Personal profile
Education/Academic qualification
Biotechnology, Bachelor of Engineering, Anna University, Chennai
Neurobiology, Doctor of Philosophy (PhD), Role of CNTF/STAT3 signalling in modulating axon growth and maintenance in the context of motor neuron degeneration, University of Würzburg
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Collaborations and top research areas from the last five years
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Syntaphilin loss enhances mitochondrial axonal transport and neuromuscular junction formation in a human stem cell derived neuromuscular assembloid model
Salzinger, A., Özkan, E., Ramesh, V., Nanda, J., Burr, K., Story, D., Pham, N. T., Chandran, S. & Selvaraj, B. T., 5 Nov 2025, (E-pub ahead of print) In: Molecular Medicine. 31, 1, p. 328Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A multimodal screening platform for endogenous dipeptide repeat proteins in C9orf72 patient iPSC neurons
Hölbling, B. V., Gupta, Y., Marchi, P. M., Atilano, M. L., Flower, M., Ureña, E., Goulden, R. A., Dobbs, H. K., Katona, E., Mikheenko, A., Giblin, A., Awan, A. R., Fisher-Ward, C. L., O'Brien, N., Vaizoglu, D., Kempthorne, L., Wilson, K. M., Gittings, L. M., Carcolé, M. & Ruepp, M.-D. & 9 others, , 10 May 2025, (E-pub ahead of print) In: Cell Reports. 44, 5, p. 115695Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The Fragile X Messenger Ribonucleoprotein 1 Regulates the Morphology and Maturation of Human and Rat Oligodendrocytes
Ramesh, V., Tsoukala, E., Kougianou, I., Kozic, Z., Burr, K., Viswanath, B., Hampton, D., Story, D., Reddy, B. K., Pal, R., Dando, O., Kind, P. C., Chattarji, S., Selvaraj, B. T., Chandran, S. & Zoupi, L., 10 Feb 2025, (E-pub ahead of print) In: Glia.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Safety and efficacy of memantine and trazodone versus placebo for motor neuron disease (MND SMART): stage two interim analysis from the first cycle of a phase 3, multiarm, multistage, randomised, adaptive platform trial
Pal, S., Chataway, J., Swingler, R., Macleod, M. R., Carragher, N. O., Hardingham, G., Selvaraj, B. T., Smith, C., Wong, C., Newton, J., Lyle, D., Stenson, A., Dakin, R. S., Ihenacho, A., Colville, S., Mehta, A. R., Stallard, N., Carpenter, J. R., Parker, R. A. & Keerie, C. & 10 others, , 1 Nov 2024, In: The Lancet Neurology. 23, 11, p. 1097-1107Research output: Contribution to journal › Article › peer-review
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Role of glia in delirium: proposed mechanisms and translational implications
Heffernan, Á. B., Steinruecke, M., Dempsey, G., Chandran, S., Selvaraj, B. T., Jiwaji, Z. & Stavrou, M., 27 Oct 2024, (E-pub ahead of print) In: Molecular Psychiatry.Research output: Contribution to journal › Review article › peer-review
Open AccessFile
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Validation of DPP6 as a novel therapeutic target for ALS
T Selvaraj, B. (Principal Investigator)
UK Dementia Research Institute Ltd
1/10/25 → 30/09/27
Project: Research
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Exploiting state-of-the-art mass spectrometry to identify blood-based biomarkers for TDP-43 driven Motor Neuron Disease
T Selvaraj, B. (Principal Investigator) & Pal, S. (Co-investigator)
17/03/25 → 16/09/26
Project: Research
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Validation of DPP6 as a novel therapeutic target for ALS
T Selvaraj, B. (Principal Investigator)
4/03/25 → 3/03/28
Project: Research
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Identifying adeno-associated viruses to successfully and specifically target human glia
Diaz-Castro, B. (Principal Investigator), Durrant, C. (Co-investigator), Hasel, P. (Co-investigator), T Selvaraj, B. (Co-investigator) & Williams, A. (Co-investigator)
UK Dementia Research Institute Ltd
6/01/25 → 5/10/26
Project: Research
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Identification of therapeutic combinations to reverse TDP43 mediated RNA dysfunction using high-throughput DRUG-Seq platform on human stem cell derived models
T Selvaraj, B. (Principal Investigator), Carragher, N. (Co-investigator), Chandran, S. (Co-investigator), Graham, R. (Co-investigator), Hardingham, G. (Co-investigator), Newton, J. (Co-investigator) & Pal, S. (Co-investigator)
Motor Neurone Disease Association
1/10/24 → 31/10/26
Project: Research