddy, E., Jacobsson, L. T. H., Kapetanovic, M. C., Melander, O., Andres, M., Perez-Ruiz, F., Torres, R. J., Radstake, T., Jansen, T. L., Janssen, M., Joosten, L. A. B., Liu, R., Gaal, O. I., Crisan, T. O., Rednic, S., Kurreeman, F., Huizinga, T. W. J., Toes, R., Lioté, F., Richette, P., Bardin, T., Ea, H. K., Pascart, T., McCarthy, G. M., Helbert, L., Stiburkova, B., Tausche, A-K., Uhlig, T., Vitart, V., Boutin, T. S., Hayward, C., Riches, P., Ralston, S. H., Campbell, A., Macdonald, T. M., Nakayama, A., Takada, T., Nakatochi, M., Shimizu, S., Kawamura, Y., Toyoda, Y., Nakaoka, H., Yamamoto, K., Matsuo, K., Shinomiya, N., Ichida, K., Lee, C., Bradbury, L. A., Brown, M. A., Robinson, P. C., Buchanan, R. R. C., Hill, C. L., Lester, S., Smith, M. D., Rischmueller, M., Choi, H. K., Stahl, E. A., Miner, J. N., Solomon, D. H., Cui, J., Giacomini, K. M., Brackman, D. J., Jorgenson, E. M., Liu, H., Susztak, K., Shringarpure, S., So, A., Okada, Y., Li, C., Shi, Y. & Merriman, T. R., 15 Oct 2024, (E-pub ahead of print) In: Nature Genetics.

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  • Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization

    EPIC-InterAct Consortium, Willems, S. M., Campbell, A., Davies, G., Pattie, A., Redmond, P., Deary, I. J., Hayward, C., Morris, A. P., Porteous, D., Rudan, I., Morris, A. P. & Barroso, I., 30 Sept 2024, In: Wellcome Open Research. 8, 33 p., 483.

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  • Understanding the genetic complexity of puberty timing across the allele frequency spectrum

    Kentistou, K. A., Kaisinger, L. R., Stankovic, S., Vaudel, M., Mendes de oliveira, E., Messina, A., Walters, R. G., Liu, X., Busch, A. S., Helgason, H., Thompson, D. J., Santoni, F., Petricek, K. M., Zouaghi, Y., Huang-Doran, I., Gudbjartsson, D. F., Bratland, E., Lin, K., Gardner, E. J., Zhao, Y., & 203 othersJia, R. Y., Terao, C., Riggan, M. J., Bolla, M. K., Yazdanpanah, M., Yazdanpanah, N., Bradfield, J. P., Broer, L., Campbell, A., Chasman, D. I., Cousminer, D. L., Franceschini, N., Franke, L. H., Girotto, G., He, C., Järvelin, M-R., Joshi, P. K., Kamatani, Y., Karlsson, R., Luan, J., Lunetta, K. L., Mägi, R., Mangino, M., Medland, S. E., Meisinger, C., Noordam, R., Nutile, T., Concas, M. P., Polašek, O., Porcu, E., Ring, S. M., Sala, C., Smith, A. V., Tanaka, T., Van der most, P. J., Vitart, V., Wang, C. A., Willemsen, G., Zygmunt, M., Ahearn, T. U., Andrulis, I. L., Anton-Culver, H., Antoniou, A. C., Auer, P. L., Barnes, C. L. K., Beckmann, M. W., Berrington de gonzalez, A., Bogdanova, N. V., Bojesen, S. E., Brenner, H., Buring, J. E., Canzian, F., Chang-Claude, J., Couch, F. J., Cox, A., Crisponi, L., Czene, K., Daly, M. B., Demerath, E. W., Dennis, J., Devilee, P., De vivo, I., Dörk, T., Dunning, A. M., Dwek, M., Eriksson, J. G., Fasching, P. A., Fernandez-Rhodes, L., Ferreli, L., Fletcher, O., Gago-Dominguez, M., García-Closas, M., García-Sáenz, J. A., González-Neira, A., Grallert, H., Guénel, P., Haiman, C. A., Hall, P., Hamann, U., Hakonarson, H., Hart, R. J., Hickey, M., Hooning, M. J., Hoppe, R., Hopper, J. L., Hottenga, J-J., Hu, F. B., Huebner, H., Hunter, D. J., Jernström, H., John, E. M., Karasik, D., Khusnutdinova, E. K., Kristensen, V. N., Lacey, J. V., Lambrechts, D., Launer, L. J., Lind, P. A., Lindblom, A., Magnusson, P. K. E., Mannermaa, A., Mccarthy, M. I., Meitinger, T., Menni, C., Michailidou, K., Millwood, I. Y., Milne, R. L., Montgomery, G. W., Nevanlinna, H., Nolte, I. M., Nyholt, D. R., Obi, N., O’brien, K. M., Offit, K., Oldehinkel, A. J., Ostrowski, S. R., Palotie, A., Pedersen, O. B., Peters, A., Pianigiani, G., Plaseska-Karanfilska, D., Pouta, A., Pozarickij, A., Radice, P., Rennert, G., Rosendaal, F. R., Ruggiero, D., Saloustros, E., Sandler, D. P., Schipf, S., Schmidt, C. O., Schmidt, M. K., Small, K., Spedicati, B., Stampfer, M., Stone, J., Tamimi, R. M., Teras, L. R., Tikkanen, E., Turman, C., Vachon, C. M., Wang, Q., Winqvist, R., Wolk, A., Zemel, B. S., Zheng, W., Van dijk, K. W., Alizadeh, B. Z., Bandinelli, S., Boerwinkle, E., Boomsma, D. I., Ciullo, M., Chenevix-Trench, G., Cucca, F., Esko, T., Gieger, C., Grant, S. F. A., Gudnason, V., Hayward, C., Kolčić, I., Kraft, P., Lawlor, D. A., Martin, N. G., Nøhr, E. A., Pedersen, N. L., Pennell, C. E., Ridker, P. M., Robino, A., Snieder, H., Sovio, U., Spector, T. D., Stöckl, D., Sudlow, C., Timpson, N. J., Toniolo, D., Uitterlinden, A., Ulivi, S., Völzke, H., Wareham, N. J., Widen, E., Wilson, J. F., John, E. M., Hall, P., Winqvis, R., Pharoah, P. D. P., Li, L., Easton, D. F., Njølstad, P. R., Sulem, P., Murabito, J. M., Murray, A., Manousaki, D., Juul, A., Erikstrup, C., Stefansson, K., Horikoshi, M., Chen, Z., Farooqi, I. S., Pitteloud, N., Johansson, S., Day, F. R., Perry, J. R. B. & Ong, K. K., 1 Jul 2024, In: Nature Genetics.

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  • Generation Scotland: an update on Scotland's longitudinal family health study

    Milbourn, H., McCartney, D., Richmond, A., Campbell, A., Flaig, R., Robertson, S., Fawns-Ritchie, C., Hayward, C., Marioni, R. E., McIntosh, A. M., Porteous, D. J., Whalley, H. C. & Sudlow, C., 21 Jun 2024, In: BMJ Open. 14, 6, e084719.

