What I love in Science is that it raises new questions when it solves older ones. Neuroscience in particular grabbed my interest, as close it is to the sci-fi novels I was reading as a child.

I got my PhD degree in 2021 within the INSERM U1237 team at Normandy University, France. There, I used magnetic resonance imaging to investigate the glymphatic system, a perivascular route for brain waste drainage.

Now working as post-doctoral fellow under the supervision of Dr Axel Montagne, I am investigating how does ageing affect the blood brain barrier, with a specific interest in the vascular basement membrane.

During my free time, I enjoy reading encyclopedias, taking news from my family in France, playing video games and writing short novels.

Blood-brain barrier (BBB) disruption occurs in ageing and is associated with dementia. Endothelial cells and pericytes are closely associated actors of the brain vasculature. Dysfunctions of both cell types have been evidenced in ageing and dementia, though the precise mechanisms leading to BBB disruption are unknown. Vascular basement membrane constitute an acellular interface between these cells, whose degradation on ageing is related to pericyte loss and BBB rupture. In the Montagne Lab, I investigate the interplay between pericytes, vascular basement membrane and endothelial cells in a variety of in vivo and in vitro models, with MRI, electron microscopy, spinning disc confocal and 2-photon imaging.