Bartlomiej Waclaw

Phone+44 (0) 131 651 7688
Emailbwaclawstaffmail.ed.acuk
Websitehttp://www2.ph.ed.ac.uk/~bwaclaw/

Accepting PhD Students

PhD projects

I can offer projects in the area of biophysics/statistical physics. In particular, I am interested in exploring links between the physics of bacteria and biological evolution, and genetic heterogeneity in tumours. These projects can be either theoretical, experimental, or both. Theoretical projects will combine statistical-physics modelling of genetically diverse cellular populations, cell-cell and cell-environment interactions, and will involve molecular-dynamics simulations on multiple scales: from biomolecules to individual bacterial cells to macroscopic populations of cells. Experimental research will focus on how physical properties of bacteria and their environment affect fixation probabilities of drug-resistant mutants. All projects will involve collaborations with world-leading researchers from Edinburgh, Europe, and USA.

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5 results
- Title
- Start date(ascending)

Rapid Evolution of Colistin Resistance in a Bioreactor Model of Infection of Klebsiella pneumoniae
Dorai-Schneiders, T. (Creator), Waclaw, B. (Creator), Jiménez-Castellanos, J. (Creator) & Meynert, A. (Creator), Edinburgh DataShare, 31 Jan 2023
DOI: 10.7488/ds/3800, https://doi.org/10.1101/2022.10.03.510619
Dataset
Experimental data for the article "Predictable Properties of Fitness Landscapes Induced by Adaptational Tradeoffs"
Waclaw, B. (Creator), Oliveira Lebre Direito, S. (Creator), Das, S. (Creator), Allen, R. (Creator) & Krug, J. (Creator), Edinburgh DataShare, 23 Jan 2020
DOI: 10.7488/ds/2756, https://www.biorxiv.org/content/10.1101/2020.01.15.908574v1
Dataset
Resonant noise amplification in a predator-prey model with quasi-discrete generations
Waclaw, B. (Creator) & Giannakou, M. (Creator), Edinburgh DataShare, 26 Apr 2023
DOI: 10.7488/ds/3844, https://doi.org/10.48550/arXiv.2301.13290
Dataset
Data accompanying the manuscript "Mechanical interactions in bacterial colonies and the surfing probability of beneficial mutations"
Waclaw, B. (Creator), Gralka, M. (Creator), Hallatschek, O. (Creator) & Farrell, F. (Creator), Edinburgh DataShare, 5 Feb 2017
DOI: 10.7488/ds/1702, http://datashare.is.ed.ac.uk/handle/10283/840
Dataset
Supplementary data for the manuscript "Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic"
Webb, S. (Creator), Ramsahoye, B. (Creator), Pusch, O. (Creator), Yu, M. (Creator), Greulich, P. (Creator), Bird, A. (Creator), Chhatbar, K. (Creator), Waclaw, B. (Creator), Cholewa-Waclaw, J. (Creator) & Shah, R. (Creator), Edinburgh DataShare, 7 Jun 2019
DOI: 10.7488/ds/2568
Dataset

Bartlomiej Waclaw

Datasets

Search results

Rapid Evolution of Colistin Resistance in a Bioreactor Model of Infection of Klebsiella pneumoniae

Experimental data for the article "Predictable Properties of Fitness Landscapes Induced by Adaptational Tradeoffs"

Resonant noise amplification in a predator-prey model with quasi-discrete generations

Data accompanying the manuscript "Mechanical interactions in bacterial colonies and the surfing probability of beneficial mutations"

Supplementary data for the manuscript "Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic"