Audrey Coutts

2023

Delayed mucosal anti-viral responses despite robust peripheral inflammation in fatal COVID-19

Sidhu, J. K., Siggins, M. K., Liew, F., Russell, C. D., Uruchurtu, A. S. S., Davis, C., Turtle, L., Moore, S. C., Hardwick, H. E., Oosthuyzen, W., Thomson, E. C., Semple, M. G., Baillie, J. K., Openshaw, P. J. M., Thwaites, R. S. & ISARIC4C Investigators, 22 Dec 2023, In: The Journal of Infectious Diseases. p. 1-13

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Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

ISARIC4C Investigators, 22 Dec 2023, In: Nature Communications. 14, 1, 8487.

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International Pediatric COVID-19 Severity Over the Course of the Pandemic

International Severe Acute Respiratory Infection Consortium (ISARIC4C) groupPediatric Active Enhanced Disease Surveillance (PAEDS) Network group, Baillie, K., Britton, P. N. & Short, K. R., 1 Oct 2023, In: JAMA pediatrics. 177, 10, p. 1073-1084 12 p.

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Adeno-associated virus 2 infection in children with non-A-E hepatitis

DIAMONDS consortium, Ho, A., Orton, R., Tayler, R., Asamaphan, P., Herder, V., Davis, C., Tong, L., Smollett, K., Manali, M., Allan, J., Rawlik, K., McDonald, S. E., Vink, E., Pollock, L., Gannon, L., Evans, C., McMenamin, J., Roy, K., Marsh, K., & 37 othersDivala, T., Holden, M. T. G., Lockhart, M., Yirrell, D., Currie, S., O'Leary, M., Henderson, D., Shepherd, S. J., Jackson, C., Gunson, R., MacLean, A., McInnes, N., Bradley-Stewart, A., Battle, R., Hollenbach, J., Henderson, P., Odam, M., Chikowore, P., Oosthuyzen, W., Chand, M., Hamilton, M. S., Estrada-Rivadeneyra, D., Levin, M., Avramidis, N., Pairo-Castineira, E., Vitart, V., Wilkie, C., Palmarini, M., Ray, S., Robertson, D. L., da Silva Filipe, A., Willett, B. J., Breuer, J., Semple, M. G., Turner, D., Baillie, J. K. & Thomson, E. C., May 2023, In: Nature. 617, 7961, p. 555-563 25 p.

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Genomic investigations of unexplained acute hepatitis in children

DIAMONDS consortium, Chikowore, P. & Baillie, K., May 2023, In: Nature. 617, 7961, p. 564-573 36 p.

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GWAS and meta-analysis identifies 49 genetic variants underlying critical Covid-19

GenOMICC Investigators, SCOURGE Consortium, ISARIC4C Investigators, 23andMe Covid-19 Team, Pairo-Castineira, E., Rawlik, K., Bretherick, A. D., Qi, T., Wu, Y., Nassiri, I., McConkey, G. A., Zechner, M., Klaric, L., Griffiths, F., Oosthuyzen, W., Kousathanas, A., Richmond, A., Millar, J., Russell, C. D., Malinauskas, T., & 39 othersThwaites, R., Morrice, K., Keating, S., Maslove, D. M., Nichol, A. D., Semple, M. G., Knight, J., Shankar-Hari, M., Summers, C., Hinds, C., Horby, P., Ling, L., McAuley, D. F., Montgomery, H., Openshaw, P. J. M., Begg, C., Walsh, T. S., Tenesa, A., Flores, C., Riancho, J. A., Rojas-Martinez, A., Lapunzina, P., Yang, J., Ponting, C. P., Wilson, J. F., Vitart, V., Abedalthagafi, M. S., Luchessi, A., Parra, E. J., Cruz, R., Carracedo, A., Fawkes, A., Murphy, L., Rowan, K., Pereira, A. C., Law, A., Fairfax, B. P., Clohisey Hendry, S. & Baillie, J. K., May 2023, In: Nature. 617, 7962, p. 764-768 30 p.

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The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection

ISARIC4C Investigators, Baillie, J. K. & Digard, P., 13 Mar 2023, (E-pub ahead of print) In: Genome Biology. 24, 1, p. 1-23 22 p., 47.