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  • Generation Scotland: an update on Scotland’s longitudinal family health study

    Milbourn, H., Mccartney, D., Richmond, A., Campbell, A., Flaig, R., Robertson, S., Fawns-Ritchie, C., Hayward, C., Marioni, R. E., Mcintosh, A. M., Porteous, D. J., Whalley, H. C. & Sudlow, C., 1 Jun 2024, (E-pub ahead of print) In: BMJ Open. 14, 6, p. e084719

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  • The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses

    Walker, R. M., Chong, M., Perrot, N., Pigeyre, M., Gadd, D. A., Stolicyn, A., Shi, L., Campbell, A., Shen, X., Whalley, H. C., Nevado-Holgado, A., McIntosh, A. M., Heitmeier, S., Rangarajan, S., O'Donnell, M., Smith, E. E., Yusuf, S., Whiteley, W. N. & Paré, G., 18 May 2024, In: Translational Psychiatry. 14, 1, p. 204

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  • Blood-based epigenome-wide analyses of chronic low-grade inflammation across diverse population cohorts

    Hillary, R. F., Ng, H. K., McCartney, D. L., Elliott, H. R., Walker, R. M., Campbell, A., Huang, F., Direk, K., Welsh, P., Sattar, N., Corley, J., Hayward, C., McIntosh, A. M., Sudlow, C., Evans, K. L., Cox, S. R., Chambers, J. C., Loh, M., Relton, C. L., Marioni, R. E., & 2 othersYousefi, P. D. & Suderman, M., 8 May 2024, In: Cell Genomics. 4, 5, 100544.

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  • Blood-based epigenome-wide analysis of chronic low-grade inflammation across diverse population cohorts

    Hillary, R., McCartney, D. L., Elliott, H. R., Walker, R. M., Campbell, A., Huang, F., Direk, K., Welsh, P., Sattar, N., Hayward, C., McIntosh, A. M., Sudlow, C. L. M., Evans, K., Cox, S. R., Relton, C. L., Marioni, R. E., Yousefi, P. D. & Suderman, M. J., 8 May 2024, In: Cell Genomics. 4, 5, 29 p., 100544.

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  • Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits

    Keaton, J. M., Kamali, Z., Xie, T., Vaez, A., Williams, A., Goleva, S. B., Ani, A., Evangelou, E., Hellwege, J. N., Yengo, L., Young, W. J., Traylor, M., Giri, A., Zheng, Z., Zeng, J., Chasman, D. I., Morris, A. P., Caulfield, M. J., Hwang, S-J., Kooner, J. S., & 131 othersConen, D., Attia, J. R., Morrison, A. C., Loos, R. J. F., Kristiansson, K., Schmidt, R., Hicks, A. A., Pramstaller, P. P., Nelson, C. P., Samani, N. J., Risch, L., Gyllensten, U., Melander, O., Riese, H., Wilson, J. F., Campbell, H., Rich, S. S., Psaty, B. M., Lu, Y., Rotter, J. I., Guo, X., Rice, K. M., Vollenweider, P., Sundström, J., Langenberg, C., Tobin, M. D., Giedraitis, V., Luan, J., Tuomilehto, J., Kutalik, Z., Ripatti, S., Salomaa, V., Girotto, G., Trompet, S., Jukema, J. W., van der Harst, P., Ridker, P. M., Giulianini, F., Vitart, V., Goel, A., Watkins, H., Harris, S. E., Deary, I. J., van der Most, P. J., Oldehinkel, A. J., Keavney, B. D., Hayward, C., Campbell, A., Boehnke, M., Scott, L. J., Boutin, T., Mamasoula, C., Järvelin, M-R., Peters, A., Gieger, C., Lakatta, E. G., Cucca, F., Hui, J., Knekt, P., Enroth, S., De Borst, M. H., Polašek, O., Concas, M. P., Catamo, E., Cocca, M., Li-Gao, R., Hofer, E., Schmidt, H., Spedicati, B., Waldenberger, M., Strachan, D. P., Laan, M., Teumer, A., Dörr, M., Gudnason, V., Cook, J. P., Ruggiero, D., Kolcic, I., Boerwinkle, E., Traglia, M., Lehtimäki, T., Raitakari, O. T., Johnson, A. D., Newton-Cheh, C., Brown, M. J., Dominiczak, A. F., Sever, P. J., Poulter, N., Chambers, J. C., Elosua, R., Siscovick, D., Esko, T., Metspalu, A., Strawbridge, R. J., Laakso, M., Hamsten, A., Hottenga, J-J., de Geus, E., Morris, A. P., Palmer, C. N. A., Nolte, I. M., Milaneschi, Y., Marten, J., Wright, A., Zeggini, E., Howson, J. M. M., O’Donnell, C. J., Spector, T., Nalls, M. A., Simonsick, E. M., Liu, Y., van Duijn, C. M., Butterworth, A. S., Danesh, J. N., Menni, C., Wareham, N. J., Khaw, K-T., Sun, Y. V., Wilson, P. W. F., Cho, K., Visscher, P. M., Denny, J. C., Program, M. V., Study, L. C., consortium, CHARGE., Consortium, ICBP., Levy, D., Edwards, T. L., Munroe, P. B., Snieder, H. & Warren, H. R., May 2024, In: Nature Genetics. 56, 5, p. 778-791 14 p.

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  • Disrupted limbic-prefrontal effective connectivity in response to fearful faces in lifetime depression

    Stolicyn, A., Harris, M. A., De Nooij, L., Shen, X., Macfarlane, J. A., Campbell, A., McNeil, C. J., Sandu, A-L., Murray, A. D., Waiter, G. D., Lawrie, S. M., Steele, J. D., McIntosh, A. M., Romaniuk, L. & Whalley, H. C., 15 Apr 2024, In: Journal of Affective Disorders (JAD). 351, p. 983-993

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  • Epigenetic scores of blood-based proteins as biomarkers of general cognitive function and brain health

    Smith, H. M., Moodie, J. E., Monterrubio-Gómez, K., Gadd, D. A., Hillary, R. F., Chybowska, A. D., Mccartney, D. L., Campbell, A., Redmond, P., Page, D., Taylor, A., Corley, J., Harris, S. E., Valdés hernández, M., Muñoz maniega, S., Bastin, M. E., Wardlaw, J. M., Deary, I. J., Boardman, J. P., Mullin, D. S., & 3 othersRuss, T. C., Cox, S. R. & Marioni, R. E., 25 Mar 2024, In: Clinical Epigenetics. 16, 1

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  • Prioritization of Kidney Cell Types Highlights Myofibroblast Cells in Regulating Human Blood Pressure

    Ganji-Arjenaki, M., Kamali, Z., International Consortium of Blood Pressure, Sardari, S., de Borst, M., Snieder, H., Vaez, A., Campbell, A., Campbell, H., Rudan, I., Wilson, J. F., Hayward, C., Vitart, V. & Wild, S. H., 13 Mar 2024, In: Kidney International Reports. 9, 6, p. 1849-1859 11 p.

