Arpan is a Rowling Scholar (2017-) who subsequently secured an MRC Clinical Research Training Fellowship to undertake a PhD in laboratory research into motor neuron disease (MND), supervised by Professors Siddharthan Chandran and Giles Hardingham at the UK Dementia Research Institute.  He was awarded his PhD in 2022, and is presently completing his neurology registar training at Queen Square, London, whilst continuing his research alongside his clinical commitments. 

Arpan's Lady Edith Wolfson clinical fellowship, jointly funded by the Medical Research Council and the Motor Neurone Disease Association, examined the most common known genetic mutation in MND – the C9orf72 repeat expansion mutation. His research exploits recent advances in patient-derived stem cell modelling and gene-editing to better understand the molecular mechanisms underlying MND. The current focus of his research is on the role of defective metabolism as a mediator of dysfunctional axonal homeostasis.

Arpan is also an ACORD ECR Fellow, hosted by the UCL Clinical Trials Unit, and is actively involved in the pioneering UK MND-SMART clinical trial, right from its launch in 2020.

Twitter handle: @DrArpan100