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Personal profile


Barry joined the Institute of Animal Health Neuropathogenesis Unit (IAH-NPU) in 2000. Here he worked on transmissible spongiform encephalopathy (TSE) or prion infectious agents. Barry has been responsible for undergraduate and postgraduate training since 2012 and was most recently promoted to Lecturer in 2021. His research aims to identify how various cell types are involved in the maintenance of brain health and responses to neuroinflammation and neurodegeneration such as during prion infection.

Research students


Sasha Pokrovskaya 2023-

Emma Green (Advisor) 2020-

Reiss Pal 2020-2023


Clara Gomez-Dunlop 2022

Joe Reynolds 2020

Christianus Wijaya 2019


Lauryn Walmsley-Rowe 2023

Claire Banner 2022

Rebecca Bruce 2021

Danica Ariyadasa-Sáez 2019

Laura Tetlow 2016

Caroline Wood 2015

Lester Thoo 2014

Kah Yap 2013

Mark Laloo 2013

Matthew Helsby 2012


Current Research Interests

Analysis of the role of specific immune cells and mediators in 
prion pathogenesis, including during co-infections. 
Understanding the basis of immune priming and the nature and 
consequences of immune responses to pathogens in vivo. 
Development of strategies to potentiate immunity. 

My research in a nutshell

Prion diseases are prototypical protein-misfolding neurodegenerative disorders. Using this model we study how protein-misfolding within the brain results in activation of the supporting glia cells, impacts upon brain function and ultimately leads to loss of the connections (synapses) and death of brain cells (neurons). The goal of my research is to understand how this happens and how other infections and activation of the immune system may influence neurodegeneration. the ultimate goal of my research is to identify potential therapeutic treatments for these currently untreatable conditions.

Education/Academic qualification

Doctor of Philosophy (PhD), The University of Edinburgh


Award Date: 14 Jul 2016

Neuroscience, Master of Science, University of Edinburgh


Bachelor of Science (Honours), The University of Edinburgh



  • RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
  • Neurodegeneration
  • Prion diseases
  • Dementia
  • Glia
  • QR180 Immunology
  • Innate immunity
  • Dendritic cells
  • Myeloid heamatopoeisis
  • QH426 Genetics
  • Conditional transgenesis

College Research Themes

  • College of Medicine and Veterinary Medicine


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