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  • Epigenetic Contributions to Clinical Risk Prediction of Cardiovascular Disease

    Chybowska, A. D., Gadd, D. A., Cheng, Y., Bernabeu, E., Campbell, A., Walker, R. M., McIntosh, A. M., Wrobel, N., Murphy, L., Welsh, P., Sattar, N., Price, J. F., McCartney, D. L., Evans, K. L. & Marioni, R. E., 30 Jan 2024, (E-pub ahead of print) In: Circulation: Genomic and Precision Medicine. p. e004265

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  • X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements

    Scholz, M., Horn, K., Pott, J., Wuttke, M., Kühnapfel, A., Nasr, M. K., Kirsten, H., Li, Y., Hoppmann, A., Gorski, M., Ghasemi, S., Li, M., Tin, A., Chai, J-F., Cocca, M., Wang, J., Nutile, T., Akiyama, M., Åsvold, B. O., Bansal, N., & 139 othersBiggs, M. L., Boutin, T., Brenner, H., Brumpton, B., Burkhardt, R., Cai, J., Campbell, A., Campbell, H., Chalmers, J., Chasman, D. I., Chee, M. L., Chee, M. L., Chen, X., Cheng, C-Y., Cifkova, R., Daviglus, M., Delgado, G., Dittrich, K., Edwards, T. L., Endlich, K., Michael Gaziano, J., Giri, A., Giulianini, F., Gordon, S. D., Gudbjartsson, D. F., Hallan, S., Hamet, P., Hartman, C. A., Hayward, C., Heid, I. M., Hellwege, J. N., Holleczek, B., Holm, H., Hutri-Kähönen, N., Hveem, K., Isermann, B., Jonas, J. B., Joshi, P. K., Kamatani, Y., Kanai, M., Kastarinen, M., Khor, C. C., Kiess, W., Kleber, M. E., Körner, A., Kovacs, P., Krajcoviechova, A., Kramer, H., Krämer, B. K., Kuokkanen, M., Kähönen, M., Lange, L. A., Lash, J. P., Lehtimäki, T., Li, H., Lin, B. M., Liu, J., Loeffler, M., Lyytikäinen, L-P., Magnusson, P. K. E., Martin, N. G., Matsuda, K., Milaneschi, Y., Mishra, P. P., Mononen, N., Montgomery, G. W., Mook-Kanamori, D. O., Mychaleckyj, J. C., März, W., Nauck, M., Nikus, K., Nolte, I. M., Noordam, R., Okada, Y., Olafsson, I., Oldehinkel, A. J., Penninx, B. W. J. H., Perola, M., Pirastu, N., Polasek, O., Porteous, D. J., Poulain, T., Psaty, B. M., Rabelink, T. J., Raffield, L. M., Raitakari, O. T., Rasheed, H., Reilly, D. F., Rice, K. M., Richmond, A., Ridker, P. M., Rotter, J. I., Rudan, I., Sabanayagam, C., Salomaa, V., Schneiderman, N., Schöttker, B., Sims, M., Snieder, H., Stark, K. J., Stefansson, K., Stocker, H., Stumvoll, M., Sulem, P., Sveinbjornsson, G., Svensson, P. O., Tai, E-S., Taylor, K. D., Tayo, B. O., Teren, A., Tham, Y-C., Thiery, J., Thio, C. H. L., Thomas, L. F., Tremblay, J., Tönjes, A., van der Most, P. J., Vitart, V., Völker, U., Wang, Y. X., Wang, C., Wei, W. B., Whitfield, J. B., Wild, S. H., Wilson, J. F., Winkler, T. W., Wong, T-Y., Woodward, M., Sim, X., Chu, A. Y., Feitosa, M. F., Thorsteinsdottir, U., Hung, A. M., Teumer, A., Franceschini, N., Parsa, A., Köttgen, A., Schlosser, P. & Pattaro, C., 18 Jan 2024, In: Nature Communications. 15, 1, p. 586

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  • 2023

    GDF15 linked to maternal risk of nausea and vomiting during pregnancy

    Fejzo, M., Rocha, N., Cimino, I., Lockhart, S. M., Petry, C. J., Kay, R. G., Burling, K., Barker, P., George, A. L., Yasara, N., Premawardhena, A., Gong, S., Cook, E., Rimmington, D., Rainbow, K., Withers, D. J., Cortessis, V., Mullin, P. M., MacGibbon, K. W., Jin, E., & 23 othersKam, A., Campbell, A., Polasek, O., Tzoneva, G., Gribble, F. M., Yeo, G. S. H., Lam, B. Y. H., Saudek, V., Hughes, I. A., Ong, K. K., Perry, J. R. B., Sutton Cole, A., Baumgarten, M., Welsh, P., Sattar, N., Smith, G. C. S., Charnock-Jones, D. S., Coll, A. P., Meek, C. L., Mettananda, S., Hayward, C., Mancuso, N. & O'Rahilly, S., 13 Dec 2023, (E-pub ahead of print) In: Nature.

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  • Multiple cardiac biomarkers to improve prediction of cardiovascular events: Findings from the Generation Scotland Scottish Family Health Study

    Welsh, P., Kimenai, D. M., Shah, A. S. V., Gadd, D. A., Marioni, R. E., Woodward, M., Sudlow, C. L. M., Campbell, A., Cleland, J. G. F., Pellicori, P., Hayward, C., Mills, N. L. & Sattar, N., 9 Dec 2023, In: Clinical Chemistry.

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  • Integration of datasets for individual prediction of DNA methylation-based biomarkers

    Merzbacher, C., Ryan, B., Goldsborough, T., Hillary, R. F., Campbell, A., Murphy, L., McIntosh, A. M., Liewald, D., Harris, S. E., Mcrae, A. F., Cox, S. R., Cannings, T. I., Vallejos, C. A., McCartney, D. L. & Marioni, R. E., 5 Dec 2023, In: Genome Biology. 24, 1, p. 278

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  • Meta-Analyses of Genome-Wide Association Studies for Postpartum Depression

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Dec 2023, In: The American Journal of Psychiatry. 180, p. 884-895

    Research output: Contribution to journalArticlepeer-review

  • Genome-wide association study of susceptibility to hospitalised respiratory infections

    Regeneron Genomics Center, Williams, A. T., Shrine, N., Naghra-van Gijzel, H., Betts, J. C., Chen, J., Hessel, E. M., John, C., Packer, R., Reeve, N. F., Yeo, A. J., Abner, E., Åsvold, B. O., Auvinen, J., Bartz, T. M., Bradford, Y., Brumpton, B., Campbell, A., Cho, M. H., Chu, S., & 28 othersCrosslin, D. R., Feng, Q., Esko, T., Gharib, S. A., Hayward, C., Hebbring, S., Hveem, K., Järvelin, M-R., Jarvik, G. P., Landis, S. H., Larson, E. B., Liu, J., Loos, R. J. F., Luo, Y., Moscati, A., Mullerova, H., Namjou, B., Porteous, D. J., Quint, J. K., Ritchie, M. D., Sliz, E., Stanaway, I. B., Thomas, L., Wilson, J. F., Hall, I. P., Wain, L. V., Michalovich, D. & Tobin, M. D., 21 Nov 2023, In: Wellcome Open Research. 6, 25 p., 290.

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  • Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci

