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Personal profile

Biography

Arpan is a Rowling Scholar (2017-) who subsequently secured an MRC Clinical Research Training Fellowship to undertake a PhD in laboratory research into motor neuron disease (MND), supervised by Professors Siddharthan Chandran and Giles Hardingham at the UK Dementia Research Institute. He is a neurology registrar from the Thames Valley deanery.

Arpan's Lady Edith Wolfson clinical fellowship, jointly funded by the Medical Research Council and the Motor Neurone Disease Association, examines the most common known genetic mutation in MND – the C9orf72 repeat expansion mutation. His research exploits recent advances in patient-derived stem cell modelling and gene-editing to better understand the molecular mechanisms underlying MND. The current focus of his research is on the role of defective metabolism as a mediator of dysfunctional axonal homeostasis.

Education/Academic qualification

BM BCh - New College, University of Oxford

MA - Gonville & Caius College, University of Cambridge

MRCP(UK)

External positions

MRC Lady Edith Wolfson Clinical Fellow, Medical Research Council

1 Aug 201731 Jan 2021

Keywords

  • RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
  • Neurology
  • Motor neuron disease
  • Amyotrophic lateral sclerosis

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