Research output per year
Research output per year
Personal profile
Education/Academic qualification
Molecular Biology, Doctor of Philosophy (PhD), University of Edinburgh
Award Date: 1 Mar 2001
Genetics, Bachelor of Science, Trinity College Dublin, Ireland.
Award Date: 1 Jul 1996
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Dive into the research topics where Brian McHugh is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Cathelicidin is a “fire alarm”, generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa
McHugh, B. J., Wang, R., Li, H.-N., Beaumont, P. E., Kells, R., Stevens, H., Young, L., Rossi, A. G., Gray, R. D., Dorin, J. R., Gwyer Findlay, E. L., Brough, D. & Davidson, D. J., 12 Apr 2019, In: PLoS Pathogens. 15, 4, e1007694.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy
Findlay, E. G., Currie, A. J., Zhang, A., Ovciarikova, J., Young, L., Stevens, H., McHugh, B. J., Canel, M., Gray, M., Milling, S. W. F., Campbell, J. D. M., Savill, J., Serrels, A. & Davidson, D. J., 1 May 2019, (E-pub ahead of print) In: OncoImmunology. p. 1-17Research output: Contribution to journal › Article › peer-review
Open AccessFile -
An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade
Vuong, L., Kouverianou, E., Rooney, C. M., McHugh, B. J., Howie, S. E. M., Gregory, C. D., Forbes, S. J., Henderson, N. C., Zetterberg, F. R., Nilsson, U. J., Leffler, H., Ford, P., Pedersen, A., Gravelle, L., Tantawi, S., Schambye, H., Sethi, T. & MacKinnon, A. C., 1 Apr 2019, In: Cancer Research. 79, 7, p. 1480-1492Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Blood Neutrophils are Reprogrammed in Bronchiectasis
Bedi, P., Davidson, D. J., McHugh, B. J., Rossi, A. G. & Hill, A. T., 1 Oct 2018, In: American Journal of Respiratory and Critical Care Medicine. 198, 7, p. 880-890Research output: Contribution to journal › Article › peer-review
Open AccessFile -
IL-1beta-induced protection of keratinocytes against Staphylococcus aureus-secreted proteases is mediated by human beta defensin 2
Wang, B., McHugh, B. J., Qureshi, A., Campopiano, D. J., Clarke, D. J., Fitzgerald, J. R., Dorin, J. R., Weller, R. & Davidson, D. J., Jan 2017, In: Journal of Investigative Dermatology. 137, 1, p. 95-105Research output: Contribution to journal › Article › peer-review
Open AccessFile
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Mitochondrial dysfunction in macrophages and impaired bacterial clearance in chronic obstructive pulmonary disease (COPD)
Dockrell, D. (Principal Investigator), McHugh, B. (Co-investigator), Walmsley, S. (Co-investigator) & Whyte, M. (Co-investigator)
1/06/22 → 31/05/27
Project: Research
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Human beta-defensin in Atopic Dermatitis: dissecting the mechanism of a novel, targetable, protection against barrier damage.
Davidson, D. (Principal Investigator), Dorin, J. (Co-investigator), McHugh, B. (Co-investigator) & Weller, R. (Co-investigator)
1/09/18 → 31/12/21
Project: Research
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Edinburgh Dermatology Research Fund - “Novel antiproteases in atopic dermatitis”
McHugh, B. (Co-investigator) & Davidson, D. (Co-investigator)
13/12/13 → 12/12/14
Project: University Awarded Project Funding
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Characterisation of FAM38A, a novel integrin activator in lung cancer
McHugh, B. (Principal Investigator) & Sethi, T. (Co-investigator)
UK central government bodies/local authorities, health and hospital authorities
1/04/09 → 30/04/11
Project: Research
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Investigating the protease activity of a novel protein involved in chromosome architecture in Drosophilia melanogaster
Heck, M. (Principal Investigator) & McHugh, B. (Co-investigator)
1/11/00 → 31/10/02
Project: Research