    de las Fuentes, L., Schwander, K. L., Brown, M. R., Bentley, A. R., Winkler, T. W., Sung, Y. J., Munroe, P. B., Miller, C. L., Aschard, H., Aslibekyan, S., Bartz, T. M., Bielak, L. F., Chai, J. F., Cheng, C-Y., Dorajoo, R., Feitosa, M. F., Guo, X., Hartwig, F. P., Horimoto, A., Kolčić, I., & 178 othersLim, E., Liu, Y., Manning, A. K., Marten, J., Musani, S. K., Noordam, R., Padmanabhan, S., Rankinen, T., Richard, M. A., Ridker, P. M., Smith, A. V., Vojinovic, D., Zonderman, A. B., Alver, M., Boissel, M., Christensen, K., Freedman, B. I., Gao, C., Giulianini, F., Harris, S. E., He, M., Hsu, F-C., Kühnel, B., Laguzzi, F., Li, X., Lyytikäinen, L-P., Nolte, I. M., Poveda, A., Rauramaa, R., Riaz, M., Robino, A., Sofer, T., Takeuchi, F., Tayo, B. O., van der Most, P. J., Verweij, N., Ware, E. B., Weiss, S., Wen, W., Yanek, L. R., Zhan, Y., Amin, N., Arking, D. E., Ballantyne, C., Boerwinkle, E., Brody, J. A., Broeckel, U., Campbell, A., Canouil, M., Chai, X., Chen, Y-D. I., Chen, X., Chitrala, K. N., Concas, M. P., de Faire, U., de Mutsert, R., de Silva, H. J., de Vries, P. S., Do, A., Faul, J. D., Fisher, V., Floyd, J. S., Forrester, T., Friedlander, Y., Girotto, G., Gu, C. C., Hallmans, G., Heikkinen, S., Heng, C-K., Homuth, G., Hunt, S., Ikram, M. A., Jacobs Jr, D. R., Kavousi, M., Khor, C. C., Kilpeläinen, T. O., Koh, W-P., Komulainen, P., Langefeld, C. D., Liang, J., Liu, K., Liu, J., Lohman, K., Mägi, R., Manichaikul, A. W., McKenzie, C. A., Meitinger, T., Milaneschi, Y., Nauck, M., Nelson, C. P., O’Connell, J. R., Palmer, N. D., Pereira, A. C., Perls, T., Peters, A., Polašek, O., Raitakari, O. T., Rice, K., Rice, T. K., Rich, S. S., Sabanayagam, C., Schreiner, P. J., Shu, X-O., Sidney, S., Sims, M., Smith, J. A., Starr, J. M., Strauch, K., Tai, E. S., Taylor, K. D., Tsai, M. Y., Uitterlinden, A. G., van Heemst, D., Waldenberger, M., Wang, Y-X., Wei, W-B., Wilson, G., Xuan, D., Yao, J., Yu, C., Yuan, J-M., Zhao, W., Becker, D. M., Bonnefond, A., Bowden, D. W., Cooper, R. S., Deary, I. J., Divers, J., Esko, T., Franks, P. W., Froguel, P., Gieger, C., Jonas, J. B., Kato, N., Lakka, T. A., Leander, K., Lehtimäki, T., Magnusson, P. K. E., North, K. E., Ntalla, I., Penninx, B., Samani, N. J., Snieder, H., Spedicati, B., van der Harst, P., Völzke, H., Wagenknecht, L. E., Weir, D. R., Wojczynski, M. K., Wu, T., Zheng, W., Zhu, X., Bouchard, C., Chasman, D. I., Evans, M. K., Fox, E. R., Gudnason, V., Hayward, C., Horta, B. L., Kardia, S. L. R., Krieger, J. E., Mook-Kanamori, D. O., Peyser, P. A., Province, M. M., Psaty, B. M., Rudan, I., Sim, X., Smith, B. H., van Dam, R. M., van Duijn, C. M., Wong, T. Y., Arnett, D. K., Rao, D. C., Gauderman, J., Liu, C-T., Morrison, A. C., Rotter, J. I. & Fornage, M., Nov 2023, In: Frontiers in Genetics. 14, 16 p., 1235337.

    Research output: Contribution to journalArticlepeer-review

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  • Elevated symptoms of depression and anxiety among family members and friends of critically ill COVID-19 patients – an observational study of five cohorts across four countries

    Lovik, A., González-Hijón, J., Hoffart, A., Fawns-Ritchie, C., Magnúsdóttir, I., Lu, L., Unnarsdóttir, A. B., Kähler, A. K., Campbell, A., Hauksdóttir, A., Chourpiliadis, C., McCartney, D. L., Thordardottir, E. B., Joyce, E. E., Frans, E. M., Jakobsdottir, J., Trogstad, L., Andreassen, O. A., Magnus, P., Johnson, S. U., & 7 othersSullivan, P. F., Aspelund, T., Porteous, D. J., Ask, H., Ebrahimi, O. V., Valdimarsdóttir, U. A. & Fang, F., Oct 2023, In: The Lancet Regional Health - Europe. 33, 100733.

    Research output: Contribution to journalArticlepeer-review

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  • Prognosis and Personalized In Silico Prediction of Treatment Efficacy in Cardiovascular and Chronic Kidney Disease: A Proof-of-Concept Study

    Jaimes Campos, M. A., Andújar, I., Keller, F., Mayer, G., Rossing, P., Staessen, J. A., Delles, C., Beige, J., Glorieux, G., Clark, A. L., Mullen, W., Schanstra, J. P., Vlahou, A., Rossing, K., Peter, K., Ortiz, A., Campbell, A., Persson, F., Latosinska, A., Mischak, H., & 2 othersSiwy, J. & Jankowski, J., 14 Sept 2023, In: Pharmaceuticals. 16, 9, 1298.

    Research output: Contribution to journalArticlepeer-review

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  • Genetic insights into resting heart rate and its role in cardiovascular disease

    DCCT/EDIC Research Group, Campbell, A., Schraut, K. E., Joshi, P. K., Hayward, C., Porteous, D. J., Wilson, J. F. & van der Harst, P., 2 Aug 2023, In: Nature Communications. 14, 1, 21 p., 4646.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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  • Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases

    NBCS Collaborators, Figlioli, G., Billaud, A., Wang, Q., Bolla, M. K., Dennis, J., Lush, M., Kvist, A., Adank, M. A., Ahearn, T. U., Antonenkova, N. N., Auvinen, P., Behrens, S., Bermisheva, M., Bogdanova, N. V., Bojesen, S. E., Bonanni, B., Brüning, T., Camp, N. J., Campbell, A., & 61 othersCastelao, J. E., Cessna, M. H., Czene, K., Devilee, P., Dörk, T., Eriksson, M., Fasching, P. A., Flyger, H., Gabrielson, M., Gago-Dominguez, M., García-Closas, M., Glendon, G., Gómez Garcia, E. B., González-Neira, A., Grassmann, F., Guénel, P., Hahnen, E., Hamann, U., Hillemanns, P., Hooning, M. J., Hoppe, R., Howell, A., Humphreys, K., Jakubowska, A., Khusnutdinova, E. K., Kristensen, V. N., Lindblom, A., Loizidou, M. A., Lubiński, J., Mannermaa, A., Maurer, T., Mavroudis, D., Newman, W. G., Obi, N., Panayiotidis, M. I., Radice, P., Rashid, M. U., Rhenius, V., Ruebner, M., Saloustros, E., Sawyer, E. J., Schmidt, M. K., Schmutzler, R. K., Shah, M., Southey, M. C., Tomlinson, I., Truong, T., van Veen, E. M., Wendt, C., Yang, X. R., Michailidou, K., Dunning, A. M., Pharoah, P. D. P., Easton, D. F., Andrulis, I. L., Evans, D. G., Hollestelle, A., Chang-Claude, J., Milne, R. L., Peterlongo, P. & Investigators, K., 23 Jun 2023, In: Cancers. 15, 13, 16 p., 3313.

    Research output: Contribution to journalArticlepeer-review

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  • Understanding the genetic complexity of puberty timing across the allele frequency spectrum

    ABCTB Investigators, 20 Jun 2023, medRxiv.