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2022

SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination

ISARIC4C Investigators, Liew, F., Talwar, S., Cross, A., Willett, B. J., Scott, S., Logan, N., Siggins, M. K., Swieboda, D., Sidhu, J. K., Efstathiou, C., Moore, S. C., Davis, C., Mohamed, N., Nunag, J., King, C., Thompson, A. A. R., Rowland-Jones, S. L., Docherty, A. B., Chalmers, J. D., & 22 othersHo, L-P., Horsley, A., Raman, B., Poinasamy, K., Marks, M., Kon, O. M., Howard, L., Wootton, D. G., Dunachie, S., Quint, J. K., Evans, R. A., Wain, L. V., Fontanella, S., de Silva, T. I., Ho, A., Harrison, E., Baillie, J. K., Semple, M. G., Brightling, C., Thwaites, R. S., Turtle, L. & Openshaw, P. J. M., 16 Dec 2022, (E-pub ahead of print) In: EBioMedicine. p. 104402

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Whole genome sequencing reveals host factors underlying critical Covid-19

GenOMICC Investigators, Kousathanas, A., Pairo-Castineira, E., Rawlik, K., Stuckey, A., Odhams, C. A., Walker, S., Russell, C. D., Malinauskas, T., Wu, Y., Millar, J., Shen, X., Elliott, K. S., Griffiths, F., Oosthuyzen, W., Morrice, K., Keating, S., Wang, B., Rhodes, D., Klaric, L., & 57 othersZechner, M., Parkinson, N., Siddiq, A., Goddard, P., Donovan, S., Maslove, D., Nichol, A., Semple, M. G., Zainy, T., Maleady-Crowe, F., Todd, L., Salehi, S., Knight, J., Elgar, G., Chan, G., Arumugam, P., Patch, C., Rendon, A., Bentley, D., Kingsley, C., Kosmicki, J. A., Horowitz, J. E., Baras, A., Abecasis, G. R., Ferreira, M. A. R., Justice, A., Mirshahi, T., Oetjens, M., Rader, D. J., Ritchie, M. D., Verma, A., Fowler, T. A., Shankar-Hari, M., Summers, C., Hinds, C., Horby, P., Ling, L., McAuley, D., Montgomery, H., Openshaw, P. J. M., Elliott, P., Walsh, T., Tenesa, A., Fawkes, A., Murphy, L., Rowan, K., Ponting, C. P., Vitart, V., Wilson, J. F., Yang, J., Bretherick, A. D., Scott, R. H., Hendry, S. C., Moutsianas, L., Law, A., Caulfield, M. J. & Baillie, J. K., 7 Jul 2022, In: Nature. 607, p. 97-103

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SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses

OPTIC Consortium, 3 Feb 2022, In: Cell. 185, 3, p. 467-484.e15

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2021

Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity

WES/WGS Working Group Within the HGI, 10 Dec 2021, (E-pub ahead of print) In: Human Genetics.

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Mapping the human genetic architecture of COVID-19

COVID-19 Host Genetics Initiative, Baillie, J. K., Wilson, J. F., Bulteel, N., Hayward, C., Klaric, L., Porteous, D. J., Russell, C. D., Tenesa, A., Norman, L., Scott-Brown, J. & Swann, O., 8 Jul 2021, (E-pub ahead of print) In: Nature.

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Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice.

Bell, R., Villalobos, E., Nixon, M., Miguelez-Crespo1, A., Murphy, L., Fawkes, A., Coutts, A., Sharp, M. G., Koerner, M., Allan, E., Meijer, O. C., Houtman, R., Odermatt, A., Beck, K. R., Denham, S. G., Lee, P., Homer, N., Walker, B. R. & Morgan, R. A., Jun 2021, In: Molecular Metabolism. 48, 101225.

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2015

DNA immunoprecipitation semiconductor sequencing (DIP-SC-seq) as a rapid method to generate genome wide epigenetic signatures

Thomson, J. P., Fawkes, A., Ottaviano, R., Hunter, J. M., Shukla, R., Mjoseng, H. K., Clark, R., Coutts, A., Murphy, L. & Meehan, R. R., 18 May 2015, In: Scientific Reports. 5, 9778.

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Audrey Coutts

Research output

Search results