    Research output: Working paperPreprint

  • Genome-wide association study of chronic sputum production implicates loci involved in mucus production and infection

    Packer, R. J., Shrine, N., Hall, R., Melbourne, C. A., Thompson, R., Williams, A. T., Paynton, M. L., Guyatt, A. L., Allen, R. J., Lee, P. H., John, C., Campbell, A., Hayward, C., de Vries, M., Vonk, J. M., Davitte, J., Hessel, E., Michalovich, D., Betts, J. C., Sayers, I., & 4 othersYeo, A., Hall, I. P., Tobin, M. D. & Wain, L. V., 1 Jun 2023, (E-pub ahead of print) In: European Respiratory Journal. 61, 6, 2201667.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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  • Phenome-wide analyses identify an association between the parent-of-origin effects dependent methylome and the rate of aging in humans

    Gao, C., Amador, C., Walker, R., Campbell, A., Madden, R., Adams, M. J., Bai, X., Liu, Y., Li, M., Hayward, C., Porteous, D. J., Shen, X., Evans, K. L., Haley, C. S., McIntosh, A. M., Navarro, P. & Zeng, Y., 15 May 2023, In: Genome Biology. 24, p. 1-28 28 p., 117.

    Research output: Contribution to journalArticlepeer-review

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  • Development and validation of DNA Methylation scores in two European cohorts augment 10-year risk prediction of type 2 diabetes

    Cheng, Y., Gadd, D., Gieger, C., Monterrubio-Gomez, K., Zhang, Y., Berta, I., Stam, M., Szlachetka, N., Lobzaev, E., Wrobel, N., Murphy, L., Campbell, A., Nangle, C., Walker, R., Fawns-Ritchie, C., Peters, A., Rathmann, W., Porteous, D. J., Evans, K. L., McIntosh, A. M., & 6 othersCannings, T. I., Waldenberger, M., Ganna, A., McCartney, D. L., Vallejos, C. A. & Marioni, R. E., 6 Apr 2023, In: Nature Aging. 3, p. 450–458

    Research output: Contribution to journalArticlepeer-review

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  • Impact of preeclampsia on cardiovascular events: an analysis of the Generation Scotland: Scottish Family Health Study

    Brown, C. E., Casey, H., Dominiczak, A. F., Kerr, S., Campbell, A. & Delles, C., 27 Mar 2023, In: Journal of Human Hypertension.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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  • Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease

    Young, W. J., Haessler, J., Benjamins, J-W., Repetto, L., Yao, J., Isaacs, A., Harper, A. R., Ramirez, J., Garnier, S., van Duijvenboden, S., Baldassari, A. R., Concas, M. P., Duong, T., Foco, L., Isaksen, J. L., Mei, H., Noordam, R., Nursyifa, C., Richmond, A., Santolalla, M. L., & 74 othersSitlani, C. M., Soroush, N., Thériault, S., Trompet, S., Aeschbacher, S., Ahmadizar, F., Alonso, A., Brody, J. A., Campbell, A., Correa, A., Darbar, D., De Luca, A., Deleuze, J-F., Ellervik, C., Fuchsberger, C., Goel, A., Grace, C., Guo, X., Hansen, T., Heckbert, S. R., Jackson, R. D., Kors, J. A., Lima-Costa, M. F., Linneberg, A., Macfarlane, P. W., Morrison, A. C., Navarro, P., Porteous, D. J., Pramstaller, P. P., Reiner, A. P., Risch, L., Schotten, U., Shen, X., Sinagra, G., Soliman, E. Z., Stoll, M., Tarazona-Santos, E., Tinker, A., Trajanoska, K., Villard, E., Warren, H. R., Whitsel, E. A., Wiggins, K. L., Arking, D. E., Avery, C. L., Conen, D., Girotto, G., Grarup, N., Hayward, C., Jukema, J. W., Mook-Kanamori, D. O., Olesen, M. S., Padmanabhan, S., Psaty, B. M., Pattaro, C., Ribeiro, A. L. P., Rotter, J. I., Stricker, B. H., van der Harst, P., van Duijn, C. M., Verweij, N., Wilson, J. G., Orini, M., Charron, P., Watkins, H., Kooperberg, C., Lin, H. J., Wilson, J. F., Kanters, J. K., Sotoodehnia, N., Mifsud, B., Lambiase, P. D., Tereshchenko, L. G. & Munroe, P. B., 14 Mar 2023, In: Nature Communications. 14, 1, 16 p., 1411.

    Research output: Contribution to journalArticlepeer-review

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  • Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

    China Kadoorie Biobank Collaborative Group & Cox, S. R., 13 Mar 2023, In: Nature Genetics. 55, 3, p. 410-422 13 p.

    Research output: Contribution to journalArticlepeer-review

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  • The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

    Rahmioglu, N., Mortlock, S., Ghiasi, M., Møller, P. L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M. H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., Nõukas, M., Perro, D., Sliz, E., & 126 othersSobalska-Kwapis, M., Thorleifsson, G., Topbas-Selcuki, N. F., Vitonis, A., Westergaard, D., Arnadottir, R., Burgdorf, K. S., Campbell, A., Cheuk, C. S. K., Clementi, C., Cook, J., De vivo, I., Divasta, A., Dorien, O., Donoghue, J. F., Edwards, T., Fontanillas, P., Fung, J. N., Geirsson, R. T., Girling, J. E., Harkki, P., Harris, H. R., Healey, M., Heikinheimo, O., Holdsworth-Carson, S., Hostettler, I. C., Houlden, H., Houshdaran, S., Irwin, J. C., Jarvelin, M., Kamatani, Y., Kennedy, S. H., Kepka, E., Kettunen, J., Kubo, M., Kulig, B., Kurra, V., Laivuori, H., Laufer, M. R., Lindgren, C. M., Macgregor, S., Mangino, M., Martin, N. G., Matalliotaki, C., Matalliotakis, M., Murray, A. D., Ndungu, A., Nezhat, C., Olsen, C. M., Opoku-Anane, J., Padmanabhan, S., Paranjpe, M., Peters, M., Polak, G., Porteous, D. J., Rabban, J., Rexrode, K. M., Romanowicz, H., Saare, M., Saavalainen, L., Schork, A. J., Sen, S., Shafrir, A. L., Siewierska-Górska, A., Słomka, M., Smith, B. H., Smolarz, B., Szaflik, T., Szyłło, K., Takahashi, A., Terry, K. L., Tomassetti, C., Treloar, S. A., Vanhie, A., Vincent, K., Vo, K. C., Werring, D. J., Zeggini, E., Zervou, M. I., Stefansson, K., Nyegaard, M., Harkki, P., Heikinheimo, O., Kettunen, J., Kurra, V., Laivuori, H., Uimari, O., Galarneau, G., Clementi, C., Yurttas-Beim, P., Fontanillas, P., Tung, J. Y., Adachi, S., Buring, J. E., Ridker, P. M., D’hooghe, T., Goulielmos, G. N., Hapangama, D. K., Hayward, C., Horne, A. W., Low, S., Martikainen, H., Chasman, D. I., Rogers, P. A. W., Saunders, P. T., Sirota, M., Spector, T., Strapagiel, D., Tung, J. Y., Whiteman, D. C., Giudice, L. C., Velez-Edwards, D. R., Uimari, O., Kraft, P., Salumets, A., Nyholt, D. R., Mägi, R., Stefansson, K., Becker, C. M., Yurttas-Beim, P., Steinthorsdottir, V., Nyegaard, M., Missmer, S. A., Montgomery, G. W., Morris, A. P. & Zondervan, K. T., 1 Mar 2023, (E-pub ahead of print) In: Nature Genetics. 55, 3, p. 423-436

    Research output: Contribution to journalArticlepeer-review

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  • Refining epigenetic prediction of chronological and biological age

    Bernabeu, E., McCartney, D. L., Gadd, D., Hillary, R., Lu, A. T., Murphy, L., Wrobel, N., Campbell, A., Harris, S. E., Liewald, D. C., Hayward, C., Sudlow, C. L. M., Cox, S. R., Evans, K. L., Horvath, S., McIntosh, A. M., Robinson, M. R., Vallejos, C. A. & Marioni, R. E., 28 Feb 2023, In: Genome Medicine. 15, 1, 12.

    Research output: Contribution to journalArticlepeer-review

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  • Opioid medication use and blood DNA methylation: epigenome-wide association meta-analysis

    Lee, M., Joehanes, R., McCartney, D. L., Kho, M., Hüls, A., Wyss, A. B., Liu, C., Walker, R. M., R Kardia, S. L., Wingo, T. S., Burkholder, A., Ma, J., Campbell, A., Wingo, A. P., Huan, T., Sikdar, S., Keshawarz, A., Bennett, D. A., Smith, J. A., Evans, K. L., & 2 othersLevy, D. & London, S. J., 26 Jan 2023, (E-pub ahead of print) In: Epigenomics.

    Research output: Contribution to journalArticlepeer-review

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  • Structural brain correlates of childhood trauma with replication across two large, independent community-based samples

    Madden, R. A., Atkinson, K., Shen, X., Green, C., Hillary, R. F., Hawkins, E., Såge, E., Sandu, A-L., Waiter, G., McNeil, C., Harris, M., Campbell, A., Porteous, D., Macfarlane, J. A., Murray, A., Steele, D., Romaniuk, L., Lawrie, S. M., McIntosh, A. M. & Whalley, H. C., 26 Jan 2023, (E-pub ahead of print) In: European Psychiatry. p. 1-25 25 p.

    Research output: Contribution to journalArticlepeer-review

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  • Phenome-wide analysis identifies parent-of-origin effects on the human methylome associated with changes in the rate of aging

    Gao, C., Amador, C., Walker, R. M., Campbell, A., Madden, R. A., Adams, M. J., Bai, X., Liu, Y., Li, M., Hayward, C., Porteous, D. J., Shen, X., Evans, K. L., Haley, C. S., McIntosh, A. M., Navarro, P. & Zeng, Y., 20 Jan 2023, bioRxiv.

    Research output: Working paperPreprint

  • The impact of acute nutritional interventions on the plasma proteome

    Vernardis, S. I., Demichev, V., Lemke, O., Grüning, N-M., Messner, C., White, M., Pietzner, M., Peluso, A., Collet, T-H., Henning, E., Gille, C., Campbell, A., Hayward, C., Porteous, D. J., Marioni, R. E., Mülleder, M., Zelezniak, A., Wareham, N. J., Langenberg, C., Farooqi, I. S., & 1 othersRalser, M., 20 Jan 2023, (E-pub ahead of print) In: The Journal of Clinical Endocrinology & Metabolism (JCEM).

    Research output: Contribution to journalArticlepeer-review

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  • 2022

    Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

    Kanoni, S., Graham, S. E., Wang, Y., Surakka, I., Ramdas, S., Zhu, X., Clarke, S. L., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K-H. H., Ntalla, I., Hui, Q., Klarin, D., Hilliard, A. T., Wang, Z., Xue, C., & 519 othersThorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Hwang, M. Y., Han, S., Akiyama, M., Sakaue, S., Terao, C., Kanai, M., Zhou, W., Brumpton, B. M., Rasheed, H., Havulinna, A. S., Veturi, Y., Pacheco, J. A., Rosenthal, E. A., Lingren, T., Feng, Q., Kullo, I. J., Narita, A., Takayama, J., Martin, H. C., Hunt, K. A., Trivedi, B., Haessler, J., Giulianini, F., Bradford, Y., Miller, J. E., Campbell, A., Lin, K., Millwood, I. Y., Rasheed, A., Hindy, G., Faul, J. D., Zhao, W., Weir, D. R., Turman, C., Huang, H., Graff, M., Choudhury, A., Sengupta, D., Mahajan, A., Brown, M. R., Zhang, W., Yu, K., Schmidt, E. M., Pandit, A., Gustafsson, S., Yin, X., Luan, J., Zhao, J-H., Matsuda, F., Jang, H-M., Yoon, K., Medina-Gomez, C., Pitsillides, A., Hottenga, J. J., Wood, A. R., Ji, Y., Gao, Z., Haworth, S., Yousri, N. A., Mitchell, R. E., Chai, J. F., Aadahl, M., Bjerregaard, A. A., Yao, J., Manichaikul, A., Hwu, C-M., Hung, Y-J., Warren, H. R., Ramirez, J., Bork-Jensen, J., Kårhus, L. L., Goel, A., Sabater-Lleal, M., Noordam, R., Mauro, P., Matteo, F., McDaid, A. F., Marques-Vidal, P., Wielscher, M., Trompet, S., Sattar, N., Møllehave, L. T., Munz, M., Zeng, L., Huang, J., Yang, B., Poveda, A., Kurbasic, A., Lamina, C., Forer, L., Scholz, M., Galesloot, T. E., Bradfield, J. P., Ruotsalainen, S. E., Daw, EW., Zmuda, J. M., Mitchell, J. S., Fuchsberger, C., Christensen, H., Brody, J. A., Vazquez-Moreno, M., Feitosa, M. F., Wojczynski, M. K., Wang, Z., Preuss, M. H., Mangino, M., Christofidou, P., Verweij, N., Benjamins, J. W., Engmann, J., Tsao, N. L., Verma, A., Slieker, R. C., Lo, K. S., Zilhao, N. R., Le, P., Kleber, M. E., Delgado, G. E., Huo, S., Ikeda, D. D., Iha, H., Yang, J., Liu, J., Demirkan, A., Leonard, H. L., Marten, J., Frank, M., Schmidt, B., Smyth, L. J., Cañadas-Garre, M., Wang, C., Nakatochi, M., Wong, A., Hutri-Kähönen, N., Sim, X., Xia, R., Huerta-Chagoya, A., Fernandez-Lopez, J. C., Lyssenko, V., Nongmaithem, S. S., Bayyana, S., Stringham, H. M., Irvin, M. R., Oldmeadow, C., Kim, H-N., Ryu, S., Timmers, P. R. H. J., Arbeeva, L., Dorajoo, R., Lange, L. A., Prasad, G., Lorés-Motta, L., Pauper, M., Long, J., Li, X., Theusch, E., Takeuchi, F., Spracklen, C. N., Loukola, A., Bollepalli, S., Warner, S. C., Wang, Y. X., Wei, W. B., Nutile, T., Ruggiero, D., Sung, Y. J., Chen, S., Liu, F., Yang, J., Kentistou, K. A., Banas, B., Nardone, G. G., Meidtner, K., Bielak, L. F., Smith, J. A., Hebbar, P., Farmaki, A-E., Hofer, E., Lin, M., Concas, M. P., Vaccargiu, S., van der Most, P. J., Pitkänen, N., Cade, B. E., van der Laan, S. W., Chitrala, K. N., Weiss, S., Bentley, A. R., Doumatey, A. P., Adeyemo, A. A., Lee, J. Y., Petersen, E. R. B., Nielsen, A. A., Choi, H. S., Nethander, M., Freitag-Wolf, S., Southam, L., Rayner, N. W., Wang, C. A., Lin, S-Y., Wang, J-S., Couture, C., Lyytikäinen, L-P., Nikus, K., Cuellar-Partida, G., Vestergaard, H., Hidalgo, B., Giannakopoulou, O., Cai, Q., Obura, M. O., van Setten, J., Li, X., Liang, J., Tang, H., Terzikhan, N., Shin, J. H., Jackson, R. D., Reiner, A. P., Martin, L. W., Chen, Z., Li, L., Kawaguchi, T., Thiery, J., Bis, J. C., Launer, L. J., Li, H., Nalls, M. A., Raitakari, O. T., Ichihara, S., Wild, S. H., Nelson, C. P., Campbell, H., Jäger, S., Nabika, T., Al-Mulla, F., Niinikoski, H., Braund, P. S., Kolcic, I., Kovacs, P., Giardoglou, T., Katsuya, T., de Kleijn, D., de Borst, G. J., Kim, E. K., Adams, H. H. H., Ikram, M. A., Zhu, X., Asselbergs, F. W., Kraaijeveld, A. O., Beulens, J. W. J., Shu, X-O., Rallidis, L. S., Pedersen, O., Hansen, T., Mitchell, P., Hewitt, A. W., Kähönen, M., Pérusse, L., Bouchard, C., Tönjes, A., Chen, Y-D. I., Pennell, C. E., Mori, T. A., Lieb, W., Franke, A., Ohlsson, C., Mellström, D., Cho, Y. S., Lee, H., Yuan, J-M., Koh, W-P., Rhee, S. Y., Woo, J-T., Heid, I. M., Stark, K. J., Zimmermann, M. E., Völzke, H., Homuth, G., Evans, M. K., Zonderman, A. B., Polasek, O., Pasterkamp, G., Hoefer, I. E., Redline, S., Pahkala, K., Oldehinkel, A. J., Snieder, H., Biino, G., Schmidt, R., Schmidt, H., Bandinelli, S., Dedoussis, G., Thanaraj, T. A., Kardia, S. L. R., Peyser, P. A., Kato, N., Schulze, M. B., Girotto, G., Böger, C. A., Jung, B., Joshi, P. K., Bennett, D. A., De Jager, P. L., Lu, X., Mamakou, V., Brown, M., Caulfield, M. J., Munroe, P. B., Guo, X., Ciullo, M., Jonas, J. B., Samani, N. J., Kaprio, J., Pajukanta, P., Tusié-Luna, T., Aguilar-Salinas, C. A., Adair, L. S., Bechayda, S. A., de Silva, H. J., Wickremasinghe, A. R., Krauss, R. M., Wu, J-Y., Zheng, W., Hollander, A. I., Bharadwaj, D., Correa, A., Wilson, J. G., Lind, L., Heng, C-K., Nelson, A. E., Golightly, Y. M., Wilson, J. G., Penninx, B., Kim, H-L., Attia, J., Scott, R. J., Rao, D. C., Arnett, D. K., Hunt, S. C., Walker, M., Koistinen, H. A., Chandak, G. R., Mercader, J. M., Costanzo, M. C., Jang, D., Burtt, N. P., Villalpando, C. G., Orozco, L., Fornage, M., Tai, ES., van Dam, R. M., Lehtimäki, T., Chaturvedi, N., Yokota, M., Liu, J., Reilly, D. F., McKnight, A. J., Kee, F., Jöckel, K-H., McCarthy, M. I., Palmer, C. N. A., Vitart, V., Hayward, C., Simonsick, E., van Duijn, C. M., Jin, Z-B., Qu, J., Hishigaki, H., Lin, X., März, W., Gudnason, V., Tardif, J-C., Lettre, G., Hart, L. M. ., Elders, P. J. M., Damrauer, S. M., Kumari, M., Kivimaki, M., van der Harst, P., Spector, T. D., Loos, R. J. F., Province, M. A., Parra, E. J., Cruz, M., Psaty, B. M., Brandslund, I., Pramstaller, P. P., Rotimi, C. N., Christensen, K., Ripatti, S., Widén, E., Hakonarson, H., Grant, S. F. A., Kiemeney, L. A. L. M., de Graaf, J., Loeffler, M., Kronenberg, F., Gu, D., Erdmann, J., Schunkert, H., Franks, P. W., Linneberg, A., Jukema, J. W., Khera, A. V., Männikkö, M., Jarvelin, M-R., Kutalik, Z., Francesco, C., Mook-Kanamori, D. O., van Dijk, K. W., Watkins, H., Strachan, D. P., Grarup, N., Sever, P., Poulter, N., Chuang, L-M., Rotter, J. I., Dantoft, T. M., Karpe, F., Neville, M. J., Timpson, N. J., Cheng, C-Y., Wong, T-Y., Khor, C. C., Li, H., Sabanayagam, C., Peters, A., Gieger, C., Hattersley, A. T., Pedersen, N. L., Magnusson, P. K. E., Boomsma, D. I., Willemsen, A. H. M., Cupples, LA., van Meurs, J. B. J., Ghanbari, M., Gordon-Larsen, P., Huang, W., Kim, Y. J., Tabara, Y., Wareham, N. J., Langenberg, C., Zeggini, E., Kuusisto, J., Laakso, M., Ingelsson, E., Abecasis, G., Chambers, J. C., Kooner, J. S., de Vries, P. S., Morrison, A. C., Hazelhurst, S., Ramsay, M., North, K. E., Daviglus, M., Kraft, P., Martin, N. G., Whitfield, J. B., Abbas, S., Saleheen, D., Walters, R. G., Holmes, M. V., Black, C., Smith, B. H., Baras, A., Justice, A. E., Buring, J. E., Ridker, P. M., Chasman, D. I., Kooperberg, C., Tamiya, G., Yamamoto, M., van Heel, D. A., Trembath, R. C., Wei, W-Q., Jarvik, G. P., Namjou, B., Hayes, M. G., Ritchie, M. D., Jousilahti, P., Salomaa, V., Hveem, K., Åsvold, B. O., Kubo, M., Kamatani, Y., Okada, Y., Murakami, Y., Kim, B-J., Thorsteinsdottir, U., Stefansson, K., Zhang, J., Chen, YE., Ho, Y-L., Lynch, J. A., Rader, D. J., Tsao, P. S., Chang, K-M., Cho, K., O'Donnell, C. J., Gaziano, J. M., Wilson, P. W. F., Frayling, T. M., Hirschhorn, J. N., Kathiresan, S., Mohlke, K. L., Sun, Y. V., Morris, A. P., Boehnke, M., Brown, C. D., Natarajan, P., Deloukas, P., Willer, C. J., Assimes, T. L. & Peloso, G. M., 27 Dec 2022, In: Genome Biology. 23, 1, p. 268

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  • A saturated map of common genetic variants associated with human height

    23andMe Research Team, 12 Oct 2022, (E-pub ahead of print) In: Nature. 610, 7933, p. 704-712

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  • Global Biobank Meta-analysis Initiative: powering genetic discovery across human disease

    Hayward, C., Campbell, A., Porteous, D. J., Richmond, A. & Marioni, R. E., 12 Oct 2022, In: Cell Genomics.

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  • Feasibility and ethics of using data from the Scottish newborn blood spot archive for research

    Cunningham-Burley, S., McCartney, D. L., Campbell, A., Flaig, R., Orange, C. E. L., Porteous, C., Aitken, M., Mulholland, C. C., Davidson, S., McCafferty, S., Murphy, L., Wrobel, N., McCafferty, S., Wallace, K., St Clair, D., Kerr, S., Hayward, C., McIntosh, A. M., Sudlow, C. L. M., Marioni, R. E., & 3 othersPell, J., Miedzybrodzka, Z. & Porteous, D. J., 6 Oct 2022, In: Communications Medicine. 2, 8 p., 126.

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  • Associations of negative affective biases and depressive symptoms in a community-based sample

    De Nooij, L., Adams, M. J., Hawkins, E. L., Romaniuk, L., Munafò, M. R., Penton-voak, I. S., Elliott, R., Bland, A. R., Waiter, G. D., Sandu, A., Habota, T., Steele, J. D., Murray, A. D., Campbell, A., Porteous, D. J., Mcintosh, A. M. & Whalley, H. C., 21 Sept 2022, (E-pub ahead of print) In: Psychological Medicine. p. 1-10

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  • Reference ranges for NT-proBNP (N-Terminal Pro-B-Type Natriuretic Peptide) and risk factors for higher NT-proBNP concentrations in a large general population cohort

    Welsh, P., Campbell, R. T., Mooney, L., Kimenai, D. M., Hayward, C., Campbell, A., Porteous, D., Mills, N. L., Lang, N., Petrie, M. C., Januzzi, J. L., McMurray, J. J. V. & Sattar, N. A., 13 Sept 2022, (E-pub ahead of print) In: Circulation: Heart failure. 15, 11 p., e009427.

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  • Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

    Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J., Haessler, J., Lyytikäinen, L., Repetto, L., Concas, M. P., Van Den Berg, M. E., Weiss, S., Baldassari, A. R., Bartz, T. M., Cook, J. P., Evans, D. S., & 146 othersFreudling, R., Hines, O., Isaksen, J. L., Lin, H., Mei, H., Moscati, A., Müller-nurasyid, M., Nursyifa, C., Qian, Y., Richmond, A., Roselli, C., Ryan, K. A., Tarazona-santos, E., Thériault, S., Van Duijvenboden, S., Warren, H. R., Yao, J., Raza, D., Aeschbacher, S., Ahlberg, G., Alonso, A., Andreasen, L., Bis, J. C., Boerwinkle, E., Campbell, A., Catamo, E., Cocca, M., Cutler, M. J., Darbar, D., De Grandi, A., De Luca, A., Ding, J., Ellervik, C., Ellinor, P. T., Felix, S. B., Froguel, P., Fuchsberger, C., Gögele, M., Graff, C., Graff, M., Guo, X., Hansen, T., Heckbert, S. R., Huang, P. L., Huikuri, H. V., Hutri-kähönen, N., Ikram, M. A., Jackson, R. D., Junttila, J., Kavousi, M., Kors, J. A., Leal, T. P., Lemaitre, R. N., Lin, H. J., Lind, L., Linneberg, A., Liu, S., Macfarlane, P. W., Mangino, M., Meitinger, T., Mezzavilla, M., Mishra, P. P., Mitchell, R. N., Mononen, N., Montasser, M. E., Morrison, A. C., Nauck, M., Nauffal, V., Navarro, P., Nikus, K., Pare, G., Patton, K. K., Pelliccione, G., Pittman, A., Porteous, D. J., Pramstaller, P. P., Preuss, M. H., Raitakari, O. T., Reiner, A. P., Ribeiro, A. L. P., Rice, K. M., Risch, L., Schlessinger, D., Schotten, U., Schurmann, C., Shen, X., Shoemaker, M. B., Sinagra, G., Sinner, M. F., Soliman, E. Z., Stoll, M., Strauch, K., Tarasov, K., Taylor, K. D., Tinker, A., Trompet, S., Uitterlinden, A., Völker, U., Völzke, H., Waldenberger, M., Weng, L., Whitsel, E. A., Wilson, J. G., Avery, C. L., Conen, D., Correa, A., Cucca, F., Dörr, M., Gharib, S. A., Girotto, G., Grarup, N., Hayward, C., Jamshidi, Y., Järvelin, M., Jukema, J. W., Kääb, S., Kähönen, M., Kanters, J. K., Kooperberg, C., Lehtimäki, T., Lima-costa, M. F., Liu, Y., Loos, R. J. F., Lubitz, S. A., Mook-kanamori, D. O., Morris, A. P., O’connell, J. R., Olesen, M. S., Orini, M., Padmanabhan, S., Pattaro, C., Peters, A., Psaty, B. M., Rotter, J. I., Stricker, B., Van Der Harst, P., Van Duijn, C. M., Verweij, N., Wilson, J. G., Arking, D. E., Ramirez, J., Lambiase, P. D., Sotoodehnia, N., Mifsud, B., Newton-cheh, C. & Munroe, P. B., 1 Sept 2022, In: Nature Communications. 13, 1, 5144.

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  • Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning

    Lahti, J., Tuominen, S., Yang, Q., Pergola, G., Ahmad, S., Amin, N., Armstrong, N. J., Beiser, A., Bey, K., Bis, J. C., Boerwinkle, E., Bressler, J., Campbell, A., Campbell, H., Chen, Q., Corley, J., Cox, S. R., Davies, G., De Jager, P. L., Derks, E. M., & 103 othersFaul, J. D., Fitzpatrick, A. L., Fohner, A. E., Ford, I., Fornage, M., Gerring, Z., Grabe, H. J., Grodstein, F., Gudnason, V., Simonsick, E., Holliday, E. G., Joshi, P. K., Kajantie, E., Kaprio, J., Karell, P., Kleineidam, L., Knol, M. J., Kochan, N. A., Kwok, J. B., Leber, M., Lam, M., Lee, T., Li, S., Loukola, A., Luck, T., Marioni, R. E., Mather, K. A., Medland, S., Mirza, S. S., Nalls, M. A., Nho, K., O'Donnell, A., Oldmeadow, C., Painter, J., Pattie, A., Reppermund, S., Risacher, S. L., Rose, R. J., Sadashivaiah, V., Scholz, M., Satizabal, C. L., Schofield, P. W., Schraut, K. E., Scott, R. J., Simino, J., Smith, A. V., Smith, J. A., Stott, D. J., Surakka, I., Teumer, A., Thalamuthu, A., Trompet, S., Turner, S. T., van der Lee, S. J., Villringer, A., Völker, U., Wilson, R. S., Wittfeld, K., Vuoksimaa, E., Xia, R., Yaffe, K., Yu, L., Zare, H., Zhao, W., Ames, D., Attia, J., Bennett, D. A., Brodaty, H., Chasman, D. I., Goldman, A. L., Hayward, C., Ikram, M. A., Jukema, J. W., Kardia, S. L. R., Lencz, T., Loeffler, M., Mattay, V. S., Palotie, A., Psaty, B. M., Ramirez, A., Ridker, P. M., Riedel-Heller, S. G., Sachdev, P. S., Saykin, A. J., Scherer, M., Schofield, P. R., Sidney, S., Starr, J. M., Trollor, J., Ulrich, W., Wagner, M., Weir, D. R., Wilson, J. F., Wright, M. J., Weinberger, D. R., Debette, S., Eriksson, J. G., Mosley, T. H., Launer, L. J., van Duijn, C. M., Deary, I. J., Seshadri, S. & Räikkönen, K., 16 Aug 2022, (E-pub ahead of print) In: Molecular Psychiatry. 27, 11, p. 4419-4431

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  • Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health

    Gadd, D. A., Hillary, R. F., McCartney, D. L., Shi, L., Stolicyn, A., Robertson, N. A., Walker, R. M., McGeachan, R. I., Campbell, A., Xueyi, S., Barbu, M. C., Green, C., Morris, S. W., Harris, M. A., Backhouse, E. V., Wardlaw, J. M., Steele, J. D., Oyarzún, D. A., Muniz-Terrera, G., Ritchie, C., & 9 othersNevado-Holgado, A., Chandra, T., Hayward, C., Evans, K. L., Porteous, D. J., Cox, S. R., Whalley, H. C., McIntosh, A. M. & Marioni, R. E., 9 Aug 2022, In: Nature Communications. 13, 1, p. 4670

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